clonidine has been researched along with maprotiline in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Schultheiss, A; Starke, K; Szabo, B | 1 |
| Nicholson, AN; Pascoe, PA | 1 |
| Laux, G; Lesch, KP; Mueller, T | 1 |
| Maj, J; Rogóź, Z; Skuza, G; Sowińska, H | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Starke, K; Wichmann, T | 1 |
| Feuerstein, TJ; Hertting, G; Jackisch, R | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Maj, J; Rogóz, Z; Skuza, G | 1 |
| Göthert, M; Köstermann, F; Schlicker, E | 1 |
| Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG | 1 |
| Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E | 1 |
| Amann, E; Gundert-Remy, U; Hildebrandt, R; Weber, E | 1 |
| Eckhardt, K; Feuerstein, TJ; Günter, T; Roth, P; Schmidt, S | 1 |
| Amelin, AV; Ignatov, IuD; Skoromets, AA | 1 |
| Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE | 1 |
2 review(s) available for clonidine and maprotiline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Current views on migraine and anti-migraine preparations].
Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antidepressive Agents; Aza Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Clonidine; Fluoxetine; Humans; Imidazoles; Maprotiline; Methysergide; Migraine Disorders; Mutation; Pizotyline; Placebos; Propranolol; Research; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sympatholytics; Vasoconstrictor Agents | 2003 |
2 trial(s) available for clonidine and maprotiline
| Article | Year |
|---|---|
Presynaptic alpha 2-adrenoceptor function and sleep in man: studies with clonidine and idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Clonidine; Dioxanes; Double-Blind Method; Humans; Idazoxan; Male; Maprotiline; Neurotransmitter Uptake Inhibitors; Norepinephrine; Receptors, Adrenergic, alpha; Sleep Stages | 1991 |
Lack of interaction between the tetracyclic antidepressant maprotiline and the centrally acting antihypertensive drug clonidine.
Topics: Adult; Anthracenes; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Maprotiline; Posture; Salivation | 1983 |
22 other study(ies) available for clonidine and maprotiline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (-)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Ganglia, Sympathetic; Heart Rate; Kidney; Maprotiline; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Stereoisomerism; Sympathetic Nervous System; Yohimbine | 1991 |
Alpha 2-adrenoceptor responsivity in depression: effect of chronic treatment with moclobemide, a selective MAO-A-inhibitor, versus maprotiline.
Topics: Adult; Benzamides; Clonidine; Depressive Disorder; Female; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Maprotiline; Middle Aged; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales; Receptors, Adrenergic, alpha | 1990 |
Some central pharmacological effects of (+)- and (-)-oxaprotiline.
Topics: Animals; Anthracenes; Apomorphine; Behavior, Animal; Clonidine; Dopamine; Hypothermia; Male; Maprotiline; Mice; Motor Activity; Rats; Rats, Inbred Strains; Reserpine; Stereoisomerism | 1990 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Uptake, release, and modulation of release of noradrenaline in rabbit superior colliculus.
Topics: Animals; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Male; Maprotiline; Norepinephrine; Rabbits; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Neurotransmitter; Serotonin; Superior Colliculi; Tetrodotoxin | 1988 |
Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT-receptor agonists.
Topics: Animals; Clonidine; Hippocampus; In Vitro Techniques; Maprotiline; Norepinephrine; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Serotonin; Yohimbine | 1985 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
(+)-Oxaprotiline but not (-)-oxaprotiline given chronically potentiates the aggressive behaviour induced by clonidine.
Topics: Aggression; Animals; Anthracenes; Antidepressive Agents; Clonidine; Drug Synergism; Humans; Isomerism; Male; Maprotiline; Mice | 1983 |
Relationship between transmitter uptake inhibition and effects of alpha-adrenoceptor agonists on serotonin and noradrenaline release in the rat brain cortex.
Topics: Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Clonidine; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tritium | 1983 |
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats.
Topics: Animals; Anthracenes; Blood Vessels; Cardiovascular System; Clonidine; Desipramine; Dibenzazepines; Drug Interactions; Heart; Male; Maprotiline; Mianserin; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord | 1980 |
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergism; Fluoxetine; Humans; Male; Maprotiline; Mice; Zimeldine | 1981 |
Differential effects of K(ATP) channel blockers on [(3)H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Autoreceptors; Clonidine; Desipramine; Drug Interactions; Glyburide; In Vitro Techniques; Male; Maprotiline; Neocortex; Norepinephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Modelling the anxiety-depression continuum in chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiazepoxide; Clonidine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Interleukin-6; Maprotiline; Social Isolation; Stress, Psychological | 2009 |