clonidine and metoprolol

clonidine has been researched along with metoprolol in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199020 (32.26)18.7374
1990's15 (24.19)18.2507
2000's17 (27.42)29.6817
2010's10 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Akamatsu, M1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Alexandre, JM; Andrejak, M; Caillens, C; Coevoet, B; de Fremont, JF; Fournier, A; Gueris, J; Harichaux, P; Lambrey, G; Makdassi, R; Quichaud, J1
Okuma, Y; Osumi, Y; Yokotani, K1
Janssen, BJ; Struyker-Boudier, HA; Tyssen, CM1
Hanin, I; Hasey, G1
Richardson, SB; Twente, S1
Chee, KY; Sachdev, P1
Koshiura, R; Miyamoto, K; Sanae, F1
Gombotz, H; Metzler, H; Rehak, P; Winkler, G1
Burdick, JF; Keown, PA; Racusen, LC; Solez, K; Vaughn, WK1
Balakumaran, K; Bokslag, M; Fels, PW; Hugenholtz, PG; Jovanovic, A; Lubsen, J; van Es, GA1
Josselson, J; Sadler, JH1
Bovenzi, F; Contursi, V; Loiacono, N; Maiorano, G; Petrelli, G; Ricapito, M1
Lopez, LM; Mehta, JL1
Hedman, C; Louis, P; Schoenen, J1
Weinshilboum, RM1
Hausen, M; Krämer, B; Kübler, W; Mäurer, W1
Johnson, JM1
Del Campo, F; Di Vincenzo, S; Ferlito, S; Fichera, C; Indelicato, G; La Vignera, A1
Silverman, MH1
Condorelli, M; Cuocolo, A; De Luca, N; De Simone, A; Ricciardelli, B; Rosiello, G; Trimarco, B; Veniero, AM; Volpe, M1
Hilakivi, I1
Johansson, G; Luostarinen, M; Virkkunen, P1
Lawson, AA; Rodrigues, E1
Freed, CR; Gerber, JG; Nies, AS1
Frick, MH; Jänne, J; Virtanen, K1
Asgeirsson, B; Berntman, L; Grände, PO; Messeter, K; Nordström, CH; Ryding, E1
Miczek, KA; Tornatzky, W1
Neuvonen, PJ; Roivas, L1
Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM1
Campos Peris, JV; de la Morena, G; García García, J; Jaén Armand, E; López Candel, J; Martínez Sánchez, J; Picó Aracil, F; Ruiz Ros, JA; Salas, J; Sánchez Muñoz, JJ1
Haass, A; Hamann, G; Schimrigk, K1
Bojö, L; Cassuto, J; Jönsson, A; Nellgård, P1
Biffi, M; Boriani, G; Branzi, A; Bronzetti, G; Frabetti, L; Magnani, B; Sabbatani, P; Zannoli, R1
Brown, J; Fee, WE; Lee, HT1
Smith, W1
Diedrich, A; Gross, V; Jordan, J; Luft, FC; Obst, M; Plehm, R; Tank, J1
Bithal, PK; Chaturvedi, A; Dash, HH; Ghosh, I; Prabhakar, H1
Friedman, GD; Habel, LA; Udaltsova, N1
Eklund, A; Hägglund, L; Koskinen, LD; Olivecrona, M; Sundström, N1

Reviews

3 review(s) available for clonidine and metoprolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome

1984
Antihypertensive pharmacology.
    The Western journal of medicine, 1980, Volume: 132, Issue:5

    Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Metoprolol; Minoxidil; Nitroprusside; Patient Compliance; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors

1980

Trials

12 trial(s) available for clonidine and metoprolol

ArticleYear
Pharmacological characterization of tardive akathisia.
    Biological psychiatry, 1990, Nov-01, Volume: 28, Issue:9

    Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztropine; Brain; Bromocriptine; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Infusions, Intravenous; Male; Metoclopramide; Metoprolol; Physostigmine; Propranolol; Psychomotor Agitation; Schizophrenia, Paranoid

1990
Intraoperative heart rate reduction--alinidine versus metoprolol.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:8

    Topics: Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Clonidine; Depression, Chemical; Double-Blind Method; Female; Heart Rate; Humans; Intraoperative Period; Male; Metoprolol; Middle Aged; Random Allocation

1988
ST 567 (alinidine) in stable angina: a comparison with metoprolol.
    European heart journal, 1987, Volume: 8 Suppl L

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Random Allocation

1987
Metoprolol v. clonidine in the prophylactic treatment of migraine.
    Cephalalgia : an international journal of headache, 1985, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Metoprolol; Migraine Disorders; Random Allocation

1985
Effect of the centrally acting agent clonidine on circulating catecholamines at rest and during exercise. Comparison with the effects of beta-blocking agents.
    Chest, 1983, Volume: 83, Issue:2 Suppl

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Physical Exertion; Propranolol; Receptors, Adrenergic, alpha; Sympathetic Nervous System

1983
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome

1984
Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension.
    Current medical research and opinion, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Xerostomia

1982
Response of blood pressure and plasma norepinephrine to propranolol, metoprolol and clonidine during isometric and dynamic exercise in hypertensive patients.
    European journal of clinical pharmacology, 1982, Volume: 21, Issue:4

    Topics: Adult; Aged; Blood Pressure; Clonidine; Exercise Test; Female; Heart Rate; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Norepinephrine; Propanolamines; Propranolol; Rest

1982
Beta-blockade in acute aneurysmal subarachnoid haemorrhage.
    Acta neurochirurgica, 1993, Volume: 121, Issue:3-4

    Topics: Adult; Aneurysm, Ruptured; Autonomic Nervous System; Clonidine; Dihydralazine; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Intracranial Aneurysm; Male; Metoprolol; Middle Aged; Prospective Studies; Subarachnoid Hemorrhage; Survival Rate

1993
Malignant vasovagal syncope: a randomised trial of metoprolol and clonidine.
    Heart (British Cardiac Society), 1997, Volume: 77, Issue:3

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Clonidine; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Single-Blind Method; Syncope, Vasovagal; Tilt-Table Test

1997
Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement.
    Journal of anesthesia, 2008, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Clonidine; Electroencephalography; Female; Heart Rate; Humans; Male; Metoprolol; Monitoring, Intraoperative; Propofol; Prospective Studies; Treatment Outcome

2008
Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.
    Neurocritical care, 2019, Volume: 31, Issue:3

    Topics: Adult; Antihypertensive Agents; Arterial Pressure; Blood Pressure; Brain; Brain Injuries, Traumatic; Cerebrovascular Circulation; Clonidine; Double-Blind Method; Epoprostenol; Erythrocyte Transfusion; Female; Fluid Therapy; Glasgow Coma Scale; Glycerol; Humans; Hypnotics and Sedatives; Intracranial Hypertension; Intracranial Pressure; Male; Metoprolol; Microdialysis; Respiration, Artificial; Thiopental; Trauma Severity Indices

2019

Other Studies

48 other study(ies) available for clonidine and metoprolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of antihypertensive drugs on dialysis-resistant hypertension, plasma renin and dopamine betahydroxylase activities, metabolic risk factors and calcium phosphate homeostasis: comparison of metoprolol, alphamethyldopa and clonidine in a cross-over t
    Clinical nephrology, 1979, Volume: 12, Issue:5

    Topics: Clonidine; Dopamine beta-Hydroxylase; Humans; Hypertension, Renal; Kidney Failure, Chronic; Methyldopa; Metoprolol; Propanolamines; Renal Dialysis; Renin; Risk

1979
Release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Butoxamine; Calcium; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Ganglionic Blockers; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Metoprolol; Norepinephrine; Perfusion; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Splanchnic Nerves; Stomach; Tetrodotoxin; Yohimbine

1992
Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Heart Rate; Hydralazine; Hypertension; Male; Metoprolol; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1991
The cholinergic-adrenergic hypothesis of depression reexamined using clonidine, metoprolol, and physostigmine in an animal model.
    Biological psychiatry, 1991, Jan-15, Volume: 29, Issue:2

    Topics: Acetylcholine; Animals; Brain; Clonidine; Depressive Disorder; Male; Metoprolol; Models, Biological; Neostigmine; Norepinephrine; Physostigmine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Cholinergic

1991
Inhibition of hypothalamic somatostatin release by beta-adrenergic antagonists.
    Endocrinology, 1990, Volume: 126, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Clonidine; Growth Hormone; Hypothalamus; Labetalol; Male; Metoprolol; Ouabain; Pituitary Gland, Anterior; Propranolol; Rats; Rats, Inbred Strains; Somatostatin

1990
Altered adrenergic response and specificity of the receptors in rat ascites hepatoma AH130.
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: Adenylyl Cyclases; Albuterol; Animals; Cell Line; Clonidine; Enzyme Activation; Epinephrine; Iodocyanopindolol; Isoproterenol; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Metoprolol; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tumor Cells, Cultured

1989
The influence of antihypertensive drug therapy on renal transplant function and outcome.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Antihypertensive Agents; Clonidine; Creatinine; Cyclosporins; Graft Rejection; Humans; Kidney; Kidney Transplantation; Metoprolol; Nifedipine; Propranolol

1988
Nephrotic-range proteinuria and hyperglycemia associated with clonidine therapy.
    The American journal of medicine, 1986, Volume: 80, Issue:3

    Topics: Aged; Clonidine; Drug Synergism; Glycosuria; Humans; Hyperglycemia; Insulin; Male; Metoprolol; Proteinuria

1986
[Clinico-therapeutic evaluation of the hypertensive patient by the isometric exertion test].
    Minerva cardioangiologica, 1986, Volume: 34, Issue:3

    Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Clonidine; Female; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Muscle Contraction

1986
Rebound hypertension following abrupt cessation of clonidine and metoprolol. Treatment with labetalol.
    Archives of internal medicine, 1987, Volume: 147, Issue:2

    Topics: Aged; Clonidine; Humans; Hypertension; Labetalol; Male; Metoprolol; Substance Withdrawal Syndrome

1987
Antihypertensive drugs that alter adrenergic function.
    Mayo Clinic proceedings, 1980, Volume: 55, Issue:6

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System

1980
Blood glycerol levels in type-2 diabetics after beta-1-blockade and alpha-2 adrenergic stimulation.
    Il Farmaco; edizione pratica, 1984, Volume: 39, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Clonidine; Diabetes Mellitus, Type 2; Female; Glucagon; Glycerol; Humans; Male; Metoprolol; Middle Aged

1984
Polyarteritis nodosa associated with ulcerative colitis.
    The Journal of rheumatology, 1984, Volume: 11, Issue:3

    Topics: Adolescent; Clonidine; Colectomy; Colitis, Ulcerative; Cyclophosphamide; Humans; Hypertension; Ileostomy; Male; Metoprolol; Minoxidil; Polyarteritis Nodosa; Prednisone

1984
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
    Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:8

    Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methyldopa; Metoprolol; Middle Aged

1983
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
    Brain research, 1983, Oct-24, Volume: 277, Issue:1

    Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages

1983
Diazepam, alpha and beta neurotransmission modifying drugs and contrast media mortality in mice.
    Acta radiologica: diagnosis, 1984, Volume: 25, Issue:3

    Topics: Animals; Clonidine; Diatrizoate; Diatrizoate Meglumine; Diazepam; Drug Interactions; Female; Lethal Dose 50; Male; Metoprolol; Mice; Phentolamine; Prazosin; Propranolol; Sympatholytics; Sympathomimetics

1984
Effects of hypotensive treatment with alpha 2-agonist and beta 1-antagonist on cerebral haemodynamics in severely head injured patients.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:3

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Cerebrovascular Circulation; Clonidine; Craniocerebral Trauma; Female; Hemodynamics; Humans; Intracranial Pressure; Male; Metoprolol; Middle Aged

1995
Behavioral and autonomic responses to intermittent social stress: differential protection by clonidine and metoprolol.
    Psychopharmacology, 1994, Volume: 116, Issue:3

    Topics: Agonistic Behavior; Animals; Anxiety; Autonomic Nervous System; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Drug Implants; Female; Heart Rate; Male; Metoprolol; Motor Activity; Norepinephrine; Rats; Social Behavior; Stress, Psychological; Vocalization, Animal

1994
Drug adsorption onto activated charcoal as a means of formulation.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:5

    Topics: Adsorption; Albuterol; Charcoal; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Clonidine; Furosemide; Kinetics; Metoprolol; Pindolol; Sympatholytics

1994
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
    Chronobiology international, 1993, Volume: 10, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes

1993
[Malignant vasovagal syncope: its diagnosis and therapeutic trial based on the orthostatism test (the tilt-table test)].
    Revista espanola de cardiologia, 1993, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Clonidine; Female; Heart Function Tests; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Posture; Recurrence; Scopolamine; Syncope

1993
Influence of adrenoceptor agonists and antagonists on fluid secretion in small bowel obstruction.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:11

    Topics: Adrenergic Agonists; Adrenergic Antagonists; Albuterol; Analysis of Variance; Animals; Body Water; Clonidine; Intestinal Obstruction; Intestine, Small; Jejunal Diseases; Male; Metoprolol; Phenylephrine; Prazosin; Prenalterol; Rats; Rats, Sprague-Dawley; Yohimbine

1995
Baroreflex dysfunction after nasopharyngectomy and bilateral carotid isolation.
    Archives of otolaryngology--head & neck surgery, 1997, Volume: 123, Issue:4

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Baroreflex; Blood Pressure; Carcinoma, Squamous Cell; Carotid Artery, Internal; Clonidine; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Otolaryngology; Pharyngectomy; Postoperative Complications; Sympatholytics

1997
Malignant vasovagal syncope: a randomised trial of metoprolol and clonidine.
    Heart (British Cardiac Society), 1998, Volume: 79, Issue:1

    Topics: Adrenergic beta-Agonists; Antihypertensive Agents; Clonidine; Humans; Isoproterenol; Metoprolol; Syncope, Vasovagal; Tilt-Table Test

1998
Clonidine improves spontaneous baroreflex sensitivity in conscious mice through parasympathetic activation.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Baroreflex; Blood Pressure; Clonidine; Consciousness; Heart Rate; Male; Metoprolol; Mice; Monitoring, Physiologic; Parasympathetic Nervous System; Respiration; Species Specificity; Sympathetic Nervous System; Telemetry; Yohimbine

2004
Norepinephrine antagonists and cancer risk.
    International journal of cancer, 2011, Feb-01, Volume: 128, Issue:3

    Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment

2011