clonidine and metoclopramide

clonidine has been researched along with metoclopramide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's7 (23.33)18.2507
2000's11 (36.67)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Groszmann, RJ; Rodríguez-Pérez, F1
Chee, KY; Sachdev, P1
Ikeda, M; Koshida, H; Matsubara, T; Miyamori, I; Okamoto, S; Soma, R; Takeda, R1
Hashimoto, H; Hasui, M; Igarashi, N; Kato, E; Minami, S; Okabe, T; Sato, T1
Cooper, SM; McRitchie, B1
Baranowska, B; Jeske, W; Nowakowski, J; Singh, SP; Soszynski, P1
Christensen, NJ; Eldrup, E; Hagen, C; Olgaard, K1
Borsini, F; Nowakowska, E; Samanin, R1
Spedding, M1
Hurtado, E; Lanes, R1
Fenton, HM; Liebman, JM1
Schirger, A; Schwartz, GL1
LaPointe, J; Slavik, KJ1
Amorosi, A; Credi, G; Ianni, L; Lanzillotti, R; Mannelli, M; Pratesi, C; Pupilli, C1
Hall, JE; Martin, KA; Perkins, RB1
Castagné, V; Goineau, S; Guillaume, P1

Reviews

2 review(s) available for clonidine and metoclopramide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic treatment of portal hypertension.
    Gastroenterology clinics of North America, 1992, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Metoclopramide; Molsidomine; Nitrates; Nitroglycerin; Serotonin Antagonists; Somatostatin; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins

1992

Trials

2 trial(s) available for clonidine and metoclopramide

ArticleYear
Pharmacological characterization of tardive akathisia.
    Biological psychiatry, 1990, Nov-01, Volume: 28, Issue:9

    Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztropine; Brain; Bromocriptine; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Infusions, Intravenous; Male; Metoclopramide; Metoprolol; Physostigmine; Propranolol; Psychomotor Agitation; Schizophrenia, Paranoid

1990
Neuroendocrine abnormalities in hypothalamic amenorrhea: spectrum, stability, and response to neurotransmitter modulation.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:6

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Amenorrhea; Clonidine; Dopamine Antagonists; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypothalamic Diseases; Longitudinal Studies; Luteinizing Hormone; Metoclopramide; Naloxone; Narcotic Antagonists; Neurosecretory Systems; Neurotransmitter Agents; Sleep

1999

Other Studies

26 other study(ies) available for clonidine and metoclopramide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Evaluation of clonidine suppression and various provocation tests in the diagnosis of pheochromocytoma.
    Journal of endocrinological investigation, 1990, Volume: 13, Issue:10

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Blood Pressure; Clonidine; Epinephrine; Female; Glucagon; Humans; Kinetics; Male; Metoclopramide; Middle Aged; Naloxone; Norepinephrine; Pheochromocytoma

1990
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
    Acta endocrinologica, 1988, Volume: 117, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinoprostone; Dopamine; Epinephrine; Female; Humans; Hypertension; Indomethacin; Levodopa; Metoclopramide; Norepinephrine; Periodicity; Prostaglandins E; Psychotic Disorders; Recurrence; Syndrome; Vomiting

1988
Role of dopamine and alpha-adrenoreceptors in the control of gastric emptying in the rat: possible involvement in the mechanism of action of metoclopramide.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Gastric Emptying; Male; Metoclopramide; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Tetrahydronaphthalenes

1985
The role of opiate, dopaminergic, and adrenergic systems in the hypothalamo-pituitary dysfunction in obesity.
    Acta endocrinologica, 1987, Volume: 116, Issue:2

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; beta-Endorphin; Clonidine; Female; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Metoclopramide; Naloxone; Obesity; Prolactin; Receptors, Dopamine; Receptors, Opioid

1987
Plasma free and sulfoconjugated dopamine in man: relationship to sympathetic activity, adrenal function and meals.
    Danish medical bulletin, 1988, Volume: 35, Issue:3

    Topics: Adrenal Glands; Adult; Clonidine; Dopamine; Food; Humans; Male; Metoclopramide; Middle Aged; Receptors, Dopamine; Sulfates; Sympathetic Nervous System

1988
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
    Life sciences, 1984, Mar-19, Volume: 34, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride

1984
Effects of metoclopramide and isoprenaline in the rat vas deferens; interactions with alpha-adrenoceptors.
    British journal of pharmacology, 1980, Volume: 71, Issue:1

    Topics: Animals; Benzamides; Clonidine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens

1980
Oral clonidine-an effective growth hormone-releasing agent in prepubertal subjects.
    The Journal of pediatrics, 1982, Volume: 100, Issue:5

    Topics: Administration, Oral; Adolescent; Blood Glucose; Child; Clonidine; Female; Growth Hormone; Humans; Hydrocortisone; Insulin; Male; Metoclopramide; Puberty

1982
Self-stimulation response decrement patterns differentiate clonidine, baclofen and dopamine antagonists from drugs causing performance deficit.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6

    Topics: Animals; Baclofen; Clonidine; Conditioning, Operant; Dopamine Antagonists; Extinction, Psychological; Haloperidol; Male; Methocarbamol; Metoclopramide; Prazosin; Rats; Rats, Inbred F344; Receptors, Dopamine; Self Stimulation

1982
Orthostatic hypotension.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Cerebrovascular Circulation; Clonidine; Deamino Arginine Vasopressin; Dihydroergotamine; Dopamine; Epinephrine; Humans; Hypotension, Orthostatic; Metoclopramide; Octreotide; Patient Education as Topic; Pindolol; Yohimbine

1994
Involvement of inhibitory dopamine-2 receptors in resting bradycardia in exercise-conditioned rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Bromocriptine; Clonidine; Female; Heart Rate; Metoclopramide; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Yohimbine

1993
A nonsecreting pheochromocytoma presenting as an incidental adrenal mass. Report on a case.
    Journal of endocrinological investigation, 1993, Volume: 16, Issue:10

    Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Catecholamines; Clonidine; Female; Glucagon; Heart Rate; Humans; Immunohistochemistry; Male; Metoclopramide; Pheochromocytoma; Tomography, X-Ray Computed; Tyramine

1993
Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1

    Topics: Acetaminophen; Animals; Clonidine; Gastric Emptying; Gastric Mucosa; Intestine, Small; Loperamide; Male; Metoclopramide; Phenolsulfonphthalein; Rats; Rats, Wistar

2015