clonidine has been researched along with ng-nitroarginine methyl ester in 39 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 11 (28.21) | 18.2507 |
2000's | 23 (58.97) | 29.6817 |
2010's | 5 (12.82) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Schott, C; Stoclet, JC; Topouzis, S | 1 |
Ishizaka, H; Matsunaga, T; Okumura, K; Tsunoda, R; Yasue, H | 1 |
Ferrell, WR; Najafipour, H | 1 |
Giraldo, J; Tabernero, A; Vila, E | 1 |
Kimes, AS; London, ED; Vaupel, DB | 1 |
Shen, H; Virag, L; Vulliemoz, Y | 1 |
Björnberg, J; Ekelund, U; Mellander, S | 1 |
Czuczwar, SJ; Dzieciuch, JA; Kleinrok, Z; Przesmycki, K | 1 |
Fukuzawa, M; Hara, S; Kuroda, T; Ono, N; Yatomi, Y | 1 |
Balfagón, G; Ferrer, M; Marín, J; Tejera, N | 1 |
Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A; Głód, R | 1 |
Castro Resende, AC; Leão, MC; Lima, AF; Mesquita Ferreira, AG; Moreira, CF; Nunes, FR; Sena, KM; Silveira, SS; Soares de Moura, RS | 1 |
Garvin, JL; Plato, CF | 1 |
Bohr, DF; Cabrera, CL; Dobrucki, LW; Malinski, T | 1 |
Correia, ML; de Lemos Neto, M; de Oliveira, LF; Resende, AC; Rios, AA; Santos, EJ; Soares de Moura, R; Tano, T | 1 |
Fayaz-Dastgerdi, M; Homayoun, H; Khavandgar, S; Zarrindast, MR | 1 |
Cheng, JT; Chuang, YC; Lin, CR; Wang, CJ; Yang, LC | 1 |
Penner, SB; Smyth, DD | 1 |
Bousquet, P; Catelli, M; Feldman, J; Tibirica, E | 1 |
Chlopicki, S; Gryglewski, RJ; Kozlovski, VI | 1 |
Buckwalter, JB; Clifford, PS; Hamann, JJ; Taylor, JC | 1 |
Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
Bendhack, LM; Molin, JC | 1 |
Buckwalter, JB; Clifford, PS; de Craen, AJ; Hamann, JJ; Kamper, AM; Taylor, JC | 1 |
Borhani, AA; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Houshmand, G; Namiranian, K; Samini, M; Tavakoli, S | 1 |
Aronov, S; Ben-Abraham, R; Givati-Divshi, D; Katz, Y | 2 |
Garcez-do-Carmo, L; Santos, WC | 1 |
Bayati, A; Mattsson, H; Nielsen, MA | 1 |
Dehghani, M; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Jabehdar-Maralani, P; Sadeghipour, H; Shafaroodi, H; Tavakoli, S | 1 |
Abdel-Rahman, AA; Nassar, N | 1 |
Barinova, ME; Sulaieva, OM | 1 |
Hu, CP; Jiang, GL; Jiang, QT; Li, YJ; Peng, J; Zhang, YM | 1 |
Holzer, P; Painsipp, E; Shahbazian, A | 1 |
Abdel-Rahman, AA; Bender, TS | 1 |
Chen, MJ; Patel, NJ; Russo-Neustadt, AA | 1 |
Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
Clavreul, N; Isabelle, M; Ragonnet, C; Sansilvestri-Morel, P; Simonet, S; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
Govindasamy, C; Mustapha, Z; Nik Yusoff, NS; Sirajudeen, KN | 1 |
1 review(s) available for clonidine and ng-nitroarginine methyl ester
Article | Year |
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Nitric oxide synthase inhibitors. Preclinical studies of potential use for treatment of opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Clonidine; Depression, Chemical; Enzyme Inhibitors; Heart Rate; Indazoles; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opioid-Related Disorders; Ornithine; Substance Withdrawal Syndrome | 1995 |
38 other study(ies) available for clonidine and ng-nitroarginine methyl ester
Article | Year |
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Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arginine; Azepines; Clonidine; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred Strains | 1991 |
Influence of inhibition of endothelium-derived nitric oxide formation to effects of vasoconstrictor agents neuropeptide Y, clonidine, and ergonovine on coronary vascular resistance.
Topics: Animals; Arginine; Blood Pressure; Clonidine; Coronary Circulation; Dogs; Ergonovine; Female; Heart Rate; Male; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vascular Resistance; Vasoconstrictor Agents | 1994 |
Nitric oxide modulates sympathetic vasoconstriction and basal blood flow in normal and acutely inflamed rabbit knee joints.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arthritis; Blood Pressure; Brimonidine Tartrate; Clonidine; Electric Stimulation; Infusions, Intra-Arterial; Knee Joint; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Quinoxalines; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1993 |
Effect of NG-nitro-L-arginine methylester (L-NAME) on functional and biochemical alpha 1-adrenoceptor-mediated responses in rat blood vessels.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arteries; Clonidine; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenoxybenzamine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Tail; Vasoconstriction | 1996 |
Alpha-2 adrenoceptor agonists decrease cyclic guanosine 3',5'-monophosphate in the mouse brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Clonidine; Cyclic GMP; Imidazoles; Male; Medetomidine; Mice; NG-Nitroarginine Methyl Ester | 1996 |
Alpha 2-adrenoceptor activation may trigger the increased production of endothelium-derived nitric oxide in skeletal muscle during acute haemorrhage.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Epinephrine; Hemorrhage; Idazoxan; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Vasodilation | 1998 |
Nitric oxide modulates spinal antinociceptive effect of clonidine but not that of baclofen in the formalin test in rats.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Arginine; Baclofen; Clonidine; Enzyme Inhibitors; Formaldehyde; GABA Agonists; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement; Postural Balance; Rats; Rats, Wistar | 1999 |
[Influence of nitric oxide synthetase inhibitor on the blood pressure action of clonidine in rats].
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Clonidine; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1998 |
Gender differences in the endothelial regulation of alpha2-adrenoceptor-mediated contraction in the rat aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Castration; Clonidine; Endothelium, Vascular; Enzyme Inhibitors; Female; Gonadal Steroid Hormones; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Rats; Sex Factors | 1999 |
Blockade of nitric oxide formation impairs adrenergic-induced ACTH and corticosterone secretion.
Topics: Adrenergic Agonists; Adrenocorticotropic Hormone; Animals; Clonidine; Corticosterone; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Adrenergic | 1999 |
Actions of L-NAME and methylene blue on the hypotensive effects of clonidine and rilmenidine in the anesthetized rat.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxazoles; Rats; Rats, Wistar; Rilmenidine | 2000 |
Alpha(2)-adrenergic-mediated tubular NO production inhibits thick ascending limb chloride absorption.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminoquinolines; Animals; Biological Transport; Chlorides; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Loop of Henle; Male; Nephrons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2001 |
Central hypotensive action of clonidine requires nitric oxide.
Topics: Animals; Antihypertensive Agents; Biosensing Techniques; Blood Pressure; Brain; Clonidine; Electrochemistry; Enzyme Inhibitors; Heart Rate; In Vitro Techniques; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2001 |
The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hypnotics and Sedatives; Indazoles; Male; Methyldopa; Midazolam; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Sleep; Thiopental | 2001 |
The effects of simultaneous administration of alpha(2) -adrenergic agents with L-NAME or L-arginine on the development and expression of morphine dependence in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arginine; Clonidine; Enzyme Inhibitors; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Substance Withdrawal Syndrome; Yohimbine | 2002 |
Intrathecal clonidine decreases spinal nitric oxide release in a rat model of complete Freund's adjuvant induced inflammatory pain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Enzyme Inhibitors; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Spinal; Male; Myelitis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 2002 |
Effect of nitric oxide inhibition with L-NAME on the blood pressure and renal response to clonidine in conscious rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Creatinine; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sodium; Urodynamics | 2002 |
Protective effects of centrally acting sympathomodulatory drugs on myocardial ischemia induced by sympathetic overactivity in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Electrocardiography; Female; Glutamic Acid; Heart Rate; Hemodynamics; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Oxazoles; Propranolol; Rabbits; Rilmenidine; Sympathetic Nervous System | 2003 |
Clonidine-induced coronary vasodilatation in isolated guinea pig heart is not mediated by endothelial alpha2 adrenoceptors.
Topics: Animals; Clonidine; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Guinea Pigs; Heart; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phentolamine; Prazosin; Ranitidine; Receptors, Adrenergic, alpha-2; Receptors, Histamine H2; Vasoconstriction; Vasodilation; Yohimbine | 2003 |
Role of nitric oxide in exercise sympatholysis.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dogs; Enzyme Inhibitors; Hemodynamics; Hindlimb; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phenylephrine; Physical Exertion; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Rest; Sympathetic Nervous System; Vasoconstrictor Agents; Vasopressins | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
Clonidine induces rat aorta relaxation by nitric oxide-dependent and -independent mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Indomethacin; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Phenylephrine; Potassium Chloride; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasodilation | 2004 |
Role of nitric oxide and alpha-adrenergic receptor responsiveness in exercising skeletal muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dogs; Enzyme Inhibitors; Hemodynamics; Hindlimb; Muscle, Skeletal; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phenylephrine; Physical Exertion; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Rest; Sympathetic Nervous System; Vasoconstrictor Agents; Vasopressins | 2005 |
alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bilirubin; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Male; Mesenteric Arteries; Mesentery; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilation; Vasodilator Agents; Yohimbine | 2005 |
Involvement of nitric oxide in clonidine-induced spinal analgesia.
Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Clonidine; Injections, Spinal; Male; Methylene Blue; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pain | 2005 |
Cerebroventricular injection of clonidine causes analgesia mediated by a nitrogen pathway.
Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Cerebral Ventricles; Clonidine; Injections; Male; Methylene Blue; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pain; Random Allocation | 2005 |
L-NAME pre-treatment partially inhibits the agmatine-evoked depression of the electrically induced twitch contraction of isolated rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Agmatine; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Epididymis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Synaptic Transmission; Vas Deferens | 2006 |
Wistar Kyoto rats have impaired gastric accommodation compared to Sprague Dawley rats due to increased gastric vagal cholinergic tone.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Enzyme Inhibitors; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Vagus Nerve; Vasodilator Agents | 2006 |
Modulated hemodynamic response to clonidine in bile duct-ligated rats: the role of nitric oxide.
Topics: Animals; Antihypertensive Agents; Bile Ducts; Blood Pressure; Bradycardia; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Injections, Intravenous; Injections, Subcutaneous; Ligation; Male; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2006 |
Brainstem phosphorylated extracellular signal-regulated kinase 1/2-nitric-oxide synthase signaling mediates the adenosine A2A-dependent hypotensive action of clonidine in conscious aortic barodenervated rats.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Abdominal; Clonidine; Denervation; Hypotension; Imidazoline Receptors; Male; Medulla Oblongata; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Adrenergic, alpha-2 | 2008 |
[State of intracellular signaling systems in endothelial dysfunction].
Topics: Adrenergic alpha-Agonists; Adult; Aged; Arginine; Clonidine; Diabetic Foot; Endothelium, Vascular; Female; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Platelet Aggregation; Receptors, Adrenergic; Signal Transduction | 2007 |
Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Calcitonin Gene-Related Peptide; Cells, Cultured; Clonidine; Endothelial Cells; Gene Expression; Gene Expression Regulation; Humans; Kinetics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Yohimbine | 2009 |
Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Carbazoles; Carbolines; Clonidine; Colitis; Colon; Fasting; Female; Heart Rate; Indoles; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Differential central NOS-NO signaling underlies clonidine exacerbation of ethanol-evoked behavioral impairment.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Central Nervous System Depressants; Clonidine; Drug Synergism; Ethanol; Extracellular Signal-Regulated MAP Kinases; Locus Coeruleus; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phosphorylation; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Signal Transduction | 2010 |
Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Clonidine; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Female; Food; Hippocampus; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Physiological | 2010 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Chronic reduction of nitric oxide level in adult spontaneously hypertensive rats induces aortic stiffness similar to old spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Clonidine; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Stiffness | 2012 |
Effect of Clonidine (an antihypertensive drug) treatment on oxidative stress markers in the heart of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Biomarkers; Blood Pressure; Clonidine; Heart; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Protein Carbonylation; Rats; Rats, Inbred SHR; Thiobarbituric Acid Reactive Substances | 2013 |