Compounds > clonidine

clonidine and loperamide

clonidine has been researched along with loperamide in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.67)	18.7374
1990's	2 (13.33)	18.2507
2000's	5 (33.33)	29.6817
2010's	7 (46.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bertholet, A; Buchheit, KH	1
Ishii, A; Karasawa, A; Kishibayashi, N; Takasaki, K	1
Onoda, Y; Yamada, K	1
Doihara, H; Ito, H; Kawabata-Shoda, E; Kojima, R; Nozawa, K; Yokoyama, T	1
Gould, M; Sellin, JH	1
Chen, J; Chen, P; Jia, P; Xiu, A; Zhan, Y; Zhang, J; Zhao, Y; Zhou, M	1
Doihara, H; Itou, H; Kaku, H; Keto, Y; Kojima, R; Nozawa, K; Yokoyama, T	1
Castagné, V; Goineau, S; Guillaume, P	1
Barnett, BS; Suzuki, J; Ward, HB	1

Reviews

1 review(s) available for clonidine and loperamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

14 other study(ies) available for clonidine and loperamide

Article	Year
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nature chemical biology, 2008, Volume: 4, Issue:5 Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Inhibition of small intestine motility by cromakalim (BRL 34915). European journal of pharmacology, 1988, Sep-23, Volume: 154, Issue:3 Topics: Animals; Benzopyrans; Clonidine; Cromakalim; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Intestine, Small; Loperamide; Male; Mice; Peristalsis; Potassium Channels; Pyrroles	1988
Effects of KW-5092, a novel gastroprokinetic agent, on the delayed colonic propulsion in rats. Japanese journal of pharmacology, 1994, Volume: 65, Issue:1 Topics: Animals; Clonidine; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Imidazoles; Loperamide; Male; Nitriles; Rats; Rats, Sprague-Dawley; Stimulation, Chemical	1994
Comparison of the effects of T-1815, yohimbine and naloxone on mouse colonic propulsion. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1993, Volume: 29, Issue:2 Topics: Administration, Oral; Animals; Clonidine; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Loperamide; Male; Mice; Naloxone; Propylamines; Thiophenes; Yohimbine	1993
Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models. Pharmacology, 2009, Volume: 84, Issue:4 Topics: Animals; Atropine; Clonidine; Constipation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Indoles; Loperamide; Male; Mice; Mice, Inbred Strains; Mustard Plant; Naloxone; Plant Oils; Transient Receptor Potential Channels; TRPA1 Cation Channel; Yohimbine	2009
Diabetic diarrhea. Current gastroenterology reports, 2009, Volume: 11, Issue:5 Topics: Algorithms; Antidiarrheals; Celiac Disease; Clonidine; Colitis; Diabetes Complications; Diabetes Mellitus, Type 2; Diarrhea; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Incidence; Loperamide; Metformin; Octreotide; Prevalence; Risk Factors; Sweetening Agents; Texas; Treatment Outcome	2009
Laxative effects of Salecan on normal and two models of experimental constipated mice. BMC gastroenterology, 2013, Mar-20, Volume: 13 Topics: Animals; beta-Glucans; Clonidine; Constipation; Defecation; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Laxatives; Loperamide; Male; Mice; Mice, Inbred ICR; Treatment Outcome	2013
Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain. European journal of pharmacology, 2014, Jan-15, Volume: 723 Topics: Abdominal Pain; Analgesics; Animals; Calcium; Calcium Channels; Clonidine; Colon; Constipation; Gastrointestinal Transit; HEK293 Cells; Humans; Indoleacetic Acids; Loperamide; Male; Mice; Nerve Tissue Proteins; Rats; Rats, Wistar; Serotonin; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; Visceral Pain	2014
Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1 Topics: Acetaminophen; Animals; Clonidine; Gastric Emptying; Gastric Mucosa; Intestine, Small; Loperamide; Male; Metoclopramide; Phenolsulfonphthalein; Rats; Rats, Wistar	2015
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report. Substance abuse, 2019, Volume: 40, Issue:2 Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics	2019