clonidine has been researched along with midazolam in 121 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.83) | 18.7374 |
| 1990's | 27 (22.31) | 18.2507 |
| 2000's | 43 (35.54) | 29.6817 |
| 2010's | 39 (32.23) | 24.3611 |
| 2020's | 11 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Giacomini, KM; Schaner, ME; Zhang, L | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Holdcroft, A; Nicol, ME | 1 |
| Wakita, K | 1 |
| Cmielewski, PL; Cousins, MJ; Gourlay, GK; Owen, H; Plummer, JL | 1 |
| Hijzen, TH; Rijnders, HJ; Slangen, JL | 1 |
| Bartels, H; Huber, FT; Siewert, JR | 1 |
| Bach, A; Böhrer, H; Layer, M; Werning, P | 1 |
| Gaumann, DM; Tyce, GM; Yaksh, TL | 1 |
| Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Wüllner, U | 1 |
| Berge, KH; Strickland, RA | 1 |
| Fujimoto, JM; Rady, JJ | 1 |
| Cicala, R; Kent, M; Quíntin, L; Thomsen, B | 1 |
| Peduto, VA; Piga, M; Pisanu, GM | 1 |
| Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H | 1 |
| Borg, PA; Krijnen, HJ | 1 |
| Dohi, S; Iida, H; Kasamatsu, M; Katoh, H; Takenaka, M; Tashiro, T | 1 |
| Bayon, MC; Boucaud, C; Bouilloc, X; Brudon, JR; Butin, E; Danays, T; Frehring, B; Ghignone, M; Levron, JC; Petit, P; Quintin, L; Tassan, H; Tissot, S; Viale, JP | 1 |
| Tryba, M | 1 |
| Kyoda, N; Machida, T; Misaki, T; Murai, T; Sawada, S; Takada, K | 1 |
| Malinovsky, JM; Pinaud, M | 1 |
| Aantaa, R; Kanto, J; Kirvelä, O; Taittonen, M | 1 |
| Ishizuka, I; Kakoi, H; Kawasaki, J; Kawazoe, T; Kodaka, M; Miyao, H; Okamoto, Y | 1 |
| Bause, H; Möllenberg, O; Prause, A; Scholz, J; Schulte am Esch, J; Wappler, F | 1 |
| Chlouverakis, G; Fraidakis, O; Georgopoulou, G; Kochiadakis, G; Michaloudis, D; Petrou, A; Pollard, BJ | 1 |
| Aantaa, R; Kanto, JH; Kirvelä, OA; Taittonen, MT | 1 |
| Bertschy, G; Cucchia, AT; Ferrero, F; Monnat, M; Spagnoli, J | 1 |
| Benhamou, D; Mercier, FJ | 1 |
| Bergendahl, HT; Eksborg, S; Kogner, P; Lönnqvist, PA | 1 |
| Baur, CP; Eberhart, LH; Georgieff, M; Novatchkov, N; Schricker, T | 1 |
| Frank, T; Radow, L; Thieme, V | 1 |
| Bause, H; Prause, A; Scholz, J; Schulte am Esch, J; Wappler, F | 1 |
| Fazi, L; Jantzen, EC; Kurth, CD; Rose, JB; Watcha, MF | 1 |
| Bressem, M; Kulka, PJ; Tryba, M | 1 |
| Hanaoka, K; Nishiyama, T | 1 |
| Correia, ML; de Lemos Neto, M; de Oliveira, LF; Resende, AC; Rios, AA; Santos, EJ; Soares de Moura, R; Tano, T | 1 |
| Beer, GM; Emanuel, B; Kompatscher, P; Meyer, VE; Seifert, B; Spicher, I | 1 |
| Frank, T; Heinke, W; Schmädicke, I; Wehner, M | 1 |
| Carr, DB; Cousins, MJ; Goudas, LC; Walker, SM | 1 |
| Ishiyama, T; Kashimoto, S; Kumazawa, T; Matsukawa, T; Oguchi, T | 1 |
| Dietrich, PJ; Grottke, O; Krause, TH; Müller, J; Wappler, F | 1 |
| Constant, I; Leport, Y; Moutard, ML; Murat, I; Richard, P | 1 |
| Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Nordenberg, L; Oddby, E; Ruthström, E; Zetterqvist, H | 1 |
| Cameron, DJ; Palmer, GM | 1 |
| Fischer, M; Franck, M; Martin, J; Parsch, A; Spies, C; Wernecke, KD | 1 |
| Honda, K; Inomata, S; Misawa, S; Nagashima, A; Tanaka, E | 1 |
| Dalsasso, M; Innocente, F; Ori, C; Tresin, P; Veronese, S | 1 |
| Tobias, JD | 1 |
| Ishiyama, T; Kumazawa, T; Oguchi, T; Zhao, H | 1 |
| Bergendahl, H; Eksborg, S; Lönnqvist, PA | 1 |
| Honda, K; Inomata, S; Nakamura, T; Tanaka, E | 1 |
| Backman, JT; Lilja, JJ; Neuvonen, PJ | 1 |
| De Groote, F; De Hert, S; De Villé, A; Dierick, A; Tazeroualti, N; Van der Linden, P | 1 |
| Auler, JO; Bandeira, D; Bertacchi, MF; Schmidt, AP; Simões, CM; Valinetti, EA | 1 |
| Arici, G; Erman, M; Ertugrul, F; Karsli, B; Kayacan, N; Nacitarhan, C; Sadan, G | 1 |
| Almenrader, N; Coccetti, B; Haiberger, R; Passariello, M; Pietropaoli, P | 1 |
| Alexi-Meskishvili, V; Berger, F; Hübler, M; Lemmer, J; Pohl-Schickinger, A; Redlin, M; Stiller, B | 1 |
| Carvalho, HG; Modolo, NS; Nascimento, Jdos S; Santos, KP; Silva, RC | 1 |
| Bozdogan, N; Yildirim, SV | 1 |
| Bein, B; Kaufmann, M; Ledowski, T; Lemke, T; Paris, A; Renz, P; Scholz, J; Tonner, PH | 1 |
| Busch, HJ; Schwab, T; Supady, A | 1 |
| Inagaki, H; Kiyokawa, Y; Mori, Y; Takeuchi, Y | 1 |
| Brasher, C; Bruneau, B; Constant, I; Dahmani, S; Golmard, J; Murat, I; Nivoche, Y; Skhiri, A; Stany, I | 1 |
| Cao, J; Miao, X; Shi, X; Xu, J | 1 |
| Ivleva-Sauerborn, A; Seifert, B; Spahn, DR; Zalunardo, MP | 1 |
| Chauhan, S; Ghai, B; Ram, J; Wig, J | 1 |
| Patel, N; Trivedi, V | 1 |
| Kasaba, T | 1 |
| Kantharaja, HE; Shaikh, SI | 1 |
| Brummett, CM; Williams, BA | 1 |
| da Silva, PS; Passos, RM; Waisberg, DR | 1 |
| Grätz, KW; Mutzbauer, TS; Studer, FR | 1 |
| Hess, L; Horacek, J; Kurzova, A; Malek, J; Palenicek, T; Scigel, V | 1 |
| Bruder, M; Byhahn, C; Eibach, S; Marquardt, G; Seifert, V; Setzer, M; Weise, LM | 1 |
| Gamble, C; Sinha, I; Spowart, C; Williamson, P; Wolf, A | 1 |
| Arnup, SJ; Clifford, M; Evans, J; Larson, GE | 1 |
| Burduk, PK; Cywinski, JB; Kazmierczak, W; Kusza, K; Wawrzyniak, K | 1 |
| Colby, CE; Nemergut, ME; Yaster, M | 1 |
| Li, J; Wang, Y; Zhang, C; Zhao, D | 1 |
| Anand, LK; Kazal, S; Mitra, S | 1 |
| Cyna, AM; Knight, N; Lambert, P; Middleton, P | 1 |
| Bailard, NS; Flores, RA; Ortiz, J | 1 |
| Balling, G; Behr, J; Blickheuser, R; Dohna-Schwake, C; Gebauer, C; Hahn, M; Harnischmacher, U; Hentschel, R; Hering, F; Hoehn, T; Hünseler, C; Huth, RG; Lieser, U; Möller, O; Müller, A; Müller, C; Röhlig, C; Roth, B; Schubert, S; Trieschmann, U; Wassmer, G | 1 |
| Pretto, G; Silva, E; Westphal, GA | 1 |
| Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P | 1 |
| Cohen, PZ; Ibinson, JW; Mangione, MP; Scanlan, RL; Williams, BA | 1 |
| Cohen, PZ; Ibinson, JW; Kmatz, AM; Mangione, MP; Modrak, RT; Rakesh, H; Tonarelli, EJ; Williams, BA | 1 |
| Gögenur, I; Halladin, NL; Hansen, MV; Møller, AM; Rosenberg, J | 1 |
| Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC | 1 |
| Boland, A; Gamble, C; Granville, H; McKay, A; Petrou, S; Spowart, C; Sutherland, A; Wolf, A | 1 |
| Breatnach, C; Cousins, G; Doherty, DR; Gallagher, PJ; Hayden, JC; Healy, M; Howlett, MM | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
| Aro, R; Herodes, K; Kipper, K; Lutsar, I; Metsvaht, T; Standing, JF; Veigure, R | 1 |
| Baarslag, MA; Dijk, MV; Giannuzzi, V; Hanning, SM; Larsson, P; Metsvaht, T; Neubert, A; Pokorná, P; Rascher, W; Rawcliffe, L; Roberts, D; Rosmalen, JV; Sheng, Y; Simonetti, A; Standing, JF; Tibboel, D; Winslade, J | 1 |
| Bint, L; Czarniak, P; Landwehr, C; Parsons, R; Richardson, J; Sunderland, B | 1 |
| Breatnach, CV; Cousins, G; Dawkins, I; Doherty, DR; Gallagher, PJ; Hayden, JC; Healy, M; Leacy, FP | 1 |
| Sun, S; Tan, D; Wang, F; Xia, H | 1 |
| Donato, J; Lewis, T; Rao, K | 1 |
| Barbosa, TP; Bastos, AS; Beccaria, LM; Silva, DCD | 1 |
| Madsen, BK; Møller, AM; Rosenberg, J; Zetner, D | 1 |
| Ahne, G; Eberl, S; Neubert, A; Standing, J; Toni, I | 1 |
| Bromfalk, Å; Engström, Å; Hultin, M; Myrberg, T; Walldén, J | 2 |
| Bourdon, O; Dauger, S; Deho, A; Prot-Labarthe, S; Sadozai, L | 1 |
| Haney, M; Hedlund, L; Hult, AC; Johansson, G; Winsö, O; Zickerman, C | 1 |
| Huang, RR; Li, YL; Qu, SS; Yang, CQ; Yu, KH; Zhang, JM | 1 |
| Fu, Y; Jiang, Y; Lang, B; Zhang, Q | 1 |
| Brorsson, C; Haney, M; Hultin, M; Johansson, G; Winsö, O; Zickerman, C | 1 |
| Shang, L; Zhao, Y | 1 |
23 review(s) available for clonidine and midazolam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Neurotoxicity of intrathecally administrated agents].
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Baclofen; Calcitonin; Clonidine; Humans; Meninges; Midazolam; Nerve Fibers; Somatostatin; Spinal Cord | 1996 |
Promising non-narcotic analgesic techniques for labour.
Topics: Analgesia, Obstetrical; Analgesics, Non-Narcotic; Clonidine; Epinephrine; Female; Humans; Midazolam; Neostigmine; Obstetric Labor Complications; Pain; Piperidines; Pregnancy; Receptors, N-Methyl-D-Aspartate; Remifentanil | 1998 |
Combination spinal analgesic chemotherapy: a systematic review.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Antineoplastic Agents; Cholinesterase Inhibitors; Clonidine; GABA Modulators; Humans; Injections, Spinal; Midazolam; Neoplasms; Neostigmine; Pain; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate | 2002 |
Clonidine in paediatric anaesthesia: review of the literature and comparison with benzodiazepines for premedication.
Topics: Analgesics; Anesthesia; Anti-Anxiety Agents; Benzodiazepines; Child; Child, Preschool; Clonidine; Humans; Infant; Midazolam; Preanesthetic Medication | 2006 |
Premedication with clonidine is superior to benzodiazepines. A meta analysis of published studies.
Topics: Adrenergic alpha-Agonists; Anesthesia Recovery Period; Benzodiazepines; Child; Child, Preschool; Clonidine; Critical Care; Data Interpretation, Statistical; Female; Humans; Infant; Length of Stay; Male; Midazolam; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting; Premedication; Psychomotor Agitation; Publication Bias; Randomized Controlled Trials as Topic | 2010 |
[Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia].
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Dexmedetomidine; Droperidol; Drug Compounding; Epinephrine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium Sulfate; Midazolam; Morphine; Neostigmine | 2010 |
Additives to local anesthetics for peripheral nerve blockade.
Topics: Anesthetics, Local; Buprenorphine; Clonidine; Dexmedetomidine; Epinephrine; Humans; Midazolam; Nerve Block; Sodium Bicarbonate; Tramadol | 2011 |
The role of systematic reviews in pharmacovigilance planning and Clinical Trials Authorisation application: example from the SLEEPS trial.
Topics: Adolescent; Child; Child, Preschool; Clonidine; Female; Humans; Hypnotics and Sedatives; Infant; Male; Midazolam; Pharmacovigilance; Randomized Controlled Trials as Topic; Sympatholytics | 2013 |
Sedation and analgesia to facilitate mechanical ventilation.
Topics: Analgesics; Analgesics, Opioid; Benzodiazepines; Clonidine; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Intensive Care, Neonatal; Intubation, Intratracheal; Ketamine; Midazolam; Neuromuscular Blockade; Pain; Pain Management; Pain Measurement; Respiration, Artificial | 2013 |
Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Clonidine; Delirium; Double-Blind Method; Humans; Methyl Ethers; Midazolam; Preanesthetic Medication; Randomized Controlled Trials as Topic; Sevoflurane | 2013 |
Clonidine premedication for postoperative analgesia in children.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Child; Clonidine; Fentanyl; Humans; Midazolam; Pain, Postoperative; Preanesthetic Medication; Randomized Controlled Trials as Topic | 2014 |
Additives to local anesthetics for peripheral nerve blocks: Evidence, limitations, and recommendations.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Buprenorphine; Clonidine; Dexamethasone; Dexmedetomidine; Drug Combinations; Epinephrine; Evidence-Based Medicine; Humans; Ketamine; Magnesium Compounds; Midazolam; Nerve Block; Peripheral Nerves; Sodium Bicarbonate; Tramadol; Vasoconstrictor Agents | 2014 |
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Clonidine; Desflurane; Dexmedetomidine; Halothane; Humans; Isoflurane; Methyl Ethers; Midazolam; Propofol; Sevoflurane | 2014 |
Melatonin for pre- and postoperative anxiety in adults.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clonidine; Drug Administration Schedule; Humans; Melatonin; Midazolam; Postoperative Care; Preoperative Care; Publication Bias; Randomized Controlled Trials as Topic; Surgical Procedures, Operative | 2015 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors | 2015 |
Efficacy of α2-Agonists for Sedation in Pediatric Critical Care: A Systematic Review.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Child; Child, Preschool; Clonidine; Conscious Sedation; Critical Care; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Pediatric; Male; Midazolam; Treatment Outcome | 2016 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theorem; Child; Clonidine; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Humans; Ketamine; Midazolam; Network Meta-Analysis; Ophthalmologic Surgical Procedures; Propofol; Psychomotor Agitation; Remifentanil; Sevoflurane; Sufentanil | 2019 |
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modality Therapy; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Pain; Pain Management; Pharmacogenomic Variants; Precision Medicine; Remifentanil | 2019 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Administration Schedule; Humans; Melatonin; Midazolam; Middle Aged; Oxazepam; Postoperative Care; Postoperative Complications; Preoperative Care; Publication Bias; Randomized Controlled Trials as Topic; Surgical Procedures, Operative | 2020 |
Safety of clonidine used for long-term sedation in paediatric intensive care: A systematic review.
Topics: Child; Clonidine; Critical Care; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Observational Studies as Topic | 2021 |
Comparison of different sedatives in children before general anaesthesia for selective surgery: A network meta-analysis.
Topics: Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Ketamine; Melatonin; Midazolam; Network Meta-Analysis | 2022 |
A comparative evaluation of intranasal α2-adrenoceptor agonists and intranasal midazolam as premedication in pediatric sedation: A meta-analysis of randomized controlled trials.
Topics: Administration, Intranasal; Anesthesia, General; Child; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Premedication; Randomized Controlled Trials as Topic; Receptors, Adrenergic | 2023 |
45 trial(s) available for clonidine and midazolam
| Article | Year |
|---|---|
[Treatment of postoperative alcohol withdrawal syndrome after esophageal resection].
Topics: Alcohol Withdrawal Delirium; Clonidine; Esophageal Neoplasms; Esophagectomy; Ethanol; Humans; Midazolam; Neurologic Examination; Postoperative Complications; Respiration, Artificial | 1990 |
Effect of clonidine on myocardial ischaemia: a double-blind pilot trial.
Topics: Anesthesia, Intravenous; Cardiopulmonary Bypass; Clonidine; Double-Blind Method; Electrocardiography; Humans; Incidence; Midazolam; Myocardial Ischemia; Pancuronium; Pilot Projects; Placebos; Sufentanil | 1993 |
Oral clonidine premedication reduces vomiting in children after strabismus surgery.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Child, Preschool; Clonidine; Diazepam; Diclofenac; Double-Blind Method; Female; Humans; Incidence; Length of Stay; Male; Midazolam; Neuromuscular Nondepolarizing Agents; Pain, Postoperative; Placebos; Postoperative Complications; Preanesthetic Medication; Premedication; Prospective Studies; Strabismus; Vecuronium Bromide; Vomiting | 1995 |
[Tizanidine for preanesthetic medication].
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia, General; Clonidine; Elective Surgical Procedures; Female; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication | 1996 |
Clonidine for major vascular surgery in hypertensive patients: a double-blind, controlled, randomized study.
Topics: Administration, Oral; Adult; Alfentanil; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; Aortic Diseases; Blood Circulation; Cardiotonic Agents; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Intraoperative Care; Isoflurane; Isoproterenol; Male; Midazolam; Middle Aged; Placebos; Premedication; Vasoconstrictor Agents | 1996 |
Effects of clonidine on intravenous sedation with midazolam.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Intravenous; Clonidine; Conscious Sedation; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Preanesthetic Medication; Single-Blind Method | 1995 |
Cardiovascular and metabolic responses to clonidine and midazolam premedication.
Topics: Adrenergic alpha-Agonists; Adult; Anti-Anxiety Agents; Clonidine; Double-Blind Method; Electrocardiography; Energy Metabolism; Female; Hemodynamics; Hemoglobins; Humans; Injections, Intramuscular; Male; Midazolam; Middle Aged; Oxygen Consumption; Preanesthetic Medication | 1997 |
[The effects of premedication on induction doses of propofol and hemodynamic responses during induction].
Topics: Adult; Atropine; Clonidine; Diazepam; Drug Interactions; Female; Hemodynamics; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Preanesthetic Medication; Propofol | 1997 |
The influence of premedication on heart rate variability.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antihypertensive Agents; Blood Pressure; Clonidine; Electrocardiography; Heart Rate; Humans; Midazolam; Morphine; Premedication; Signal Processing, Computer-Assisted; Sympatholytics | 1998 |
The effect of clonidine or midazolam premedication on perioperative responses during ketamine anesthesia.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Blood Pressure; Carbon Dioxide; Clonidine; Double-Blind Method; Drug Interactions; Epinephrine; Female; Heart Rate; Humans; Ketamine; Male; Midazolam; Middle Aged; Norepinephrine; Oxygen; Oxygen Consumption; Placebos; Premedication | 1998 |
Neuropeptide Y response to tracheal intubation in anaesthetized children: effects of clonidine vs midazolam as premedication.
Topics: Adrenergic alpha-Agonists; Anti-Anxiety Agents; Biomarkers; Child; Child, Preschool; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Infant; Intubation, Intratracheal; Male; Midazolam; Neuropeptide Y; Premedication; Prospective Studies; Stress, Physiological | 1999 |
[Clonidine compared to midazolam for intravenous premedication for ambulatory procedures. A controlled double blind study in ASA 1 patients].
Topics: Adjuvants, Anesthesia; Adolescent; Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Anesthesia, General; Clonidine; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Midazolam; Molar, Third; Preanesthetic Medication; Tooth Extraction | 2000 |
[Premedication in maxillofacial surgery under total intravenous anesthesia . Effects of clonidine compared to midazolam on the perioperative course].
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia, Intravenous; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Midazolam; Oral Surgical Procedures; Pain, Postoperative; Postoperative Nausea and Vomiting; Preanesthetic Medication; Prospective Studies | 2000 |
A comparison of oral clonidine and oral midazolam as preanesthetic medications in the pediatric tonsillectomy patient.
Topics: Adenoidectomy; Administration, Oral; Adrenergic alpha-Agonists; Anti-Anxiety Agents; Blood Pressure; Child; Child, Preschool; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Pain, Postoperative; Placebos; Preanesthetic Medication; Tonsillectomy | 2001 |
Clonidine prevents sevoflurane-induced agitation in children.
Topics: Anesthetics, Inhalation; Blood Pressure; Child; Child, Preschool; Clonidine; Double-Blind Method; Heart Rate; Humans; Male; Methyl Ethers; Midazolam; Psychomotor Agitation; Sevoflurane | 2001 |
Oral premedication for operations on the face under local anesthesia: a placebo-controlled double-blind trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anti-Anxiety Agents; Clonidine; Double-Blind Method; Face; Female; Humans; Male; Midazolam; Middle Aged; Morphine; Patient Acceptance of Health Care; Premedication; Prospective Studies | 2001 |
[Clonidine vs. Midazolam for premedication - comparison of the anxiolytic effect by using the STAI-test].
Topics: Adrenergic alpha-Agonists; Adult; Anti-Anxiety Agents; Anxiety; Clonidine; Female; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Psychological Tests | 2002 |
The effects of clonidine premedication on the blood pressure and tachycardiac responses to ephedrine in elderly and young patients during propofol anesthesia.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Aged; Aging; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Clonidine; Double-Blind Method; Ephedrine; Female; Heart Rate; Humans; Male; Midazolam; Middle Aged; Oxygen; Preanesthetic Medication; Propofol; Tachycardia | 2003 |
[Comparison of premedication with clonidine and midazolam combined with TCI for orthopaedic shoulder surgery].
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Patient-Controlled; Anesthesia, Conduction; Anesthetics, Intravenous; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Narcotics; Orthopedic Procedures; Pain, Postoperative; Piperidines; Pirinitramide; Postoperative Nausea and Vomiting; Premedication; Propofol; Prospective Studies; Remifentanil; Shoulder | 2003 |
Agitation and changes of Bispectral Index and electroencephalographic-derived variables during sevoflurane induction in children: clonidine premedication reduces agitation compared with midazolam.
Topics: Adjuvants, Anesthesia; Analgesics; Anesthetics, Inhalation; Central Nervous System; Child; Child, Preschool; Clonidine; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Sedatives; Methyl Ethers; Midazolam; Preanesthetic Medication; Prospective Studies; Psychomotor Agitation; Sevoflurane; Time Factors; Tonsillectomy | 2004 |
Clonidine vs. midazolam as premedication in children undergoing adeno-tonsillectomy: a prospective, randomized, controlled clinical trial.
Topics: Adenoidectomy; Adrenergic alpha-Agonists; Anesthesia; Behavior; Child; Child, Preschool; Clonidine; Confusion; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infant; Male; Midazolam; Pain, Postoperative; Parents; Postoperative Complications; Postoperative Nausea and Vomiting; Preanesthetic Medication; Prospective Studies; Shivering; Tonsillectomy; Treatment Outcome | 2004 |
Low-dose ketamine with clonidine and midazolam for adult day care surgery.
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clonidine; Female; Hemodynamics; Humans; Ketamine; Male; Midazolam; Middle Aged; Postoperative Nausea and Vomiting; Respiratory Function Tests | 2005 |
[Effects of clonidine and midazolam on postoperative shivering, nausea, and vomiting].
Topics: Administration, Oral; Aged; Anesthesia, Epidural; Anesthesia, General; Clonidine; Female; Humans; Male; Midazolam; Middle Aged; Postoperative Nausea and Vomiting; Shivering; Sympatholytics | 2005 |
Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam--probes of CYP2C9, CYP1A2, and CYP3A4.
Topics: Adult; Anticoagulants; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Clonidine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Food-Drug Interactions; Half-Life; Humans; Male; Midazolam; Stereoisomerism; Vaccinium macrocarpon; Warfarin | 2007 |
Oral clonidine vs midazolam in the prevention of sevoflurane-induced agitation in children. a prospective, randomized, controlled trial.
Topics: Administration, Oral; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Infant; Male; Methyl Ethers; Midazolam; Postoperative Complications; Premedication; Prospective Studies; Psychomotor Agitation; Sevoflurane | 2007 |
Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children.
Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Anxiety; Blood Pressure; Carbon Dioxide; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Oxygen; Pain Measurement; Pain, Postoperative; Postoperative Complications; Preanesthetic Medication; Prospective Studies; Psychiatric Status Rating Scales | 2007 |
Premedication in children: a comparison of oral midazolam and oral clonidine.
Topics: Administration, Oral; Analgesics; Anxiety; Child; Child, Preschool; Clonidine; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Infant; Male; Midazolam; Patient Satisfaction; Pediatrics; Preanesthetic Medication | 2007 |
Sedative and cardiovascular effects of midazolam and diazepam alone or combined with clonidine in patients undergoing hemodynamic studies for suspected coronary artery disease.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure; Cineangiography; Clonidine; Conscious Sedation; Coronary Disease; Diazepam; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Monitoring, Physiologic; Prospective Studies | 2007 |
Effects of clonidine and midazolam premedication on bispectral index and recovery after elective surgery.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Adult; Anesthesia; Anesthetics, Intravenous; Clonidine; Double-Blind Method; Elective Surgical Procedures; Heart Rate; Humans; Male; Midazolam; Middle Aged; Pain Measurement; Postoperative Period; Premedication; Prospective Studies | 2009 |
Effects of premedication of midazolam or clonidine on perioperative anxiety and pain in children.
Topics: Administration, Oral; Analgesics; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Clonidine; Double-Blind Method; Humans; Midazolam; Pain; Perioperative Care; Prospective Studies; Treatment Outcome | 2009 |
[Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage].
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aging; Anesthesia; Anxiety; Blood Gas Analysis; Blood Pressure; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Patient Satisfaction; Postoperative Nausea and Vomiting; Premedication; Young Adult | 2010 |
Effects of clonidine on recovery after sevoflurane anaesthesia in children undergoing cataract surgery.
Topics: Anesthesia, Inhalation; Blood Pressure; Cataract Extraction; Child; Child, Preschool; Clonidine; Female; Heart Rate; Humans; Infant; Male; Methyl Ethers; Midazolam; Preanesthetic Medication; Psychomotor Agitation; Sevoflurane | 2010 |
A comparative clinical study of injection clonidine versus midazolam in supraclavicular brachial plexus block for sedation and postoperative analgesia: a study of 60 cases.
Topics: Adult; Analgesia; Analgesics; Brachial Plexus; Bupivacaine; Clonidine; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Postoperative Period; Time Factors; Young Adult | 2010 |
Comparison of clonidine and midazolam as anxiolytic premedication before wisdom tooth surgery: a randomized, double-blind, crossover pilot study.
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Blood Pressure; Clonidine; Cross-Over Studies; Dental Anxiety; Double-Blind Method; Female; Follow-Up Studies; Heart Rate; Humans; Male; Midazolam; Molar, Third; Patient Satisfaction; Pilot Projects; Premedication; Prospective Studies; Time Factors; Tooth Extraction; Treatment Outcome; Young Adult | 2012 |
The influence of clonidine on oral ketamine-midazolam premedication in intellectually disabled patients indicated for dental procedures: double-blind comparison of two sedation regimes.
Topics: Adult; Anesthesia, Dental; Clinical Protocols; Clonidine; Dental Care for Disabled; Disabled Persons; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Intellectual Disability; Ketamine; Male; Midazolam; Middle Aged; Preanesthetic Medication; Treatment Outcome | 2012 |
Efficacy and safety of local versus general anesthesia in stereotactic biopsies: a matched-pairs cohort study.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Algorithms; Anesthesia, General; Anesthesia, Local; Arterial Pressure; Biopsy; Blood Pressure; Brain Neoplasms; Clonidine; Cohort Studies; Data Interpretation, Statistical; Endpoint Determination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Prospective Studies; Registries; Stereotaxic Techniques; Young Adult | 2013 |
Premedication with clonidine before TIVA optimizes surgical field visualization and shortens duration of endoscopic sinus surgery - results of a clinical trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Blood Loss, Surgical; Chronic Disease; Clonidine; Endoscopy; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Nasal Polyps; Premedication; Prospective Studies; Sinusitis; Statistics, Nonparametric | 2013 |
Intranasal clonidine vs. midazolam as premedication in children: a randomized controlled trial.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Clonidine; Double-Blind Method; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Midazolam; Premedication | 2014 |
Continuous infusion of clonidine in ventilated newborns and infants: a randomized controlled trial.
Topics: Age Factors; Analgesics; Analgesics, Opioid; Clonidine; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Male; Midazolam; Prospective Studies; Respiration, Artificial; Substance Withdrawal Syndrome | 2014 |
Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Anti-Anxiety Agents; Bandages; Burns; Clonidine; Debridement; Dissociative Disorders; Double-Blind Method; Female; Humans; Ketamine; Male; Midazolam; Middle Aged; Severity of Illness Index; Young Adult | 2014 |
Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation) st
Topics: Adolescent; Child; Child, Preschool; Clonidine; Conscious Sedation; Cost-Benefit Analysis; Critical Illness; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Male; Midazolam; Therapeutic Equivalency; Treatment Outcome | 2014 |
The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial.
Topics: Adolescent; Analgesics, Opioid; Child; Child Development; Child, Preschool; Clonidine; Delirium; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Intensive Care Units; Midazolam; Research Design; Respiration, Artificial; Substance Withdrawal Syndrome; Treatment Failure | 2017 |
Preoperative anxiety in preschool children: A randomized clinical trial comparing midazolam, clonidine, and dexmedetomidine.
Topics: Anxiety; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Midazolam; Preanesthetic Medication | 2021 |
Clonidine Versus Midazolam Premedication and Postoperative Negative Behavioral Changes in Younger Children: A Randomized Controlled Trial.
Topics: Child; Clonidine; Double-Blind Method; Humans; Midazolam; Preanesthetic Medication; Premedication; Prospective Studies | 2022 |
Postoperative recovery in preschool-aged children: A secondary analysis of a randomized controlled trial comparing premedication with midazolam, clonidine, and dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives; Midazolam; Pain; Premedication | 2023 |
53 other study(ies) available for clonidine and midazolam
| Article | Year |
|---|---|
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Density of intrathecal agents.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Baclofen; Body Temperature; Cerebrospinal Fluid; Clonidine; Droperidol; Humans; Methadone; Midazolam; Naloxone; Specific Gravity; Temperature | 1992 |
[The antinociceptive effects of fentanyl, midazolam and clonidine and their interactions in the spinal dorsal horn].
Topics: Animals; Cats; Clonidine; Drug Combinations; Drug Synergism; Fentanyl; Injections, Spinal; Male; Midazolam; Pain; Spinal Cord | 1992 |
Antinociceptive and motor effects of intrathecal morphine combined with intrathecal clonidine, noradrenaline, carbachol or midazolam in rats.
Topics: Analgesics; Animals; Carbachol; Clonidine; Drug Synergism; Injections, Spinal; Male; Midazolam; Morphine; Motor Activity; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Effects of anxiety drugs on the modification of the acoustic startle reflex by noise gaps.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Anti-Anxiety Agents; Buspirone; Carbolines; Clonidine; Male; Midazolam; Rats; Reflex, Acoustic; Tetrahydronaphthalenes | 1991 |
Clonidine as a sedative adjunct in intensive care.
Topics: Clonidine; Critical Care; Drug Synergism; Drug Therapy, Combination; Fentanyl; Gastrectomy; Humans; Hypotension; Male; Midazolam; Middle Aged; Postoperative Care; Respiration, Artificial; Substance Withdrawal Syndrome | 1990 |
Effects of intrathecal morphine, clonidine, and midazolam on the somato-sympathoadrenal reflex response in halothane-anesthetized cats.
Topics: Adrenal Glands; Anesthesia, Inhalation; Animals; Catecholamines; Cats; Clonidine; Female; Halothane; Hemodynamics; Injections, Spinal; Male; Midazolam; Morphine; Pain; Reflex; Sympathetic Nervous System | 1990 |
Myorelaxant effect after intrathecal injection of antispastic drugs in rats.
Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Female; H-Reflex; Injections, Spinal; Male; Midazolam; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Rats; Rats, Mutant Strains; Reflex, Monosynaptic; Time Factors | 1989 |
Management of alcohol withdrawal.
Topics: Adrenergic alpha-Agonists; Alcoholism; Anti-Anxiety Agents; Clonidine; Diazepam; Humans; Midazolam; Substance Withdrawal Syndrome | 1995 |
Dynorphin A(1-17) mediates midazolam antagonism of morphine antinociception in mice.
Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Dynorphins; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Midazolam; Morphine; Naloxone; Naltrexone; Pain Measurement; Reaction Time; Spinal Cord | 1993 |
[Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus].
Topics: Aged; Autonomic Nervous System; Clonidine; Conscious Sedation; Female; Humans; Midazolam; Propofol; Severity of Illness Index; Tetanus | 1993 |
Long-term intrathecal administration of midazolam and clonidine.
Topics: Activities of Daily Living; Adolescent; Adult; Analgesics, Non-Narcotic; Clonidine; Female; Humans; Injections, Spinal; Low Back Pain; Male; Midazolam; Middle Aged; Musculoskeletal Diseases; Pain; Pain Measurement; Radiography; Shoulder Injuries | 1996 |
Choices in sedation: the balanced sedation technique.
Topics: Anesthesia, Conduction; Clonidine; Conscious Sedation; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Propofol | 1996 |
[Level concept of analgesic dosing in intensive care medicine with sufentanil].
Topics: Alfentanil; Analgesics, Opioid; Carbon Dioxide; Clonidine; Critical Care; Dose-Response Relationship, Drug; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intubation; Midazolam; Morphine; Respiration; Respiration, Artificial; Retrospective Studies; Sufentanil; Sympatholytics | 1998 |
Ultra-rapid opiate detoxification using deep sedation with oral midazolam: short and long-term results.
Topics: Administration, Oral; Adolescent; Adult; Anesthesia, General; Clonidine; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Heroin Dependence; Humans; Hypnotics and Sedatives; Length of Stay; Male; Methadone; Midazolam; Naltrexone; Narcotic Antagonists; Neurologic Examination; Ondansetron; Substance Withdrawal Syndrome; Treatment Outcome | 1998 |
Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Intravenous; Carbon Dioxide; Child; Child, Preschool; Clonidine; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Length of Stay; Long-Term Care; Male; Midazolam; Middle Aged; Respiration, Artificial; Respiratory Insufficiency; Retrospective Studies; Sufentanil; Survival Analysis | 2000 |
The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats.
Topics: Adrenergic alpha-Agonists; Analgesia; Anesthetics, Intravenous; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Hot Temperature; Inflammation; Male; Midazolam; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 2001 |
The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hypnotics and Sedatives; Indazoles; Male; Methyldopa; Midazolam; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Sleep; Thiopental | 2001 |
Use of intravenous midazolam and clonidine in cyclical vomiting syndrome: a case report.
Topics: Adrenergic alpha-Agonists; Child; Clonidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazolam; Postoperative Nausea and Vomiting; Recurrence | 2005 |
Practice of sedation and analgesia in German intensive care units: results of a national survey.
Topics: Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Clonidine; Critical Illness; Data Interpretation, Statistical; Drug Therapy, Combination; Fentanyl; Germany; Health Care Surveys; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Practice Guidelines as Topic; Propofol; Sufentanil; Surveys and Questionnaires | 2005 |
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
Topics: Animals; Cimetidine; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ketoconazole; Lidocaine; Microsomes, Liver; Midazolam; Neuromuscular Depolarizing Agents; Pentobarbital; Pharmacogenetics; Premedication; Rats; Theophylline; Thiamylal | 2005 |
Dexmedetomidine in the treatment of cyclic vomiting syndrome.
Topics: Adrenergic alpha-Agonists; Bradycardia; Child; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Midazolam; Periodicity; Respiration; Syndrome; Vomiting | 2005 |
Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.
Topics: Amides; Anesthetics, Local; Bupivacaine; Cells, Cultured; Cimetidine; Clonidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Lidocaine; Microsomes, Liver; Midazolam; Premedication; Ropivacaine; Thiamylal; Vecuronium Bromide | 2006 |
The effects of opioids, local anesthetics and adjuvants on isolated pregnant rat uterine muscles.
Topics: Alfentanil; Amides; Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Female; Isometric Contraction; Meperidine; Mepivacaine; Midazolam; Myometrium; Oxytocics; Oxytocin; Piperidines; Pregnancy; Rats; Rats, Wistar; Remifentanil; Ropivacaine; Uterine Contraction | 2007 |
Intravenous clonidine infusion in infants after cardiovascular surgery.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Blood Pressure; Body Temperature; Clonidine; Female; Fentanyl; Heart Defects, Congenital; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Male; Midazolam; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2008 |
Intranasal clonidine as a premedicant: three cases with unique indications.
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Anti-Anxiety Agents; Child; Clonidine; Humans; Midazolam; Premedication | 2008 |
["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure].
Topics: 4-Butyrolactone; Acute Kidney Injury; Adrenergic alpha-Agonists; Benzodiazepines; Clonidine; GABA Modulators; Humans; Intubation, Intratracheal; Male; Midazolam; Myoclonus; Renal Dialysis; Respiration, Artificial; Respiratory Insufficiency; Rhabdomyolysis; Solvents; Substance Withdrawal Syndrome; Young Adult | 2009 |
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Models, Animal; Male; Midazolam; Phenelzine; Pheromones; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Reflex, Startle | 2010 |
A comparative clinical study of injection clonidine versus midazolam in supraclavicular brachial plexus block for sedation and postoperative analgesia.
Topics: Analgesics; Brachial Plexus; Clonidine; Conscious Sedation; Humans; Hypnotics and Sedatives; Midazolam; Nerve Block; Pain, Postoperative | 2011 |
Withdrawal treatment with clonidine after prolonged use of chloral hydrate in a pediatric intensive care patient.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Chloral Hydrate; Clonidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Intensive Care, Neonatal; Lorazepam; Male; Methadone; Midazolam; Pneumonia; Respiratory Insufficiency; Substance Withdrawal Syndrome | 2011 |
How does the introduction of a pain and sedation management guideline in the paediatric intensive care impact on clinical practice? A comparison of audits pre and post guideline introduction.
Topics: Analgesics; Clonidine; Documentation; Guideline Adherence; Humans; Intensive Care Units, Pediatric; Medical Audit; Midazolam; Pain Management; Practice Guidelines as Topic; Substance Withdrawal Syndrome | 2013 |
Clinical benchmarks regarding multimodal peripheral nerve blocks for postoperative analgesia: observations regarding combined perineural midazolam-clonidine-buprenorphine-dexamethasone.
Topics: Analgesics; Benchmarking; Buprenorphine; Clonidine; Dexamethasone; Drug Therapy, Combination; Humans; Midazolam; Nerve Block; Pain, Postoperative | 2015 |
Research priorities regarding multimodal peripheral nerve blocks for postoperative analgesia and anesthesia based on hospital quality data extracted from over 1,300 cases (2011-2014).
Topics: Analgesics; Buprenorphine; Clonidine; Dexamethasone; Drug Therapy, Combination; Humans; Midazolam; Nerve Block; Pain, Postoperative | 2015 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |
A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive.
Topics: Analgesics; Chromatography, High Pressure Liquid; Clonidine; Humans; Limit of Detection; Midazolam; Morphine; Propanols; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Cross-sectional survey of off-label and unlicensed prescribing for inpatients at a paediatric teaching hospital in Western Australia.
Topics: Australia; Child; Child, Preschool; Clonidine; Drug Administration Routes; Drug Prescriptions; Female; Humans; Inpatients; Isoxazoles; Legislation, Drug; Male; Midazolam; Off-Label Use; Oxycodone; Pediatrics | 2019 |
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clinical Protocols; Clonidine; Dexmedetomidine; Equivalence Trials as Topic; Female; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Male; Midazolam; Morphine; Propensity Score; Respiration, Artificial; Retrospective Studies; Single-Blind Method; Time Factors | 2019 |
Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality.
Topics: Analgesics; Chi-Square Distribution; Clonidine; Critical Care; Cross-Sectional Studies; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Prevalence; Propofol | 2020 |
Use of continuous infusion of clonidine for sedation in critically ill infants and children.
Topics: Bradycardia; Child, Preschool; Clonidine; Critical Care; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Male; Midazolam; Morphine; Respiratory Insufficiency; Retrospective Studies | 2022 |
Preoperative anxiety level is not associated with postoperative negative behavioral changes in premedicated children.
Topics: Anesthesia; Anxiety; Child; Clonidine; Humans; Midazolam; Postoperative Period | 2023 |
Comment on "Continuous clonidine infusion: an alternative for children on mechanical ventilation".
Topics: Child; Clonidine; Humans; Hypnotics and Sedatives; Midazolam; Respiration, Artificial | 2023 |