clonidine and mianserin

clonidine has been researched along with mianserin in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199044 (64.71)18.7374
1990's9 (13.24)18.2507
2000's12 (17.65)29.6817
2010's3 (4.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Topliss, JG; Yoshida, F1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Antonaccio, MJ; Liebman, J; Robson, RD; Saelens, JK1
Doxey, JC; Everitt, J; Metcalf, G1
Fludder, JM; Leonard, BE2
Klimek, V; Maj, J; Mogilnicka, E1
Roba, J; van Dorsser, W1
Bonanno, G; Maura, G; Raiteri, M1
Barone, D; Spignoli, G1
Becker, CA; Commissaris, RL; Ellis, DM; Fontana, DJ; Hill, TJ; Schefke, DM1
Itoh, Y; Nishibori, M; Oishi, R; Saeki, K1
Maura, G; Pittaluga, A; Raiteri, M; Ulivi, M1
Cerrito, F; Preziosi, P1
Asakura, M; Tsukamoto, T1
Funato, H; Kanehiro, H; Kayamoto, M; Kojima, M; Mizota, M; Mizuguchi, K; Nakayama, K; Oikawa, Y; Sato, M; Takarada, T1
Pinder, RM1
Neal, BS; Sparber, SB1
Doğan, N; Ilhan, M; Kayaalp, SO; Tuncer, M1
Hashizume, H; Ito, C; Niho, T; Shibutani, Y; Yamaguchi, K1
Agnoli, A; Manna, V; Martucci, N; Porto, C1
Agnoli, A; Denaro, A; Manna, V; Martucci, N; Ruggieri, S1
Svensson, TH1
Sugrue, MF2
Atrens, DM; Hunt, GE; Johnson, GF1
Barbaz, B; Bernard, P; Braunwalder, A; Kim, HS; Liebman, JM; Lovell, RA; Robson, RD; Stone, G; Wasley, JW; Welch, J1
Cella, SG; Mantegazza, P; Morgese, M; Müller, EE; Picotti, GB1
de Vries, JB; Dijkstra, D; Hazelhoff, B; Horn, AS; Mulder, TB; Timmermans, P; Wynberg, H1
Curtis-Prior, PB; Tan, S1
Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG1
Engberg, G; Svensson, TH1
García-Sevilla, JA; Hollingsworth, PJ; Smnith, CB1
Appia, F; Chariot, J; Pascaud, X; Rozé, C; Vaille, C1
Andréjak, M; Dabiré, H; Lucet, B; Mouillé, P; Pommier, Y; Schmitt, H1
Scuvée-Moreau, JJ; Svensson, TH1
Nickolson, VJ; van Delft, AM; Wieringa, JH1
Elliott, HL; McLean, K; Reid, JL; Sumner, DJ2
Kalkman, HO; Timmermans, PB; van Gelderen, EM; van Zwieten, PA1
Davies, CL; Green, AR; Heal, DJ; Lister, S; Molyneux, SG; Smith, SL1
Carvajal García-Pando, A; González Martínez de Zárate, JL; Velasco Martín, A1
Charney, DS; Heninger, GR; Sternberg, DE1
Dyr, W; Kostowski, W; Zacharski, B1
Elliott, HL; Reid, JL; Whiting, B1
Dwoskin, LP; Sparber, SB1
Ashton, D; Leysen, JE; Wauquier, A1
Broekkamp, CL; Garrigou, D; LLoyd, KG1
Blier, P; de Montigny, C; Mongeau, R1
Bassareo, V; Di Chiara, G; Tanda, G1
Hayashi, T; Horiguchi, J; Koga, I; Nishikawa, T; Uchida, Y; Yamawaki, S1
Baettig, D; Baumann, P; Bertschy, G; Bondolfi, G; Bryois, C; Budry, P; Dascal, D; Martinet, C; Velardi, A1
Blier, P; de Montigny, C; Haddjeri, N1
Abo-Zena, RA; Bobek, MB; Dweik, RA1
Nath, C; Srivastava, SK1
Bengtsson, HJ; Hjorth, S; Johansson, J; Kele, J1
Cornil, C; Dumont, F; Fontaine, E; Machowski, R; Mendlewicz, J; Schittecatte, M; Wilmotte, J1
Bouvard, M; Rénéric, JP; Stinus, L1
Nash, JR; Nutt, DJ; Potokar, JP; Wilson, SJ1
Devoto, P; Flore, G; Gessa, GL; Longu, G; Pira, L1
Khazaal, Y; Kolly, S; Krenz, S; Miozzari, A; Rajeswaran, R; Zimmerman, G; Zullino, DF1
Ashkanian, M; Audrain, H; Bender, D; Hall, H; Hansen, SB; Jakobsen, S; Minuzzi, L; Rosenberg, R; Smith, DF; Stork, BS1
Arora, S; Vohora, D1

Reviews

3 review(s) available for clonidine and mianserin

ArticleYear
[Antidepressant drugs and central monoaminergic receptors].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1985, Volume: 5, Issue:4

    Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Blood Platelets; Brain; Brain Chemistry; Cats; Clonidine; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Mianserin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Yohimbine

1985
Adrenoreceptor interactions of the enantiomers and metabolites of mianserin: are they responsible for the antidepressant effect?
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Animals; Antidepressive Agents; Binding, Competitive; Biotransformation; Cerebral Cortex; Clonidine; Dibenzazepines; Isomerism; Mianserin; Norepinephrine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Serotonin Antagonists; Synaptic Transmission

1985
Central alpha-adrenoceptors and the mechanisms of action of antidepressant drugs.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain; Clonidine; Humans; Locus Coeruleus; Mianserin; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic, alpha; Thyroid Hormones

1984

Trials

8 trial(s) available for clonidine and mianserin

ArticleYear
Migraine and the noradrenergic control of vasomotricity: a study with alpha-2 stimulant and alpha-2 blocker drugs.
    Headache, 1985, Volume: 25, Issue:2

    Topics: Adult; Clinical Trials as Topic; Clonidine; Dibenzazepines; Double-Blind Method; Female; Headache; Humans; Male; Mianserin; Middle Aged; Migraine Disorders; Random Allocation; Stress, Psychological

1985
Headache and noradrenergic involvement: the effects of alpha 2-stimulants and alpha 2-antagonists.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Adult; Clinical Trials as Topic; Clonidine; Dibenzazepines; Double-Blind Method; Female; Headache; Humans; Male; Mianserin; Middle Aged; Migraine Disorders; Psychophysiologic Disorders; Stress, Psychological

1985
Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:1

    Topics: Aged; Blood Pressure; Clonidine; Dibenzazepines; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Mianserin; Middle Aged; Norepinephrine; Posture; Receptors, Adrenergic, alpha; Renin

1983
The effect of mianserin on alpha-2 adrenergic receptor function in depressed patients.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Depressive Disorder; Dibenzazepines; Double-Blind Method; Female; Growth Hormone; Humans; Male; Methoxyhydroxyphenylglycol; Mianserin; Middle Aged; Receptors, Adrenergic, alpha

1984
Pharmacodynamic studies on mianserin and its interaction with clonidine.
    European journal of clinical pharmacology, 1981, Volume: 21, Issue:2

    Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Dibenzazepines; Drug Interactions; Heart Rate; Humans; Male; Mianserin; Salivation

1981
Involvement of the alpha2-adrenergic system in polydipsia in schizophrenic patients: a pilot study.
    Psychopharmacology, 1997, Volume: 130, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Drinking Behavior; Female; Humans; Male; Mianserin; Middle Aged; Receptors, Adrenergic, alpha-2; Schizophrenia; Water Intoxication

1997
The association carbamazepine-mianserin in opiate withdrawal: a double blind pilot study versus clonidine.
    Pharmacological research, 1997, Volume: 35, Issue:5

    Topics: Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Carbamazepine; Clonidine; Double-Blind Method; Drug Combinations; Female; Hemodynamics; Heroin Dependence; Humans; Male; Mianserin; Pilot Projects; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome

1997
Neuroimaging of mirtazapine enantiomers in humans.
    Psychopharmacology, 2008, Volume: 200, Issue:2

    Topics: Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Autoradiography; Binding Sites; Binding, Competitive; Brain; Carbon Radioisotopes; Clonidine; Double-Blind Method; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Positron-Emission Tomography; Radioligand Assay; Radiopharmaceuticals; Stereoisomerism; Tissue Distribution; Young Adult

2008

Other Studies

57 other study(ies) available for clonidine and mianserin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Antagonism by mianserin and classical alpha-adrenoceptor blocking drugs of some cardiovascular and behavioral effects of clonidine.
    European journal of pharmacology, 1978, Feb-15, Volume: 47, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Behavior, Animal; Clonidine; Dibenzazepines; Electric Stimulation; Heart; Hemodynamics; Hypertension; Male; Mianserin; Rats; Time Factors

1978
Mianserin--an analysis of its peripheral autonomic actions.
    European journal of pharmacology, 1978, Sep-01, Volume: 51, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Electric Stimulation; Male; Mianserin; Norepinephrine; Phenoxybenzamine; Phentolamine; Rats; Tyramine; Yohimbine

1978
Chronic effects of mianserin on noradrenaline metabolism in the rat brain: evidence for a pre-synaptic alpha-adrenolytic action in vivo.
    Psychopharmacology, 1979, Volume: 64, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain Chemistry; Clonidine; Dibenzazepines; Drug Interactions; Male; Mianserin; Norepinephrine; Normetanephrine; Rats; Synapses; Yohimbine

1979
The effect of repeated administration of antidepressant drugs on the responsiveness of rats to catecholamine agonists.
    Journal of neural transmission, 1979, Volume: 44, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Dextroamphetamine; Imipramine; Male; Mianserin; Motor Activity; Rats

1979
Modification by antihypertensive drugs of amphetamine-induced stereotypy in rats.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Antihypertensive Agents; Behavior; Clonidine; Dextroamphetamine; Drug Interactions; Humans; Male; Mianserin; Prazosin; Rats; Stereotyped Behavior; Yohimbine

1979
Interaction between mianserin and clonidine in the rat brain in vivo.
    Communications in psychopharmacology, 1978, Volume: 2, Issue:6

    Topics: Amygdala; Animals; Brain Chemistry; Clonidine; Dibenzazepines; Drug Interactions; Male; Mianserin; Normetanephrine; Rats; Time Factors

1978
Presynaptic alpha 2-adrenoceptors mediating inhibition of noradrenaline and 5-hydroxytryptamine release in rat cerebral cortex: further characterization as different alpha 2-adrenoceptor subtypes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Dioxanes; Ethylmaleimide; GTP-Binding Proteins; Idazoxan; In Vitro Techniques; Male; Mianserin; Nerve Endings; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Signal Transduction; Synaptosomes; Thiazoles

1992
Investigations on the binding properties of the nootropic agent pyroglutamic acid.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:2

    Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; Chloride Channels; Clonidine; Diazepam; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Guinea Pigs; Male; Membrane Proteins; Mianserin; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Glutamate; Receptors, Glycine; Receptors, Histamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Purinergic; Receptors, Serotonin; Stereoisomerism

1990
Chronic antidepressant and clonidine treatment effects on conflict behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Clonidine; Conflict, Psychological; Desipramine; Female; Mianserin; Panic; Propiophenones; Rats; Rats, Inbred Strains; Time Factors; Trazodone

1990
In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Dialysis; Electrochemistry; Extracellular Space; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Mianserin; Microchemistry; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine

1990
Enhancement of endogenous GABA release from rat synaptosomal preparations is mediated by alpha 2-adrenoceptors pharmacologically different from alpha 2-autoreceptors.
    European journal of pharmacology, 1988, Nov-15, Volume: 157, Issue:1

    Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Male; Mianserin; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine

1988
Rat brain alpha 2-pre- and postsynaptic receptors are different or differently modulated?
    Journal of neuroscience research, 1985, Volume: 14, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Drug Administration Schedule; Male; Mianserin; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Synaptosomes; Yohimbine

1985
[Pharmacological studies of MO-8282, a new antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:6

    Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents; Biogenic Amines; Brain; Clonidine; Dopamine; Guinea Pigs; Male; Mianserin; Norepinephrine; Rats; Serotonin

1986
Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Animals; Body Temperature; Clonidine; Corticosterone; Dibenzazepines; Male; Mianserin; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Substance Withdrawal Syndrome

1986
Serotonin-induced contraction of canine saphenous vein: mediation by 5-HT1 receptors.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 274, Issue:2

    Topics: Animals; Clonidine; Dogs; Drug Interactions; Emetics; In Vitro Techniques; Ketanserin; Mianserin; Muscle Contraction; Naphthols; Piperidines; Receptors, Serotonin; Saphenous Vein; Serotonin; Yohimbine

1985
[Pharmacological properties of MO-8282, a novel antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:4

    Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Brain; Clonidine; Guinea Pigs; Imipramine; Male; Mianserin; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Reserpine; Tremorine

1986
The inability of chronic mianserin to block central alpha 2-adrenoceptors.
    European journal of pharmacology, 1980, Dec-05, Volume: 68, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Dibenzazepines; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats; Time Factors

1980
The tetracyclic antidepressant mianserin: evaluation of its blockade of presynaptic alpha-adrenoceptors in a self-stimulation model using clonidine.
    European journal of pharmacology, 1981, Mar-05, Volume: 70, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dibenzazepines; Drug Interactions; Electrodes, Implanted; Male; Mianserin; Rats; Self Stimulation

1981
CGS 7525A, a new, centrally active alpha 2 adrenoceptor antagonist.
    Life sciences, 1983, Jan-24, Volume: 32, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Clonidine; Male; Mesencephalon; Mianserin; Norepinephrine; Prazosin; Quinones; Rats; Rats, Inbred Strains; Spiperone; Yohimbine

1983
Presynaptic alpha 2 -adrenergic stimulation leads to growth hormone release in the dog.
    Life sciences, 1984, Jan-30, Volume: 34, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Clemastine; Clonidine; Dogs; Drug Interactions; Female; Growth Hormone; Male; Metergoline; Mianserin; Synapses; Triazoles; Yohimbine

1984
The hydroxy-hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: 4-Butyrolactone; Animals; Binding, Competitive; Brain Chemistry; Chemical Phenomena; Chemistry; Clonidine; Dopamine; Ergolines; Homovanillic Acid; Humans; In Vitro Techniques; Mianserin; Oxazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Serotonin; Stereotyped Behavior

1984
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
    Pharmacological research communications, 1984, Volume: 16, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine

1984
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats.
    British journal of pharmacology, 1980, Volume: 68, Issue:2

    Topics: Animals; Anthracenes; Blood Vessels; Cardiovascular System; Clonidine; Desipramine; Dibenzazepines; Drug Interactions; Heart; Male; Maprotiline; Mianserin; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord

1980
Mianserin: direct activation of brain norepinephrine neurons by blocking alpha 2-receptors.
    Communications in psychopharmacology, 1980, Volume: 4, Issue:3

    Topics: Action Potentials; Animals; Brain; Clonidine; Dibenzazepines; Locus Coeruleus; Male; Mianserin; Neurons; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1980
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
    European journal of pharmacology, 1981, Sep-24, Volume: 74, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine

1981
Clonidine inhibition of pancreatic secretion in rats: a possible central site of action.
    European journal of pharmacology, 1981, Dec-17, Volume: 76, Issue:4

    Topics: Animals; Clonidine; Deoxyglucose; Gastric Juice; Male; Mianserin; Pancreas; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1981
Interaction between mianserin and clonidine at alpha 2-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 318, Issue:4

    Topics: Animals; Blood Pressure; Chickens; Clonidine; Desipramine; Dibenzazepines; Dogs; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Heart Rate; Ileum; In Vitro Techniques; Male; Mianserin; Morphine; Muscle Contraction; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep

1982
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
    Journal of neural transmission, 1982, Volume: 54, Issue:1-2

    Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine

1982
Comparative pharmacology of mianserin, its main metabolites and 6-azamianserin.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:1

    Topics: Absorption; Aggression; Animals; Behavior, Animal; Brain; Cell Membrane; Clonidine; Dibenzazepines; Diuresis; Dopamine; Humans; In Vitro Techniques; Male; Mianserin; Mice; Mirtazapine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Serotonin

1982
Effects of (+)- and (-)-mianserin on alpha-adrenoceptors and tyramine-induced tachycardia in rats.
    European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3

    Topics: Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Heart Rate; Male; Methoxamine; Mianserin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stereoisomerism; Tyramine

1983
The effects of acute and repeated administration of various antidepressant drugs on clonidine-induced hypoactivity in mice and rats.
    Neuropharmacology, 1983, Volume: 22, Issue:8

    Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Male; Mianserin; Mice; Mice, Inbred C57BL; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1983
[Comparison of mianserin and yohimbine on presynaptic alpha 2-receptors].
    Archivos de farmacologia y toxicologia, 1983, Volume: 9, Issue:1

    Topics: Animals; Binding, Competitive; Clonidine; Dibenzazepines; Epinephrine; Female; Guinea Pigs; Male; Mianserin; Myenteric Plexus; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine

1983
A study of the effects of clonidine on the EEG in rats treated with single and multiple doses of antidepressants.
    Psychopharmacology, 1984, Volume: 84, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Electroencephalography; Male; Mianserin; Rats; Rats, Inbred Strains

1984
Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dibenzazepines; Double-Blind Method; Drug Interactions; Humans; Hypertension; Hypnotics and Sedatives; Male; Methyldopa; Mianserin; Middle Aged; Salivation

1983
Comparison of yohimbine, mianserin, chlorpromazine and prazosin as antagonists of the suppressant effect of clonidine on operant behavior.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpromazine; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Mianserin; Prazosin; Rats; Rats, Inbred Strains; Yohimbine

1983
Neurotransmitters and receptor binding in amygdaloid kindled rats: serotonergic and noradrenergic modulatory effects.
    Life sciences, 1980, Oct-27, Volume: 27, Issue:17

    Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain; Clonidine; Dexetimide; Electric Stimulation; Male; Mianserin; Muscimol; Propranolol; Rats; Seizures; Serotonin Antagonists

1980
Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomised rats.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:5

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Clonidine; Ergolines; Fenfluramine; Fluoxetine; Imipramine; Male; Metergoline; Mianserin; Olfactory Bulb; Quipazine; Rats; Serotonin; Serotonin Antagonists

1980
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
    Life sciences, 1981, Jan-26, Volume: 28, Issue:4

    Topics: Animals; Antidepressive Agents; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Desipramine; Fluoxetine; Glycols; Iprindole; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats

1981
Effects of long-term alpha-2 adrenergic antagonists and electroconvulsive treatments on the alpha-2 adrenoceptors modulating serotonin neurotransmission.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Clonidine; Dioxanes; Electroconvulsive Therapy; Idazoxan; Male; Mianserin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Synaptic Transmission

1994
Mianserin markedly and selectively increases extracellular dopamine in the prefrontal cortex as compared to the nucleus accumbens of the rat.
    Psychopharmacology, 1996, Volume: 123, Issue:2

    Topics: Animals; Clonidine; Dopamine; Dose-Response Relationship, Drug; Male; Mianserin; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine

1996
Acute and long-term actions of the antidepressant drug mirtazapine on central 5-HT neurotransmission.
    Journal of affective disorders, 1998, Volume: 51, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Locus Coeruleus; Mianserin; Mirtazapine; Neural Pathways; Neurons; Norepinephrine; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin; Synaptic Transmission

1998
Hypertensive urgency induced by an interaction of mirtazapine and clonidine.
    Pharmacotherapy, 2000, Volume: 20, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Antihypertensive Agents; Clonidine; Depression; Drug Interactions; Humans; Hypertension; Male; Mianserin; Mirtazapine

2000
The differential effects of calcium channel blockers in the behavioural despair test in mice.
    Pharmacological research, 2000, Volume: 42, Issue:4

    Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil

2000
Interaction of the antidepressant mirtazapine with alpha2-adrenoceptors modulating the release of 5-HT in different rat brain regions in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:4-5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Brain; Clonidine; Male; Mianserin; Microdialysis; Mirtazapine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin

2000
Mirtazapine, but not fluvoxamine, normalizes the blunted REM sleep response to clonidine in depressed patients: implications for subsensitivity of alpha(2)-adrenergic receptors in depression.
    Psychiatry research, 2002, Jan-31, Volume: 109, Issue:1

    Topics: Adrenergic alpha-Agonists; Antidepressive Agents, Tricyclic; Clonidine; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Mianserin; Mirtazapine; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Sleep, REM

2002
In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs.
    Behavioural brain research, 2002, Nov-15, Volume: 136, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Clonidine; Cyclopropanes; Depression; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Swimming

2002
Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism.
    Neurology, 2003, Oct-28, Volume: 61, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Drug Administration Schedule; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Parkinsonian Disorders; Recurrence; REM Sleep Behavior Disorder; Treatment Outcome

2003
Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Clonidine; Desipramine; Dopamine; Injections, Intraperitoneal; Male; Mianserin; Microdialysis; Mirtazapine; Neurons; Norepinephrine; Occipital Lobe; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System

2004
Topiramate in opiate withdrawal- comparison with clonidine and with carbamazepine/mianserin.
    Substance abuse, 2004, Volume: 25, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Carbamazepine; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fructose; Humans; Male; Mianserin; Opioid-Related Disorders; Retrospective Studies; Substance Withdrawal Syndrome; Topiramate

2004
Comparative Evaluation of Partial α2 -Adrenoceptor Agonist and Pure α2 -Adrenoceptor Antagonist on the Behavioural Symptoms of Withdrawal after Chronic Alcohol Administration in Mice.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Alcoholism; Animals; Anxiety; Behavior, Animal; Clonidine; Depression; Dose-Response Relationship, Drug; Male; Memory; Mianserin; Mice; Mirtazapine; Receptors, Adrenergic; Substance Withdrawal Syndrome

2016