clonidine and ondansetron

clonidine has been researched along with ondansetron in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's8 (33.33)29.6817
2010's9 (37.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cheng, CH; Costall, B; Ge, J; Naylor, RJ1
Münke, H; Ramadori, G; Schwörer, H; Stöckmann, F1
Kamato, T; Miyata, K; Nagakura, Y; Naitoh, Y; Yamano, M1
Bertschy, G; Cucchia, AT; Ferrero, F; Monnat, M; Spagnoli, J1
Gupta, YK; Kacker, V; Mehta, VS1
Barrett, VJ; Bountra, C; Butler, A; Cambridge, D; Clayton, NM; Gale, J; Humphrey, PP; Hunt, AA; Maxwell, MP; Sargent, R1
Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E1
Dukat, M; Wesołowska, A1
Dkhar, SA; Naveen, AT; Peddyreddy, MK; Ramaswamy, S; Shewade, DG1
Beer, GM; Goldscheider, E; Lehmann, K; Weber, A1
Eisenach, JC; Hayashida, K; Hobo, S; Kimura, M; Obata, H; Yoshizumi, M1
Eshghpour, M; Hashemipour, MS; Hosseini-Abrishami, M; Mianbandi, V; Samieirad, S; Shadkam, E; Sharifian-Attar, A1
Barnett, BS; Suzuki, J; Ward, HB1
Aletraris, L; Paino, M; Roman, PM1

Reviews

1 review(s) available for clonidine and ondansetron

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for clonidine and ondansetron

ArticleYear
Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery.
    Anesthesiology, 2002, Volume: 96, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; Anesthesia, General; Antiemetics; Blood Pressure; Breast Neoplasms; Clonidine; Droperidol; Female; Heart Rate; Humans; Injections, Intravenous; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Risk Factors

2002
Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial.
    Medicina oral, patologia oral y cirugia bucal, 2018, Nov-01, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Analgesics; Antiemetics; Clonidine; Double-Blind Method; Female; Humans; Male; Ondansetron; Orthognathic Surgical Procedures; Pain, Postoperative; Postoperative Nausea and Vomiting; Treatment Outcome; Young Adult

2018

Other Studies

21 other study(ies) available for clonidine and ondansetron

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5-HT release in the frontal cortex of freely-moving rats.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonidine; Dialysis; Diazepam; Drug Interactions; Extracellular Space; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Yohimbine

1993
Treatment of diarrhea in carcinoid syndrome with ondansetron, tropisetron, and clonidine.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:4

    Topics: Antiemetics; Clonidine; Diarrhea; Humans; Indoles; Male; Malignant Carcinoid Syndrome; Middle Aged; Ondansetron; Tropisetron

1995
Compounds possessing 5-HT3 receptor antagonistic activity inhibit intestinal propulsion in mice.
    European journal of pharmacology, 1996, Sep-05, Volume: 311, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cholinesterase Inhibitors; Cisapride; Clonidine; Gastrointestinal Transit; Intestines; Male; Mice; Mice, Inbred C57BL; Neostigmine; Ondansetron; Piperidines; Receptors, Serotonin; Serotonin Antagonists

1996
Ultra-rapid opiate detoxification using deep sedation with oral midazolam: short and long-term results.
    Drug and alcohol dependence, 1998, Nov-01, Volume: 52, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Anesthesia, General; Clonidine; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Heroin Dependence; Humans; Hypnotics and Sedatives; Length of Stay; Male; Methadone; Midazolam; Naltrexone; Narcotic Antagonists; Neurologic Examination; Ondansetron; Substance Withdrawal Syndrome; Treatment Outcome

1998
Acute intracranial hypertension-induced inhibition of gastric emptying: evaluation in conscious rats.
    European journal of pharmacology, 1999, Mar-12, Volume: 369, Issue:1

    Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Antihypertensive Agents; Antipsychotic Agents; Bretylium Compounds; Carbachol; Cisapride; Clonidine; Consciousness; Female; Gastric Emptying; Gastrointestinal Agents; Intracranial Hypertension; Intracranial Pressure; Male; Ondansetron; Prazosin; Rats; Rats, Wistar; Reference Values; Stomach

1999
The pharmacological properties of the novel selective 5-HT3 receptor antagonist, alosetron, and its effects on normal and perturbed small intestinal transit in the fasted rat.
    Neurogastroenterology and motility, 1999, Volume: 11, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Carbolines; Clonidine; Drug Evaluation, Preclinical; Fasting; Gastrointestinal Transit; Intestine, Small; Ondansetron; Ovalbumin; Radioligand Assay; Rats; Reference Values; Reflex; Serotonin Antagonists; Vagus Nerve

1999
Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.
    European journal of pharmacology, 2005, Dec-28, Volume: 528, Issue:1-3

    Topics: Analgesics; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Indoles; Male; Mice; Mice, Inbred ICR; Models, Animal; Motor Activity; Ondansetron; Pain; Pain Measurement; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Time Factors; Tropisetron

2005
An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice.
    World journal of gastroenterology, 2006, Apr-28, Volume: 12, Issue:16

    Topics: Animals; Atropine; Calcium Channels; Clonidine; Gastrointestinal Transit; Glyburide; Insulin; Insulin Secretion; Intestine, Small; Male; Mice; Naloxone; Ondansetron; Receptors, Opioid; Verapamil

2006
Prevention of acute hematoma after face-lifts.
    Aesthetic plastic surgery, 2010, Volume: 34, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Antiemetics; Antihypertensive Agents; Clonidine; Female; Hematoma; Humans; Male; Middle Aged; Ondansetron; Postoperative Care; Preoperative Care; Rhytidoplasty

2010
Ondansetron reverses antihypersensitivity from clonidine in rats after peripheral nerve injury: role of γ-aminobutyric acid in α2-adrenoceptor and 5-HT3 serotonin receptor analgesia.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesia; Animals; Clonidine; Disease Models, Animal; gamma-Aminobutyric Acid; Male; Ondansetron; Pain; Pain Management; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin, 5-HT3; Serotonin Antagonists

2012
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.
    Substance abuse, 2019, Volume: 40, Issue:2

    Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics

2019
The use of off-label medications in substance abuse treatment programs.
    Substance abuse, 2020, Volume: 41, Issue:3

    Topics: Accreditation; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antiemetics; Baclofen; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; Gabapentin; Health Facility Size; Humans; Logistic Models; Off-Label Use; Ondansetron; Practice Patterns, Physicians'; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors; Topiramate; United States; Valproic Acid

2020