clonidine and meperidine

clonidine has been researched along with meperidine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19905 (12.50)18.7374
1990's14 (35.00)18.2507
2000's15 (37.50)29.6817
2010's4 (10.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jiang, Z1
Bortone, F; Ceriani, R; Moruzzi, P; Ruju, P; Salvi, L; Solinas, C; Susini, G1
Clemente, E; Giron, GP; Micaglio, M; Pigato, P; Pizzirani, E; Rizzoli, G; Thiener, A1
Harris, S; Lloyd, P; Messineo, E; Ossipov, MH1
Kaukinen, S; Toivonen, J1
Gusmorino, P; Jimenez, AC; Pinter, I; Snow, B1
Gillman, MA; Lichtigfeld, FJ1
Reddy, SV; Yaksh, TL1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Haggerty, JJ; Slatkoff, S1
Conti, G; de Blasi, RA; Gasparetto, A; La Rosa, I; Orsi, P; Pinto, G; Rosa, G; Sanitá, R1
Fee, JP; Grace, D; Milligan, KR; Morrow, BJ1
Henderson, CJ; Liu, Z; Rane, A; Wolf, CR1
De Michele, P; Letterio, G; Mercadante, S; Pignataro, A; Sapio, M; Villari, P1
Bédard, PJ; Gomez-Mancilla, B1
Bhatti, TH; Khan, RM; Maroof, M1
Berg, K; Grundmann, U; Juckenhöfel, S; Stamminger, U; Wilhelm, W1
Acalovschi, I; Bodolea, C; Manoiu, C1
Büchs, C; Horn, EP; Schulte am Esch, J; Sessler, DI; Standl, T; von Knobelsdorff, G1
Boldt, J; Maleck, WH; Piper, SN; Reich, DG; Schmidt, CC; Suttner, SW1
Fritz, HG; Hartmann, M; Hoff, H; Schwarzkopf, KR1
Johnson, CN1
Eberhart, LH; Kranke, P; Roewer, N; Tramèr, MR1
Hall, DL; Rezvan, E; Tatakis, DN; Walters, JD1
van der Vegt, MH; van Kan, HJ; Vranken, JH1
de Carvalho, HG; Dórea, EM; Módolo, NS; Nascimento, Jdos S; Santos, KP1
Arici, G; Erman, M; Ertugrul, F; Karsli, B; Kayacan, N; Nacitarhan, C; Sadan, G1
Bein, B; Brand, PA; Höcker, J; Ohnesorge, H; Scholz, J; Tonner, PH; Weber, B1
Cook, AM; Humphries, RL; Martin, JE; Weant, KA1
Atef, AM; Awais, WM; Yousef, AA1
Abdallah, S; Gaballah, K1
Al-Dahna, T; Dinges, HC; Eberhart, L; Rücker, G; Schubert, AK; Wiesmann, T; Wulf, H1

Reviews

5 review(s) available for clonidine and meperidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Intravenous regional anesthesia: new approaches to an old technique.
    CRNA : the clinical forum for nurse anesthetists, 2000, Volume: 11, Issue:2

    Topics: Adjuvants, Anesthesia; Analgesics; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Humans; Ketorolac; Meperidine; Nurse Anesthetists; Tourniquets

2000
Pharmacological treatment of postoperative shivering: a quantitative systematic review of randomized controlled trials.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:2

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Clonidine; Humans; Ketanserin; Lidocaine; Meperidine; Postoperative Complications; Randomized Controlled Trials as Topic; Shivering

2002
Pharmacologic options for reducing the shivering response to therapeutic hypothermia.
    Pharmacotherapy, 2010, Volume: 30, Issue:8

    Topics: Body Temperature; Clonidine; Dexmedetomidine; Humans; Hypothermia, Induced; Meperidine; Pharmacists; Shivering

2010
Pharmacologic interventions for the therapy of postanesthetic shivering in adults: a systematic review and network meta-analysis.
    Minerva anestesiologica, 2023, Volume: 89, Issue:10

    Topics: Adult; Clonidine; Doxapram; Humans; Meperidine; Methylphenidate; Nefopam; Network Meta-Analysis; Shivering; Tramadol

2023

Trials

14 trial(s) available for clonidine and meperidine

ArticleYear
[The therapy of postoperative shivering: comparison of drugs].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Anesthesia Recovery Period; Clonidine; Humans; Meperidine; Methylphenidate; Shivering

1991
Clonidine premedication: a useful adjunct in producing deliberate hypotension.
    Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:8

    Topics: Adult; Blood Pressure; Clonidine; Creatinine; Ear, Middle; Electrocardiography; Female; Heart Rate; Hemostasis, Surgical; Humans; Hypotension, Controlled; Isoflurane; Labetalol; Male; Meperidine; Middle Aged; Preanesthetic Medication; Urine

1990
Control of post anaesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Basal Metabolism; Blood Pressure; Body Temperature; Brain; Carbon Dioxide; Cerebrospinal Fluid Pressure; Cerebrovascular Circulation; Clonidine; Elective Surgical Procedures; Electroencephalography; Energy Metabolism; Female; Humans; Hypothermia; Male; Meperidine; Nefopam; Oxygen Consumption; Postoperative Period; Shivering

1995
Co-administration of pethidine and clonidine: a spinal anaesthetic technique for total hip replacement.
    British journal of anaesthesia, 1994, Volume: 73, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Blood Pressure; Bupivacaine; Clonidine; Female; Hip Prosthesis; Humans; Male; Meperidine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

1994
Effect of clonidine on postpartum shivering after epidural analgesia: a randomized, controlled, double-blind study.
    Journal of pain and symptom management, 1994, Volume: 9, Issue:5

    Topics: Adult; Analgesia, Epidural; Clonidine; Double-Blind Method; Female; Humans; Meperidine; Postpartum Period; Shivering

1994
[Comparative study of pethidine and clonidine for prevention of postoperative shivering. A prospective, randomized, placebo-controlled double-blind study].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1997, Volume: 32, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthesia, General; Body Temperature Regulation; Clonidine; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; Male; Meperidine; Microsurgery; Middle Aged; Pain Measurement; Postoperative Complications; Prospective Studies; Shivering; Sympatholytics

1997
Spinal anesthesia with meperidine. Effects of added alpha-adrenergic agonists: epinephrine versus clonidine.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Anesthesia, Spinal; Blood Pressure; Clonidine; Double-Blind Method; Epinephrine; Female; Humans; Injections, Spinal; Male; Meperidine; Middle Aged; Pain, Postoperative

1997
Physostigmine prevents postanesthetic shivering as does meperidine or clonidine.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Adult; Aged; Anesthesia; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Male; Meperidine; Middle Aged; Physostigmine; Shivering

1998
A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:4

    Topics: Adult; Aged; Anesthesia, General; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Meperidine; Middle Aged; Piperazines; Shivering

2000
A comparison between meperidine, clonidine and urapidil in the treatment of postanesthetic shivering.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Blood Pressure; Clonidine; Double-Blind Method; Female; Humans; Male; Meperidine; Oxygen; Piperazines; Shivering

2001
Oral clonidine pre-treatment and diazepam/meperidine sedation.
    Journal of dental research, 2006, Volume: 85, Issue:9

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Intravenous; Blood Pressure; Clonidine; Conscious Sedation; Cross-Over Studies; Diazepam; Electroencephalography; Female; Humans; Likelihood Functions; Male; Meperidine; Middle Aged; Preanesthetic Medication; Respiration; Statistics, Nonparametric; Surveys and Questionnaires

2006
Clonidine in cineangiocardiography: sedative effects on blood pressure and heart rate.
    Arquivos brasileiros de cardiologia, 2006, Volume: 87, Issue:5

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Cineangiography; Clonidine; Coronary Angiography; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Meperidine; Middle Aged; Prospective Studies

2006
Comparison of fentanyl versus meperidine as supplements to epidural clonidine-bupivacaine in patients with lower limb orthopedic surgery under combined spinal epidural anesthesia.
    BMC anesthesiology, 2015, Oct-14, Volume: 15

    Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, Spinal; Bupivacaine; Clonidine; Drug Therapy, Combination; Female; Fentanyl; Humans; Male; Meperidine; Middle Aged; Orthopedic Procedures; Pain, Postoperative

2015
Effects of oral premedication with tramadol, pregabalin or clonidine on shivering after spinal anaesthesia in patients undergoing hysteroscopic procedures.
    Anaesthesiology intensive therapy, 2020, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Spinal; Body Temperature; Clonidine; Conscious Sedation; Double-Blind Method; Female; Humans; Hysteroscopy; Meperidine; Middle Aged; Narcotics; Pregabalin; Premedication; Prospective Studies; Shivering; Tramadol; Treatment Outcome; Young Adult

2020

Other Studies

21 other study(ies) available for clonidine and meperidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Iatrogenic addiction of pethidine: clinical feature and experience of detoxification].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:2

    Topics: Adult; Clonidine; Female; Humans; Iatrogenic Disease; Male; Meperidine; Methadone; Substance-Related Disorders

1992
[Effectiveness and hemodynamic effects of clonidine, meperidine, taurine, ketanserin in the therapy of post-anesthesia shivering in patients undergoing ECC in moderate hypothermia].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Anesthesia Recovery Period; Clonidine; Extracorporeal Circulation; Hemodynamics; Humans; Hypothermia, Induced; Ketanserin; Meperidine; Prospective Studies; Shivering; Taurine

1991
An isobolographic analysis of the antinociceptive effect of systemically and intrathecally administered combinations of clonidine and opiates.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Clonidine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Fentanyl; Hot Temperature; Infrared Rays; Injections, Intravenous; Injections, Spinal; Male; Meperidine; Morphine; Narcotics; Nociceptors; Rats; Rats, Inbred Strains

1990
The use of clonidine for the treatment of meperidine withdrawal in a multidisciplinary pain program setting. A case presentation.
    Bulletin of the Hospital for Joint Diseases Orthopaedic Institute, 1987,Spring, Volume: 47, Issue:1

    Topics: Adult; Clonidine; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Meperidine; Pain; Substance Withdrawal Syndrome

1987
Analgesic nitrous oxide: adjunct to clonidine for opioid withdrawal.
    The American journal of psychiatry, 1985, Volume: 142, Issue:6

    Topics: Adult; Clonidine; Drug Therapy, Combination; Female; Humans; Meperidine; Morphine; Morphine Dependence; Nitrous Oxide; Oxygen; Substance Withdrawal Syndrome

1985
Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen.
    Anesthesiology, 1981, Volume: 54, Issue:6

    Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cats; Clonidine; Drug Interactions; Electroshock; Female; Injections, Spinal; Macaca; Macaca mulatta; Male; Meperidine; Morphine; Naloxone; Narcotics; Pain; Phentolamine; Sensory Thresholds; Spinal Cord

1981
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
Clonidine therapy and meperidine withdrawal.
    The American journal of psychiatry, 1981, Volume: 138, Issue:5

    Topics: Adult; Clonidine; Female; Humans; Meperidine; Substance Withdrawal Syndrome

1981
Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?
    Molecular pharmacology, 1995, Volume: 47, Issue:1

    Topics: Adrenal Glands; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Clonidine; Cortodoxone; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desoxycorticosterone; Drug Interactions; Drug Therapy, Combination; Gene Expression Regulation; Isoenzymes; Kidney; Liver; Male; Meperidine; Molecular Sequence Data; Morphine; Neurosecretory Systems; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroids; Yohimbine

1995
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
    Clinical neuropharmacology, 1993, Volume: 16, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Meperidine; Methoxydimethyltryptamines; Neurotransmitter Agents; Yohimbine

1993
Clonidine premedication for induced hypotension with total intravenous anaesthesia for middle ear microsurgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Clonidine; Ear, Middle; Fentanyl; Heart Rate; Humans; Hypotension, Controlled; Meperidine; Microsurgery; Monitoring, Intraoperative; Preanesthetic Medication; Promethazine; Propofol

1994
Stability and compatibility of a meperidine-clonidine mixture in portable pump reservoirs for the management of cancer pain syndromes.
    Journal of pain and symptom management, 2006, Volume: 32, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Clonidine; Complex Mixtures; Drug Combinations; Drug Stability; Humans; Infusion Pumps; Meperidine; Neoplasms; Pain; Syndrome

2006
The effects of opioids, local anesthetics and adjuvants on isolated pregnant rat uterine muscles.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:4

    Topics: Alfentanil; Amides; Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Female; Isometric Contraction; Meperidine; Mepivacaine; Midazolam; Myometrium; Oxytocics; Oxytocin; Piperidines; Pregnancy; Rats; Rats, Wistar; Remifentanil; Ropivacaine; Uterine Contraction

2007
Meperidine, remifentanil and tramadol but not sufentanil interact with alpha(2)-adrenoceptors in alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor knock out mice brain.
    European journal of pharmacology, 2008, Mar-17, Volume: 582, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Affinity Labels; Analgesics, Opioid; Animals; Autoradiography; Binding, Competitive; Brain; Clonidine; Drug Partial Agonism; Female; In Vitro Techniques; Male; Meperidine; Mice; Mice, Knockout; Piperidines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Remifentanil; Sufentanil; Tramadol

2008