clonidine and mecamylamine

clonidine has been researched along with mecamylamine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's2 (9.52)18.2507
2000's7 (33.33)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Oparil, S; Rick, JH1
Ashbrook, DW; Purdy, RE1
Gala, RR; Lawson, DM1
Cosnier, D; Duchene-Marullaz, P; Grimal, J; Rispat, G; Streichenberger, G1
Cosnier, D; Labrid, C; Rispat, G; Streichenberger, G1
Fellhauer, M1
Dhasmana, KM; Fokker, WA; Spilker, BA1
Antonaccio, MJ; Povalski, HS; Robson, RD1
LoPachin, RM; Rudy, TA1
Baum, T; Moran, RM; Sabin, C1
Naguib, M; Yaksh, TL1
Bartolini, A; Bellucci, C; Dei, S; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Romanelli, MN; Scapecchi, S; Teodori, E1
Decker, MW; Meyer, MD; Rueter, LE1
Babaie, A; Etminani, A; Gharib, B; Homayoun, H; Zarrindast, MR1
Hama, AT; Lloyd, GK; Menzaghi, F1
Clemente Jiménez, M; Pérez Trullén, A1
Roddy, E1
Engelmann, JM; Gewirtz, JC; Radke, AK1
Alexander, JC; Bishnoi, M; Bruijnzeel, AW; Ford, J; Ji, Y; Rogers, JA; Scheick, S1
Ebbert, JO; Elrashidi, MY1

Reviews

4 review(s) available for clonidine and mecamylamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Current and future drug therapies for smoking cessation].
    Archivos de bronconeumologia, 2001, Volume: 37, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Anti-Anxiety Agents; Antidepressive Agents; Central Nervous System Stimulants; Chewing Gum; Clinical Protocols; Clonidine; Delayed-Action Preparations; Humans; Lobeline; Mecamylamine; Nebulizers and Vaporizers; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Polymethacrylic Acids; Polyvinyls; Smoking; Tobacco Use Cessation Devices

2001
Bupropion and other non-nicotine pharmacotherapies.
    BMJ (Clinical research ed.), 2004, Feb-28, Volume: 328, Issue:7438

    Topics: Administration, Inhalation; Adrenergic alpha-Agonists; Antidepressive Agents, Second-Generation; Bupropion; Clonidine; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Mecamylamine; Nicotine; Nicotinic Antagonists; Smoking Cessation

2004
Emerging drugs for the treatment of tobacco dependence: 2014 update.
    Expert opinion on emerging drugs, 2014, Volume: 19, Issue:2

    Topics: Atomoxetine Hydrochloride; Benzazepines; Bupropion; Clinical Trials as Topic; Clonidine; Humans; Mecamylamine; Nicotine; Nortriptyline; Propylamines; Quinoxalines; Tobacco Use Cessation Devices; Tobacco Use Disorder; Varenicline

2014

Other Studies

17 other study(ies) available for clonidine and mecamylamine

ArticleYear
Drug treatment of hypertension.
    Comprehensive therapy, 1977, Volume: 3, Issue:5

    Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Minoxidil; Nitroprusside; Prazosin; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympatholytics; Triamterene; Trimethaphan; Vasodilator Agents

1977
The evaluation of cardiovascular drugs in the anaesthetized, unrestrained rat.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:7

    Topics: Angiotensin II; Animals; Blood Pressure; Catheterization; Clonidine; Hydralazine; Jugular Veins; Male; Mecamylamine; Myocardium; Norepinephrine; Rats

1978
The influence of adrenergic, dopaminergic, cholinergic and serotoninergic drugs on plasma prolactin levels in ovariectomized, estrogen-treated rats.
    Endocrinology, 1975, Volume: 96, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Arecoline; Atropine; Castration; Clonidine; Dibenzothiepins; Dopamine; Estradiol; Female; Isoproterenol; Mecamylamine; Nicotine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Piperazines; Prolactin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Sulfides

1975
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; Guanethidine; Heart Rate; Hypertension; Injections, Intravenous; Male; Mecamylamine

1975
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:11

    Topics: Animals; Antihypertensive Agents; Aorta; Autonomic Nervous System; Blood Pressure; Cerebrovascular Circulation; Clonidine; Diuresis; Dogs; Female; Guanethidine; Hemodynamics; Hypertension; Imidazoles; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Myocardial Contraction; Rabbits; Rats; Regional Blood Flow; Seminal Vesicles; Toluidines; Vascular Resistance

1975
[Drug treatment of nicotine dependence].
    Medizinische Monatsschrift fur Pharmazeuten, 1990, Volume: 13, Issue:6

    Topics: Clonidine; Doxepin; Humans; Imipramine; Mecamylamine; Nicotine; Smoking; Substance Withdrawal Syndrome

1990
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan

1972
Modification by antihypertensive drugs of reflex circulatory responses induced by vertical tilting or bilateral carotid occlusion.
    European journal of pharmacology, 1973, Volume: 22, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Clonidine; Dibenzylchlorethamine; Dogs; Guanethidine; Heart Rate; Hydralazine; Hypertension, Renal; Mecamylamine; Postural Balance; Reflex; Reserpine; Stimulation, Chemical; Time Factors

1973
Sites and mechanism of action for the effects of intrathecal noradrenaline on thermoregulation in the rat.
    The Journal of physiology, 1983, Volume: 341

    Topics: Animals; Blood Pressure; Body Temperature Regulation; Brain; Clonidine; Injections, Spinal; Male; Mecamylamine; Norepinephrine; Rats; Spinal Cord; Sympathetic Nervous System

1983
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hydralazine; Hypotension; Male; Mecamylamine; Methyldopa; Minoxidil; Phentolamine; Posture; Prazosin; Propranolol; Rats; Reserpine; Sympathetic Nervous System

1981
Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Animals; Atropine; Behavior, Animal; Carbachol; Clonidine; Dose-Response Relationship, Drug; Edrophonium; Hot Temperature; Injections, Spinal; Male; Mecamylamine; Morphine; Neostigmine; Neuromuscular Blocking Agents; Pain Threshold; Premedication; Rats; Rats, Sprague-Dawley; Reaction Time

1994
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
    Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10

    Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Design; GABA Agonists; Mecamylamine; Mice; Molecular Structure; Muscarinic Antagonists; Nicotine; Nootropic Agents; Piperazines; Piracetam; Pyrroles; Scopolamine

2000
Spinal mechanisms underlying A-85380-induced effects on acute thermal pain.
    Brain research, 2000, Jul-28, Volume: 872, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Azetidines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intraperitoneal; Injections, Spinal; Lumbosacral Region; Male; Mecamylamine; Microdialysis; Muscarinic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Serotonin Antagonists; Spinal Cord

2000
Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice.
    European journal of pharmacology, 2000, Oct-27, Volume: 407, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anxiety; Atropine; Clonidine; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Yohimbine

2000
The antinociceptive effect of intrathecal administration of epibatidine with clonidine or neostigmine in the formalin test in rats.
    Pain, 2001, Volume: 91, Issue:1-2

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Drug Combinations; Formaldehyde; Injections, Spinal; Male; Mecamylamine; Neostigmine; Nicotinic Antagonists; Nociceptors; Pain; Pain Measurement; Palliative Care; Pyridines; Rats; Rats, Sprague-Dawley

2001
Potentiated startle as a measure of the negative affective consequences of repeated exposure to nicotine in rats.
    Psychopharmacology, 2009, Volume: 207, Issue:1

    Topics: Acoustic Stimulation; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reflex, Startle; Time Factors; Tobacco Use Disorder

2009
Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; Benzenesulfonates; Clonidine; Electrodes, Implanted; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prazosin; Quinolines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reward; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder

2012