clonidine and oxymetazoline

clonidine has been researched along with oxymetazoline in 99 studies

Research

Studies (99)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (54.55)	18.7374
1990's	29 (29.29)	18.2507
2000's	16 (16.16)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B	1
Timmermans, PB; van Zwieten, PA	1
Esbenshade, TA; Han, C; Hollinger, S; Minneman, KP; Theroux, TL	1
Bonhaus, DW; Chang, LK; Chang, TK; Daunt, DA; Eglen, RM; Hsu, SA; Jasper, JR; Lesnick, JD; Yamanishi, SS	1
Harms, GS; Lohse, MJ; Steinmeyer, R; Vilardaga, JP	1
Agbaba, D; Filipic, S; Nikolic, K	1
Kobinger, W; Pichler, L	2
Gillan, MG; Kosterlitz, HW; Robson, LE; Waterfield, AA	1
Johansson, P	1
Ganong, WF; Morris, BJ; Reid, IA	1
Brown, DA; Caulfield, MP	1
Tayo, FM	1
Endo, T; Starke, K; Taube, HD	1
Daly, JW; Skolnick, P	1
Bentley, GA; Nolan, PL	1
Nolan, PL; Reid, IA	1
Wikberg, J	1
Rolls, ET; Shaw, SG	1
Bradley, ME; Buxton, IL; Keef, KD; Zhang, L	1
Sperlágh, B; Vizi, ES	1
Andrioli, GC; Bonanno, G; Maura, G; Pende, M; Raiteri, M; Ruelle, A	1
Latifpour, J; Nishimoto, T; Weiss, RM; Yoshida, M	1
Hoyer, D; Schoeffter, P	1
Hellström, PM; Svensson, TH; Thollander, M	2
Bhandare, PN; D'Souza, RS; Rataboli, PV	1
Gleason, MM; Hieble, JP	1
Castillo, C; Hong, E; Valencia, I	1
Chandranath, SI; Gokhale, SD; Sharif, SI	1
Hadjiconstantinou, M; Krajnc, D; Neff, NH; Rossetti, Z	1
Ladwein, E; Szrama, E; Wessler, I	1
Davis, M; Gallager, DW; Kehne, JH	1
Nobin, A; Owman, C; Törnebrandt, K	1
Jonkman, FA; Man, PW; Thoolen, MJ; van Zwieten, PA	1
Al-Saffar, A; Eriksson, U; Hellström, PM; Svensson, TH; Thollander, M	1
Diop, L; Kolta, A; Reader, TA	1
Izumi, F; Wada, A; Yanagihara, N	1
Bylund, DB	1
Ilhan, M; Long, JP	1
Kobinger, W	2
Ishii, K; Kato, R; Muraki, T	1
de Champlain, J; Foucart, S; Nadeau, R	1
Franco-Cereceda, A; Lundberg, JM; Nagata, M; Svensson, TH	1
Altmann, KP; Starke, K	1
Schmitt, H; Tsoucaris-Kupfer, D	1
Le Douarec, JC; Petillot, N; Schmitt, H	1
Jones, DJ; McKenna, LF	1
Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG	1
Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG; Scatton, B	1
Kato, R; Muraki, T; Nakadate, T; Nakaki, T	1
Armstrong, JM; Cavero, I; Lefèvre-Borg, F; Scatton, B	1
Kato, R; Nakadate, T; Nakaki, T; Yamamoto, S	1
Bentley, GA; Newton, SH; Starr, J	1
Digges, KG; Summers, RJ	1
Andersson, KE; Norgren, L; Skärby, TV; Steen, S	1
Kessar, P; Saggerson, ED	1
De Jong, AP; Soudijn, W	1
Andersson, KE; Edvinsson, L; Skärby, TV	1
Robie, NW	1
Ahn, JN; Keil, LC; Reid, IA; Shackelford, R; Trinh, T; Weintraub, M	1
Commissaris, RL; Davis, M; Kehne, JH; Lakoski, J; Marwaha, J; Shaw, W	1
Fray, JC; Karuza, AS	1
Livnat, A; Schultz, HD; Zehr, JE	1
Malta, E; Raper, C; Tawa, PE	1
McCulloch, MW; Medgett, IC; Rand, MJ; Story, DF	1
Ogihara, M	1
Duarte, J; Jiménez, J; Pérez-Vizcaíno, F; Tamargo, J; Zarzuelo, A	1
Daniel, EE; Hoo, KH; Kwan, CY	1
Alburges, ME; Bylund, DB; Pundt, LL; Wamsley, JK	1
Chen, MJ; Chiu, TH; Tang, FI; Yang, JJ; Yang, YR	1
Kiem, DT; Makara, GB; Vizi, ES	1
Endoh, M; Yang, HT	1
Coupar, IM; Liu, L	1
Dan, K; Hirose, H; Maruyama, H; Nakamura, K; Saruta, T; Seto, Y	1
Duda, T; Sharma, RK; Venkataraman, V	1
Kobayashi, H; Miyazaki, T; Tosaka, T	1
Arimitsu, M; Karaki, H; Koga, Y; Mitsui-Saito, M; Ozaki, H; Sato, K	1
Ohia, SE; Opere, CA	1
Gazelius, B; Hellström, PM; Thollander, M	1
Hébert, CA; Kudo, LH; Rouch, AJ	1
Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P	1
Akagi, Y; Muramatsu, I; Nakamura, S; Suzuki, F; Taniguchi, T	1
Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K	1
Shannon, HE; Womer, DE	1
Colpaert, FC; Pauwels, PJ	1
Keef, KD; Mutafova-Yambolieva, VN	1
Kimura, S; Kontani, H; Tsuji, T	1
Gaivin, RJ; Gonzalez-Cabrera, P; Perez, DM; Ross, SA; Waugh, DJ; Yun, J; Zuscik, MJ	1
Simonsen, U; Wikberg-Matsson, A	1
Fülöp, K; Fürst, S; Gyires, K; Müllner, K; Rónai, AZ	1
Mest, HJ; Scheltdorf, M	1
Arévalo-León, LE; Gallardo-Ortíz, IA; Urquiza-Marín, H; Villalobos-Molina, R	1
Kang, BY; Kim, TS; Lee, SW	1
Fülöp, K; Gyires, K; Rónai, AZ; Zádori, Z	1
Dunkel, P; Fülöp, K; Gyires, K; Shujaa, N; Zádori, ZS	1
Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T	1

Reviews

3 review(s) available for clonidine and oxymetazoline

Article	Year
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs. Journal of medicinal chemistry, 1982, Volume: 25, Issue:12 Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses	1982
Heterogeneity of alpha-2 adrenergic receptors. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:5 Topics: Animals; Blood Platelets; Brain; Cerebral Cortex; Clonidine; Corpus Striatum; Dogs; Guinea Pigs; Humans; Oxymetazoline; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Species Specificity; Submandibular Gland; Yohimbine	1985
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2 Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine	1986

Other Studies

96 other study(ies) available for clonidine and oxymetazoline

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction	1984
Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Molecular pharmacology, 1994, Volume: 46, Issue:5 Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Binding, Competitive; Catecholamines; Cattle; Cell Line; Cloning, Molecular; Cricetinae; Humans; Imidazoles; Inositol Phosphates; Phenethylamines; Phenoxybenzamine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Tetralones	1994
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. Biochemical pharmacology, 1998, Apr-01, Volume: 55, Issue:7 Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cyclic AMP; Genetic Vectors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Protein Binding; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Proteins	1998
Molecular basis of inverse agonism in a G protein-coupled receptor. Nature chemical biology, 2005, Volume: 1, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Cell Line; Fluorescence Resonance Energy Transfer; Humans; Ligands; Protein Binding; Receptors, Adrenergic, alpha-2; Receptors, G-Protein-Coupled; Signal Transduction	2005
QSAR study of imidazoline antihypertensive drugs. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship	2008
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers. Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 291, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine	1975
The inhibitory effects of presynaptic alpha-adrenoceptor agonists on contractions of guinea-pig ileum and mouse vas deferens in the morphine-dependent and withdrawn states produced in vitro. British journal of pharmacology, 1979, Volume: 66, Issue:4 Topics: Adenosine Diphosphate; Adrenergic alpha-Agonists; Animals; Clonidine; Drug Implants; Drug Interactions; Epinephrine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Synapses; Vas Deferens	1979
Antagonistic effects of synthetic alpha adrenoceptor agonists on isolated artery strips from the cod, Gadus morhua. Comparative biochemistry and physiology. C: Comparative pharmacology, 1979, Volume: 63C, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; Fishes; Imidazoles; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Propranolol	1979
Inhibition by alpha-adrenoceptor agonists of renin release in vitro. European journal of pharmacology, 1979, Oct-26, Volume: 59, Issue:1-2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Depression, Chemical; Epinephrine; In Vitro Techniques; Isoproterenol; Kidney; Male; Methoxamine; Norepinephrine; Oxymetazoline; Phentolamine; Phenylephrine; Propranolol; Rats; Renin	1979
Hyperpolarizing 'alpha 2'-adrenoceptors in rat sympathetic ganglia. British journal of pharmacology, 1979, Volume: 65, Issue:3 Topics: Animals; Catecholamines; Clonidine; Ganglia, Autonomic; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Oxymetazoline; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Time Factors	1979
Prejunctional inhibitory alpha-adrenoceptors and dopaminoceptors of the rat vas deferens and the guinea-pig ileum in vitro. European journal of pharmacology, 1979, Sep-15, Volume: 58, Issue:2 Topics: Animals; Apomorphine; Clonidine; Dopamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Norepinephrine; Oxymetazoline; Pimozide; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Vas Deferens; Yohimbine	1979
Pre- and postsynaptic components in effect of drugs with alpha adrenoceptor affinity. Nature, 1975, Apr-03, Volume: 254, Issue:5499 Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Corticosterone; In Vitro Techniques; Methoxamine; Muscle Contraction; Neurons; Norepinephrine; Oxymetazoline; Phenylephrine; Propranolol; Pulmonary Artery; Rabbits; Receptors, Adrenergic; Synapses	1975
Stimulation of adenosine 3',5'-monophosphate formation by alpha and beta adrenergic agonists in rat cerebral cortical slices: effects of clonidine. Molecular pharmacology, 1975, Volume: 11, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Rats, Inbred F344; Stimulation, Chemical	1975
Studies on orthostatic cardiovascular responses in anaesthetized cats. Clinical and experimental pharmacology & physiology, 1975, Volume: Suppl 2 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Bretylium Compounds; Cats; Clonidine; Guanethidine; Hemodynamics; Hypotension, Orthostatic; Norepinephrine; Oxymetazoline; Time Factors; Xylazine	1975
Mechanism of suppression of renin secretion by clonidine in the dog. Circulation research, 1978, Volume: 42, Issue:2 Topics: Animals; Blood Pressure; Clonidine; Dogs; Female; Injections, Intravenous; Male; Oxymetazoline; Pentolinium Tartrate; Renin	1978
Differentiation between pre- and postjunctional alpha-receptors in guinea pig ileum and rabbit aorta. Acta physiologica Scandinavica, 1978, Volume: 103, Issue:3 Topics: Animals; Aorta, Thoracic; Cimetidine; Clonidine; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Oxymetazoline; Parasympathetic Nervous System; Phenoxybenzamine; Phentolamine; Phenylephrine; Rabbits; Receptors, Adrenergic; Tolazoline	1978
Is the release of noradrenaline necessary for self-stimulation of the brain? Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:4 Topics: Amphetamine; Animals; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Clonidine; Disulfiram; Levodopa; Male; Naphazoline; Nerve Endings; Norepinephrine; Oxymetazoline; Phenylephrine; Rats; Receptors, Drug; Reserpine; Self Stimulation	1976
Proceedings: Central nervous cardiovascular depression, a potential action of alpha-adrenoceptors stimulating imidazoline derivatives. Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287 Suppl Topics: Animals; Cardiovascular System; Cats; Clonidine; Dogs; Imidazoles; Medulla Oblongata; Naphazoline; Oxymetazoline	1975
Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon. The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1 Topics: Adenylate Cyclase Toxin; Animals; Binding, Competitive; Cell Membrane; Clonidine; Colforsin; Colon; Dogs; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine	1992
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation? Neuroscience, 1992, Volume: 51, Issue:1 Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine	1992
Subclassification of release-regulating alpha 2-autoreceptors in human brain cortex. British journal of pharmacology, 1992, Volume: 107, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Calcium; Cerebral Cortex; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Oxymetazoline; Receptors, Adrenergic, alpha; Tetrodotoxin	1992
Pharmacological characterization of alpha adrenergic receptors in the young and old female rabbit urethra. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Calcium; Clonidine; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Oxymetazoline; Rabbits; Receptors, Adrenergic, alpha; Urethra	1991
Interaction of the alpha-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors. European journal of pharmacology, 1991, Apr-17, Volume: 196, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Brain; Cattle; Clonidine; In Vitro Techniques; Kinetics; Methiothepin; Oxymetazoline; Phentolamine; Rats; Receptors, Serotonin; Swine	1991
Suppression of castor oil-induced diarrhoea by alpha 2-adrenoceptor agonists. Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Castor Oil; Clonidine; Diarrhea; Electromyography; Gastrointestinal Motility; Intestine, Small; Male; Oxymetazoline; Rats; Rats, Inbred Strains	1991
Dual action of clonidine on ethanol-induced gastric lesions: is the imidazoline-preferring receptor involved? European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Ethanol; Guanabenz; Imidazoline Receptors; Male; Methyldopa; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Stomach; Yohimbine	1991
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine	1991
Contractile and relaxant effects of alpha-adrenergic agonists on rat aorta. Proceedings of the Western Pharmacology Society, 1991, Volume: 34 Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phenylephrine; Rats	1991
Pharmacological characterization of the postjunctional alpha-adrenoceptors of the rat isolated seminal vesicle. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Naphazoline; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seminal Vesicles; Yohimbine	1990
Modulation of retinal aromatic L-amino acid decarboxylase via alpha 2 adrenoceptors. Journal of neurochemistry, 1989, Volume: 52, Issue:2 Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Clonidine; Cycloheximide; Darkness; Dihydroxyphenylalanine; Kinetics; Light; Male; Oxymetazoline; Phentolamine; Piperoxan; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Retina; Yohimbine	1989
Stimulation of alpha 1-adrenoceptors increases electrically evoked [3H]acetylcholine release from the rat phrenic nerve. European journal of pharmacology, 1989, Dec-12, Volume: 174, Issue:1 Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; Oxymetazoline; Phenylephrine; Phrenic Nerve; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Yohimbine	1989
Suppression of small intestinal motility and morphine withdrawal diarrhoea by clonidine: peripheral site of action. Acta physiologica Scandinavica, 1989, Volume: 137, Issue:3 Topics: Animals; Clonidine; Diarrhea; Gastrointestinal Motility; Intestine, Small; Male; Morphine; Morphine Dependence; Naloxone; Oxymetazoline; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome	1989
Spinalization unmasks clonidine's alpha 1-adrenergic mediated excitation of the flexor reflex in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:6 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Nerve Block; Oxymetazoline; Procaine; Rats; Rats, Inbred Strains; Reflex; Spinal Cord	1985
Pharmacological characterization of alpha-adrenergic receptor subtypes mediating contraction in human mesenteric arteries and veins. Blood vessels, 1985, Volume: 22, Issue:4 Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Drug Interactions; Female; Humans; Male; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phentolamine; Prazosin; Vasodilation; Yohimbine	1985
Location of the mechanism of the clonidine withdrawal tachycardia in rats. The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:8 Topics: Animals; Blood Pressure; Clonidine; Injections, Intraventricular; Injections, Subcutaneous; Male; Oxymetazoline; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tachycardia; Time Factors; Yohimbine	1985
Alpha2-adrenoceptor agonists inhibit the migrating myoelectric complexes of the small intestine in rats. Acta physiologica Scandinavica, 1987, Volume: 130, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Gastrointestinal Motility; Intestine, Small; Male; Morphine; Naloxone; Oxymetazoline; Rats; Rats, Inbred Strains	1987
Noradrenergic effects on rat visual cortex: single-cell microiontophoretic studies of alpha-2 adrenergic receptors. Life sciences, 1987, Jul-20, Volume: 41, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Male; Neurons; Norepinephrine; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Visual Cortex	1987
Effects of alpha 2-adrenergic agonists on carbachol-stimulated catecholamine synthesis in cultured bovine adrenal medullary cells. Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22 Topics: 2-Hydroxyphenethylamine; Adrenal Medulla; Adrenergic alpha-Agonists; Animals; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Guanidines; Octopamine; Oxymetazoline; Phenylacetates; Tyrosine; Tyrosine 3-Monooxygenase; Yohimbine	1987
Clonidine-induced desensitization differentiates presynaptic alpha-2 adrenoceptors of the guinea-pig ileum and rat vas deferens. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:2 Topics: Animals; Clonidine; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Oxymetazoline; Rats; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine	1985
Effects of clonidine and yohimbine on plasma cyclic nucleotide levels in clonidine-naive and clonidine-treated mice. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 280, Issue:2 Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Hexamethonium Compounds; Injections, Intraperitoneal; Male; Mice; Oxymetazoline; Propranolol; Time Factors; Yohimbine	1986
The release of catecholamines from the adrenal medulla and its modulation by alpha 2-adrenoceptors in the anaesthetized dog. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:4 Topics: Adrenal Medulla; Animals; Catecholamines; Clonidine; Dioxanes; Dogs; Dopamine; Electric Stimulation; Epinephrine; Female; Idazoxan; Male; Norepinephrine; Oxymetazoline; Receptors, Adrenergic, alpha; Splanchnic Nerves; Yohimbine	1987
Differential effects of clonidine and reserpine treatment on neuropeptide Y content in some sympathetically innervated tissues of the guinea-pig. European journal of pharmacology, 1987, Oct-13, Volume: 142, Issue:2 Topics: Adrenal Glands; Animals; Clonidine; Guinea Pigs; Heart Atria; Hypothalamus; Male; Muscles; Neuropeptide Y; Oxymetazoline; Reserpine; Spleen; Sympathetic Nervous System	1987
Inhibition of adrenergic neurotransmission by clonidine: an action on prejunctional -receptors. Neuropharmacology, 1973, Volume: 12, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Heart; In Vitro Techniques; Mathematics; Oxymetazoline; Phenoxybenzamine; Phentolamine; Rabbits; Receptors, Adrenergic; Sympathetic Nervous System; Synaptic Transmission	1973
Hypothermic effect of alpha-sympathomimetic agents and their antagonism by adrenergic and cholinergic blocking drugs. Neuropharmacology, 1972, Volume: 11, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aniline Compounds; Animals; Body Temperature; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Hypothalamus; Injections; Injections, Intraperitoneal; Naphazoline; Oxazoles; Oxymetazoline; Parasympatholytics; Rats; Stereotaxic Techniques; Sympatholytics; Thiazines; Time Factors; Toluidines; Xylenes	1972
Antinociceptive effects of some alpha-sympathomimetic agents. Neuropharmacology, 1974, Volume: 13, Issue:5 Topics: Analgesics; Aniline Compounds; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Imidazoles; Injections, Intraperitoneal; Naphazoline; Naphthalenes; Oxazoles; Oxymetazoline; Rats; Reaction Time; Reflex, Startle; Sympathomimetics; Tetrazoles; Thiazines; Toluidines; Vocalization, Animal	1974
Alpha adrenergic receptor mediated formation of cyclic AMP in rat spinal cord. Journal of cyclic nucleotide research, 1980, Volume: 6, Issue:2 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cyclic AMP; Male; Methoxamine; Naphazoline; Oxymetazoline; Phenylephrine; Rats; Spinal Cord	1980
Pharmacological evidence favoring a similarity between alpha adrenoceptors mediating sleep in chicks and cardiac presynaptic alpha-2 receptors in rats. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chickens; Clonidine; Guanfacine; Guanidines; Heart; Heart Rate; Male; Methoxamine; Nordefrin; Oxymetazoline; Phentolamine; Phenylacetates; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Sleep; Xylazine; Yohimbine	1982
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Clonidine; Dogs; Female; Heart; Heart Rate; Imidazoles; Male; Norepinephrine; Oxymetazoline; Pentobarbital; Quinoxalines; Rats; Spinal Cord; Synapses; Tachycardia; Vagotomy	1982
Inhibitory alpha 2-adrenergic mechanism regulating gastric secretion in pylorus-ligated rats. Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Brain Chemistry; Catecholamines; Clonidine; Gastric Juice; Hydroxydopamines; Injections, Intraventricular; Male; Oxymetazoline; Pylorus; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1982
Urethane inhibits cardiovascular responses mediated by the stimulation of alpha-2 adrenoceptors in the rat. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:2 Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Clonidine; Epinephrine; Heart Rate; Kinetics; Male; Norepinephrine; Oxymetazoline; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Urethane; Vagotomy; Vagus Nerve	1982
Central blood pressure regulation. Involvement of presynaptic or postsynaptic, alpha 1- or alpha 2-adrenoceptors? Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Cats; Clonidine; Dogs; Heart Rate; Medulla Oblongata; Oxymetazoline; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses	1983
Protection against alloxan-induced diabetes in mice by stimulation of alpha 2-adrenergic receptors. Life sciences, 1983, Feb-14, Volume: 32, Issue:7 Topics: Adrenergic alpha-Agonists; Alloxan; Animals; Clonidine; Diabetes Mellitus, Experimental; Epinephrine; Male; Mice; Mice, Inbred Strains; Oxymetazoline; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stimulation, Chemical	1983
Studies on the antinociceptive action of alpha-agonist drugs and their interactions with opioid mechanisms. British journal of pharmacology, 1983, Volume: 79, Issue:1 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Drug Interactions; Drug Tolerance; Male; Mice; Mice, Inbred BALB C; Naloxone; Oxymetazoline; Receptors, Opioid	1983
Characterization of postsynaptic alpha-adrenoceptors in rat aortic strips and portal veins. British journal of pharmacology, 1983, Volume: 79, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Female; Male; Muscle, Smooth, Vascular; Nordefrin; Oxymetazoline; Phenethylamines; Portal Vein; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Yohimbine	1983
Pharmacological characterization of postjunctional alpha-adrenoceptors in isolated human omental arteries and veins. Acta physiologica Scandinavica, 1984, Volume: 120, Issue:1 Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Clonidine; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Omentum; Oxymetazoline; Phenylephrine; Prazosin; Veins; Yohimbine	1984
Evidence that catecholamines stimulate renal gluconeogenesis through an alpha 1-type of adrenoceptor. The Biochemical journal, 1980, Jul-15, Volume: 190, Issue:1 Topics: Animals; Clonidine; Gluconeogenesis; Imidazoles; In Vitro Techniques; Kidney Cortex; Male; Methoxamine; Moxisylyte; Norepinephrine; Oxymetazoline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine	1980
Relationships between structure and alpha-adrenergic receptor affinity of clonidine and some related cyclic amidines. European journal of pharmacology, 1981, Jan-16, Volume: 69, Issue:2 Topics: Amidines; Animals; Binding, Competitive; Clonidine; In Vitro Techniques; Oxymetazoline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship	1981
Pharmacological characterization of postjunctional alpha-adrenoceptors in isolated feline cerebral and peripheral arteries. Acta physiologica Scandinavica, 1983, Volume: 117, Issue:1 Topics: Animals; Arteries; Cats; Cerebral Arteries; Clonidine; Female; Male; Mesenteric Arteries; Methoxamine; Norepinephrine; Oxymetazoline; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1983
Controversial evidence regarding the functional importance of presynaptic alpha receptors. Federation proceedings, 1984, Volume: 43, Issue:5 Topics: Animals; Clonidine; Dogs; Electric Stimulation; Heart; Heart Rate; Kidney; Norepinephrine; Oxymetazoline; Phentolamine; Receptors, Adrenergic, alpha; Synapses; Vasoconstriction; Yohimbine	1984
Mechanism of suppression of vasopressin and adrenocorticotropic hormone secretion by clonidine in anesthetized dogs. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Clonidine; Dogs; Female; Injections, Intra-Arterial; Injections, Intravenous; Injections, Intraventricular; Male; Oxymetazoline; Vagotomy; Vasopressins; Yohimbine	1984
Spinal clonidine inhibits neural firing in locus coeruleus. Brain research, 1983, Oct-16, Volume: 276, Issue:2 Topics: Animals; Clonidine; Hydroxydopamines; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Oxidopamine; Oxymetazoline; Rats; Rats, Inbred Strains; Spinal Cord	1983
Influence of raising albumin concentration on renin release in isolated perfused rat kidneys. The Journal of physiology, 1980, Volume: 299 Topics: Animals; Calcium; Clonidine; In Vitro Techniques; Isoproterenol; Kidney; Male; Natriuresis; Oxymetazoline; Perfusion; Pressure; Propranolol; Rats; Renin; Secretory Rate; Serum Albumin, Bovine	1980
Central and peripheral adrenergic modulation of carotid sinus-induced renin release. The American journal of physiology, 1982, Volume: 242, Issue:3 Topics: Animals; Blood Pressure; Carotid Sinus; Clonidine; Dogs; Female; Heart Rate; Kidney; Male; Oxymetazoline; Propranolol; Reflex; Renin	1982
Pre- and postjunctional effects of clonidine- and oxymetazoline-like compounds in guinea-pig ileal preparations. British journal of pharmacology, 1981, Volume: 73, Issue:2 Topics: Acetylcholine; Animals; Clonidine; Electric Stimulation; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Oxymetazoline	1981
Structure-activity relationship of imidazolidine derivatives related to clonidine at histamine H2-receptors in guinea-pig isolated atria. British journal of pharmacology, 1980, Volume: 69, Issue:3 Topics: Animals; Clonidine; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; In Vitro Techniques; Male; Oxymetazoline; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Structure-Activity Relationship	1980
Expression of alpha 2-receptor-mediated responses by insulin in primary culture of rat hepatocytes. Japanese journal of pharmacology, 1995, Volume: 68, Issue:1 Topics: Animals; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Cycloheximide; Drug Interactions; Glucagon; Glucose; Insulin; Liver; Male; Oxymetazoline; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors	1995
Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta. General pharmacology, 1993, Volume: 24, Issue:6 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminophylline; Animals; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Clonidine; Female; Gallopamil; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Oxymetazoline; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha	1993
Investigation of alpha 1-adrenoceptor subtypes in canine aorta, using alkylating agents. Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:1 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Aorta; Binding, Competitive; Clonidine; Dioxanes; Dogs; Female; In Vitro Techniques; Male; Mesenteric Veins; Muscle, Smooth, Vascular; Oxymetazoline; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1	1994
Alpha 2-agonist binding sites in brain: [125I]para-iodoclonidine versus [3H]para-aminoclonidine. Brain research bulletin, 1993, Volume: 32, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Binding, Competitive; Brain; Clonidine; Iodine Radioisotopes; Isoquinolines; Male; Oxymetazoline; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tritium	1993
Action of dexmedetomidine on rat locus coeruleus neurones: intracellular recording in vitro. European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Barium Compounds; Cesium; Chlorides; Clonidine; Electrophysiology; Imidazoles; In Vitro Techniques; Locus Coeruleus; Male; Medetomidine; Membrane Potentials; Neurons; Oxymetazoline; Parasympathetic Fibers, Postganglionic; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine	1995
Hypothalamic alpha 2A-adrenoceptors stimulate growth hormone release in the rat. European journal of pharmacology, 1995, Dec-04, Volume: 287, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Dioxanes; Growth Hormone-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Male; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Somatostatin	1995
(+/-)-tamsulosin, an alpha 1A-adrenoceptor antagonist, inhibits the positive inotropic effect but not the accumulation of inositol phosphates in rabbit heart. European journal of pharmacology, 1996, Oct-03, Volume: 312, Issue:3 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Inositol Phosphates; Male; Myocardial Contraction; Myocardium; Oxymetazoline; Rabbits; Sulfonamides; Tamsulosin; Tritium	1996
Characterisation of pre- and post-synaptic alpha-adrenoceptors in modulation of the rat ileum longitudinal and circular muscle activities. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Clonidine; Electric Stimulation; Idazoxan; Ileum; In Vitro Techniques; Muscle Contraction; Oxymetazoline; Phentolamine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Presynaptic	1997
Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:10 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Glucose; GTP-Binding Proteins; Humans; Imidazoles; Indoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Molecular Structure; Oxymetazoline; Pancreatic Neoplasms; Pertussis Toxin; Phentolamine; Pyrroles; Quinolizines; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella	1997
A role for amino acid residues in the third cytoplasmic loop in defining the ligand binding characteristics of the alpha2D-adrenergic receptor. Molecular and cellular biochemistry, 1997, Volume: 177, Issue:1-2 Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Clonidine; COS Cells; Cytoplasm; Epinephrine; Humans; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxymetazoline; Phentolamine; Prazosin; Protein Binding; Rats; Receptors, Adrenergic, alpha-2; Sequence Alignment; Yohimbine	1997
Presynaptic inhibition by noradrenaline of the EPSC evoked in neonatal rat sympathetic preganglionic neurons. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Animals, Newborn; Clonidine; Excitatory Postsynaptic Potentials; Glutamic Acid; Norepinephrine; Organ Culture Techniques; Oxymetazoline; Patch-Clamp Techniques; Phenylephrine; Prazosin; Presynaptic Terminals; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord	1998
Mechanism of relaxant effect of clonidine in isolated bovine tracheal smooth muscle. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cyclic AMP; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxymetazoline; Phentolamine; Trachea	1998
Prejunctional alpha2-adrenoceptors and peroxide-induced potentiation of norepinephrine release from the bovine iris. Neurochemical research, 1998, Volume: 23, Issue:8 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Brimonidine Tartrate; Cattle; Clonidine; Culture Techniques; Hydrogen Peroxide; Iris; Neuroeffector Junction; Norepinephrine; Oxymetazoline; Perfusion; Quinoxalines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Tritium; Yohimbine	1998
Adrenergic modulation of small bowel haemodynamics in interdigestive motility state of man. European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Clonidine; Duodenum; Fasting; Gastrointestinal Motility; Hemodynamics; Humans; Isoproterenol; Jejunum; Laser-Doppler Flowmetry; Male; Manometry; Myoelectric Complex, Migrating; Oxymetazoline; Pressure; Propranolol; Receptors, Adrenergic; Regional Blood Flow	1999
Inhibition of water permeability in the rat collecting duct: effect of imidazoline and alpha-2 compounds. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Arginine Vasopressin; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Imidazoles; Kidney Tubules, Collecting; Medetomidine; Oxazoles; Oxymetazoline; Permeability; Rats; Rats, Wistar; Rilmenidine; Water	1999
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine	1999
Evaluation of alpha1-adrenoceptors in the rabbit iris: pharmacological characterization and expression of mRNA. British journal of pharmacology, 1999, Volume: 127, Issue:6 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Gene Expression; In Vitro Techniques; Indoles; Iris; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium	1999
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature. European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine	2000
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10 Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Lidocaine; Male; Mice; Morphine; Oxymetazoline; Pain; Pain Measurement; Pertussis Toxin; Temperature; Virulence Factors, Bordetella	2000
Partial to complete antagonism by putative antagonists at the wild-type alpha(2C)-adrenoceptor based on kinetic analyses of agonist:antagonist interactions. British journal of pharmacology, 2000, Volume: 131, Issue:7 Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Azepines; Brimonidine Tartrate; Calcium; CHO Cells; Clonidine; Cricetinae; DNA, Recombinant; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Idazoxan; Kinetics; Medetomidine; Mice; Oxymetazoline; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Transfection	2000
Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery. European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Neuromuscular Junction; Oxymetazoline; Phentolamine; Pyridoxal Phosphate; Receptors, Adrenergic, alpha-2; Reserpine; Suramin; Yohimbine	2001
Effects of adrenergic alpha2-receptor agonists on urinary bladder contraction in conscious rats. Japanese journal of pharmacology, 2000, Volume: 84, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Male; Muscle Contraction; Oxymetazoline; Rats; Rats, Wistar; Urinary Bladder	2000
Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like antagonists. The Journal of biological chemistry, 2001, Jul-06, Volume: 276, Issue:27 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cell Membrane; Clonidine; Conserved Sequence; Cricetinae; Dihydropyridines; Dioxanes; Humans; Imidazoles; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Phenylalanine; Piperazines; Prazosin; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship	2001
Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries. Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:9 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Ciliary Arteries; Clonidine; Dose-Response Relationship, Drug; Isometric Contraction; Muscle, Smooth, Vascular; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha-2; Swine; Vasoconstriction	2001
Involvement of central K(ATP) channels in the gastric antisecretory action of alpha2-adrenoceptor agonists and beta-endorphin in rats. European journal of pharmacology, 2002, Jan-25, Volume: 435, Issue:2-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; beta-Endorphin; Central Nervous System; Clonidine; Gastric Acid; Gastric Mucosa; Glyburide; Hypoglycemic Agents; Ligation; Male; Membrane Proteins; Oxymetazoline; Potassium Channels; Pylorus; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach	2002
Pertussis toxin converts hyperpolarizations caused by alpha(2)-adrenoceptor agonists containing an imidazoline moiety into depolarizations in MIN 6 cells. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Cell Line; Clonidine; Epinephrine; Imidazoles; Insulin; Membrane Potentials; Mice; Oxymetazoline; Pertussis Toxin; Receptors, Adrenergic, alpha-2	2002
Evidence for the role of alpha1D- and alpha1A-adrenoceptors in contraction of the rat mesenteric artery. Vascular pharmacology, 2003, Volume: 40, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1	2003
Stimulation of interleukin-12 production in mouse macrophages via activation of p38 mitogen-activated protein kinase by alpha2-adrenoceptor agonists. European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3 Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Enzyme Activation; Female; Guanfacine; In Vitro Techniques; Interleukin-12; Macrophages; Mice; Mice, Inbred DBA; Mitogen-Activated Protein Kinases; Oxymetazoline; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen	2003
Characterisation of alpha2-adrenoceptor subtypes involved in gastric emptying, gastric motility and gastric mucosal defence. European journal of pharmacology, 2005, Dec-28, Volume: 528, Issue:1-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Yohimbine	2005
Pre- and postsynaptic mechanisms in the clonidine- and oxymetazoline-induced inhibition of gastric motility in the rat. Neurochemistry international, 2007, Volume: 51, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Insulin; Isoindoles; Male; Muscarinic Agonists; Muscle Contraction; Oxymetazoline; Prazosin; Rats; Rats, Wistar; Receptors, Presynaptic; Stomach; Synapses	2007
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor. Anesthesia and analgesia, 2008, Volume: 107, Issue:1 Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine	2008