clonidine and naltrexone

clonidine has been researched along with naltrexone in 144 studies

Research

Studies (144)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (29.86)	18.7374
1990's	35 (24.31)	18.2507
2000's	43 (29.86)	29.6817
2010's	22 (15.28)	24.3611
2020's	1 (0.69)	2.80

Authors

Authors	Studies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Rawson, RA; Resnick, RB; Washton, AM	1
Sharpe, LG	1
Senft, RA	1
Arts, KS; Fujimoto, JM	1
Caballero, L; Iruela, LM; Oliveros, SC	1
Fraser, AD	1
Aranow, JS; Kelsey, JE; Matthews, RT	1
de Jong, W; Tierney, SA; van Giersbergen, PL; Wiegant, VM	1
Harris, JC; Kehoe, P	1
Drummond, DC; Turkington, D	1
Fram, DH; Holden, R; Marmo, J	1
Kunos, G; Mosqueda-Garcia, R	1
Cancela, LM; Molina, VA; Volosin, M	1
Peachey, JE	1
Brewer, C	2
de Jong, W; Henneveld, H; van den Buuse, M	1
Eskay, R; Kunos, G; Mosqueda-Garcia, R; Palkovits, M; Zamir, N	1
Arendt, RM; Schulz, R; Vollmar, AM	1
Gossop, M	1
Chinn, C; Horita, A; Yabase, M	1
Bailey, C; Brewer, C; Rezae, H	1
Kleber, HD; Kosten, TR; Vining, E	1
Agren, H	1
Gaspari, J; Kleber, HD; Kosten, T; Riordan, CE; Topazian, M	1
Charney, DS; Heninger, GR; Kleber, HD	1
Katz, NL; Schlemmer, RF; Waller, DP	1
Holtzman, SG	1
Gold, MS; Pottash, AC; Washton, AM	2
Ginzburg, HM; Glass, WJ	1
Rawson, RA; Resnick, RB; Tennant, FS; Washton, AM	2
Extein, I; Gold, MS; Kleber, HD; Pottash, AL	1
Resnick, RB; Washton, AM	4
Cerdeño Impuesto, V	1
Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD	1
Kunos, G; Mosqueda Garcia, R; Ramirez-Gonzalez, MD; Tchakarov, L	1
Dackis, CA; Gold, MS; Washton, AM	1
Dackis, CA; Gold, MS	1
Kleber, HD; Kosten, TR	1
Borrell, J; Fuentes, JA; Naranjo, JR	1
Ginzburg, HM	1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH	1
Braverman, P; Charney, DS; Heninger, GR; Kleber, HD; Murburg, M; Redmond, DE; Riordan, CE; Sternberg, DE	1
Fossom, LH; Sparber, SB	1
Carroll, KM; Diagkogiannis, IA; O'Connor, PG; Rounsaville, BJ; Schottenfeld, RS; Waugh, ME	1
Brodsky, M; Inturrisi, CE; Rasmussen, K	1
Hansen, S	1
Fujimoto, JM; Rady, JJ	1
Axtell, S; Baker, D; Cerutti, D; Hackenberg, T; Thompson, T	1
Azatian, A; Joseph, H; Papiasvilli, A	1
Amico, MC; Morrone, LA; Romanelli, L; Valeri, P	1
Cutler, R; Fishbain, DA; Rosomoff, HL	1
Gold, MS	1
Greenwood, J; Seivewright, NA	1
Campbell, M; Cueva, JE; Hallin, A; Schopler, E	1
Miranda, HF; Naquira, D; Pinardi, G; Sierralta, F	1
Intengan, HD; Smyth, DD	1
Bristow, LJ; Hogg, JE; Hutson, PH	1
Burden, HW; Davis, MC; Hodson, CA	1
Huber, A; Ling, W; McCann, MJ; Miotto, K; Rawson, RA; Shoptaw, S	1
Cohen, H; Kotler, M; Rabinowitz, J; Tarrasch, R	1
Rumball, D; Williams, J	1
Carroll, KM; Kosten, TR; O'Connor, PG; Rounsaville, BJ; Schottenfeld, RS; Shi, JM	1
Deden, AL; Kerkhof, AJ; Roozen, HG; van den Brink, W; Vorsteveld, JP	1
Fujimoto, JM; Holmes, BB; Rady, JJ	1
Cohen, H; Kotler, M; Rabinowitz, J	1
Bertschy, G; Cucchia, AT; Ferrero, F; Monnat, M; Spagnoli, J	1
Gray, AM; Nevinson, MJ; Sewell, RD	1
Gerada, C; Kemp, K; Smith, P	1
Bammer, G; Bell, JR; Masterman, SC; Mattick, RP; Morris, A; Young, MR	1
Chiang, CT; Demuth, KL; Hoover, DR; Montoya, ID; Preston, KL; Umbricht, A	1
Aguilar, A; Alberti, I; Alguacil, LF; Caamaño, M; Fernández, B; Romero, EM; Viveros, MP	1
Brotchie, JM; Hill, MP	1
Bocchi, C; Delsignore, R; Fontanesi, B; Gerra, G; Rustichelli, P; Timpano, M; Zaimovic, A; Zambelli, U	1
Conte, G; De Risio, S; Pozzi, G	1
Gyires, K; Müllner, K; Rónai, AZ	1
Bearn, J; Buntwal, N; Gossop, M; Strang, J	1
Bisaga, A; Popik, P; Radomska, M	1
Krall, CM; McDougall, SA; Nazarian, A; Osburn, JR	1
Golding, M; Hatsukami, DK; Jamerson, BD; Kotlyar, M	1
Atias, S; Cohen, H; Rabinowitz, J	1
Alvarez, CE; Bascarán, MT; Bobes, J; Brewer, C; Carreño, JE; San Narciso, GI; Sánchez del Río, J	1
Bu, H; Chen, YL; Halls, TD; Jiang, X; Naidong, W; Shou, WZ	1
Ali, R; Gowing, L; McGregor, C; Thomas, P; White, JM	1
Chiao, F; Erice, S; Leverone, T; Ma, H; Pearce, S; Quon, R; Tang, J; Wender, RH; White, PF	1
Dehpour, AR; Demehri, S; Gaskari, SA; Mehr, SE; Namiranian, K; Rastegar, H; Roushanzamir, F; Shariftabrizi, A	1
Baraban, JM; Reti, IM	1
Ahmadi, J; Ahmadi, M; Ahmadi, N; Ashkani, H	1
Kleber, HD	1
Aksel'rod, BA; Chichenkov, TO; Kubarev, DA; Savchenkov, VA; Sivolap, I	1
Golden, SA; Sakhrani, DL	1
France, CP; Koek, W; McMahon, LR; Sell, SL	1
Borhani, AA; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Houshmand, G; Namiranian, K; Samini, M; Tavakoli, S	1
Besson, J; Broers, B; Dorogy, F; Favrat, B; Krenz, S; Muller, J; Zimmermann, G; Zullino, D; Zwahlen, A	1
Collins, ED; Heitler, NE; Kleber, HD; Whittington, RA	1
O'Connor, PG	1
Ali, R; Gowing, L; White, J	1
Miller, MM	1
Besson, J; Favrat, B	1
Contreras, JA	1
de Jong, CJ	1
Cubells, JF; Tang, YL; Zhao, C; Zhao, D	1
Dehghani, M; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Jabehdar-Maralani, P; Sadeghipour, H; Shafaroodi, H; Tavakoli, S	1
Doebrick, C; Kimmerling, A; Kosten, TR; Sinha, R	1
Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Spealman, RD; Valdez, GR	1
Hubbard, R; Mannelli, P; Murray, HW; Patkar, AA; Peindl, K; Wu, LT	1
Gyires, K; Zádori, Z	1
Amato, L; Davoli, M; Minozzi, S	1
Frishtick, R; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I; Weizman, R	1
Ali, R; Gowing, L; White, JM	2
Bramness, J; Gossop, M; Lobmaier, P; Waal, H	1
Ejtemaeimehr, Sh; Fatemeh, A; Mohammadi, A; Naghizadeh, MM; Zangeneh, FZ	1
Gorelick, DA; Mannelli, P; Patkar, AA; Peindl, K; Wu, LT	1
Bisaga, A; Kosten, T; Nunes, EV; O'Connor, PG; Sigmon, SC; Woody, G	1
Law, F; Melichar, J; O'Shea, J; Praveen, KT	1
Al-Hasani, R; Bruchas, MR; Foshage, AM; McCall, JG	1
Amato, L; Bellisario, C; Davoli, M; Minozzi, S	1
Bisaga, A; Drill, ES; Khan, NA; Mogali, S; Nunes, E; Pavlicova, M; Sullivan, MA	1
Drummond, PD; Hood, S; Vo, L	1
Ayanga, D; Kosten, TR; Shorter, D	1
Bisaga, A; Carpenter, KM; Choi, CJ; Dakwar, E; Levin, FR; Mariani, JJ; Mishlen, K; Nunes, EV; Pavlicova, M; Sullivan, M	1
Bigelow, GE; Dunn, KE; Strain, EC; Tompkins, DA	1
Alto, W; Gianutsos, P; Mancl, L; Plawman, A; Rudolf, G; Rudolf, V; Walsh, J	1
Gupta, T; Jain, S; Nebhinani, N; Singhai, K; Suthar, N	1
Achenbach, C; Akanbi, MO; Bilaver, LA; Carroll, AJ; Hitsman, B; Jordan, N; McHugh, MC; Murphy, R; O'Dwyer, LC	1
Barnett, BS; Suzuki, J; Ward, HB	1
Banks, ML; Blake, S; Bremer, PT; Faunce, KE; Hwang, CS; Janda, KD; Natori, Y; Townsend, EA; Zhou, B	1
Fogelman, N; Hermes, G; Hyman, SM; Kosten, TR; Sinha, R	1
Chan, MH; Chen, HH; Chen, LC	1

Reviews

27 review(s) available for clonidine and naltrexone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Clonidine-naltrexone: a new technic for the detoxification of opiate addicts]. Medicina clinica, 1990, Nov-10, Volume: 95, Issue:16 Topics: Clonidine; Drug Therapy, Combination; Humans; Methadone; Naltrexone; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome	1990
Clinical toxicology of drugs used in the treatment of opiate dependency. Clinics in laboratory medicine, 1990, Volume: 10, Issue:2 Topics: Buprenorphine; Clonidine; Humans; Methadone; Methadyl Acetate; Naltrexone; Opioid-Related Disorders	1990
Clonidine and the treatment of the opiate withdrawal syndrome. Drug and alcohol dependence, 1988, Volume: 21, Issue:3 Topics: Clonidine; Humans; Hypotension; Methadone; Naltrexone; Narcotics; Substance Withdrawal Syndrome	1988
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory. Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327 Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome	1986
[Narcotic withdrawal syndrome. Therapeutic methods]. Revista clinica espanola, 1982, Oct-15, Volume: 167, Issue:1 Topics: Acupuncture Therapy; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Analgesia; Brain; Central Nervous System Agents; Clonidine; Endorphins; Humans; Methadone; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders	1982
The sequential use of clonidine and naltrexone in the treatment of opiate addicts. Advances in alcohol & substance abuse, 1984,Spring, Volume: 3, Issue:3 Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1984
New insights and treatments: opiate withdrawal and cocaine addiction. Clinical therapeutics, 1984, Volume: 7, Issue:1 Topics: Brain Chemistry; Clonidine; Cocaine; Dopamine; Humans; Methadone; Naltrexone; Norepinephrine; Substance Withdrawal Syndrome; Substance-Related Disorders	1984
Opiate detoxification protocols. A clinical manual. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1 Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Codeine; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Psychiatric Status Rating Scales; Receptors, Opioid; Substance Withdrawal Syndrome	1993
Opiate addiction and the locus coeruleus. The clinical utility of clonidine, naltrexone, methadone, and buprenorphine. The Psychiatric clinics of North America, 1993, Volume: 16, Issue:1 Topics: Animals; Buprenorphine; Clonidine; Humans; Locus Coeruleus; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1993
What is important in drug misuse treatment? Lancet (London, England), 1996, Feb-10, Volume: 347, Issue:8998 Topics: Buprenorphine; Clonidine; Humans; Methadone; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; United Kingdom	1996
Treatment of autistic disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 1996, Volume: 35, Issue:2 Topics: Antipsychotic Agents; Autistic Disorder; Behavior Therapy; Clomipramine; Clonidine; Fenfluramine; Humans; Naltrexone; Rehabilitation, Vocational; Selective Serotonin Reuptake Inhibitors; Speech Therapy	1996
Compliance to naltrexone treatment after ultra-rapid opiate detoxification: an open label naturalistic study. Drug and alcohol dependence, 1997, Aug-25, Volume: 47, Issue:2 Topics: Anesthesia, General; Clonidine; Follow-Up Studies; Humans; Israel; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome	1997
An addict who wants to detoxify. The Practitioner, 1998, Volume: 242, Issue:1592 Topics: Acquired Immunodeficiency Syndrome; Adult; Clonidine; Heroin Dependence; Humans; Jaundice; Male; Naltrexone; Needle Sharing; Serologic Tests	1998
[Contemporary methods in pharmacotherapy in the opiate dependent treatment]. Przeglad lekarski, 2000, Volume: 57, Issue:10 Topics: Adrenergic alpha-Agonists; Buprenorphine; Clonidine; Heroin Dependence; Humans; Inactivation, Metabolic; Methadone; Naltrexone; Narcotic Antagonists; Narcotics	2000
Effect of nonnicotine pharmacotherapy on smoking behavior. Pharmacotherapy, 2001, Volume: 21, Issue:12 Topics: Amphetamines; Bupropion; Clonidine; Doxepin; Humans; Naltrexone; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Smoking Cessation	2001
Pharmacologic treatments for heroin and cocaine dependence. The American journal on addictions, 2003, Volume: 12, Issue:s2 Topics: Buprenorphine; Clonidine; Cocaine-Related Disorders; Comorbidity; Heroin Dependence; Humans; Mental Disorders; Methadone; Methadyl Acetate; Naltrexone; Narcotic Antagonists; Narcotics	2003
Opioid antagonists with minimal sedation for opioid withdrawal. The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1 Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic	2006
Opiate addiction in China: current situation and treatments. Addiction (Abingdon, England), 2006, Volume: 101, Issue:5 Topics: Buprenorphine; China; Clonidine; Drugs, Chinese Herbal; HIV Infections; Humans; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Abuse, Intravenous; Substance Withdrawal Syndrome; Sympatholytics	2006
Detoxification treatments for opiate dependent adolescents. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Adolescent; Buprenorphine; Clonidine; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders	2009
Opioid antagonists with minimal sedation for opioid withdrawal. The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4 Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome	2009
The pharmacological treatment of opioid addiction--a clinical perspective. European journal of clinical pharmacology, 2010, Volume: 66, Issue:6 Topics: Adrenergic Agonists; Analgesics, Opioid; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Social Support; Substance Withdrawal Syndrome	2010
Opioid detoxification and naltrexone induction strategies: recommendations for clinical practice. The American journal of drug and alcohol abuse, 2012, Volume: 38, Issue:3 Topics: Adrenergic alpha-2 Receptor Agonists; Buprenorphine; Clinical Protocols; Clonidine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome	2012
Detoxification treatments for opiate dependent adolescents. The Cochrane database of systematic reviews, 2014, Apr-29, Issue:4 Topics: Adolescent; Buprenorphine; Clonidine; Humans; Maintenance Chemotherapy; Naloxone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Dropouts; Randomized Controlled Trials as Topic	2014
Update on pharmacotherapy for treatment of opioid use disorder. Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:17 Topics: Adrenergic alpha-2 Receptor Agonists; Buprenorphine; Clonidine; Combined Modality Therapy; Humans; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome	2016
Opioid antagonists with minimal sedation for opioid withdrawal. The Cochrane database of systematic reviews, 2017, 05-29, Volume: 5 Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Non-Randomized Controlled Trials as Topic; Opioid-Related Disorders; Prospective Studies; Randomized Controlled Trials as Topic; Severity of Illness Index; Substance Withdrawal Syndrome	2017
The efficacy of smoking cessation interventions in low- and middle-income countries: a systematic review and meta-analysis. Addiction (Abingdon, England), 2019, Volume: 114, Issue:4 Topics: Adult; Behavior Therapy; Bupropion; Cigarette Smoking; Clonidine; Counseling; Developing Countries; Humans; Mobile Applications; Naltrexone; Nortriptyline; Randomized Controlled Trials as Topic; Smoking Cessation; Smoking Cessation Agents; Tobacco Use Cessation Devices; Varenicline	2019

Trials

25 trial(s) available for clonidine and naltrexone

Article	Year
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory. Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327 Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome	1986
The role of the National Institute on Drug Abuse in the development of naltrexone. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:9 Pt 2 Topics: Aftercare; Animals; Carcinogens; Clinical Trials as Topic; Clonidine; Drug Administration Schedule; Drug and Narcotic Control; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Motivation; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Compliance; Rats; United States; United States Substance Abuse and Mental Health Services Administration	1984
Clonidine versus methadone for opiate detoxification. Lancet (London, England), 1980, Dec-13, Volume: 2, Issue:8207 Topics: Clinical Trials as Topic; Clonidine; Humans; Inactivation, Metabolic; Methadone; Naltrexone; Opioid-Related Disorders	1980
Clonidine and naltrexone. A safe, effective, and rapid treatment of abrupt withdrawal from methadone therapy. Archives of general psychiatry, 1982, Volume: 39, Issue:11 Topics: Adult; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1982
Primary care-based ambulatory opioid detoxification: the results of a clinical trial. Journal of general internal medicine, 1995, Volume: 10, Issue:5 Topics: Adolescent; Adult; Ambulatory Care; Chi-Square Distribution; Clonidine; Cohort Studies; Drug Administration Schedule; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Male; Middle Aged; Naltrexone; Opioid-Related Disorders; Pilot Projects; Primary Health Care; Prospective Studies; Treatment Outcome	1995
Opioid antagonist effects on self-injury in adults with mental retardation: response form and location as determinants of medication effects. American journal of mental retardation : AJMR, 1994, Volume: 99, Issue:1 Topics: Adult; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Liver Function Tests; Male; Naltrexone; Receptors, Opioid; Self-Injurious Behavior; Social Environment	1994
Three methods of opioid detoxification in a primary care setting. A randomized trial. Annals of internal medicine, 1997, Oct-01, Volume: 127, Issue:7 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Buprenorphine; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heroin; Heroin Dependence; Humans; Inactivation, Metabolic; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Primary Health Care; Substance Withdrawal Syndrome	1997
A pilot study of naltrexone-accelerated detoxification in opioid dependence. The Medical journal of Australia, 1999, Jul-05, Volume: 171, Issue:1 Topics: Adolescent; Adult; Analgesics; Anti-Anxiety Agents; Clonidine; Conscious Sedation; Female; Flunitrazepam; Heroin; Heroin Dependence; Hormones; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Octreotide; Pilot Projects; Substance Withdrawal Syndrome; Time Factors	1999
Naltrexone shortened opioid detoxification with buprenorphine. Drug and alcohol dependence, 1999, Oct-01, Volume: 56, Issue:3 Topics: Adult; Analgesics; Area Under Curve; Buprenorphine; Clonidine; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heroin; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome	1999
Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance. Journal of substance abuse treatment, 2000, Volume: 18, Issue:2 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; GABA Agents; Heroin Dependence; Humans; Inactivation, Metabolic; Ketoprofen; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxazepam; Patient Compliance; Substance Withdrawal Syndrome; Treatment Outcome	2000
Combined use of trazodone-naltrexone versus clonidine-naltrexone in rapid withdrawal from methadone treatment. A comparative inpatient study. Drug and alcohol dependence, 2000, Jun-01, Volume: 59, Issue:3 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analysis of Variance; Clonidine; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Substance Withdrawal Syndrome; Trazodone	2000
Naltrexone and lofexidine combination treatment compared with conventional lofexidine treatment for in-patient opiate detoxification. Drug and alcohol dependence, 2000, May-01, Volume: 59, Issue:2 Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Neurologic Examination; Opioid-Related Disorders; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome	2000
24-Hour opiate detoxification and antagonist induction at home--the 'Asturian method': a report on 1368 procedures. Addiction biology, 2002, Volume: 7, Issue:2 Topics: Administration, Oral; Adult; Aftercare; Anti-Anxiety Agents; Benzodiazepines; Clonidine; Drug Implants; Female; Follow-Up Studies; Heroin Dependence; Home Care Services, Hospital-Based; Humans; Male; Methadone; Naltrexone; Octreotide; Opioid-Related Disorders; Patient Admission; Substance Withdrawal Syndrome; Time Factors	2002
A comparison of antagonist-precipitated withdrawal under anesthesia to standard inpatient withdrawal as a precursor to maintenance naltrexone treatment in heroin users: outcomes at 6 and 12 months. Drug and alcohol dependence, 2002, Sep-01, Volume: 68, Issue:1 Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, General; Clonidine; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Risk Factors; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome	2002
Twenty-four week maintenance treatment of cigarette smoking with nicotine gum, clonidine and naltrexone. Journal of substance abuse treatment, 2003, Volume: 24, Issue:3 Topics: Adult; Antihypertensive Agents; Chewing Gum; Clonidine; Double-Blind Method; Humans; Iran; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nicotine; Prospective Studies; Smoking; Smoking Cessation; Smoking Prevention; Time Factors	2003
Opioid antagonist detoxification under anaesthesia versus traditional clonidine detoxification combined with an additional week of psychosocial support: a randomised clinical trial. Drug and alcohol dependence, 2006, Feb-01, Volume: 81, Issue:2 Topics: Adult; Algorithms; Analgesics; Anesthesia, General; Clonidine; Drug Administration Schedule; Female; Heroin Dependence; Hospitals, Psychiatric; Hospitals, Teaching; Humans; Inactivation, Metabolic; Male; Naltrexone; Narcotic Antagonists; Prospective Studies; Recurrence; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome	2006
Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial. JAMA, 2005, Aug-24, Volume: 294, Issue:8 Topics: Adult; Anesthesia, General; Buprenorphine; Clonidine; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome	2005
Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology, 2007, Volume: 190, Issue:4 Topics: Adult; Behavior, Addictive; Clonidine; Cues; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Secondary Prevention; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome	2007
Effectiveness of low-dose naltrexone in the post-detoxification treatment of opioid dependence. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:5 Topics: Adrenergic alpha-Agonists; Adult; Analysis of Variance; Clonidine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Psychotherapy; Substance Withdrawal Syndrome; Treatment Refusal	2007
The combination very low-dose naltrexone-clonidine in the management of opioid withdrawal. The American journal of drug and alcohol abuse, 2012, Volume: 38, Issue:3 Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Disease Management; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome	2012
Baseline characteristics of patients predicting suitability for rapid naltrexone induction. The American journal on addictions, 2015, Volume: 24, Issue:3 Topics: Administration, Oral; Adult; Buprenorphine; Clonidine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Injections, Intramuscular; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Selection; Prognosis	2015
Involvement of Opioid Receptors and α The journal of pain, 2016, Volume: 17, Issue:11 Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Blood Pressure; Central Nervous System Sensitization; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Administration Routes; Electric Stimulation; Female; Healthy Volunteers; Heart Rate; Humans; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Psychophysics; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine; Young Adult	2016
Long-Acting Injectable Naltrexone Induction: A Randomized Trial of Outpatient Opioid Detoxification With Naltrexone Versus Buprenorphine. The American journal of psychiatry, 2017, 05-01, Volume: 174, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Behavior Therapy; Buprenorphine; Clonidine; Combined Modality Therapy; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Naltrexone; Opioid-Related Disorders; Remission Induction; Secondary Prevention; Young Adult	2017
Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial. JAMA psychiatry, 2017, 09-01, Volume: 74, Issue:9 Topics: Adult; Analgesics; Analgesics, Opioid; Buprenorphine; Clonidine; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol; Treatment Outcome; Young Adult	2017
Lofexidine in Combination With Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A Pilot Randomized, Double-Blind, Placebo-Controlled Study. The American journal on addictions, 2019, Volume: 28, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Chemoprevention; Clonidine; Craving; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Male; Medication Adherence; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Pilot Projects; Recurrence; Secondary Prevention; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2019

Other Studies

93 other study(ies) available for clonidine and naltrexone

Article	Year
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Clonidine hydrochloride: a nonopiate treatment for opiate withdrawal. NIDA research monograph, 1979, Volume: 27 Topics: Clonidine; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1979
Separate neural mechanisms mediate sufentanil-induced pupillary responses in the cat. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3 Topics: Analgesics, Opioid; Animals; Cats; Clonidine; Drug Interactions; Fentanyl; Male; Morphine; Mydriasis; Naltrexone; Pupil; Receptors, Opioid; Receptors, Opioid, mu; Sufentanil	1991
Experience with clonidine-naltrexone for rapid opiate detoxification. Journal of substance abuse treatment, 1991, Volume: 8, Issue:4 Topics: Adult; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Middle Aged; Naltrexone; Neurologic Examination; Substance Withdrawal Syndrome	1991
Clonidine, administered intracerebroventricularly in mice, produces an anti-analgesic effect which may be mediated spinally by dynorphin A (1-17). Neuropharmacology, 1990, Volume: 29, Issue:4 Topics: Analgesics; Animals; Clonidine; Dynorphins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Reaction Time	1990
Context-specific morphine withdrawal in rats: duration and effects of clonidine. Behavioral neuroscience, 1990, Volume: 104, Issue:5 Topics: Animals; Arousal; Association Learning; Clonidine; Male; Morphine; Morphine Dependence; Motor Activity; Naltrexone; Rats; Social Environment; Substance Withdrawal Syndrome; Weight Loss	1990
Possible involvement of brain opioid peptides in clonidine-induced hypotension in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:1 Topics: Animals; Blood Pressure; Brain; Clonidine; Endorphins; Heart Rate; Hypertension; Male; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Opioid; Sodium Glutamate	1989
Ontogeny of noradrenergic effects on ultrasonic vocalizations in rat pups. Behavioral neuroscience, 1989, Volume: 103, Issue:5 Topics: Aging; Animals; Animals, Newborn; Arousal; Brain; Clonidine; Emotions; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Social Isolation; Ultrasonics; Vocalization, Animal; Yohimbine	1989
Naltrexone and clonidine in heroin withdrawal treatment. The British journal of psychiatry : the journal of mental science, 1989, Volume: 154 Topics: Clonidine; Heroin; Humans; Naltrexone; Substance Withdrawal Syndrome	1989
Naltrexone treatment--the problem of patient acceptance. Journal of substance abuse treatment, 1989, Volume: 6, Issue:2 Topics: Adult; Clonidine; Female; Follow-Up Studies; Humans; Male; Methadone; Naltrexone; Opioid-Related Disorders; Patient Acceptance of Health Care	1989
Opiate receptors and the endorphin-mediated cardiovascular effects of clonidine in rats: evidence for hypertension-induced mu-subtype to delta-subtype changes. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:23 Topics: Animals; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Heart Rate; Hypertension; Male; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Chronic stress attenuation of alpha 2-adrenoceptor reactivity is reversed by naltrexone. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1 Topics: Animals; Clonidine; Male; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stress, Physiological	1988
The role of drugs in the treatment of opioid addicts. The Medical journal of Australia, 1986, Oct-20, Volume: 145, Issue:8 Topics: Alcoholism; Anxiety; Clonidine; Dextropropoxyphene; Heroin; Humans; Inactivation, Metabolic; Kinetics; Methadone; Mood Disorders; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders	1986
Blood pressure monitoring at home for rapid opioid withdrawal with clonidine and naltrexone. Lancet (London, England), 1987, Mar-14, Volume: 1, Issue:8533 Topics: Administration, Oral; Adult; Blood Pressure Determination; Clonidine; Drug Therapy, Combination; Female; Heroin; Home Nursing; Humans; Monitoring, Physiologic; Naltrexone; Substance Withdrawal Syndrome; Telephone	1987
Naltrexone and the behavioural action of clonidine in normotensive and spontaneously hypertensive rats. The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:4 Topics: Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY	1988
Opioid-mediated cardiovascular effects of clonidine in spontaneously hypertensive rats: elimination by neonatal treatment with monosodium glutamate. Endocrinology, 1986, Volume: 118, Issue:5 Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Glutamates; Heart Rate; Hemodynamics; Hypertension; Medulla Oblongata; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Glutamate	1986
The effect of opioids on rat plasma atrial natriuretic peptide. European journal of pharmacology, 1987, Nov-17, Volume: 143, Issue:3 Topics: Amino Acids; Animals; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Male; Naltrexone; Narcotics; Radioimmunoassay; Rats; Rats, Inbred Strains	1987
Opiate withdrawal: inpatient versus outpatient programmes. British medical journal (Clinical research ed.), 1986, Aug-09, Volume: 293, Issue:6543 Topics: Clonidine; Heroin; Hospitalization; Humans; Naltrexone; Substance Withdrawal Syndrome	1986
Clonidine activates a cholinergic hippocampal theta rhythm in the rat. Proceedings of the Western Pharmacology Society, 1988, Volume: 31 Topics: Animals; Clonidine; Electroencephalography; Hippocampus; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Theta Rhythm; Yohimbine	1988
Opioid withdrawal and naltrexone induction in 48-72 hours with minimal drop-out, using a modification of the naltrexone-clonidine technique. The British journal of psychiatry : the journal of mental science, 1988, Volume: 153 Topics: Adolescent; Adult; Clonidine; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Narcotics; Substance Withdrawal Syndrome; Time Factors	1988
Clinical utility of rapid clonidine-naltrexone detoxification for opioid abusers. British journal of addiction, 1988, Volume: 83, Issue:5 Topics: Adult; Clinical Protocols; Clonidine; Drug Therapy, Combination; Female; Heroin; Humans; Male; Naltrexone; Substance-Related Disorders	1988
Clonidine and naltrexone in the outpatient treatment of heroin withdrawal. The American journal of drug and alcohol abuse, 1987, Volume: 13, Issue:1-2 Topics: Adult; Ambulatory Care; Clonidine; Drug Therapy, Combination; Female; Heroin; Humans; Male; Naltrexone; Substance Withdrawal Syndrome	1987
The combined use of clonidine and naltrexone as a rapid, safe, and effective treatment of abrupt withdrawal from methadone. The American journal of psychiatry, 1986, Volume: 143, Issue:7 Topics: Adult; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Methadone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders	1986
Stereospecific reduction by narcotic antagonists of clonidine-induced food intake. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:4 Topics: Animals; Benzomorphans; Clonidine; Dose-Response Relationship, Drug; Feeding Behavior; Male; Naltrexone; Narcotic Antagonists; Rabbits; Stereoisomerism	1985
Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1 Topics: Animals; Body Weight; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Stereoisomerism; Substance Withdrawal Syndrome	1985
Naltrexone in addicted business executives and physicians. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:9 Pt 2 Topics: Administrative Personnel; Adult; Aftercare; Ambulatory Care; Clonidine; Commerce; Female; Hospitalization; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Compliance; Physician Impairment	1984
Clonidine hydrochloride detoxification from methadone treatment--the value of naltrexone aftercare. Advances in alcohol & substance abuse, 1984,Spring, Volume: 3, Issue:3 Topics: Adult; Aftercare; Attitude to Health; Clonidine; Female; Follow-Up Studies; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1984
Clonidine and opiate withdrawal. Lancet (London, England), 1980, Nov-15, Volume: 2, Issue:8203 Topics: Clonidine; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1980
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine	1980
beta-endorphin acting on the brainstem is involved in the antihypertensive action of clonidine and alpha-methyldopa in rats. Circulation research, 1983, Volume: 53, Issue:2 Topics: Animals; beta-Endorphin; Blood Pressure; Clonidine; Desoxycorticosterone; Endorphins; Heart Rate; Hypertension; Hypertension, Renal; Immune Sera; Male; Methyldopa; Naltrexone; Rats; Rats, Inbred Strains; Rats, Mutant Strains	1983
Recent advances in opiate detoxification: clonidine and lofexidine. NIDA research monograph, 1983, Volume: 43 Topics: Clonidine; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1983
Naltrexone in addicted physicians and business executives. NIDA research monograph, 1984, Volume: 55 Topics: Clonidine; Commerce; Humans; Naltrexone; Opioid-Related Disorders; Physicians; Socioeconomic Factors; Time Factors	1984
Naltrexone induction: psychologic and pharmacologic strategies. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:9 Pt 2 Topics: Ambulatory Care; Behavior Therapy; Clonidine; Counseling; Drug Administration Schedule; Drug Therapy, Combination; Family Therapy; Hospitalization; Humans; Illicit Drugs; Injections, Intramuscular; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Dropouts; Research Design	1984
Opioid involvement in hypertension induced by short-term isolation. Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:10-11 Topics: Adrenalectomy; Animals; Clonidine; Endorphins; Humans; Hypertension; Male; Naloxone; Naltrexone; Psychophysiologic Disorders; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Social Isolation	1984
Naltrexone and clonidine: alternatives to methadone. American family physician, 1983, Volume: 28, Issue:5 Topics: Clonidine; Humans; Naloxone; Naltrexone; Opioid-Related Disorders	1983
Clonidine hydrochloride detoxification from methadone treatments: the value of naltrexone aftercare. NIDA research monograph, 1981, Volume: 34 Topics: Adolescent; Clonidine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Opium; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1981
Narcotic discrimination in pigeons. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity	1980
Outpatient opiate detoxification with clonidine. The Journal of clinical psychiatry, 1982, Volume: 43, Issue:6 Pt 2 Topics: Ambulatory Care; Clonidine; Double-Blind Method; Drug Therapy, Combination; Heroin Dependence; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1982
Potentiation by naltrexone of d-amphetamine-induced behavioral suppression and its reversal by clonidine. Life sciences, 1982, Dec-20, Volume: 31, Issue:25 Topics: Animals; Clonidine; Conditioning, Operant; Dextroamphetamine; Drug Interactions; Male; Naloxone; Naltrexone; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine	1982
The clinical use of clonidine in outpatient detoxification from opiates. Progress in clinical and biological research, 1981, Volume: 71 Topics: Clonidine; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Self Administration; Substance Withdrawal Syndrome	1981
NMDA antagonists and clonidine block c-fos expression during morphine withdrawal. Synapse (New York, N.Y.), 1995, Volume: 20, Issue:1 Topics: Animals; Clonidine; Dizocilpine Maleate; Gene Expression; Genes, fos; In Vitro Techniques; Isoquinolines; Male; Morphine; Naltrexone; Neural Pathways; Nucleic Acid Hybridization; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA Probes; RNA, Messenger; Substance Withdrawal Syndrome	1995
Effect of clonidine on the responsiveness of infant rats to maternal stimuli. Psychopharmacology, 1993, Volume: 111, Issue:1 Topics: Animals; Animals, Newborn; Behavior, Animal; Choice Behavior; Clonidine; Dopamine Antagonists; Female; Maternal Behavior; Motor Activity; Naltrexone; Propranolol; Raclopride; Rats; Rats, Wistar; Salicylamides; Smell; Sucking Behavior; Sucrose; Vocalization, Animal	1993
Dynorphin A(1-17) mediates midazolam antagonism of morphine antinociception in mice. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2 Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Dynorphins; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Midazolam; Morphine; Naloxone; Naltrexone; Pain Measurement; Reaction Time; Spinal Cord	1993
A study of the use of clonidine and naltrexone in the treatment of opioid addiction in the former USSR. Journal of addictive diseases, 1994, Volume: 13, Issue:1 Topics: Adult; Clonidine; Cross-Cultural Comparison; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Naltrexone; Neurologic Examination; Opioid-Related Disorders; Patient Dropouts; Recurrence; Treatment Outcome; USSR	1994
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome	1993
alpha-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception. British journal of pharmacology, 1996, Volume: 119, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Prazosin; Receptors, Opioid; Yohimbine	1996
Clonidine-induced increase in osmolar clearance and free water clearance via activation of two distinct alpha 2-adrenoceptor sites. British journal of pharmacology, 1996, Volume: 119, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Male; Naltrexone; Osmolar Concentration; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Water	1996
Competitive and glycine/NMDA receptor antagonists attenuate withdrawal-induced behaviours and increased hippocampal acetylcholine efflux in morphine-dependent rats. Neuropharmacology, 1997, Volume: 36, Issue:2 Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Binding, Competitive; Clonidine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Microdialysis; Morphine Dependence; Naltrexone; Narcotic Antagonists; Pipecolic Acids; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome	1997
Effect of prior nicotine treatment on drug induced changes in serum LH concentrations in rats. Life sciences, 1997, Volume: 60, Issue:25 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Gonadotropin-Releasing Hormone; Haloperidol; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical	1997
Outpatient non-opioid detoxification for opioid withdrawal. Who is likely to benefit? The American journal on addictions, 1997,Summer, Volume: 6, Issue:3 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Ambulatory Care Facilities; Clonidine; Female; GABA Modulators; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Oxazepam; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome	1997
Rapid opiate detoxification. Assessment is needed to exclude certain patients before detoxification. BMJ (Clinical research ed.), 1997, Sep-13, Volume: 315, Issue:7109 Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Naltrexone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Substance-Related Disorders	1997
[Detoxication in opiate addiction and prevention of recurrence: administration of naltrexone and cognitive behavior therapy]. Nederlands tijdschrift voor geneeskunde, 1997, Dec-06, Volume: 141, Issue:49 Topics: Adrenergic alpha-Agonists; Adult; Behavior Therapy; Clonidine; Combined Modality Therapy; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Pilot Projects; Substance Abuse Treatment Centers	1997
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17). Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1 Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine	1998
Outcomes of ultrarapid opiate detoxification combined with naltrexone maintenance and counseling. Psychiatric services (Washington, D.C.), 1998, Volume: 49, Issue:6 Topics: Adult; Anesthesia, General; Clonidine; Combined Modality Therapy; Counseling; Follow-Up Studies; Humans; Intensive Care Units; Israel; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Recurrence; Sympatholytics; Time Factors; Treatment Outcome	1998
Ultra-rapid opiate detoxification using deep sedation with oral midazolam: short and long-term results. Drug and alcohol dependence, 1998, Nov-01, Volume: 52, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Anesthesia, General; Clonidine; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Heroin Dependence; Humans; Hypnotics and Sedatives; Length of Stay; Male; Methadone; Midazolam; Naltrexone; Narcotic Antagonists; Neurologic Examination; Ondansetron; Substance Withdrawal Syndrome; Treatment Outcome	1998
The involvement of opioidergic and noradrenergic mechanisms in nefopam antinociception. European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3 Topics: Abdominal Pain; Acetic Acid; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nefopam; Pain Measurement; Receptors, Adrenergic; Receptors, Opioid	1999
Preweanling naltrindole administration differentially affects clonidine induced antinociception and plasma adrenaline levels in male and female neonatal rats. British journal of pharmacology, 1999, Volume: 128, Issue:5 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Animals, Newborn; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Sex Characteristics	1999
The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat. British journal of pharmacology, 1999, Volume: 128, Issue:7 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzofurans; Biogenic Monoamines; Clonidine; Disease Models, Animal; Drug Combinations; Drug Synergism; Locomotion; Male; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Prazosin; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reserpine; Yohimbine	1999
Functional evidence that gastroprotection can be induced by activation of central alpha(2B)-adrenoceptor subtypes in the rat. European journal of pharmacology, 2000, May-19, Volume: 396, Issue:2-3 Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Enkephalin, Leucine-2-Alanine; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2	2000
Ultrasonic vocalizations of preweanling rats: involvement of both alpha(2)-adrenoceptor and kappa-opioid receptor systems. European journal of pharmacology, 2001, Volume: 415, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Animals, Suckling; Clonidine; Female; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, kappa; Vocalization, Animal; Yohimbine	2001
Outcomes of naltrexone maintenance following ultra rapid opiate detoxification versus intensive inpatient detoxification. The American journal on addictions, 2002,Winter, Volume: 11, Issue:1 Topics: Adult; Analgesics; Clonidine; Humans; Inactivation, Metabolic; Israel; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Recurrence; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome	2002
Simultaneous development of six LC-MS-MS methods for the determination of multiple analytes in human plasma. Journal of pharmaceutical and biomedical analysis, 2002, Jun-15, Volume: 28, Issue:6 Topics: Albuterol; Chromatography, Liquid; Clonidine; Fentanyl; Humans; Loratadine; Mass Spectrometry; Naltrexone; Pharmaceutical Preparations; Ritonavir; Technology, Pharmaceutical	2002
The effect of clonidine on gastrointestinal side effects associated with ultra-rapid opioid detoxification. Anesthesia and analgesia, 2003, Volume: 96, Issue:5 Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Diarrhea; Female; Gastrointestinal Diseases; Humans; Hypnotics and Sedatives; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Nausea; Opioid-Related Disorders; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome; Vomiting	2003
Alpha-2-adrenoceptor hyporesponsiveness in isolated tissues of cholestatic animals: involvement of opioid and nitric oxide systems. Life sciences, 2003, May-30, Volume: 73, Issue:2 Topics: Animals; Catecholamines; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Mice; Naltrexone; Nitric Oxide; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine	2003
Opiate withdrawal induces Narp in the extended amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:9 Topics: Amygdala; Analgesics; Animals; C-Reactive Protein; Cell Count; Clonidine; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Septal Nuclei; Substance Withdrawal Syndrome	2003
[Detoxification in withdrawal state in methadone maintenance patients]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11 Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Data Interpretation, Statistical; Heroin Dependence; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome	2003
Unexpected delirium during Rapid Opioid Detoxification (ROD). Journal of addictive diseases, 2004, Volume: 23, Issue:1 Topics: Adult; Alcohol Withdrawal Delirium; Clonidine; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Inactivation, Metabolic; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome	2004
Monoaminergic drugs and directly observable signs of LAAM withdrawal in rhesus monkeys. Behavioural pharmacology, 2005, Volume: 16, Issue:1 Topics: Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Clonidine; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Methadyl Acetate; Muscle Rigidity; Naltrexone; Narcotic Antagonists; Respiratory Mechanics; Salivation; Substance Withdrawal Syndrome	2005
alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids. European journal of pharmacology, 2005, May-09, Volume: 514, Issue:2-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bilirubin; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Male; Mesenteric Arteries; Mesentery; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Vasodilation; Vasodilator Agents; Yohimbine	2005
Methods of detoxification and their role in treating patients with opioid dependence. JAMA, 2005, Aug-24, Volume: 294, Issue:8 Topics: Anesthesia, General; Buprenorphine; Clonidine; Female; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Failure	2005
Heroin detoxification. JAMA, 2006, Feb-22, Volume: 295, Issue:8 Topics: Anesthesia, General; Buprenorphine; Clonidine; Drug Therapy, Combination; Heroin Dependence; Humans; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome	2006
Heroin detoxification. JAMA, 2006, Feb-22, Volume: 295, Issue:8 Topics: Anesthesia, General; Buprenorphine; Clonidine; Drug Therapy, Combination; Heroin Dependence; Humans; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome	2006
Detoxification and treating opioid dependence. JAMA, 2006, Feb-22, Volume: 295, Issue:8 Topics: Anesthesia, General; Buprenorphine; Clonidine; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome	2006
Detoxification and treating opioid dependence. JAMA, 2006, Feb-22, Volume: 295, Issue:8 Topics: Anesthesia, General; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome	2006
Modulated hemodynamic response to clonidine in bile duct-ligated rats: the role of nitric oxide. European journal of pharmacology, 2006, Aug-07, Volume: 542, Issue:1-3 Topics: Animals; Antihypertensive Agents; Bile Ducts; Blood Pressure; Bradycardia; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Injections, Intravenous; Injections, Subcutaneous; Ligation; Male; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley	2006
Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2 Topics: Animals; Behavior, Addictive; Benzofurans; Clonidine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Male; Naltrexone; Norepinephrine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri; Self Administration; Stress, Psychological	2007
[Analysis of central mechanisms involved in gastric mucosal integrity]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:3 Topics: Animals; Arachidonic Acids; beta-Endorphin; Clonidine; Endocannabinoids; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Excitatory Amino Acids; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nociceptin; Oligopeptides; Opioid Peptides; Oxazoles; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Opioid; Rilmenidine; Stomach Ulcer	2008
The antinociceptive properties of reboxetine in acute pain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:10 Topics: Adrenergic Antagonists; Analgesics; Animals; Antidepressive Agents; Clonidine; Disease Models, Animal; Drug Interactions; Male; Mice; Mice, Inbred ICR; Morphine; Morpholines; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Reboxetine; Receptors, Opioid, mu	2009
The role of opioid system and its interaction with sympathetic nervous system in the processing of polycystic ovary syndrome modeling in rat. Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Disease Models, Animal; Estradiol; Female; Gonadal Steroid Hormones; Naltrexone; Narcotic Antagonists; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Opioid; Sympathetic Nervous System; Yohimbine	2011
Opioid dependence. American family physician, 2012, Sep-15, Volume: 86, Issue:6 Topics: Buprenorphine; Clonidine; Evidence-Based Medicine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Prognosis; Risk Factors; Substance Withdrawal Syndrome; Time Factors	2012
Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:12 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Clonidine; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Naltrexone; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid, kappa	2013
A novel non-opioid protocol for medically supervised opioid withdrawal and transition to antagonist treatment. The American journal of drug and alcohol abuse, 2018, Volume: 44, Issue:3 Topics: Adult; Amines; Analgesics, Opioid; Buprenorphine; Clonidine; Counseling; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2018
Therapeutic challenges in comorbid obsessive compulsive disorder with substance use. Asian journal of psychiatry, 2018, Volume: 31 Topics: Adrenergic alpha-2 Receptor Agonists; Clonazepam; Clonidine; Combined Modality Therapy; Fluoxetine; GABA Modulators; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Relaxation Therapy; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders	2018
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report. Substance abuse, 2019, Volume: 40, Issue:2 Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics	2019
Conjugate vaccine produces long-lasting attenuation of fentanyl vs. food choice and blocks expression of opioid withdrawal-induced increases in fentanyl choice in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:10 Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Behavior, Animal; Choice Behavior; Clonidine; Drug-Seeking Behavior; Feeding Behavior; Female; Fentanyl; Food; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Tetanus Toxoid; Vaccines, Conjugate	2019
Extinction and reinstatement of methamphetamine-induced conditioned place preference in zebrafish. Addiction biology, 2023, Volume: 28, Issue:12 Topics: Animals; Clonidine; Extinction, Psychological; Methamphetamine; Morphine; Naltrexone; Recurrence; Zebrafish	2023