clonidine has been researched along with methyldopa in 321 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 275 (85.67) | 18.7374 |
| 1990's | 23 (7.17) | 18.2507 |
| 2000's | 12 (3.74) | 29.6817 |
| 2010's | 10 (3.12) | 24.3611 |
| 2020's | 1 (0.31) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hayduk, K | 1 |
| Kellaway, GS | 1 |
| Clineschmidt, BV; Scriabine, A; Sweet, CS | 1 |
| Petrie, JC | 1 |
| Michel, D | 1 |
| DeStevens, G; Wilhelm, M | 1 |
| Nies, AS | 1 |
| Black, HR | 1 |
| Goldberg, AD; Raftery, EB; Wilkinson, P | 1 |
| Oparil, S; Rick, JH | 1 |
| Andrejak, M; Coevoet, B; De Fremont, JF; Fournier, A; Hardin, JM; Lambrey, G; Quichaud, J | 1 |
| Dal Palù, C; Pessina, AC; Pigato, R | 1 |
| Redman, CW | 1 |
| Gifford, RW; Tarazi, RC; Wollam, GL | 1 |
| Klien, W | 1 |
| Edmondson, RP; Hilton, PJ; Jones, NF; Thomas, RD | 1 |
| Havard, CW; Pearson, RM | 1 |
| Baietti, M; Carletta, C; Liuti, G; Mancinella, A; Paolucci, M | 1 |
| Kuchel, OG; Mahon, WA; McKenzie, JK; Ogilvie, RI | 1 |
| Hammond, JJ; Kirkendall, WM | 1 |
| Israili, ZH | 1 |
| Henning, M | 2 |
| Elghozi, JL; Grünfeld, JP; Meyer, P | 1 |
| Chu, D; Hofmann, A; Stürmer, E | 1 |
| Ozaki, M | 1 |
| Walters, WA | 1 |
| Enenkel, W | 1 |
| Cybulska, I | 1 |
| Armbruster, H; Beckerhoff, R; Reck, G; Siegenthaler, W; Vetter, W | 1 |
| Dixon, GT; Johnson, ES | 1 |
| Sternon, J | 2 |
| McDevitt, DG | 1 |
| Kobinger, W | 1 |
| van Zwieten, AP | 1 |
| Langer, SZ | 1 |
| Boudier, HS; Brouwer, G; Smeets, G; van Rossum, J | 1 |
| Mills, LC | 1 |
| Fang, P; Hua, A; Kincaid-Smith, P; Laver, MC; Macdonald, IM | 1 |
| Birkenhäger, WH; Rotterdam, T | 1 |
| Smith, AJ | 1 |
| Dengler, HJ; Hengstmann, JH | 1 |
| Romankiewicz, JA | 1 |
| Rodman, MJ | 1 |
| Moses, C | 1 |
| Riddiough, MA | 1 |
| Schumacher, GE | 1 |
| Distler, A | 1 |
| Spence, JD | 1 |
| Bravkov, MF | 1 |
| de Schepper, J; van Bogaert, A | 1 |
| Kuokkanen, K; Mattila, MJ | 1 |
| Ishii, H; Nakamura, K; Okada, T | 2 |
| Alexandre, JM; Andrejak, M; Caillens, C; Coevoet, B; de Fremont, JF; Fournier, A; Gueris, J; Harichaux, P; Lambrey, G; Makdassi, R; Quichaud, J | 1 |
| Block, HU; Förster, W; Taube, C | 1 |
| Albano, V; Bellanca, L; Latteri, S; Valdes, L | 1 |
| De Thomatis, M; Falciola, N; Gallesio, R; Montevecchi, A | 1 |
| Bhargava, KP; Gupta, NN; Hasan, M; Kishor, K; Sahuja, RC; Saran, RK; Shanker, K | 1 |
| Kaukinen, S; Ylitalo, P | 1 |
| Evans, GT; Massie, B; Ryan, C; Scheinman, MM; Strauss, HC; Wallace, A | 1 |
| Sandifer, MG | 1 |
| Kaukinen, S | 2 |
| Finnerty, FA | 3 |
| Dunemann, A; Förster, W; Hauser, A; Taube, C | 1 |
| Genest, J; Guthrie, GP; Kuchel, O | 1 |
| Bianchi, G; Bielli, M; Folli, G; Romeo, PB; Vitolo, E | 1 |
| Corvol, PL; London, GM; Menard, JE; Milliez, PL; Safar, ME; Weiss, YA | 1 |
| Bateman, FJ; Curtis, JR | 1 |
| White, RP | 1 |
| Denkl, P; Haas, Th | 1 |
| Grenfell, RF | 1 |
| van Zwieten, PA | 4 |
| Aboras, NE; Lelguen, CE; Milliez, PM; Roland, EQ; Safar, ME; Weiss, YA | 1 |
| Gessler, U; Pilgrim, R | 1 |
| Gaul, SL; Sweet, CS | 1 |
| Engelking, H | 1 |
| Gilbert, JC | 1 |
| Cottier, P; Seiler, A | 1 |
| Block, HU; Förster, W; Heinroth, I; Mentz, P; Pönicke, K; Taube, C | 1 |
| Angelino, PF | 1 |
| Lavezzaro, G | 1 |
| Biale, A; Castelluccio, A; Gatti, C; Ghersi, G; Rondelli, E; Stella, G | 1 |
| Hlede, M; Palatini, P; Pessina, AC; Pigato, R | 1 |
| Dollery, CT | 1 |
| Zwieten, PA | 1 |
| Haeusler, G | 1 |
| Chidsey, CA; Gottlieb, TB | 1 |
| Alexander, CP; Lavin, P | 1 |
| Block, HU; Föster, W; Taube, C | 1 |
| Kosman, ME | 1 |
| Maronde, RF | 1 |
| Block, HU; Förster, W; Mest, HJ; Taube, C | 1 |
| Mundy, GR; Raisz, LG | 1 |
| Fujita, T; Ono, A | 1 |
| Miller, KL | 1 |
| Head, GA | 1 |
| Carlsson, A; Carlsson, M; Svensson, A | 1 |
| Bhandare, PN; D'Souza, RS; Rataboli, PV | 1 |
| Aslanian, V; Chalmers, J; Drolet, G; Minson, J; Morris, M | 1 |
| Clark, DW; Curzio, JL; Howie, CA; Reid, JL | 1 |
| Babaian, AS; Dzhandzhapanian, AZ; Gurgenian, SV; Mikaelian, ES | 1 |
| Epstein, M; Oster, JR | 1 |
| Johnston, GD; Smith, AM | 1 |
| Mathias, CJ | 1 |
| Christensen, HD; Koss, MC; Mutzig, M | 1 |
| MacLeod, SM; Manmontri, A | 1 |
| Dakshinamurti, K; Paulose, CS; Viswanathan, M | 1 |
| Mehta, VL; Prabhu, S; Valecha, N | 1 |
| Gehr, M; Goldberg, M | 1 |
| Kaplan, NM | 1 |
| Pandhi, P; Sharma, PL | 1 |
| Cubeddu, LX; Hoffman, IS | 1 |
| Anderson, CR; Elghozi, JL; Head, GA; Korner, PI; Wolf, WA | 1 |
| Coghlan, JP; Mathai, M; Mills, EH; Scoggins, BA; Spence, CD; Whitworth, JA | 1 |
| Deschamps de Paillette, E; Grimberg, D; Tarrade, T | 1 |
| Batts, J; Branche, G; Brown, J; Dowdy, V; King, A; Streets, M | 1 |
| Cerný, J; Dolezel, S; Dostál, M; Guba, P; Petrzilka, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Weber, MA | 1 |
| Cerný, J; Dostál, M; Gregor, Z; Guba, P; Rebícek, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Olevskiĭ, IKh; Teĭblium, MM; Varshitskiĭ, MG; Vilkovyskiĭ, FA; Zaslavskaia, RM | 1 |
| Berkowitz, RL; Chervenak, FA | 1 |
| van der Meer, C | 1 |
| Motz, W; Strauer, BE | 1 |
| Smith, PJ; Talbert, RL | 1 |
| Hany, S; Predel, G; Stimpel, M | 1 |
| Giles, TD; Quiroz, AC; Sander, GE; Thomas, MG | 1 |
| Badoer, E; Head, GA; Korner, PI | 1 |
| Conway, EL; Jarrott, B; Louis, WJ | 1 |
| Hayashi, T; Nakajima, T; Nakamura, K | 1 |
| Peart, S | 1 |
| Mirmiran, M | 1 |
| Child, A; Henderson-Smart, DJ; Horvath, JS; Korda, A; Phippard, A; Tiller, DJ | 1 |
| Evans, WS; Ho, KY; Thorner, MO | 1 |
| Adams, EF; Brown, MJ; Dollery, CT; Struthers, AD | 1 |
| Brunner, HR; Nussberger, J; Waeber, B | 1 |
| Child, A; Duggin, GG; Hall, BM; Henderson-Smart, D; Horvath, JS; Korda, A; Phippard, A; Tiller, DJ | 1 |
| Bonomo, P; Cherchi, A; Mercuro, G; Sau, F; Seguro, C | 1 |
| Tuckman, J; Vorburger, C | 1 |
| Schneider, KW | 1 |
| Almeyda, J; Levantine, A | 1 |
| Kincaid-Smith, P | 2 |
| Alexandre, JM; Ménard, J; Milliez, P | 1 |
| Baglin, A; Fritel, D | 1 |
| Fournier, A; Lagrue, G; Schmitt, H | 2 |
| Bloch-Laine, JF; Corvol, P; Menard, J; Milliez, P | 1 |
| Simpson, FO | 2 |
| Trocme, C | 1 |
| Perrier, CV; Sitavanc, L | 1 |
| Rahn, KH | 1 |
| Nast, HP; Philipp, T | 1 |
| Buisson, C; Lagrue, G; Weil, B | 1 |
| Bauer, GE | 1 |
| Gifford, RW | 1 |
| McNay, JL | 1 |
| Brunner, HR | 1 |
| Vidt, DG | 1 |
| Senault, B | 1 |
| Laverty, R | 1 |
| Alexandre, JM; Corvol, P; Ménard, J; Milliez, P | 1 |
| Bolme, P; Fuxe, K; Lidbrink, P | 1 |
| Linde, I; Poppelbaum, HF; Rüdiger, H | 1 |
| Poyser, RH; Shorter, JH; Whiting, RL | 1 |
| Helber, A; Kaufmann, W | 1 |
| Dufey, K; Krönig, B | 1 |
| Ambrosioni, E; Costa, V; Magnani, B | 1 |
| Dhasmana, KM; Fokker, WA; Spilker, BA | 1 |
| Finnerty, FA; Leibel, BA; Mroczek, WJ | 1 |
| Amery, AK; Bossaert, H; Fagard, RH; Verstraete, M | 1 |
| Vorburger, C | 1 |
| Lung-Johansen, P | 1 |
| Anlauf, M; Hampel, R; Hoersen, H; Merguet, P | 1 |
| Abernethy, JD | 1 |
| Torsti, P | 1 |
| Andén, NE; Engel, J | 1 |
| Elliott, RW; Kerr, DN; Pickering, M; Robson, V; Wilkinson, R | 1 |
| Milliez, P; Safar, M | 1 |
| Pieri, R; Pirrelli, A | 1 |
| Reubi, F | 1 |
| Baglin, A; Merceron, R; Milliez, P; Safar, M; Sobel, A | 1 |
| Andén, NE; Strömbom, U; Svensson, TH | 1 |
| Bauer, GE; Lewis, RG; Maclachlan, I; Mitchell, AS; Raftos, J; Stokes, GS; Young, AA | 1 |
| Rorive, G | 1 |
| Froment, A; Milon, H | 1 |
| Matts, SG | 1 |
| Hashida, J | 1 |
| Khlebarova, M; Kiriakov, A; Panova, I; Staneva-Stoicheva, D | 1 |
| Corvol, P; Folliot, A; Ménard, J; Safar, M; Weiss, Y | 1 |
| Kishimoto, M | 1 |
| Hoobler, SW; Putzeys, MR | 1 |
| Storm-Mathisen, H | 1 |
| Gehr, M; Goldberg, M; MacCarthy, EP | 1 |
| Drayer, JI; Weber, MA | 2 |
| Farsang, C; Kunos, G; Newman, F; Ungar, W | 1 |
| de Jong, W; Head, GA | 1 |
| Doyle, AE | 1 |
| Mashford, ML | 1 |
| Weinshilboum, RM | 1 |
| Bullen, MU | 1 |
| Hubbell, FA; Weber, MA | 1 |
| Moodley, J | 1 |
| Halawa, B | 1 |
| Bravkov, MF; Tsyrlin, VA | 1 |
| Fossati, C | 1 |
| Scapellato, L; Stornello, M | 1 |
| Korn, A | 1 |
| Houston, MC | 3 |
| Marxer, A; Schier, O | 1 |
| Fleminger, R; Paykel, ES; Watson, JP | 1 |
| Oparil, S | 1 |
| Matricardi, L; Selmi, W | 1 |
| Lund-Johansen, P | 1 |
| Cummings, DM; Vlasses, PH | 1 |
| Richter, R | 1 |
| Koller, H; Prager, H | 1 |
| Gerold, M; Haeusler, G | 1 |
| Wallin, JD | 1 |
| Zier, BG | 1 |
| Stevenson, JG; Umstead, GS | 1 |
| Johnson, JM | 1 |
| Ruffolo, RR | 1 |
| Moyer, JH | 2 |
| Beeley, L | 1 |
| Timmermans, PB; Van Brummelen, P; Van Zwieten, PA | 1 |
| Prichard, BN | 1 |
| Zabetakis, PM | 1 |
| Bartay, J; Benson, D; Peterson, LG | 1 |
| Geromino, A; Ghergo, GF; Giosuè, G; Negri, L; Tubaldi, A | 1 |
| Condorelli, M; Cuocolo, A; De Luca, N; De Simone, A; Ricciardelli, B; Rosiello, G; Trimarco, B; Veniero, AM; Volpe, M | 1 |
| Dunlap, WP; Harston, CT; Hennig, CW; Macphee, AA | 1 |
| Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD | 1 |
| Clineschmidt, BV; Faison, EP; Flataker, LM; Haubrich, DR | 1 |
| Gerkens, JF; Goldberg, MR; Oates, JA; Robertson, D | 1 |
| Timmermans, PB; van Zwieten, PA | 1 |
| Elliott, HL; McLean, K; Reid, JL; Sumner, DJ | 1 |
| Kunos, G; Mosqueda Garcia, R; Ramirez-Gonzalez, MD; Tchakarov, L | 1 |
| Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG | 1 |
| Conway, EL; Jarrott, B; Lewis, S; Louis, WJ; Summers, R | 1 |
| Oide, M | 1 |
| Dackis, CA; Gold, MS; Washton, AM | 1 |
| Frohlich, ED; Ishise, S; Pegram, BL | 2 |
| Goldberg, MR; Robertson, D; Tung, CS | 1 |
| Celuch, SM; Enero, MA; Taira, CA | 1 |
| Eninia, GI; Godlevska, MA; Smeltere, ES; Uzulinia, IP | 1 |
| Affrime, MB; Falkner, B; Hakki, H; Lowenthal, DT; Rosenthal, L; Saris, S | 1 |
| Dovgalevskiĭ, PIa; Khalfen, ESh; Korsh, BS; Pankova, GF | 1 |
| Brunetti, P; Fedeli, L; Filipponi, P; Nicoletti, I; Palumbo, R; Santeusanio, F; Santori, P | 1 |
| Whitsett, TL | 1 |
| Elliott, HL; Reid, JL; Whiting, B | 1 |
| Pearlman, C | 1 |
| Harris, DB; Stiff, JL | 1 |
| Kirschenbaum, HL; Rosenberg, JM | 1 |
| Barrow, CG; O'Halloran, MW; Wilson, LL; Zacest, R | 1 |
| Berkowitz, RL | 1 |
| Freed, CR; Gerber, JG; Nies, AS | 1 |
| Segal, JL | 1 |
| Reisman, L; Selden, RV | 1 |
| Feldman, RD; Goldberg, MR; Oates, JA; Robertson, D; Smith, HE; Tung, CS | 1 |
| Caris, TN | 1 |
| Gerkens, JF; Goldberg, MR; Oates, JA; Ring, M; Robertson, D; Tung, CS | 1 |
| Moss, HB; Procci, WR | 1 |
| Hayashi, T; Nakamura, K | 1 |
| Baum, T; Moran, RM; Sabin, C | 1 |
| Greenberg, S | 1 |
| Anderson, S; Cronin, R; Henrich, WL; Mitchell, H; Pettinger, WA | 1 |
| Béroniade, V | 1 |
| Lochaya, S; Suvachittanont, O; Thongmitr, V | 1 |
| Benevent, D; Charmes, JP; Leroux-Robert, C; Rince, M | 1 |
| Gavras, H; Gavras, I | 1 |
| Dal Palù, C; Hlede, M; Palatini, P; Pessina, AC; Pigato, R | 1 |
| Guerrera, G; Melina, D | 1 |
| Shapiro, AP; Traub, YM | 1 |
| Head, GA; Korner, PI; Van den Buuse, M | 1 |
| Godwin, SJ; Head, GA; Sannajust, F | 1 |
| Castro, RM; Cunha, SP; França, LC; Nagata, NY | 1 |
| Ferner, RE; Lip, GY; Zarifis, J | 1 |
| Koch, HF; Webster, J | 1 |
| Kawasaki, H | 1 |
| Frohlich, ED; Ishize, S; Pegram, BL | 1 |
| Agrawal, YK; Majumdar, F | 1 |
| Correia, ML; de Lemos Neto, M; de Oliveira, LF; Resende, AC; Rios, AA; Santos, EJ; Soares de Moura, R; Tano, T | 1 |
| Fekete, MI; Fülöp, F; Homicskó, KG; Kertész, I; Nagy, GM; Radnai, B; Tóth, BE; Tóth, G | 1 |
| Hirai, S | 1 |
| Takishita, S; Yamazato, M | 1 |
| Barton, D; Loprinzi, CL; Stearns, V | 1 |
| Sica, DA | 1 |
| Bakan, E; Borekci, B; Kumbasar, S; Kumtepe, Y; Salman, S; Suleyman, H; Yilmaz, M | 1 |
| Black, HR; Slim, HB; Thompson, PD | 1 |
| Charlton, F; Hennessy, A; Makris, A; Xu, B | 1 |
| Bobek, G; Hennessy, A; Makris, A; Xu, B | 1 |
| Mar, PL; Raj, SR | 1 |
77 review(s) available for clonidine and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Management of high blood pressure using beta-sympatholytics. Review].
Topics: Adrenergic beta-Antagonists; Clonidine; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Spironolactone | 1976 |
Antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Blood Vessels; Clonidine; Diuretics; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; History, 20th Century; Hydralazine; Methyldopa; Monoamine Oxidase Inhibitors; Muscle, Smooth; Renin; Reserpine; Sympathetic Nervous System; Vasodilator Agents; Water-Electrolyte Balance | 1976 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blood Pressure; Clonidine; Diazoxide; Diuretics; Emergencies; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Prazosin; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Trimethaphan | 1977 |
The use of antihypertensive drugs in hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Drug Therapy, Combination; Eclampsia; Female; Humans; Hydralazine; Hypertension; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Reserpine; Sodium Chloride Symporter Inhibitors | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Potassium; Prazosin; Secologanin Tryptamine Alkaloids; Sympatholytics | 1977 |
[Etiology, pathogenesis and epidemiology of hypertension].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Benzothiadiazines; Cardiac Output; Clonidine; Diuretics; Drug Evaluation; Haplorhini; Heart Rate; Hemodynamics; Humans; Hypertension; Methyldopa; Middle Aged; Prazosin; Rats; Sodium Chloride; Sodium Chloride Symporter Inhibitors; Stress, Psychological | 1978 |
Central alpha-adrenergic systems as targets for hypotensive drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Clonidine; Depression, Chemical; Hemodynamics; Methyldopa; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
Correlation of pharmacological effects with plasma levels of antihypertensive drugs in man.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Guanethidine; Humans; Hypertension; Kinetics; Methyldopa; Reserpine; Vasodilator Agents | 1979 |
[Pharmacology of centrally active antihypertensive agents (author's transl)].
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Humans; Methyldopa; Rats; Reserpine; Serotonin; Structure-Activity Relationship | 1979 |
[Cardiac therapy in the old patient].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycosides; Diuretics; Dose-Response Relationship, Drug; Drug Tolerance; Glomerular Filtration Rate; Heart Diseases; Heart Failure; Humans; Hypertension; Isosorbide Dinitrate; Kidney; Methyldopa; Middle Aged; Nitroglycerin; Prazosin; Reserpine; Water-Electrolyte Balance | 1979 |
[Antihypertensive drugs acting through neurogenic mechanisms].
Topics: Animals; Antihypertensive Agents; Brain; Clonidine; Hypertension; Methyldopa; Rabbits; Receptors, Adrenergic, beta | 1977 |
[Influence of antihypertensive agents on catecholamine and metabolite excretion and its significance for the diagnosis of pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Clonidine; Diuretics; Epinephrine; Guanethidine; Guanidines; Humans; Methyldopa; Norepinephrine; Pheochromocytoma; Reserpine | 1975 |
Preventing, detecting and managing adverse reactions of antihypertensive agents in the ambulant patient with essential hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone | 1977 |
Using pharmacokinetics in drug therapy. V: Contributions to developing dosage regimens for antihypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Drug Administration Schedule; Guanethidine; Humans; Hydralazine; Kinetics; Methyldopa; Minoxidil; Prazosin; Propranolol | 1979 |
[The sympathetic nervous system and essential hypertension].
Topics: Atenolol; Catecholamines; Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Vanilmandelic Acid | 1979 |
Renin and the therapy of hypertension.
Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Clonidine; Diazoxide; Diuretics; Dogs; Female; Guanethidine; Humans; Hypertension; Male; Methyldopa; Propranolol; Renin; Reserpine; Spironolactone; Vasodilator Agents | 1976 |
Central sympathetic transmitters and hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Dogs; Heart Rate; Humans; Hypertension; Methyldopa; Nordefrin; Norepinephrine; Rabbits; Rats; Serotonin | 1975 |
Cardiovascular regulation by central adrenergic mechanisms and its alteration by hypotensive drugs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Mapping; Brain Stem; Cardiovascular System; Cats; Clonidine; Disease Models, Animal; Electric Stimulation; Epinephrine; Evoked Potentials; Hydroxydopamines; Hypertension; Hypothalamus; Hypothalamus, Posterior; Methyldopa; Neural Inhibition; Neural Pathways; Pressoreceptors; Rabbits; Rats; Receptors, Adrenergic; Sympathetic Nervous System | 1975 |
The clinician's guide to pharmacology of antihypertensive agents.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Kinetics; Methyldopa; Reserpine; Sympathetic Nervous System | 1976 |
Alternatives to estrogen for menopausal symptoms.
Topics: Adult; Androgens; Climacteric; Clonidine; Estrogen Replacement Therapy; Female; Humans; Methyldopa; Middle Aged; Progestins; Risk Factors | 1992 |
Use of centrally acting sympatholytic agents in the management of hypertension.
Topics: Aged; Clonidine; Guanfacine; Heart; Humans; Hypertension; Kidney; Methyldopa; Sympatholytics | 1991 |
Management of overdose due to antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diuretics; Humans; Methyldopa; Poisoning | 1990 |
Management of hypertension by reduction in sympathetic activity.
Topics: Behavior Therapy; Blood Pressure; Body Weight; Clonidine; Humans; Hypertension; Methyldopa; Sympathetic Nervous System | 1991 |
Centrally acting sympatholytic agents in the treatment of congestive heart failure. A review of the literature.
Topics: Bromocriptine; Clinical Trials as Topic; Clonidine; Guanabenz; Heart Failure; Humans; Methyldopa; Sympatholytics | 1990 |
Cerebrospinal fluid norepinephrine levels in essential hypertension: effects of drug treatment and withdrawal.
Topics: Adult; Clonidine; Dopamine; Double-Blind Method; Epinephrine; Humans; Hypertension; Methyldopa; Middle Aged; Norepinephrine; Propranolol; Random Allocation | 1987 |
Clinical pharmacology of centrally acting antihypertensive agents.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Guanfacine; Guanidines; Humans; Hypertension; Methyldopa; Phenylacetates; Risk Factors | 1989 |
Hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Clonidine; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Sheep; Sympathetic Nervous System; Vasodilator Agents | 1985 |
Sexual dysfunction with antihypertensive and antipsychotic agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Antipsychotic Agents; Benzothiadiazines; Calcium Channel Blockers; Clonidine; Diuretics; Ejaculation; Female; Guanethidine; Humans; Male; Methyldopa; Orgasm; Penile Erection; Prazosin; Reserpine; Sexual Dysfunction, Physiological; Sodium Chloride Symporter Inhibitors; Spironolactone | 1986 |
Disorders of prolactin and growth hormone secretion.
Topics: Acromegaly; Arginine; Clonidine; Dwarfism; Female; Glucose Tolerance Test; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Insulin-Like Growth Factor I; Kidney Failure, Chronic; Lactation; Levodopa; Male; Methyldopa; Physical Exertion; Pituitary Neoplasms; Pregnancy; Prolactin; Propranolol; Reserpine; Sleep; Somatomedins; Thyrotropin-Releasing Hormone | 1985 |
[Drug therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Chemical Phenomena; Chemistry; Clonidine; Diuretics; Drug Combinations; Ganglionic Blockers; Guanethidine; Humans; Hypertension; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Secologanin Tryptamine Alkaloids | 1973 |
Cutaneous reactions to cardiovascular drugs.
Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Debrisoquin; Digitalis Glycosides; Drug Eruptions; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Mercury; Methyldopa; Nitroglycerin; Pentaerythritol Tetranitrate; Procainamide; Quinidine; Thiazines | 1973 |
The central action of antihypertensive drugs, mediated via central alpha-receptors.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Methyldopa; Norepinephrine; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Vagus Nerve; Vascular Resistance | 1973 |
Combination antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamine; Antidepressive Agents; Antihypertensive Agents; Benzothiadiazines; Clonidine; Debrisoquin; Diuretics; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Phenylbutazone; Phytotherapy; Plants, Medicinal; Potassium Chloride; Rauwolfia; Reserpine; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympathomimetics; Triamterene | 1971 |
[Current antihypertensive drugs: mechanism of action].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Catecholamines; Central Nervous System; Clonidine; Diazoxide; Diuretics; Drug Synergism; Guanethidine; Guanidines; Humans; Hydralazine; Methyldopa; Propranolol; Reserpine; Spironolactone | 1973 |
Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies.
Topics: Antihypertensive Agents; Bethanechol Compounds; Clonidine; Diazoxide; Diuretics; Emergencies; Ferricyanides; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Muscle, Smooth; Pargyline; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Vasodilator Agents | 1974 |
The mechanisms of action of some antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Brain; Bretylium Compounds; Clonidine; Debrisoquin; Diuretics; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Methyldopa; Neurons; Normetanephrine; Propranolol; Receptors, Adrenergic; Synaptic Transmission | 1973 |
On the function of central catecholamine neurons--their role in cardiovascular and arousal mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Bradycardia; Brain; Cardiovascular Physiological Phenomena; Catecholamines; Cats; Cerebral Cortex; Clonidine; Dihydroxyphenylalanine; Dopamine; Electric Stimulation; Hypotension; Methyldopa; Neurons; Norepinephrine; Receptors, Cholinergic; Stimulation, Chemical | 1972 |
[Drug therapy of arterial hypertension].
Topics: Antihypertensive Agents; Arteries; Cardiac Output; Clonidine; Diuretics; Drug Combinations; Guanethidine; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Methyldopa; Phytotherapy; Plants, Medicinal; Potassium; Rauwolfia; Vascular Resistance | 1972 |
[Pharmacology of antihypertensive agents].
Topics: Antihypertensive Agents; Clonidine; Diuretics; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Methyldopa; Reserpine | 1974 |
[Side effects of antihypertensive agents].
Topics: Antihypertensive Agents; Autonomic Agents; Benzothiadiazines; Benzyl Compounds; Carbamates; Chlorthalidone; Clonidine; Guanethidine; Guanidines; Humans; Hydralazine; Methyldopa; Plants, Medicinal; Plants, Toxic; Rauwolfia; Veratrum | 1971 |
Centrally acting antihypertensive agents: a brief overview.
Topics: Animals; Antihypertensive Agents; Central Nervous System; Clonidine; Guanabenz; Humans; Hypertension; Methyldopa; Reserpine; Sympathetic Nervous System | 1984 |
Treatment of renal hypertension.
Topics: Adrenergic beta-Antagonists; Chronic Disease; Clonidine; Diuretics; Drug Therapy, Combination; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Diseases; Methyldopa; Pyelonephritis; Recurrence; Renal Artery Obstruction; Vasodilator Agents | 1980 |
Pharmacology of centrally acting hypotensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methyldopa; Phenylacetates; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Yohimbine | 1980 |
The management of hypertension in pregnancy: A review.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagulants; Blood Pressure Determination; Clonidine; Delivery, Obstetric; Diazoxide; Diuretics; Female; Fetus; Hospitalization; Humans; Hypertension; Infant, Newborn; Magnesium Sulfate; Methyldopa; Obstetric Labor Complications; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Reserpine; South Africa; Terminology as Topic; Time Factors; Urate Oxidase | 1980 |
[Current treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Phthalazines; Reserpine | 1980 |
[Therapy of essential arterial hypertension. V].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Drug Evaluation; Drug Therapy, Combination; Guanethidine; Humans; Hypertension; Methyldopa; Reserpine | 1980 |
[Bases of pharmacological therapy of essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Minoxidil; Monoamine Oxidase Inhibitors; Prazosin; Secologanin Tryptamine Alkaloids | 1980 |
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome.
Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Clonidine; Guanabenz; Heart Failure; Humans; Hypertension; Methyldopa; Myocardial Infarction; Pressoreceptors; Prospective Studies; Substance Withdrawal Syndrome; Syndrome; Time Factors | 1981 |
Antihypertensive agents 1969-1980.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Ergolines; Fusaric Acid; Guanidines; Humans; Hydralazine; Indoramin; Methyldopa; Minoxidil; Nifedipine; Piperazines; Prazosin; Prostaglandins | 1981 |
Psychiatric side effects of antihypertensive drugs other than reserpine.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin; Depression; Dreams; Drug Interactions; Female; Ganglionic Blockers; Guanethidine; Hallucinations; Humans; Hydralazine; Hypotension; Male; Mental Disorders; Mental Processes; Methyldopa; Propranolol; Psychotropic Drugs; Sleep; Veratrum Alkaloids | 1982 |
Review of therapeutic modalities acting directly via central pathways.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Catecholamines; Central Nervous System; Clonidine; Hemodynamics; Humans; Hypertension; Methyldopa; Neurotransmitter Agents; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
[Side effects of hypotensive agents].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Bradycardia; Clonidine; Dehydration; Depressive Disorder; Diuretics; Drug Hypersensitivity; Drug Tolerance; Erectile Dysfunction; Heart Block; Humans; Hypertension; Hypokalemia; Hypotension, Orthostatic; Male; Methyldopa; Pulmonary Edema; Sodium Chloride Symporter Inhibitors; Vasodilator Agents | 1982 |
Antihypertensive drug withdrawal syndrome.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Clonidine; Humans; Methyldopa; Risk; Substance Withdrawal Syndrome | 1982 |
Clinical considerations for the hypertensive patient in podiatric practice.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; Middle Aged; Monoamine Oxidase Inhibitors; Podiatry; Sodium Chloride Symporter Inhibitors | 1983 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
Drug-induced sexual dysfunction and infertility.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzothiadiazines; Child; Cimetidine; Clonidine; Cytotoxins; Diuretics; Ejaculation; Erectile Dysfunction; Ethanol; Female; Humans; Infertility; Infertility, Female; Infertility, Male; Ketoconazole; Libido; Male; Methyldopa; Middle Aged; Narcotics; Orgasm; Parasympatholytics; Penis; Phenothiazines; Propranolol; Sexual Dysfunction, Physiological; Sodium Chloride Symporter Inhibitors; Sulfasalazine | 1984 |
Central and peripheral blockade of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics | 1984 |
Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Calcium Channel Blockers; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; Ketanserin; Methyldopa; Muscle, Smooth, Vascular; Phenylacetates; Piperazines; Piperidines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Vascular Resistance | 1984 |
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihypertensive Agents; Asthma; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Ethanolamines; Female; Heart Failure; Humans; Hydralazine; Hypertension; Hypertension, Renal; Infusions, Parenteral; Kidney Failure, Chronic; Labetalol; Methyldopa; Parasympathetic Nervous System; Pheochromocytoma; Pregnancy; Pregnancy Complications, Cardiovascular; Substance Withdrawal Syndrome; Tetanus | 1984 |
Profiling the hypertensive patient in sports.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Diuretics; Exercise Test; Exercise Therapy; Female; Humans; Hypertension; Male; Methyldopa; Physical Examination; Physical Exertion; Physical Fitness; Renin-Angiotensin System; Reserpine; Sports; Vasodilator Agents | 1984 |
The involvement of central alpha adrenoceptors in the antihypertensive actions of methyldopa and clonidine in the rat.
Topics: Animals; Blood Pressure; Brain; Clonidine; Heart Rate; Humans; Methyldopa; Rats; Receptors, Adrenergic, alpha; Sleep, REM; Substance Withdrawal Syndrome | 1984 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.
Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1984 |
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Infant Mortality; Methyldopa; Nitroprusside; Prazosin; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol; Secologanin Tryptamine Alkaloids; Sodium; Sodium Chloride Symporter Inhibitors | 1980 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Metoprolol; Minoxidil; Nitroprusside; Patient Compliance; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors | 1980 |
Hypertensive emergencies: practical approach to treatment.
Topics: Administration, Oral; Antihypertensive Agents; Child; Clonidine; Diazoxide; Emergencies; Female; Humans; Hydralazine; Hypertension; Injections, Intravenous; Male; Methyldopa; Middle Aged; Nitroprusside; Phenoxybenzamine; Phentolamine; Prostaglandins A; Reserpine; Trimethaphan | 1980 |
Clonidine hydrochloride.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Drug Therapy, Combination; Hemodynamics; Humans; Kinetics; Methyldopa; Prazosin; Propranolol; Renin-Angiotensin System; Vasodilator Agents | 1982 |
Management of systemic hypertension in children.
Topics: Adolescent; Antihypertensive Agents; Child; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Nitroprusside; Prazosin; Propranolol | 1982 |
Poisoning with anti-hypertensive drugs: methyldopa and clonidine.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Central Nervous System Diseases; Clonidine; Drug Overdose; Humans; Methyldopa | 1995 |
Aspects of tolerability of centrally acting antihypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Humans; Imidazoles; Methyldopa; Reserpine; Substance Withdrawal Syndrome | 1996 |
[Centrally acting sympathetic inhibitors for therapy of patients with hypertension].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Fibers; Antihypertensive Agents; Clonidine; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Sympatholytics | 1997 |
[Dementia induced by cardiokinetic and anti-hypertensive drugs].
Topics: Antihypertensive Agents; Cardiotonic Agents; Clonidine; Dementia; Digitoxin; Digoxin; Half-Life; Humans; Methyldopa; Propranolol; Reserpine | 2004 |
[Centrally-acting antihypertensive drugs].
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoline Receptors; Kidney; Methyldopa; Norepinephrine; Pressoreceptors; Receptors, Drug; Renal Circulation; Sodium; Sympathetic Nervous System; Sympatholytics; Vascular Resistance | 2004 |
Centrally acting antihypertensive agents: an update.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Oxazoles; Rilmenidine | 2007 |
Older blood pressure medications-do they still have a place?
Topics: Antihypertensive Agents; Chlorthalidone; Clonidine; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Reserpine; Spironolactone; Vasodilator Agents | 2011 |
Postural Orthostatic Tachycardia Syndrome: Mechanisms and New Therapies.
Topics: Adrenergic beta-Antagonists; Cardiovascular Agents; Clonidine; Combined Modality Therapy; Female; Humans; Ivabradine; Male; Methyldopa; Postural Orthostatic Tachycardia Syndrome; Quality of Life; Risk Assessment; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2020 |
23 trial(s) available for clonidine and methyldopa
| Article | Year |
|---|---|
Changing concepts in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Animals; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diazoxide; Diet, Sodium-Restricted; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Methyldopa; Piperazines; Quinazolines; Reserpine; Vasodilator Agents | 1975 |
Antihypertensive effect of prazosin in combination with methyldopa, clonidine, or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Combinations; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Prazosin; Propranolol; Quinazolines | 1979 |
[Study of the hypotensive effect of the combination of a new vasodilator agent (DL 150-IT) with clonidine in the presence of alphamethyldopa].
Topics: Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Vasodilator Agents | 1976 |
Anti-hypertensive adrenergic-blocking agents: effects on sodium balance, the renin-angiotensin system and haemodynamics.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Clonidine; Female; Guanethidine; Humans; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Renin; Reserpine | 1975 |
Use of prazosin in management of hypertension in patients with chronic renal failure and in renal transplant recipients.
Topics: Adult; Aged; Antihypertensive Agents; Chlorothiazide; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Therapy, Combination; Edetic Acid; Female; Furosemide; Humans; Hypertension, Renal; Hypotension, Orthostatic; Kidney Failure, Chronic; Kidney Transplantation; Male; Methyldopa; Middle Aged; Piperazines; Propranolol; Quinazolines | 1975 |
Spironolactone and altizide in systemic hypertension: ambulatory multicenter study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Benzothiadiazines; Clonidine; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Sodium Chloride Symporter Inhibitors; Spironolactone; Sulfonamides | 1990 |
Cerebrospinal fluid norepinephrine levels in essential hypertension: effects of drug treatment and withdrawal.
Topics: Adult; Clonidine; Dopamine; Double-Blind Method; Epinephrine; Humans; Hypertension; Methyldopa; Middle Aged; Norepinephrine; Propranolol; Random Allocation | 1987 |
[Cicletanine administered with other antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nifedipine; Pyridines | 1989 |
Alpha-adrenergic mechanisms in the pathophysiology of left ventricular heart failure--an analysis of their role in systolic and diastolic dysfunction.
Topics: Adrenergic alpha-Antagonists; Autonomic Nervous System; Central Nervous System; Clinical Trials as Topic; Clonidine; Diastole; Guanabenz; Heart Failure; Heart Ventricles; Humans; Methyldopa; Myocardial Contraction; Receptors, Adrenergic, alpha; Stroke Volume; Systole | 1986 |
Clonidine hydrochloride--a safe and effective antihypertensive agent in pregnancy.
Topics: Adult; Apgar Score; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Infant, Newborn; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Random Allocation | 1985 |
The plasma noradrenaline and growth hormone response to alpha-methyldopa and clonidine in hypertensive subjects.
Topics: Adult; Aged; Blood Pressure; Clonidine; Double-Blind Method; Growth Hormone; Humans; Hypertension; Hypnotics and Sedatives; Methyldopa; Middle Aged; Norepinephrine; Random Allocation; Time Factors | 1985 |
Shortcomings of office blood pressures in assessing antihypertensive therapy.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; Timolol | 1985 |
Comparison of clonidine and methyldopa in hypertensive patients receiving a diuretic. A double-blind crossover study.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; Chemistry; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Hypertension; Imidazoles; Male; Methyldopa; Middle Aged; Posture; Time Factors | 1972 |
Clonidine versus methyldopa. A double blind cross-over study comparing side effects of clonidine and methyldopa administered together with chlorthalidone at a dosage producing the same blood pressure lowering effect.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Constipation; Depression; Headache; Humans; Hypertension; Hypotension, Orthostatic; Imidazoles; Male; Methyldopa | 1972 |
Haemodynamic changes in long-term therapy of essential hypertension: a comparative study of diuretics, alpha-methyldopa and clonidine.
Topics: Adult; Cardiac Output; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Polythiazide; Vascular Resistance | 1973 |
[Comparative study of blood pressure, physical complaints and actual emotional condition under clonidine and alpha-methyldopa therapy].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Emotions; Female; Humans; Hypertension; Male; Methyldopa | 1973 |
The Australian National Blood Pressure Study.
Topics: Adult; Aged; Antihypertensive Agents; Australia; Chlorothiazide; Clinical Trials as Topic; Clonidine; Ethics, Medical; Female; Humans; Hydralazine; Hypertension; Male; Mass Screening; Methyldopa; Middle Aged; Pindolol; Placebos; Propranolol | 1974 |
The use of frusemide and propranool in the treatment of the hypertension of chronic renal disease.
Topics: Administration, Oral; Blood Pressure; Clinical Trials as Topic; Clonidine; Creatinine; Furosemide; Homeostasis; Humans; Hypertension, Renal; Methyldopa; Natriuresis; Propranolol; Renin; Sodium | 1974 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depressive Disorder; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Mental Disorders; Methyldopa; Metoprolol; Migraine Disorders; Propranolol; Reserpine; Schizophrenia; Substance Withdrawal Syndrome | 1984 |
[Clonidine-cyclothiazide combination in the therapy of arterial hypertension. Controlled clinical study after oral administration].
Topics: Administration, Oral; Adult; Aged; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Drug Combinations; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged | 1983 |
Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients.
Topics: Aged; Blood Pressure; Clonidine; Dibenzazepines; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Mianserin; Middle Aged; Norepinephrine; Posture; Receptors, Adrenergic, alpha; Renin | 1983 |
[Computerized automatic management of the therapy of arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Clopamide; Computers; Dihydroergotoxine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Mathematics; Methyldopa; Middle Aged; Reserpine | 1981 |
Relationship of psychological factors to failure of antihypertensive drug treatment.
Topics: Adult; Antihypertensive Agents; Bethanidine; Clonidine; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Patient Dropouts; Personality; Time Factors | 1981 |
223 other study(ies) available for clonidine and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
[Drug therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Digitalis Glycosides; Dihydralazine; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Reserpine | 1975 |
Adverse drug reactions during treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Drug Interactions; Humans; Hydralazine; Male; Methyldopa; Middle Aged; Piperazines; Practolol; Quinazolines | 1976 |
Central noradrenergic control of blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dogs; Drug Interactions; Hemodynamics; Hypertension; Methyldopa; Neurons; Norepinephrine; Rabbits; Rats; Receptors, Drug | 1976 |
Diseases of the cardiovascular system Hypertension--II.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Debrisoquin; Diazoxide; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Methyldopa; Phytotherapy; Piperazines; Plants, Medicinal; Quinazolines; Rauwolfia | 1976 |
Management of hypertension.
Topics: Adrenergic alpha-Antagonists; Benzothiadiazines; Clonidine; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypertension; Methyldopa; Patient Care Planning; Patient Compliance; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Trimethaphan; Vascular Resistance; Vasodilator Agents | 1977 |
Blood pressure and heart rate and withdrawal of antihypertensive drugs.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Female; Ganglionic Blockers; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged; Substance Withdrawal Syndrome | 1977 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Minoxidil; Nitroprusside; Prazosin; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympatholytics; Triamterene; Trimethaphan; Vasodilator Agents | 1977 |
[Suppression of the antihypertensive effect of clonidine by the simultaneous intake of a tricyclic antidepressive agent. Practical problem in the treatment of a depressed hypertensive patient].
Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Clomipramine; Clonidine; Depression; Dibenzazepines; Humans; Hypertension; Male; Methyldopa; Monoamine Oxidase Inhibitors | 1977 |
[The orthostatic hypotension in patients treated with antihypertensive drugs (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Antihypertensive Agents; Clonidine; Diuretics; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Methyldopa; Middle Aged | 1977 |
Abnormal sodium transport in leucocytes from patients with essential hypertension and the effect of treatment.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Biological Transport, Active; Blood Pressure; Clonidine; Diuretics; Female; Humans; Hypertension; Hypertension, Malignant; Leukocytes; Male; Methyldopa; Ouabain; Sodium; Sodium Chloride Symporter Inhibitors; Water | 1975 |
Treatment of severe and resistant hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics; Humans; Hydralazine; Hypertension; Injections, Intravenous; Labetalol; Methyldopa; Nitroprusside; Patient Dropouts; Trimethaphan; Vasodilator Agents | 1978 |
[Treatment of arterial hypertension in the aged].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Hypertension, Renovascular; Methyldopa; Prazosin; Prostaglandins, Synthetic; Reserpine | 1978 |
Approach to drug therapy for hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Guanidines; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Patient Care Planning; Patient Compliance; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Vasodilator Agents | 1979 |
Antihypertensive drugs for the aging.
Topics: Aged; Antihypertensive Agents; Clonidine; Ganglionic Blockers; Guanethidine; Humans; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Propranolol; Reserpine; Sympatholytics | 1979 |
Adverse reactions to antihypertensive drug therapy: central nervous system.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Brain; Clonidine; Depression; Humans; Hypnotics and Sedatives; Methyldopa; Reserpine; Sleep Wake Disorders | 1979 |
[The physiological basis of the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensins; Captopril; Central Nervous System; Clonidine; Humans; Hypertension; Methyldopa; Renin; Reserpine; Saralasin; Sodium | 1979 |
Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Barbiturates; Chloralose; Clonidine; Dihydralazine; Guanethidine; Injections, Intra-Arterial; Injections, Intravenous; Male; Methyldopa; Phentolamine; Propranolol; Rats; Reserpine | 1978 |
Review: the significance and management of raised blood pressure in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlormethiazole; Clonidine; Diazepam; Diazoxide; Diuretics; Female; Heparin; Humans; Hydralazine; Hypertension; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 1979 |
[Hypotensive drugs].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Guanidines; Humans; Hypertension; Methyldopa; Minoxidil; Prazosin; Secologanin Tryptamine Alkaloids; Vasodilator Agents | 1979 |
Severe arterial hypertension caused by chronical abuse of a topical mineralocorticoid.
Topics: Adult; Aldosterone; Clonidine; Drug Combinations; Drug Therapy, Combination; Female; Fluprednisolone; Humans; Hypertension; Isomerism; Methyldopa; Naphazoline; Nasal Decongestants; Potassium; Renin; Spironolactone; Substance-Related Disorders; Time Factors; Triamterene | 1975 |
Efficacy of antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Indoramin; Methyldopa; Models, Biological; Posture | 1976 |
[The practitioner and drug-induced, predominantly orthostatic hypotension].
Topics: Adrenergic Agents; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Antipsychotic Agents; Barbiturates; Butyrophenones; Clonidine; Debrisoquin; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypotension, Orthostatic; Levodopa; Meprobamate; Methyldopa; Mineralocorticoids; Monoamine Oxidase Inhibitors; Phenothiazines; Prazosin; Psychotropic Drugs; Reserpine; Vasodilator Agents | 1978 |
Problems in the treatment of hypertension.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Female; Humans; Hypertension; Male; Methyldopa; Patient Compliance; Sodium Chloride Symporter Inhibitors; Time Factors; Vasodilator Agents | 1979 |
[New concepts on central regulation of the blood pressure. Mode of action of clonidine and alpha-methyl DOPA (author's transl)].
Topics: Animals; Blood Pressure; Clonidine; Humans; Hypertension; Methyldopa; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vagus Nerve | 1977 |
Antihypertensive action of clonidine (Catapresan).
Topics: Animals; Blood Pressure; Bradycardia; Brain Stem; Cats; Clonidine; Depression, Chemical; Drug Evaluation; Humans; Hypertension; Methyldopa; Nordefrin; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympathetic Nervous System | 1977 |
Localization of central noradrenergic mechanisms in cardiovascular regulation in rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Heart Rate; Hypothalamus; Injections; Male; Methyldopa; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stereotaxic Techniques | 1975 |
Drug-induced impotence.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Benzodiazepines; Butyrophenones; Clonidine; Erectile Dysfunction; Estrogens; Ethanol; Ganglionic Blockers; Guanethidine; Humans; Male; Methyldopa; Monoamine Oxidase Inhibitors; Narcotics; Parasympatholytics; Phenothiazines; Phenoxybenzamine; Secologanin Tryptamine Alkaloids; Thioxanthenes | 1975 |
[Drug therapy of hypertension in general practice].
Topics: Adrenergic beta-Antagonists; Adult; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Reserpine | 1975 |
Management of hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Bethanidine; Clonidine; Debrisoquin; Decision Making; Diuretics; Female; Guanethidine; Humans; Hypertension; Male; Methyldopa; Pregnancy | 1975 |
Pharmacology update: hypotensive agents. Part II: Antiadrenergic agents.
Topics: Antihypertensive Agents; Clonidine; Guanethidine; Hypertension; Methyldopa; Sympatholytics | 1979 |
Drug therapy today: how to cope with those new antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hydrochlorothiazide; Methyldopa; Propranolol | 1979 |
Drug treatment of mild hypertension: adverse consequences.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Female; Guanethidine; Humans; Hydralazine; Hypertension; Male; Methyldopa; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone | 1978 |
Effects of antihypertensive drugs on blood velocity: implications for prevention of cerebral vascular disease.
Topics: Animals; Antihypertensive Agents; Blood Circulation; Blood Flow Velocity; Cerebrovascular Disorders; Clonidine; Haplorhini; Humans; Hydralazine; Intracranial Aneurysm; Intracranial Arteriosclerosis; Macaca mulatta; Methyldopa; Propranolol | 1977 |
[Effect of hypotensive agents on baroreceptor reflexes in waking animals].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Heart Rate; Methyldopa; Pentobarbital; Pressoreceptors; Reflex; Reserpine | 1979 |
Influence of some hypotensive drugs on the effects of hypothalamic stimulation.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Hypothalamus; Injections, Intraventricular; Lidoflazine; Methyldopa; Norepinephrine; Paraventricular Hypothalamic Nucleus; Propranolol | 1979 |
Influence of clonidine, alpha-methyldopa and hydralazine on noradrenergic and adrenergic neuronal activities in brainstem nuclei of spontaneously hypertensive rats [proceedings].
Topics: Animals; Brain Stem; Clonidine; Dopamine beta-Hydroxylase; Hydralazine; Hypertension; Methyldopa; Phenylethanolamine N-Methyltransferase; Rats; Receptors, Adrenergic | 1979 |
Effects of antihypertensive drugs on dialysis-resistant hypertension, plasma renin and dopamine betahydroxylase activities, metabolic risk factors and calcium phosphate homeostasis: comparison of metoprolol, alphamethyldopa and clonidine in a cross-over t
Topics: Clonidine; Dopamine beta-Hydroxylase; Humans; Hypertension, Renal; Kidney Failure, Chronic; Methyldopa; Metoprolol; Propanolamines; Renal Dialysis; Renin; Risk | 1979 |
[Abolition of the prostaglandin synthesis inhibiting effect of indomethacin by antihypertensives].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Dihydralazine; Indomethacin; Kidney; Methyldopa; Prostaglandins; Rabbits; Reserpine | 1979 |
[Variations in the catecholamine content of the rat brain and heart after administration of alpha-methyldopa, clonidine and diazoxide].
Topics: Animals; Antihypertensive Agents; Brain; Brain Chemistry; Catecholamines; Clonidine; Diazoxide; Heart; Methyldopa; Myocardium; Rats | 1977 |
[Long-term therapy of arterial hypertension. Preliminary report].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Reserpine | 1977 |
3-Methoxy-4-hydroxyphenylglycol in cerebrospinal fluid and vanillylmandelic acid in urine of humans with hypertension.
Topics: Blood Pressure; Clonidine; Female; Glycols; Humans; Hypertension; Male; Methoxyhydroxyphenylglycol; Methyldopa; Vanilmandelic Acid | 1978 |
The effects of antihypertensive medication on the control of the cardiovascular system during halothane anaesthesia in rats.
Topics: Anesthesia, Inhalation; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation, Preclinical; Halothane; Heart Rate; Hydralazine; Hypertension; Male; Methyldopa; Propranolol; Rats; Renin | 1978 |
Adverse effects of sympatholytic agents in patients with hypertension and sinus node dysfunction.
Topics: Aged; Arrhythmia, Sinus; Bradycardia; Clonidine; Electrocardiography; Female; Guanethidine; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Sympatholytics | 1978 |
The hypertensive psychiatric patient: pharmacologic problems.
Topics: Antihypertensive Agents; Clonidine; Depression; Diuretics; Drug Interactions; Guanethidine; Humans; Hydralazine; Hypertension; Lithium; Mental Disorders; Methyldopa; Propranolol; Psychotropic Drugs; Reserpine | 1978 |
Effects of antihypertensive medication on the cardiovascular response to ketamine in rats.
Topics: Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Clonidine; Heart Rate; Hemodynamics; Hydralazine; Infusions, Parenteral; Injections, Intraperitoneal; Ketamine; Male; Methyldopa; Propranolol; Rats; Vasomotor System | 1978 |
The combined effects of antihypertensive drugs and anaesthetics (halothane and ketamine) on the isolated heart.
Topics: Animals; Antihypertensive Agents; Clonidine; Coronary Circulation; Dose-Response Relationship, Drug; Halothane; Heart; Heart Rate; Hemodynamics; Hydralazine; Ketamine; Male; Methyldopa; Myocardial Contraction; Perfusion; Propranolol; Rabbits | 1978 |
Workup and treatment of the average hypertensive patient.
Topics: Benzothiadiazines; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Prazosin; Propranolol; Radiography; Renin; Reserpine; Sodium Chloride Symporter Inhibitors | 1978 |
Changes of prostaglandin synthesis in aorta, brain and kidney medulla of normal rats treated with antihypertensive drugs.
Topics: Animals; Aorta; Blood Pressure; Brain; Clonidine; Dihydralazine; Hydralazine; Kidney Medulla; Methyldopa; Prostaglandins; Rats; Reserpine | 1978 |
Drugs for hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Depression; Diuretics; Drug Combinations; Drug Therapy, Combination; Furosemide; Guanethidine; Humans; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Potassium; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Vasodilator Agents; Water-Electrolyte Imbalance | 1977 |
Antihypertensive agents in renal disease.
Topics: Antihypertensive Agents; Body Water; Clonidine; Diazoxide; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hypertension, Renal; Kidney Failure, Chronic; Methyldopa; Renal Dialysis; Renin; Reserpine; Saralasin; Teprotide; Vasodilator Agents | 1977 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine; Guanethidine; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Methyldopa; Nitroprusside; Pheochromocytoma; Reserpine; Verapamil | 1977 |
Treatment of chronic essential hypertension.
Topics: Chlorothiazide; Clonidine; Diabetes Mellitus; Diet, Sodium-Restricted; Gout; Guanethidine; Humans; Hydralazine; Hypertension; Hypnotics and Sedatives; Medical History Taking; Methyldopa; Patient Compliance; Physical Examination; Phytotherapy; Plants, Medicinal; Potassium; Prazosin; Prognosis; Propranolol; Rauwolfia; Sympathectomy; Tranquilizing Agents | 1977 |
A survey of drug interaction.
Topics: Antacids; Clonidine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Enzyme Inhibitors; Gastrointestinal Motility; Humans; Intestinal Absorption; Methyldopa; Parasympatholytics; Protein Binding; Receptors, Drug | 1977 |
Effect of certain antiadrenergic agents on systolic time intervals in essential hypertension.
Topics: Adult; Clonidine; Electrocardiography; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Sympatholytics; Time Factors | 1977 |
[Pharmacotherapy of arterial hypertension].
Topics: Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hypertension; Methyldopa; Minoxidil; Nitroprusside; Reserpine; Sympatholytics; Vasodilator Agents | 1977 |
Clonidine (Catapres) and other drugs causing sexual dysfunction.
Topics: Advertising; Antihypertensive Agents; Clonidine; Erectile Dysfunction; Female; Guanethidine; Humans; Male; Methyldopa; Psychotropic Drugs; Sexual Dysfunction, Physiological | 1977 |
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation | 1977 |
[Therapy of hypertension with dimapres. Studies on the effect of the anti-hypertensive drug dimapres in newly adjusted and pretreated hypertensive patients].
Topics: Adult; Benzothiadiazines; Clonidine; Diuretics; Drug Combinations; Drug Evaluation; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Physical Exertion; Reserpine; Sodium Chloride Symporter Inhibitors | 1977 |
Diseases of the cardiovascular system. Drugs affecting the cardiovascular system: pharmacological basis of treatment.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Vessels; Cardiac Glycosides; Clonidine; Diazoxide; Humans; Methyldopa; Muscle, Smooth; Myocardial Contraction; Propranolol; Vasodilator Agents | 1976 |
[Methyldopa, clonidine and guanethidine in the treatment of hypertension].
Topics: Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Sympathetic Nervous System | 1976 |
The influence of antihypertensive drugs on the synthesis and metabolism of prostaglandins.
Topics: Animals; Antihypertensive Agents; Brain; Clonidine; Kidney; Methyldopa; Myocardium; Prostaglandins; Rabbits; Reserpine | 1976 |
[Therapeutic combinations, side effects and interactions of antihypertensive drugs].
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Dihydralazine; Diuretics; Drug Interactions; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Propranolol; Reserpine; Spironolactone | 1976 |
[Treatment of hypertensive crises].
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Reserpine; Trimethaphan | 1976 |
[Better therapeutic response and decrease of the collateral negative effects of 2 hypotensive drugs (alpha-methyldopa and clonidine) obtained by means of their association].
Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged | 1976 |
[Changes in kidney function during hypotensive treatment].
Topics: Adult; Aged; Clonidine; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Uremia | 1976 |
Centrally acting alpha-adrenoceptor agonists in hypertension: mechanisms and their role in therapy.
Topics: Animals; Brain; Clonidine; Humans; Hypertension; Male; Methyldopa; Neurons; Substance Withdrawal Syndrome | 1976 |
Reduction of the hypotensive effect of clonidine and alpha-methyldopa by various psychotropic drugs.
Topics: Animals; Blood Pressure; Cats; Clonidine; Depression, Chemical; Iprindole; Methyldopa; Psychotropic Drugs | 1976 |
Letter: Dementia associated with clonidine therapy.
Topics: Aged; Clonidine; Dementia; Humans; Hypertension; Male; Methyldopa | 1975 |
Interaction between centrally acting hypotensive drugs and tricyclic antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cats; Clonidine; Cocaine; Desipramine; Dioxanes; Drug Interactions; Ephedrine; Female; Male; Methyldopa; Piperidines; Reserpine | 1975 |
[Effect of antihypertensive agents on the in vitro biosynthesis of prostaglandin E and F2 alpha in the rabbit kidney medulla].
Topics: Animals; Antihypertensive Agents; Clonidine; Dihydralazine; In Vitro Techniques; Indomethacin; Kidney; Kidney Medulla; Methyldopa; Norepinephrine; Prostaglandins E; Prostaglandins F; Rabbits; Reserpine; Stimulation, Chemical | 1975 |
Evaluation of clonidine hydrochloride (Catapres). A new antihypertensive agent.
Topics: Administration, Oral; Blood Pressure; Cardiac Output; Clonidine; Diuretics; Drug Evaluation; Drug Synergism; Heart Rate; Humans; Hypertension; Injections, Intravenous; Methyldopa; Posture; Substance Withdrawal Syndrome; Vascular Resistance | 1975 |
The hypertensive patient. An algorithm for treatment.
Topics: Administration, Oral; Blood Pressure; Blood Urea Nitrogen; Clonidine; Creatinine; Diazoxide; Diuretics; Hospitalization; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Papilledema; Patient Compliance; Propranolol; Reserpine; Retinal Hemorrhage; Sodium | 1975 |
[Acute prostaglandin E changes in the kidney medulla after intravenous application of blood pressure active drugs in rabbits].
Topics: Animals; Blood Pressure; Clonidine; Dihydralazine; Female; Heart Rate; Indomethacin; Kidney; Kidney Medulla; Male; Methyldopa; Norepinephrine; Prostaglandins E; Rabbits; Reserpine | 1975 |
Applied pharmacology of anti-hypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Trimethaphan | 1976 |
[Tolerance and withdrawal syndrome].
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Antihypertensive Agents; Clonidine; Cyclic AMP; Drug Tolerance; Endorphins; Humans; Methyldopa; Neurotransmitter Agents; Substance Withdrawal Syndrome | 1992 |
Cardiovascular functions of central noradrenergic neurons in rabbits.
Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Heart; Heart Rate; Hydroxydopamines; Methyldopa; Neural Pathways; Neurons; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Rabbits; Sympathetic Nervous System; Vagus Nerve | 1991 |
Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Biperiden; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methyldopa; Mice; Mice, Neurologic Mutants; Motor Activity; N-Methylaspartate; Parasympatholytics; Parkinson Disease; Piperazines | 1991 |
Dual action of clonidine on ethanol-induced gastric lesions: is the imidazoline-preferring receptor involved?
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Ethanol; Guanabenz; Imidazoline Receptors; Male; Methyldopa; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Stomach; Yohimbine | 1991 |
Differences in the central hypotensive actions of alpha-methyldopa and clonidine in the spontaneously hypertensive rat: contribution of neurons arising from the B3 and the C1 areas of the rostral ventrolateral medulla.
Topics: 5,7-Dihydroxytryptamine; Animals; Blood Pressure; Clonidine; Male; Medulla Oblongata; Methyldopa; Microinjections; Neurons; Phentolamine; Rats; Rats, Inbred SHR | 1990 |
First-choice antihypertensive drug use in the Glasgow Blood Pressure Clinic.
Topics: Adrenergic beta-Antagonists; Ambulatory Care Facilities; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Costs and Cost Analysis; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin; Scotland | 1990 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Infusions, Intravenous; Male; Methyldopa; Middle Aged; Nifedipine; Ventricular Function, Left; Verapamil | 1991 |
CNS alpha 2-adrenoceptor induced mydriasis in conscious rats.
Topics: Anesthesia; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Central Nervous System; Clonidine; Light; Male; Methyldopa; Premedication; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Vitamin B6 and hypertension.
Topics: Animals; Blood Pressure; Clonidine; Epinephrine; Hypertension; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Thyroid Gland; Vitamin B 6 Deficiency | 1990 |
Influence of clonidine, methyldopa and propranolol on acute toxicity of fenitrothion in mice.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Fenitrothion; Male; Methyldopa; Mice; Propranolol | 1990 |
Effects of alpha-2 agonists on renal function in hypertensive humans.
Topics: Adrenergic alpha-Agonists; Clonidine; Diuresis; Glomerular Filtration Rate; Guanabenz; Humans; Hypertension; Kidney; Methyldopa; Natriuresis | 1985 |
Alpha 2-adrenoceptor agonists in the treatment of hypertension.
Topics: Adrenergic alpha-Agonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Lipids; Methyldopa | 1985 |
Progress in the treatment of essential hypertension.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Methyldopa; Vasodilator Agents | 1985 |
Importance of spinal noradrenergic pathways in cardiovascular reflexes and central actions of clonidine and alpha-methyldopa in the rabbit.
Topics: Animals; Cardiovascular System; Clonidine; Female; Hydroxydopamines; Male; Methyldopa; Norepinephrine; Oxidopamine; Rabbits; Reflex; Spinal Cord | 1989 |
Centrally mediated increased sympathetic activity is not important in the genesis of ACTH-induced hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Clonidine; Female; Heart Rate; Hypertension; Injections, Intravenous; Methyldopa; Sheep; Sympathetic Nervous System; Vascular Resistance | 1989 |
Centrally acting alpha-2 agonists, peripherally acting adrenergic-blocking drugs, and direct vasodilators in the treatment of mild and moderate essential hypertension.
Topics: Adult; Aged; Black People; Clinical Protocols; Clonidine; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin | 1989 |
Therapy of venous hypertension in calves with total artificial heart (TAH).
Topics: Animals; Antihypertensive Agents; Captopril; Cardiac Pacing, Artificial; Cattle; Central Venous Pressure; Clonidine; Heart, Artificial; Hypertension; Liver Function Tests; Methyldopa; Nifedipine; Postoperative Complications; Prazosin | 1989 |
[Therapy of venous hypertension in animals with an artificial heart and long-term survival].
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Clonidine; Diltiazem; Heart, Artificial; Methyldopa; Nifedipine; Prazosin; Venous Pressure | 1989 |
[Chrono-pharmacodynamics of hypotensive preparations].
Topics: Antihypertensive Agents; Circadian Rhythm; Clonidine; Hemodynamics; Humans; Methyldopa; Propranolol; Time Factors | 1989 |
Pharmacotherapy of "idiopathic" excessive blushing and hyperhidrosis.
Topics: Adrenergic beta-Antagonists; Anti-Infective Agents, Local; Astringents; Blushing; Clonidine; Drug Therapy, Combination; Humans; Hyperhidrosis; Hypnotics and Sedatives; Methyldopa; Parasympatholytics; Sweating | 1985 |
[What is safe in the therapy of hypertensive heart disease?].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clonidine; Coronary Disease; Digitalis Glycosides; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Methyldopa; Pregnancy; Rats; Vasodilator Agents | 1985 |
[Central nervous system side effects of antihypertensive drugs].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Central Nervous System Diseases; Clonidine; Dihydralazine; Diuretics; Humans; Methyldopa; Reserpine | 1986 |
Cardiovascular role of A1 catecholaminergic neurons in the rabbit. Effect of chronic lesions on responses to methyldopa, clonidine and 6-OHDA induced transmitter release.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; Clonidine; Electric Stimulation; Female; Hydroxydopamines; Male; Medulla Oblongata; Methyldopa; Neurons; Neurotransmitter Agents; Oxidopamine; Rabbits; Rest | 1987 |
Sites of actions of alpha 2 agonists in the brain and periphery.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Blood Pressure; Brain; Carbidopa; Clonidine; Decarboxylation; Methyldopa; Neurotransmitter Agents; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoconstriction | 1988 |
Effects of clonidine, alpha-methyldopa and hydralazine on met-enkephalinergic neurons in cerebral nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Enkephalin, Methionine; Fluorescent Antibody Technique; Heart Rate; Hydralazine; Hypertension; Male; Methyldopa; Neurons; Rats; Rats, Inbred SHR; Receptors, Opioid | 1985 |
Role of drugs modifying sympathetic nervous system activity in the treatment of hypertension.
Topics: Binding Sites; Blood Circulation; Brain; Clonidine; Efferent Pathways; Ganglia, Sympathetic; Humans; Hypertension; Methyldopa; Nerve Endings; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Sympatholytics | 1985 |
The importance of fetal/neonatal REM sleep.
Topics: Animals; Animals, Newborn; Behavior, Animal; Biogenic Amines; Clomipramine; Clonidine; Electroencephalography; Eye Movements; Fetus; Methyldopa; Rats; Sleep, REM; Wakefulness | 1986 |
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mortality; Infant, Newborn; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Uric Acid | 1985 |
[Effect of antihypertensive therapy with clonidine and alphamethyldopa on the indirect oxygen consumption index of the myocardium at rest and during exertion].
Topics: Adult; Clonidine; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardium; Oxygen Consumption; Physical Exertion; Rest | 1985 |
[New antihypertensive drugs].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Clopamide; Debrisoquin; Drug Synergism; Female; Guanidines; Humans; Hypertension; Male; Methyldopa; Middle Aged; Vasodilator Agents | 1972 |
Management of severe hypertension.
Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intravascular Coagulation; Ethanolamines; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Pre-Eclampsia; Pregnancy; Propranolol; Renin; Sodium; Spironolactone | 1973 |
[The pharmacology of antihypertensive agents].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Methyldopa; Reserpine | 1973 |
[The treatment of arterial hypertension associated with renal insufficiency].
Topics: Clonidine; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Kidney Failure, Chronic; Methyldopa; Nephrectomy; Phytotherapy; Plants, Medicinal; Rauwolfia; Renal Dialysis | 1973 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Hemodynamics; Humans; Hydralazine; Hypertension; Long-Term Care; Medulla Oblongata; Methyldopa; Monoamine Oxidase Inhibitors; Propranolol; Receptors, Adrenergic; Renin; Reserpine; Synaptic Transmission; Vasomotor System | 1973 |
[Practical medical treatment of essential arterial hypertension].
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Clonidine; Diuretics; Drug Combinations; Guanethidine; Humans; Hypertension; Methyldopa; Vasodilator Agents | 1973 |
[Letter: Diet and drugs in arterial hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Clonidine; Diet, Sodium-Restricted; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine | 1974 |
[Differential therapeutic principles in the drug therapy of high blood pressure].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Cardiac Volume; Clonidine; Diuretics; Drug Combinations; Guanethidine; Humans; Hydralazine; Hypertension; Kidney Failure, Chronic; Methyldopa; Renin; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Time Factors; Triamterene | 1974 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; Ferricyanides; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Hypnotics and Sedatives; Intensive Care Units; Methyldopa; Minoxidil; Nitric Oxide; Pheochromocytoma; Reserpine; Verapamil | 1974 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. II. Antihypertensive agent combinations].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; Heterocyclic Compounds; Humans; Hydrazines; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Reserpine | 1973 |
[General principles of antihypertensive treatment].
Topics: Antihypertensive Agents; Cardiac Output; Clonidine; Follow-Up Studies; Ganglionic Blockers; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Hypotension, Orthostatic; Methyldopa; Secologanin Tryptamine Alkaloids; Sodium; Tachycardia; Vascular Resistance; Vasomotor System; Water-Electrolyte Balance | 1974 |
Treatment of hypertension in the elderly.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Clonidine; Diuretics; Eye Diseases; Ganglionic Blockers; Heart Diseases; Humans; Hypertension; Hypotension; Methyldopa; Myocardial Infarction; Parasympatholytics; Phytotherapy; Plants, Medicinal; Rauwolfia; Vascular Diseases | 1974 |
A standard approach to therapy.
Topics: Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; Hemodynamics; Humans; Hypertension; Methyldopa; Propranolol; Renin; Reserpine; Vasodilator Agents | 1974 |
Adrenolytic and vasodilator therapy.
Topics: Adrenergic beta-Antagonists; Benzyl Compounds; Blood Circulation; Cardiac Output; Clonidine; Diazoxide; Diuretics; Erectile Dysfunction; Ferricyanides; Guanethidine; Guanidines; Humans; Hydralazine; Hypertension; Hypotension, Orthostatic; Lupus Vulgaris; Male; Mental Processes; Methyldopa; Minoxidil; Nitric Oxide; Propranolol; Reserpine; Sodium; Sympatholytics; Vasodilator Agents | 1974 |
Renin suppression.
Topics: Adrenergic beta-Antagonists; Clonidine; Humans; Hypertension; Methyldopa; Renin; Reserpine; Sodium | 1974 |
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clonidine; Dihydroxyphenylalanine; Dioxoles; Disulfides; Fenclonine; Humans; Hydrazines; Hydroxybutyrates; Imidazoles; Iproniazid; Male; Methyldopa; Methyltyrosines; Phenoxybenzamine; Piperazines; Rats; Reserpine; Serotonin; Thiocarbamates; Time Factors | 1974 |
[How to advance antihypertensive therapy].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Humans; Hypertension; Methyldopa; Middle Aged; Mineralocorticoid Receptor Antagonists; Prostaglandins; Renin; Spironolactone; Time Factors | 1974 |
[Antihypertensive agents and anesthesia].
Topics: Adrenergic beta-Antagonists; Anesthetics; Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Methyldopa; Monoamine Oxidase Inhibitors; Plants, Medicinal; Propylamines; Rauwolfia | 1972 |
Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat.
Topics: Animals; Antihypertensive Agents; Cats; Cellophane; Clonidine; Corticosterone; Delayed-Action Preparations; Disease Models, Animal; Guanethidine; Hydralazine; Hypertension; Ligation; Methyldopa; Pempidine | 1974 |
[Possibilities and limitations of hypertensive therapy].
Topics: Clonidine; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Reserpine; Sympatholytics | 1974 |
[Critical exertion pressure in patients with hypertension. Results of direct blood-pressure measurement under everyday and ergometric stress conditions, conclusions for the practice].
Topics: Adult; Blood Pressure; Blood Pressure Determination; Clonidine; Exercise Test; Female; Guanethidine; Humans; Hypertension; Male; Methyldopa; Middle Aged; Physical Exertion; Pulse; Reserpine; Time Factors | 1974 |
[Evaluation of the clinical effectiveness of clonidine used alone and in combination with a diuretic or methylodopa].
Topics: Adult; Benzothiadiazines; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Humans; Hypertension; Methyldopa; Sodium Chloride Symporter Inhibitors | 1974 |
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan | 1972 |
Editorial: Hypertension and depression and their treatment.
Topics: Animals; Antidepressive Agents; Antihypertensive Agents; Clonidine; Depression; Humans; Hypertension; Methyldopa; Propranolol; Reserpine | 1973 |
Effect of L-DOPA and analogues on central dopamine and noradrenaline mechanisms.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Methyldopa; Methyltyrosines; Movement; Nialamide; Norepinephrine; Octopamine; Rats; Receptors, Drug; Reflex; Reserpine; Spinal Cord; Stimulation, Chemical; Tyramine; Tyrosine | 1974 |
[Medical treatment of severe or malignant arterial hypertension].
Topics: Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Hemodynamics; Humans; Hypertension, Malignant; Kidney Failure, Chronic; Methyldopa; Prognosis | 1972 |
[Hemodynamics and anti-hypertensive treatment].
Topics: Antihypertensive Agents; Clonidine; Diuretics; Guanethidine; Hemodynamics; Humans; Hypertension; Methyldopa; Propranolol | 1972 |
[Principles and management of antihypertensive treatment].
Topics: Antihypertensive Agents; Carotid Sinus; Clonidine; Electric Stimulation; Ferricyanides; Guanethidine; Humans; Hypertension; Methods; Methyldopa | 1972 |
[Treatment of arterial hypertension with new drugs. 1. Severe arterial hypertension].
Topics: Antihypertensive Agents; Body Weight; Clonidine; Diuresis; Furosemide; Hemodynamics; Humans; Hypertension; Methyldopa; Sodium; Sodium Chloride; Spironolactone; Urea | 1972 |
Dopamine and noradrenaline receptor stimulation: reversal of reserpine-induced suppression of motor activity.
Topics: Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Female; Methyldopa; Mice; Motor Activity; Norepinephrine; Receptors, Drug; Reserpine; Spinal Cord; Stimulation, Chemical | 1973 |
Clonidine in the treatment of severe hypertension.
Topics: Adult; Anesthesia, General; Cerebrovascular Disorders; Clonidine; Coronary Disease; Depression; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Male; Methyldopa; Middle Aged; Sexual Behavior; Substance Withdrawal Syndrome | 1973 |
[Hypertension of renal origin].
Topics: Clonidine; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydralazine; Hypertension, Renal; Kidney Diseases; Kidney Failure, Chronic; Methyldopa; Nephritis, Interstitial; Renal Artery Obstruction; Renin; Reserpine; Sodium | 1973 |
[Medical treatment of arterial hypertension in adults].
Topics: Adult; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Guanethidine; Humans; Hydrazines; Hypertension; Male; Methyldopa; Reserpine; Spironolactone; Time Factors | 1973 |
Hypertension.
Topics: Antihypertensive Agents; Body Weight; Clonidine; Humans; Hypertension; Methyldopa; Propranolol; Smoking | 1973 |
[Hypertension: 3 H-catecholamine metabolism in the adrenal glands and brain and tissue metabolism of 3 3 H-DOPA during reserpine, alpha-methyl DOPA and ST-155 administration in spontaneously hypertensive rats].
Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Brain; Catecholamines; Clonidine; Dihydroxyphenylalanine; Dopamine; Female; Hypertension; Male; Methyldopa; Norepinephrine; Organ Size; Rats; Reserpine; Tritium | 1973 |
Drugs used in the treatment of hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ethacrynic Acid; Ferricyanides; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Nitric Oxide; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Vasodilator Agents | 1973 |
[The effect of prolonged treatment hypertensive rats with antihypertensive agents with different mechanisms of action on blood pressure and noradrenaline concentration in the myocardium, brain and aorta].
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Brain Chemistry; Clonidine; Disulfiram; Furosemide; Guanethidine; Hypertension; Male; Methyldopa; Myocardium; Norepinephrine; Rats; Reserpine | 1973 |
[Anti-hypertensive action of 3 drugs inhibiting the sympathetic nervous system. Hemodynamic and biological study].
Topics: Adult; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Propranolol; Renin; Sodium | 1974 |
Comparison of clonidine and methyldopa on blood pressure and side effects in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Imidazoles; Methyldopa | 1972 |
[Antihypertensive therapy].
Topics: Adult; Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Rauwolfia; Spironolactone; Sympatholytics | 1972 |
Natriuretic and water diuretic effects of central alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Blood Pressure; Blood Volume; Clonidine; Diuresis; Guanabenz; Homeostasis; Humans; Methyldopa; Natriuresis; Sodium; Water-Electrolyte Balance | 1984 |
Thyrotropin releasing hormone and naloxone attenuate the antihypertensive action of central alpha 2-adrenoceptor stimulation through different mechanisms.
Topics: Animals; Antihypertensive Agents; Biomechanical Phenomena; Clonidine; Male; Methyldopa; Naloxone; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Stimulation, Chemical; Thyrotropin-Releasing Hormone | 1984 |
Effects of naloxone on the cardiovascular responses to clonidine, alpha-methyldopa and 6-hydroxydopamine in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Central Nervous System; Clonidine; Drug Interactions; Endorphins; Hydroxydopamines; Male; Methyldopa; Naloxone; Oxidopamine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Errors in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; Patient Compliance; Prazosin | 1980 |
Adverse drug reactions to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Physician-Patient Relations; Prazosin; Sodium Chloride Symporter Inhibitors | 1980 |
Antihypertensive drugs that alter adrenergic function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catecholamines; Central Nervous System; Clonidine; Guanethidine; Humans; Methyldopa; Metoprolol; Nadolol; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System | 1980 |
What patients with hypertension should know about their medication.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyldopa; Patient Education as Topic; Prazosin; Sympatholytics | 1980 |
Adverse effects of sudden withdrawal of antihypertensive medication.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Therapy, Combination; Humans; Methyldopa; Norepinephrine; Substance Withdrawal Syndrome; Sympathetic Nervous System; Syndrome | 1980 |
Effects of alpha-adrenoceptor-stimulating drugs on baroreceptor reflexes in conscious cats.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Clonidine; Electric Stimulation; Hemodynamics; Humans; Hypothalamus; Male; Methyldopa; Pressoreceptors; Reserpine; Stress, Psychological | 1980 |
[Hypertension treatment in the elderly].
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Clonidine; Diuretics; Drug Therapy, Combination; Electrolytes; Hemodynamics; Humans; Hypertension; Methyldopa | 1981 |
Abrupt discontinuation of antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Drug Therapy, Combination; Humans; Hypertension; Methyldopa; Prospective Studies; Substance Withdrawal Syndrome | 1981 |
Hemodynamic effects of antihypertensive agents.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzothiadiazines; Cardiac Output; Clonidine; Diuretics; Follow-Up Studies; Hemodynamics; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Risk; Sodium Chloride Symporter Inhibitors; Stroke Volume | 1983 |
[Antihypertensive therapy in pregnancy].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 1982 |
[The use of vasodilator agents in the therapy of chronic cardiac insufficiency].
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Captopril; Clonidine; Diuretics; Heart Failure; Humans; Methyldopa; Nitrates; Nitroprusside; Prazosin; Vasodilator Agents | 1982 |
The influence of SK & F 64139, a phenylethanolamine-N-methyltransferase inhibitor, on centrally mediated cardiovascular effects of alpha-methyldopa and clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Clonidine; Heart Rate; Isoquinolines; Male; Methyldopa; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines | 1982 |
Antihypertensives and their impact on renal function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Captopril; Central Nervous System; Clonidine; Glomerular Filtration Rate; Humans; Kidney; Labetalol; Methyldopa; Prazosin; Renal Circulation; Vasodilator Agents | 1983 |
Sexual dysfunction due to antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydralazine; Male; Methyldopa; Prazosin; Propranolol; Reserpine; Sex; Sexual Dysfunction, Physiological; Sodium Chloride Symporter Inhibitors; Spironolactone | 1984 |
alpha-Adrenoceptors.
Topics: Adrenergic alpha-Agonists; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Humans; Hypertension; Imidazoles; Kidney; Methyldopa; Phenethylamines; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Synaptic Transmission | 1984 |
Office management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Captopril; Clonidine; Diuretics; Guanabenz; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors | 1984 |
Use of sympatholytic and vasodilator drugs.
Topics: Adrenergic beta-Antagonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanethidine; Humans; Hypertension; Hypertension, Malignant; Methyldopa; Reserpine; Sympatholytics; Vasodilator Agents | 1984 |
Neuropsychiatric manifestations of antihypertensive medications.
Topics: Adrenergic beta-Antagonists; Affective Symptoms; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors | 1983 |
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methyldopa; Metoprolol; Middle Aged | 1983 |
Tonic immobility and the alpha-adrenergic system in chickens.
Topics: Animals; Chickens; Clonidine; Epinephrine; Isoproterenol; Methoxamine; Methyldopa; Motor Activity; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Antagonism; Female; Methyldopa; Motor Activity; Nordefrin; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1980 |
alpha-Methylepinephrine, a methyldopa metabolite that binds to alpha-receptors in rat brain.
Topics: Animals; Binding, Competitive; Brain; Clonidine; Dioxanes; Epinephrine; Kinetics; Male; Methyldopa; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Pharmacology and characterization of central alpha-adrenoceptors involved in the effect of centrally acting antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Heart Rate; Medulla Oblongata; Methyldopa; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Synapses | 1983 |
beta-endorphin acting on the brainstem is involved in the antihypertensive action of clonidine and alpha-methyldopa in rats.
Topics: Animals; beta-Endorphin; Blood Pressure; Clonidine; Desoxycorticosterone; Endorphins; Heart Rate; Hypertension; Hypertension, Renal; Immune Sera; Male; Methyldopa; Naltrexone; Rats; Rats, Inbred Strains; Rats, Mutant Strains | 1983 |
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension.
Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Vasodilator Agents | 1984 |
Effect of alpha-methyldopa on alpha-noradrenergic receptor binding sites in the mouse brain.
Topics: Animals; Brain; Brocresine; Clonidine; Dioxanes; Ditiocarb; Fusaric Acid; Male; Methyldopa; Methyltyrosines; Mice; Mice, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine | 1984 |
Disparate effects of methyldopa and clonidine on cardiac mass and haemodynamics in rats.
Topics: Animals; Body Weight; Cardiomegaly; Clonidine; Hemodynamics; Hypertension; Methyldopa; Myocardium; Organ Size; Rats; Regional Blood Flow | 1980 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; Clonidine; Heart; Hemodynamics; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains | 1982 |
Influence of alpha-methyldopa treatment on adrenergic receptor binding in rat forebrain.
Topics: Animals; Brain; Clonidine; Dihydroalprenolol; Male; Methyldopa; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Tritium | 1983 |
Effects of acute and short-term treatment with antihypertensive drugs in sinoaortic denervated rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Clonidine; Denervation; Female; Heart Rate; Hypertension; Methyldopa; Rats; Rats, Inbred Strains; Sinoatrial Node; Time Factors | 1983 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clonidine; Drug Combinations; Drug Evaluation; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracranial Arteriosclerosis; Methyldopa; Middle Aged; Reserpine; Time Factors | 1984 |
Clonidine and methyldopa--any role for hypertension now?
Topics: Clonidine; Humans; Hypertension; Methyldopa; Substance Withdrawal Syndrome | 1984 |
Potassium disposition and neuroendocrine effects of propranolol, methyldopa and clonidine during dynamic exercise.
Topics: Aldosterone; Blood Pressure; Clonidine; Double-Blind Method; Heart Rate; Humans; Methyldopa; Norepinephrine; Physical Exertion; Placebos; Potassium; Propranolol; Renin | 1982 |
Progesterone positive feedback on gonadotropin release in estrogen-primed postmenopausal women: central nervous system and pituitary as possible sites of action.
Topics: Aged; Bromocriptine; Clonidine; Ethinyl Estradiol; Feedback; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Menopause; Methyldopa; Middle Aged; Progesterone; Prolactin | 1981 |
Abrupt cessation of treatment with centrally acting antihypertensive agents. A review.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension; Methyldopa; Renin-Angiotensin System; Substance Withdrawal Syndrome; Sympathetic Nervous System; Time Factors | 1983 |
Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dibenzazepines; Double-Blind Method; Drug Interactions; Humans; Hypertension; Hypnotics and Sedatives; Male; Methyldopa; Mianserin; Middle Aged; Salivation | 1983 |
Impairment of environmental effects on brain weight by adrenergic drugs in rats.
Topics: Animals; Clonidine; Male; Methyldopa; Muridae; Neuronal Plasticity; Occipital Lobe; Organ Size; Rats; Sleep Deprivation; Sleep, REM; Social Environment | 1983 |
Clonidine withdrawal complicated by amitriptyline therapy.
Topics: Aged; Amitriptyline; Anxiety; Clonidine; Female; Humans; Hypertension; Intraoperative Care; Methyldopa; Nitroprusside; Postoperative Care; Propranolol; Substance Withdrawal Syndrome; Tachycardia | 1983 |
What to watch for with clonidine and methyldopa.
Topics: Clonidine; Drug Interactions; Humans; Hypertension; Methyldopa | 1982 |
Differential competition by L-alpha-methyldopa metabolites for adrenergic receptors in rat forebrain.
Topics: Animals; Binding, Competitive; Brain; Catecholamines; Clonidine; In Vitro Techniques; Kinetics; Male; Methyldopa; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Stereoisomerism | 1982 |
Hypertension in older patients: what drugs to use and when.
Topics: Aged; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hypertension; Hypotension, Orthostatic; Male; Methyldopa; Middle Aged; Prazosin; Propranolol; Reserpine; Systole | 1982 |
Evidence that alpha-methylepinephrine is an antihypertensive metabolite of alpha-methyldopa.
Topics: Animals; Biotransformation; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Hypertension; Isoquinolines; Male; Methyldopa; Phenylethanolamine N-Methyltransferase; Rats; Tetrahydroisoquinolines | 1982 |
Sexual dysfunction associated with oral antihypertensive medication: a critical survey of the literature.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Erectile Dysfunction; Guanethidine; Humans; Hypertension; Male; Methyldopa; Propranolol; Reserpine; Spironolactone | 1982 |
Cerebral acting maps of hydralazine, clonidine, and alpha-methyldopa in spontaneously hypertensive rats as demonstrated by the 14C-deoxy-D-glucose method.
Topics: Animals; Blood Pressure; Brain; Clonidine; Deoxy Sugars; Deoxyglucose; Hydralazine; Hypertension; Male; Methyldopa; Pressoreceptors; Rats; Rats, Inbred Strains | 1982 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hydralazine; Hypotension; Male; Mecamylamine; Methyldopa; Minoxidil; Phentolamine; Posture; Prazosin; Propranolol; Rats; Reserpine; Sympathetic Nervous System | 1981 |
Effect of chronic administration of clonidine, propranolol and alpha-methyldopa on extensibility and biochemical properties of the veins in renal and spontaneous hypertension.
Topics: Adipose Tissue; Animals; Antihypertensive Agents; Body Water; Clonidine; DNA; Elasticity; Female; Hemodynamics; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Methyldopa; Phenoxybenzamine; Phentolamine; Propranolol; Proteins; Rats; Veins | 1981 |
Effect of antihypertensive therapy on plasma catecholamines in renal failure patients.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Kidney Failure, Chronic; Methyldopa; Middle Aged; Norepinephrine | 1981 |
[Antihypertensive drugs acting at the nervous system level. 2. Central action].
Topics: Antihypertensive Agents; Brain; Clonidine; Humans; Hypnotics and Sedatives; Methyldopa; Veratrum Alkaloids | 1981 |
Antihypertensive effect of BS 100-141, a new central acting antihypertensive agent.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Phenylacetates; Propranolol; Time Factors | 1980 |
[Treatment of malignant arterial hypertension].
Topics: Acute Kidney Injury; Clonidine; Diazoxide; Dihydralazine; Diuretics; Humans; Hypertension, Malignant; Methyldopa; Nitroprusside | 1980 |
Special considerations in treating hypertension in the elderly.
Topics: Aged; Clonidine; Diet, Sodium-Restricted; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Prazosin | 1980 |
Differential effects of alpha-methyldopa, clonidine and hydralazine on norepinephrine and epinephrine synthesizing enzymes in the brainstem nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Brain Stem; Clonidine; Depression, Chemical; Dopamine beta-Hydroxylase; Heart Rate; Hydralazine; Hypertension; Methyldopa; Norepinephrine; Phenylethanolamine N-Methyltransferase; Rats; Spinal Cord | 1980 |
[Alpha-methyldopa and renal function in arterial hypertension].
Topics: Antihypertensive Agents; Clonidine; Dihydralazine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney; Kidney Function Tests; Methyldopa; Propranolol | 1980 |
[Treatment of essential arterial hypertension with a combination of clonidine and alpha-methyldopa].
Topics: Adult; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyperglycemia; Hypertension; Hypokalemia; Male; Methyldopa; Minoxidil; Prazosin; Propranolol; Reserpine; Sodium Chloride Symporter Inhibitors; Uric Acid | 1981 |
Differential role of brain ascending noradrenergic bundles in the circulatory effects of alpha-methyldopa and clonidine.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Brain; Clonidine; Dopamine; Female; Heart Rate; Male; Methyldopa; Neural Pathways; Norepinephrine; Oxidopamine; Prosencephalon; Rabbits | 1993 |
Differential receptors involved in the cardiovascular effects of clonidine and rilmenidine in conscious rabbits.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Dioxanes; Female; Idazoxan; Imidazoline Receptors; Male; Methyldopa; Oxazoles; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine | 1993 |
In vitro study of the effect of clonidine on human umbilical artery motility.
Topics: Clonidine; Humans; In Vitro Techniques; Infant, Newborn; Methyldopa; Umbilical Arteries; Vasoconstriction; Yohimbine | 1994 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats: an historical account and some follow-up.
Topics: Animals; Bibliometrics; Clonidine; Heart; History, 20th Century; Hydralazine; Hypertension; Methyldopa; Publishing; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2000 |
Effect of binders on anti hypertensive drugs.
Topics: Antihypertensive Agents; Chemical Phenomena; Chemistry, Physical; Clonidine; Excipients; Indapamide; Methyldopa; Tablets | 1999 |
The effects of nitric oxide synthase inhibitors on the sedative effect of clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hypnotics and Sedatives; Indazoles; Male; Methyldopa; Midazolam; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Sleep; Thiopental | 2001 |
Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Binding Sites; Binding, Competitive; Brain; Carbidopa; Clonidine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Enzyme Inhibitors; Female; Isoquinolines; Kinetics; Lactation; Levodopa; Male; Mazindol; Median Eminence; Methyldopa; Pituitary Gland; Pituitary Gland, Posterior; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reserpine | 2003 |
Centrally active nonhormonal hot flash therapies.
Topics: Amines; Antidepressive Agents; Antihypertensive Agents; Belladonna Alkaloids; Clonidine; Cyclohexanecarboxylic Acids; Drug Combinations; Ergotamines; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Methyldopa; Methysergide; Phenobarbital | 2005 |
Investigation of the effects of the chronic administration of some antihypertensive drugs on enzymatic and non-enzymatic oxidant/antioxidant parameters in rat ovarian tissue.
Topics: Amlodipine; Animals; Antihypertensive Agents; Antioxidants; Clonidine; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Methyldopa; Ovary; Oxazoles; Oxidants; Ramipril; Rats; Rats, Wistar; Rilmenidine; Superoxide Dismutase | 2011 |
Antihypertensive drugs methyldopa, labetalol, hydralazine, and clonidine improve trophoblast interaction with endothelial cellular networks in vitro.
Topics: Antihypertensive Agents; Cells, Cultured; Clonidine; Coculture Techniques; Culture Media, Conditioned; Cytokines; Endothelium, Vascular; Female; Humans; Hydralazine; In Vitro Techniques; Labetalol; Methyldopa; Trophoblasts | 2014 |
Antihypertensive methyldopa, labetalol, hydralazine, and clonidine reversed tumour necrosis factor-α inhibited endothelial nitric oxide synthase expression in endothelial-trophoblast cellular networks.
Topics: Antihypertensive Agents; Cells, Cultured; Clonidine; Coculture Techniques; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Female; Humans; Hydralazine; Interleukin-1 Receptor-Like 1 Protein; Labetalol; Methyldopa; Nitric Oxide Synthase Type III; Trophoblasts; Tumor Necrosis Factor-alpha; Uterus | 2017 |