clonidine and oxycodone

clonidine has been researched along with oxycodone in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's4 (26.67)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Sandyk, R1
Charney, DS; Kleber, HD1
Niemi, L1
Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z1
Andurkar, SV; Bhalla, S; Gulati, A1
Ewan, EE; Martin, TJ1
Bhagat, DD; Curren, J; Goon, AK; Goytizolo, EA; Jules-Elysee, KM; Kahn, RL; Lin, Y; Ma, Y; Mayman, DJ; Padgett, DE; Ranawat, AS; Ranawat, CS; Reid, SC; Westrich, GH; YaDeau, JT1
Bremer, N; Dizdarevic, A1
Bint, L; Czarniak, P; Landwehr, C; Parsons, R; Richardson, J; Sunderland, B1
Beardsley, PM; Carper, M; Contreras, KM; Damaj, MI; Walentiny, DM1

Reviews

1 review(s) available for clonidine and oxycodone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for clonidine and oxycodone

ArticleYear
Effects of intrathecal clonidine on duration of bupivacaine spinal anaesthesia, haemodynamics, and postoperative analgesia in patients undergoing knee arthroscopy.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Anesthesia, Spinal; Arthroscopy; Blood Pressure; Bupivacaine; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Ketoprofen; Knee Joint; Male; Middle Aged; Oxycodone; Pain, Postoperative

1994
Patient-controlled epidural analgesia or multimodal pain regimen with periarticular injection after total hip arthroplasty: a randomized, double-blind, placebo-controlled study.
    The Journal of bone and joint surgery. American volume, 2015, May-20, Volume: 97, Issue:10

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, Hip; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intra-Articular; Length of Stay; Male; Middle Aged; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Treatment Outcome

2015

Other Studies

12 other study(ies) available for clonidine and oxycodone

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Tourette syndrome: successful treatment with clonidine and oxycodone.
    Journal of neurology, 1986, Volume: 233, Issue:3

    Topics: Adolescent; Clonidine; Codeine; Drug Therapy, Combination; Humans; Male; Oxycodone; Tourette Syndrome

1986
Iatrogenic opiate addiction: successful detoxification with clonidine.
    The American journal of psychiatry, 1980, Volume: 137, Issue:8

    Topics: Clonidine; Codeine; Female; Humans; Middle Aged; Opioid-Related Disorders; Oxycodone; Pain, Intractable; Substance Withdrawal Syndrome

1980
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
    Pharmacology, 2009, Volume: 83, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine

2009
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
    Pharmacology, 2011, Volume: 87, Issue:3-4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine

2011
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward

2011
Cervical Spinal Cord Stimulation with Concomitant Serotonin Norepinephrine Reuptake Inhibitor Therapy Leading to the Serotonin Syndrome.
    Pain medicine (Malden, Mass.), 2017, 06-01, Volume: 18, Issue:6

    Topics: Adult; Analgesics; Cervical Vertebrae; Clonidine; Complex Regional Pain Syndromes; Diclofenac; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; Humans; Lamotrigine; Male; Oxycodone; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Spinal Cord Stimulation

2017
Cross-sectional survey of off-label and unlicensed prescribing for inpatients at a paediatric teaching hospital in Western Australia.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Australia; Child; Child, Preschool; Clonidine; Drug Administration Routes; Drug Prescriptions; Female; Humans; Inpatients; Isoxazoles; Legislation, Drug; Male; Midazolam; Off-Label Use; Oxycodone; Pediatrics

2019
Validation and characterization of oxycodone physical dependence in C57BL/6J mice.
    European journal of pharmacology, 2021, Jul-15, Volume: 903

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Substance Withdrawal Syndrome

2021