clonidine and ketorolac

clonidine has been researched along with ketorolac in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's10 (41.67)29.6817
2010's10 (41.67)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Malmberg, AB; Yaksh, TL1
Akopian, RG; Daĭkhes, NA; Davudov, KhSh; Gur'ianov, VA; Kokliaeva, NV; Kuĭian, SM; Nazhmudinov, II; Pogosov, VS; Riazanov, VB; Tiukov, VL1
Rattan, AK; Tejwani, GA1
Johnson, CN1
Conklin, DR; Eisenach, JC1
Elder, JS; Palmer, JS; Thomas, S; Tripi, PA1
Adams, MJ; Dalury, DF; Kelley, TC; Mulliken, BD1
Davis, AB; Rivey, MP; Tietje, T1
Carreon, LY; Collis, PN; Huang, J; Hunter, AM; Malkani, AL; Vaughn, MD1
Danoff, JR; Fraser, J; Goel, R; Henderson, RA; Sharkey, PF1
De Kock, M; Dewe, G; Forget, P; Lois, F; Reding, R; Steyaert, A1
Casambre, FD; Della Valle, CJ; Fillingham, YA; Hamilton, WG; Hannon, CP; Kamath, AF; Karas, V; Nelson, N; Spangehl, MJ; Verity, TJ1
Bhenderu, LS; Desai, R; Huang, JH; Lyon, KA; Rahm, M; Richardson, W; Soto, JM1

Reviews

3 review(s) available for clonidine and ketorolac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Intravenous regional anesthesia: new approaches to an old technique.
    CRNA : the clinical forum for nurse anesthetists, 2000, Volume: 11, Issue:2

    Topics: Adjuvants, Anesthesia; Analgesics; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Humans; Ketorolac; Meperidine; Nurse Anesthetists; Tourniquets

2000
The Efficacy and Safety of Periarticular Injection in Total Joint Arthroplasty: A Direct Meta-Analysis.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:10

    Topics: Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Clonidine; Epinephrine; Humans; Injections, Intra-Articular; Ketorolac; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine

2022

Trials

4 trial(s) available for clonidine and ketorolac

ArticleYear
Clonidine increases duration of bupivacaine caudal analgesia for ureteroneocystostomy: a double-blind prospective trial.
    The Journal of urology, 2005, Volume: 174, Issue:3

    Topics: Analgesics; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Clonidine; Cystostomy; Double-Blind Method; Drug Synergism; Female; Fentanyl; Humans; Infant; Infusions, Intravenous; Ketorolac; Male; Morphine; Nerve Block; Pain, Postoperative; Prospective Studies; Sympatholytics; Vesico-Ureteral Reflux

2005
Efficacy of multimodal perioperative analgesia protocol with periarticular medication injection in total knee arthroplasty: a randomized, double-blinded study.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Amides; Analgesics; Arthroplasty, Replacement, Knee; Clonidine; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Humans; Injections, Intra-Articular; Ketorolac; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Perioperative Care; Ropivacaine

2013
Periarticular Injection After Total Knee Arthroplasty Using Liposomal Bupivacaine vs a Modified Ranawat Suspension: A Prospective, Randomized Study.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:3

    Topics: Aged; Amides; Analgesics; Arthroplasty, Replacement, Knee; Bupivacaine; Clonidine; Epinephrine; Female; Humans; Injections; Ketorolac; Liposomes; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine

2016
Periarticular Ropivacaine Cocktail Is Equivalent to Liposomal Bupivacaine Cocktail in Bilateral Total Knee Arthroplasty.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:8

    Topics: Adult; Aged; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Clonidine; Double-Blind Method; Epinephrine; Female; Humans; Injections, Intra-Articular; Ketorolac; Knee Joint; Liposomes; Male; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine

2018

Other Studies

17 other study(ies) available for clonidine and ketorolac

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50488H, and L-PIA on the formalin test and an isobolographic analysis of the NSAID interaction.
    Anesthesiology, 1993, Volume: 79, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Combinations; Drug Interactions; Formaldehyde; Ketorolac; Male; Morphine; Motor Activity; Nociceptors; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tolmetin

1993
[Use of nonopiate agents for anesthesia in ENT patients at high surgical-anesthesiological risk].
    Vestnik otorinolaringologii, 1998, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Endotracheal; Anti-Anxiety Agents; Aprotinin; Child; Clonidine; Evaluation Studies as Topic; Female; Hemostatics; Humans; Ketorolac; Male; Middle Aged; Neuroleptanalgesia; Otorhinolaryngologic Diseases; Otorhinolaryngologic Neoplasms; Risk Factors; Tolmetin; Tranylcypromine

1998
Antagonism of antinociception produced by intrathecal clonidine by ketorolac in the rat: the role of the opioid system.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:5

    Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Ketorolac; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord

2000
Intrathecal ketorolac enhances antinociception from clonidine.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergism; Hot Temperature; Injections, Spinal; Ketorolac; Male; Pain Measurement; Rats; Time Factors

2003
Comparison of 2 Methods of Local Anesthetic-Based Injection as Part of a Multimodal Approach to Pain Management After Total Knee Arthroplasty.
    Journal of pharmacy practice, 2015, Volume: 28, Issue:6

    Topics: Aged; Amides; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Bupivacaine; Clonidine; Drug Administration Routes; Drug Therapy, Combination; Epinephrine; Female; Humans; Ketorolac; Length of Stay; Male; Montana; Pain Management; Postoperative Nausea and Vomiting; Retrospective Studies; Ropivacaine; Vasoconstrictor Agents

2015
Pain management in living related adult donor hepatectomy: feasibility of an evidence-based protocol in 100 consecutive donors.
    BMC research notes, 2018, Nov-26, Volume: 11, Issue:1

    Topics: Adult; Analgesia, Epidural; Anesthesia, Intravenous; Anesthetics; Clonidine; Evidence-Based Medicine; Female; Follow-Up Studies; Hepatectomy; Humans; Ketamine; Ketorolac; Laparotomy; Living Donors; Magnesium Sulfate; Male; Pain Management; Pain, Postoperative; Postoperative Period; Pregabalin; Premedication; Retrospective Studies

2018
Ropivacaine-Epinephrine-Clonidine-Ketorolac Cocktail as a Local Anesthetic for Lumbar Decompression Surgery: A Single Institutional Experience.
    World neurosurgery, 2023, Volume: 176

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Clonidine; Decompression; Epinephrine; GPI-Linked Proteins; Humans; Ketorolac; Lumbar Vertebrae; Morphine Derivatives; Opioid-Related Disorders; Pain, Postoperative; Retrospective Studies; Ropivacaine

2023