clonidine has been researched along with ketamine in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (6.82) | 18.7374 |
| 1990's | 19 (21.59) | 18.2507 |
| 2000's | 28 (31.82) | 29.6817 |
| 2010's | 30 (34.09) | 24.3611 |
| 2020's | 5 (5.68) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Bloch, R; Bousquet, P; Feldman, J; Gaertner, M | 1 |
| Kaukinen, S | 2 |
| Carlsson, A; Carlsson, M; Svensson, A | 1 |
| Carlsson, M; Svensson, A | 1 |
| Pezzola, A; Popoli, P; Scotti de Carolis, A | 1 |
| McCann, DJ; Rabin, RA; Winter, JC | 1 |
| Burks, TF; Galligan, JJ | 1 |
| Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH | 1 |
| Rawal, N | 1 |
| Desmonts, JM; Henzel, D; Laudenbach, V; Lecharny, JB; Mantz, J; Peytavin, G | 1 |
| Nishikawa, T; Tanaka, M | 1 |
| Doak, GJ; Duke, PC | 1 |
| Munro, HM; Paxton, LD; Sleigh, JW | 1 |
| Aldridge, LA; Cook, B; Doyle, E; Grubb, DJ | 1 |
| Lemos, D; Muller, A | 1 |
| Tryba, M | 1 |
| Cook, B; Doyle, E | 1 |
| Abdel-Rahman, AA; el-Mas, MM | 1 |
| Aantaa, R; Kanto, JH; Kirvelä, OA; Taittonen, MT | 1 |
| Asada, A; Kariya, N; Nishi, S; Shindoh, M; Yukioka, H | 1 |
| Amabeoku, GJ | 1 |
| Farber, NB; Kim, SH; Olney, JW; Price, MT | 1 |
| Krause, T; Paris, A; Scholz, J; Steinfath, M; Tonner, PH; von Knobelsdorff, G; Wappler, F | 1 |
| Anzawa, N; Hirota, K; Kubota, T; Kushikata, T; Matsuki, A; Ohkawa, H; Takahashi, S; Yoshida, H | 1 |
| Handa, F; Nishikawa, T; Tanaka, M; Toyooka, H | 1 |
| Friedberg, BL; Sigl, JC | 1 |
| Morton, NS | 1 |
| De Negri, P; De Vivo, P; Ivani, G; Visconti, C | 1 |
| Adler, L; Hager, H; Kettner, S; Marhofer, P; Semsroth, M; Sitzwohl, C | 1 |
| Baker, AK; Hoffmann, VL; Meert, TF | 1 |
| Eck, JB; Ross, AK | 1 |
| Eisenach, JC; Yaksh, TL | 1 |
| de Beer, DA; Thomas, ML | 1 |
| Alsheimer, M; Koppert, W; Scheuber, K; Schmelz, M; Schüttler, J; Sittl, R | 1 |
| Holmfred, A | 1 |
| Bertelli, JA; Calixto, JB; Campos, MM; Ferreira, J; Rodrigues-Filho, R; Santos, AR | 1 |
| Almenrader, N; Canneti, A; Haiberger, R; Passariello, M; Pietropaoli, P; Rubeo, L | 1 |
| Lauretti, GR; Mattos, AL; Paccola, CA; Rodrigues, AM | 1 |
| Dalsasso, M; Innocente, F; Ori, C; Tresin, P; Veronese, S | 1 |
| Adams, HA; Benrath, J; Gustorff, B; Kress, HG; Scharbert, G | 1 |
| Gordeev, VI; Kachalova, EG; Mokhammed Khusseĭn, IaIa; Ul'rikh, GE | 1 |
| Akbas, H; Akbas, M; Sahin, N; Titiz, TA; Yegin, A | 1 |
| Inomata, S; Kakiuchi, Y; Kohda, Y; Miyabe, M; Ohara, Y; Osaka, Y; Sukegawa, I; Toyooka, H | 1 |
| Buvanendran, A; Kroin, JS | 1 |
| Buvanendran, A; Reuben, SS | 1 |
| Guo, QL; He, ZH; Huang, CS; Zou, WY | 1 |
| Freitag, M; Gottschalk, A; Kreissl, S; Rempf, C; Standl, T; Staude, HJ; Steinacker, E; Strate, T | 1 |
| Black, IH; Malchow, RJ | 1 |
| Prommer, EE | 1 |
| Collet, V; De Kock, M; Forget, P; Lavand'homme, P | 1 |
| Congedo, E; De Cosmo, G; Sgreccia, M | 1 |
| Bonati, M; Clavenna, A; Fortinguerra, F; Maschi, S | 1 |
| Kasaba, T | 1 |
| Barvais, L; Engelman, E; Hecquet, F; Salengros, JC; Sekkat, J; Touihri, K | 1 |
| Eriksson, P; Fredriksson, A; Gordh, T; Pontén, E; Viberg, H | 1 |
| Hess, L; Horacek, J; Kurzova, A; Malek, J; Palenicek, T; Scigel, V | 1 |
| Bollag, L; Landau, R; Ortner, C | 1 |
| Goyagi, T; Nishikawa, T; Nitta, R | 1 |
| Colby, CE; Nemergut, ME; Yaster, M | 1 |
| Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW | 1 |
| Albrecht, M; Bein, B; Feng, Z; Ohnesorge, H; Steinfath, M; Zitta, K | 1 |
| Bailard, NS; Flores, RA; Ortiz, J | 1 |
| Pretto, G; Silva, E; Westphal, GA | 1 |
| Drummond, PD; Finch, PM | 1 |
| Banov, D; Bassani, AS | 1 |
| Russo, MA; Santarelli, DM | 1 |
| Farber, NB; Kharasch, E; Lenze, EJ; Newcomer, JW; Olney, J; Schweiger, J; Yingling, M | 1 |
| Lönnqvist, PA; Lundblad, M | 1 |
| Garg, P; Kothari, J; Pandya, H; Patel, J; Thosani, R | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
| Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S | 1 |
| Anghelescu, DL; Moore, AD | 1 |
| Hainz, N; Kovačević, B; Meier, C; Rzagalinski, I; Tschernig, T; Volmer, DA | 1 |
| De Kock, M; Dewe, G; Forget, P; Lois, F; Reding, R; Steyaert, A | 1 |
| Bedon-Carte, S; Bello, M; Leo, F; Oger, S; Ouattara, A; Vielstadte, C; Zaouter, C | 1 |
| Sun, S; Tan, D; Wang, F; Xia, H | 1 |
| Ances, BM; Farber, NB; Kharasch, ED; Lenze, EJ; Nicol, GE; Palanca, BJA; Schweiger, JA; Siegel, JS; Snyder, AZ; Yingling, MD | 1 |
| Huang, RR; Li, YL; Qu, SS; Yang, CQ; Yu, KH; Zhang, JM | 1 |
| Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN | 1 |
| Gadepalli, RS; Rimoldi, JM; Smith, SJ; Squires, GD; Sufka, KJ; White, SW; Wright, GM | 1 |
20 review(s) available for clonidine and ketamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Spinal antinociception: clinical aspects.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Ketamine; Neurons, Afferent; Nociceptors; Octreotide; Pain; Somatostatin; Spinal Cord | 1995 |
The use of additives to local anaesthetic solutions for caudal epidural blockade.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Clonidine; Epinephrine; Humans; Ketamine; Vasoconstrictor Agents | 1996 |
Paediatric regional anaesthesia--what makes a difference?
Topics: Ambulatory Surgical Procedures; Anesthesia, Caudal; Anesthesia, Conduction; Anesthetics, Local; Child; Clonidine; Humans; Ketamine; Nerve Block | 2002 |
Caudal additives in children--solutions or problems?
Topics: Adjuvants, Anesthesia; Analgesics; Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; Child; Clonidine; Humans; Ketamine | 2003 |
Useful adjuvants for postoperative pain management.
Topics: Amines; Clonidine; Cyclohexanecarboxylic Acids; Dexamethasone; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Neostigmine; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate | 2007 |
Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement; Chronic Disease; Clonidine; Complex Regional Pain Syndromes; Cyclooxygenase 2 Inhibitors; Humans; Hyperalgesia; Inflammation Mediators; Ketamine; Neuronal Plasticity; Orthopedics; Pain Threshold; Pain, Postoperative; Phantom Limb | 2007 |
The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Clonidine; Critical Care; Critical Illness; Drug Therapy, Combination; Global Health; Humans; Ketamine; Military Medicine; Multiple Trauma; Pain; Pain Management; Pain Measurement; Practice Guidelines as Topic; Risk Factors; Terrorism; Treatment Outcome; United States | 2008 |
New drugs for epidural analgesia.
Topics: Analgesia, Epidural; Analgesics; Clonidine; Dexmedetomidine; Humans; Ketamine; Neostigmine | 2009 |
Pain management in the paediatric population: the regulatory situation in Europe.
Topics: Adolescent; Analgesics; Buprenorphine; Child; Child, Preschool; Clonidine; Drug and Narcotic Control; Europe; Humans; Infant; Infant, Newborn; Ketamine; Pain; Practice Guidelines as Topic; Randomized Controlled Trials as Topic | 2010 |
[Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia].
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Dexmedetomidine; Droperidol; Drug Compounding; Epinephrine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium Sulfate; Midazolam; Morphine; Neostigmine | 2010 |
Chronic pain after childbirth.
Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarean Section; Chronic Pain; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Ketamine; Magnesium Sulfate; Nerve Block; Oxytocin; Pain, Postoperative; Parturition; Pelvic Pain; Peritoneum; Pregabalin; Pregnancy; Risk Factors; Uterus | 2013 |
Sedation and analgesia to facilitate mechanical ventilation.
Topics: Analgesics; Analgesics, Opioid; Benzodiazepines; Clonidine; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Intensive Care, Neonatal; Intubation, Intratracheal; Ketamine; Midazolam; Neuromuscular Blockade; Pain; Pain Management; Pain Measurement; Respiration, Artificial | 2013 |
Additives to local anesthetics for peripheral nerve blocks: Evidence, limitations, and recommendations.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Buprenorphine; Clonidine; Dexamethasone; Dexmedetomidine; Drug Combinations; Epinephrine; Evidence-Based Medicine; Humans; Ketamine; Magnesium Compounds; Midazolam; Nerve Block; Peripheral Nerves; Sodium Bicarbonate; Tramadol; Vasoconstrictor Agents | 2014 |
Topical treatment in pain medicine: from ancient remedies to modern usage.
Topics: Administration, Cutaneous; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Clonidine; Cocaine; Epidermis; History, 18th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Ketamine; Mandragora; Menthol; Nociception; Pain Management; Plant Extracts | 2015 |
Adjunct analgesic drugs to local anaesthetics for neuroaxial blocks in children.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Analgesics; Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; Child; Clonidine; Epinephrine; Evidence-Based Medicine; Humans; Injections, Spinal; Ketamine; Nerve Block | 2016 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence Delirium; Fentanyl; Humans; Incidence; Isoflurane; Ketamine; Methyl Ethers; Propofol; Sevoflurane | 2017 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theorem; Child; Clonidine; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Humans; Ketamine; Midazolam; Network Meta-Analysis; Ophthalmologic Surgical Procedures; Propofol; Psychomotor Agitation; Remifentanil; Sevoflurane; Sufentanil | 2019 |
Comparison of different sedatives in children before general anaesthesia for selective surgery: A network meta-analysis.
Topics: Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Ketamine; Melatonin; Midazolam; Network Meta-Analysis | 2022 |
21 trial(s) available for clonidine and ketamine
| Article | Year |
|---|---|
Oral clonidine premedication attenuates the hypertensive response to ketamine.
Topics: Administration, Oral; Adolescent; Adult; Anesthesia, Intravenous; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Ketamine; Male; Middle Aged; Premedication | 1994 |
Oral clonidine premedication attenuates the haemodynamic effects associated with ketamine anaesthetic induction in humans.
Topics: Administration, Oral; Adult; Anesthesia, Intravenous; Blood Pressure; Clonidine; Diazepam; Double-Blind Method; Female; Hallucinations; Heart Rate; Hemodynamics; Humans; Ketamine; Male; Patient Satisfaction; Placebos; Preanesthetic Medication; Time Factors | 1993 |
The cardiovascular response to ketamine: the effects of clonidine and lignocaine.
Topics: Adult; Aged; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Ketamine; Lidocaine; Male; Middle Aged; Surgical Procedures, Operative; Tachycardia | 1993 |
Comparison of the effects of adrenaline, clonidine and ketamine on the duration of caudal analgesia produced by bupivacaine in children.
Topics: Analgesia; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Clonidine; Cryptorchidism; Drug Therapy, Combination; Epinephrine; Humans; Infant; Ketamine; Male; Pain, Postoperative; Postoperative Period; Sympatholytics; Sympathomimetics | 1995 |
The effect of clonidine or midazolam premedication on perioperative responses during ketamine anesthesia.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Blood Pressure; Carbon Dioxide; Clonidine; Double-Blind Method; Drug Interactions; Epinephrine; Female; Heart Rate; Humans; Ketamine; Male; Midazolam; Middle Aged; Norepinephrine; Oxygen; Oxygen Consumption; Placebos; Premedication | 1998 |
Effects of oral clonidine premedication on side effects of intravenous ketamine anesthesia: a randomized, double-blind, placebo-controlled study.
Topics: Administration, Oral; Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Blood Pressure; Clonidine; Double-Blind Method; Dreams; Female; Heart Rate; Humans; Incidence; Intubation, Intratracheal; Ketamine; Male; Monitoring, Intraoperative; Nitrous Oxide; Oxygen; Placebos; Postoperative Complications; Premedication; Prospective Studies; Salivation; Sympatholytics | 2000 |
How to prolong postoperative analgesia after caudal anaesthesia with ropivacaine in children: S-ketamine versus clonidine.
Topics: Adrenergic alpha-Agonists; Amides; Analgesia, Epidural; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Local; Child; Child, Preschool; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Infant; Ketamine; Pain, Postoperative; Prospective Studies; Respiratory Mechanics; Ropivacaine | 2001 |
Caudal clonidine prolongs analgesia from caudal S(+)-ketamine in children.
Topics: Analgesia; Anesthesia, Caudal; Child; Child, Preschool; Clonidine; Double-Blind Method; Humans; Infant; Ketamine; Prospective Studies | 2002 |
Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Half-Life; Humans; Hyperalgesia; Infusions, Intravenous; Ketamine; Male; Oxygen; Pain Measurement; Physical Stimulation; Piperidines; Receptors, Opioid, mu; Remifentanil; Substance Withdrawal Syndrome | 2003 |
Caudal analgesia in children: S(+)-ketamine vs S(+)-ketamine plus clonidine.
Topics: Adrenergic alpha-Agonists; Analgesia; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Dissociative; Child, Preschool; Clonidine; Female; Hemodynamics; Hernia, Inguinal; Humans; Infant; Ketamine; Male; Monitoring, Intraoperative; Pain Measurement; Pain, Postoperative; Stereoisomerism; Testicular Hydrocele | 2004 |
The combination of epidural clonidine and S(+)-ketamine did not enhance analgesic efficacy beyond that for each individual drug in adult orthopedic surgery.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics; Clonidine; Double-Blind Method; Drug Synergism; Female; Humans; Ketamine; Male; Middle Aged; Orthopedic Procedures; Pain, Postoperative | 2005 |
Low-dose ketamine with clonidine and midazolam for adult day care surgery.
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clonidine; Female; Hemodynamics; Humans; Ketamine; Male; Midazolam; Middle Aged; Postoperative Nausea and Vomiting; Respiratory Function Tests | 2005 |
Comparison of the effects of clonidine and ketamine added to ropivacaine on stress hormone levels and the duration of caudal analgesia.
Topics: Adjuvants, Anesthesia; Aging; Amides; Anesthesia, Caudal; Anesthetics, Dissociative; Anesthetics, Local; Blood Glucose; Body Weight; Child; Child, Preschool; Clonidine; Female; Hemodynamics; Hormones; Humans; Hydrocortisone; Insulin; Ketamine; Male; Ropivacaine | 2005 |
Pre-incisional epidural ropivacaine, sufentanil, clonidine, and (S)+-ketamine does not provide pre-emptive analgesia in patients undergoing major pancreatic surgery.
Topics: Adult; Aged; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Stability; Female; Humans; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Pancreas; Prospective Studies; Ropivacaine; Sufentanil | 2008 |
Low-dose intravenous ketamine and clonidine for poor postoperative opioid responsiveness: a double blind randomized study.
Topics: Analgesics; Analgesics, Opioid; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Pirinitramide; Postoperative Period; Prospective Studies; Sodium Chloride; Treatment Outcome | 2011 |
The influence of clonidine on oral ketamine-midazolam premedication in intellectually disabled patients indicated for dental procedures: double-blind comparison of two sedation regimes.
Topics: Adult; Anesthesia, Dental; Clinical Protocols; Clonidine; Dental Care for Disabled; Disabled Persons; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Intellectual Disability; Ketamine; Male; Midazolam; Middle Aged; Preanesthetic Medication; Treatment Outcome | 2012 |
Combination of oral clonidine and intravenous low-dose ketamine reduces the consumption of postoperative patient-controlled analgesia morphine after spine surgery.
Topics: Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Clonidine; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Morphine; Pain, Postoperative; Spine; Visual Analog Scale | 2013 |
Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Anti-Anxiety Agents; Bandages; Burns; Clonidine; Debridement; Dissociative Disorders; Double-Blind Method; Female; Humans; Ketamine; Male; Midazolam; Middle Aged; Severity of Illness Index; Young Adult | 2014 |
Ninety-six hour ketamine infusion with co-administered clonidine for treatment-resistant depression: A pilot randomised controlled trial.
Topics: Adult; Antidepressive Agents; Clonidine; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Female; Humans; Infusions, Intravenous; Ketamine; Linear Models; Male; Middle Aged; Pilot Projects; Psychiatric Status Rating Scales; Treatment Outcome; United States | 2016 |
Clonidine and ketamine for stable hemodynamics in off-pump coronary artery bypass.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Analgesics, Opioid; Anesthetics, Dissociative; Blood Pressure; Clonidine; Coronary Artery Bypass, Off-Pump; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; India; Ketamine; Length of Stay; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Sympatholytics; Time Factors; Treatment Outcome | 2016 |
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution | 2022 |
47 other study(ies) available for clonidine and ketamine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
[Variations in the effect of clonidine on arterial pressure in rats in the presence of various anesthetics].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Blood Pressure; Chloralose; Clonidine; Ketamine; Male; Pentobarbital; Progesterone; Rats; Urethane | 1977 |
Effects of antihypertensive medication on the cardiovascular response to ketamine in rats.
Topics: Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Clonidine; Heart Rate; Hemodynamics; Hydralazine; Infusions, Parenteral; Injections, Intraperitoneal; Ketamine; Male; Methyldopa; Propranolol; Rats; Vasomotor System | 1978 |
The combined effects of antihypertensive drugs and anaesthetics (halothane and ketamine) on the isolated heart.
Topics: Animals; Antihypertensive Agents; Clonidine; Coronary Circulation; Dose-Response Relationship, Drug; Halothane; Heart; Heart Rate; Hemodynamics; Hydralazine; Ketamine; Male; Methyldopa; Myocardial Contraction; Perfusion; Propranolol; Rabbits | 1978 |
Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Biperiden; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methyldopa; Mice; Mice, Neurologic Mutants; Motor Activity; N-Methylaspartate; Parasympatholytics; Parkinson Disease; Piperazines | 1991 |
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems.
Topics: Animals; Aspartic Acid; Atropine; Biogenic Monoamines; Clonidine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Glutamates; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission | 1990 |
An EEG and behavioural study on the interactions of clonidine with phencyclidine and ketamine in rats.
Topics: Animals; Brain; Clonidine; Drug Interactions; Electroencephalography; Ketamine; Male; Muscle Tonus; Phencyclidine; Prazosin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1990 |
Interactions of clonidine with phencyclidine and ketamine: studies of radial maze performance and righting reflex in rats.
Topics: Anesthesia; Animals; Behavior, Animal; Clonidine; Drug Interactions; Ketamine; Learning; Male; Phencyclidine; Rats; Rats, Inbred F344; Reflex | 1987 |
Effects of centrally and peripherally administered clonidine on small intestinal transit in the rat.
Topics: Animals; Clonidine; Female; Gastrointestinal Motility; Injections, Intraperitoneal; Injections, Intraventricular; Ketamine; Rats; Rats, Inbred Strains | 1983 |
Narcotic discrimination in pigeons.
Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity | 1980 |
Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes.
Topics: Anesthetics; Animals; Biological Transport; Clonidine; Corpus Striatum; Enflurane; Etomidate; gamma-Aminobutyric Acid; Halothane; In Vitro Techniques; Isoflurane; Ketamine; Male; Nipecotic Acids; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Synaptosomes; Thiopental | 1995 |
[Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture].
Topics: Aged; Analgesics; Catheters, Indwelling; Clonidine; Drug Combinations; Drug Synergism; Female; Humans; Infusion Pumps; Injections, Spinal; Ketamine; Lidocaine; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain Management | 1996 |
Choices in sedation: the balanced sedation technique.
Topics: Anesthesia, Conduction; Clonidine; Conscious Sedation; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Propofol | 1996 |
Contrasting effects of urethane, ketamine, and thiopental anesthesia on ethanol-clonidine hemodynamic interaction.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Interactions; Ethanol; Heart Rate; Hemodynamics; Ketamine; Male; Rats; Rats, Sprague-Dawley; Thiopental; Urethane | 1997 |
Oral clonidine for sedation and analgesia in a burn patient.
Topics: Administration, Oral; Analgesics; Burns; Clonidine; Humans; Hypnotics and Sedatives; Ketamine; Male; Middle Aged | 1998 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Clonidine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ketamine; Microdialysis; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, GABA; Receptors, N-Methyl-D-Aspartate | 1999 |
[Interactions of intravenous anesthetics with cerebral alpha-2-adrenoceptors].
Topics: Adrenergic alpha-Agonists; Affinity Labels; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Autoradiography; Binding, Competitive; Brain; Clonidine; In Vitro Techniques; Ketamine; Propofol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1999 |
Inhibitory effect of clonidine on ketamine-induced norepinephrine release from the medial prefrontal cortex in rats.
Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Animals; Central Nervous System; Clonidine; Ketamine; Male; Norepinephrine; Prefrontal Cortex; Rats | 1999 |
Clonidine premedication decreases propofol consumption during bispectral index (BIS) monitored propofol-ketamine technique for office-based surgery.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Anesthetics, Intravenous; Antihypertensive Agents; Clonidine; Drug Administration Schedule; Female; Humans; Ketamine; Middle Aged; Preanesthetic Medication; Propofol; Rhytidoplasty | 2000 |
Ropivacaine in children.
Topics: Amides; Anesthesia, Caudal; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Clonidine; Drug Administration Schedule; Humans; Infant; Ketamine; Ropivacaine; Treatment Outcome | 2000 |
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Clonidine; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Ketamine; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Opioid | 2002 |
Epidural ketamine in healthy children--what's the point?
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Dissociative; Child; Clonidine; Humans; Ketamine; Risk | 2003 |
Failed intrathecal analgesia following severe, terminal cancer pain.
Topics: Amines; Analgesics; Anesthetics, Local; Back Pain; Bupivacaine; Catheterization; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Melanoma; Middle Aged; Morphine; Severity of Illness Index; Skin Neoplasms; Spinal Cord Neoplasms; Terminal Care; Tomography, X-Ray Computed; Treatment Failure | 2004 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides | 2004 |
Long-term intrathecal S(+)-ketamine in a patient with cancer-related neuropathic pain.
Topics: Analgesics; Clonidine; Drug Tolerance; Humans; Injections, Spinal; Ketamine; Lumbar Vertebrae; Male; Middle Aged; Morphine; Pain, Intractable; Palliative Care; Spinal Neoplasms; Time Factors; Urethral Neoplasms | 2005 |
[Effects of induction of anesthesia on hemodynamics in children with deformities of the spinal cord when turning to the position lying on the belly].
Topics: Adolescent; Age Factors; Analgesics; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Clonidine; Fentanyl; Hemodynamics; Humans; Ketamine; Kyphosis; Nitrous Oxide; Prone Position; Propofol; Respiration, Artificial; Scoliosis; Spinal Injuries; Spinal Neoplasms; Thiopental | 2005 |
Combined therapy with clonidine and amantadine may act in two stages of glutamate-mediated neuropathic pain caused by a needle puncture in an upper extremity.
Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Analgesics, Non-Narcotic; Calcium Channel Blockers; Catheterization, Peripheral; Clonidine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Ketamine; Median Nerve; Pain; Peripheral Nervous System Diseases; Receptors, N-Methyl-D-Aspartate | 2005 |
[Intrathecal injection of ketamine and clonidine for chronic neuropathic pain model in rats].
Topics: Analgesics; Animals; Clonidine; Drug Combinations; Injections, Spinal; Ketamine; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Spinal Cord | 2007 |
Topical analgesic combinations for bortezomib neuropathy.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Amines; Analgesics; Boronic Acids; Bortezomib; Clonidine; Cyclohexanecarboxylic Acids; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Ketamine; Male; Middle Aged; Pain Measurement; Paraproteinemias; Peripheral Nervous System Diseases; Protease Inhibitors; Pyrazines; Walking | 2009 |
Does analgesia and condition influence immunity after surgery? Effects of fentanyl, ketamine and clonidine on natural killer activity at different ages.
Topics: Age Factors; Analgesia; Animals; Clonidine; Fentanyl; Immunity, Cellular; Ketamine; Killer Cells, Natural; Male; Rats; Rats, Wistar; Risk Factors | 2010 |
Clonidine abolishes the adverse effects on apoptosis and behaviour after neonatal ketamine exposure in mice.
Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Environment; Female; Fluoresceins; Fluorescent Dyes; Ketamine; Male; Mice; Motor Activity; Organic Chemicals | 2012 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption | 2013 |
Influence of clonidine and ketamine on m-RNA expression in a model of opioid-induced hyperalgesia in mice.
Topics: Analgesics, Opioid; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Brain; Clonidine; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Ketamine; Male; Mice; Mice, Inbred C57BL; Morphine; Pain; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2013 |
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption | 2016 |
A Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine, DMSO) for Complex Regional Pain Syndrome Patients.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics; Anesthetics, Dissociative; Anti-Infective Agents, Local; Causalgia; Clonidine; Complex Regional Pain Syndromes; Dimethyl Sulfoxide; Female; Humans; Ketamine; Male; Middle Aged; Ointments; Pain Measurement; Pentoxifylline; Phosphodiesterase Inhibitors; Reflex Sympathetic Dystrophy; Treatment Outcome | 2016 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |
Toward Higher Sensitivity in Quantitative MALDI Imaging Mass Spectrometry of CNS Drugs Using a Nonpolar Matrix.
Topics: Animals; Brain Chemistry; Calibration; Central Nervous System Agents; Clonidine; Clozapine; Hydrophobic and Hydrophilic Interactions; Imipramine; Ketamine; Limit of Detection; Mice, Inbred C57BL; Nitriles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xylazine | 2018 |
Pain management in living related adult donor hepatectomy: feasibility of an evidence-based protocol in 100 consecutive donors.
Topics: Adult; Analgesia, Epidural; Anesthesia, Intravenous; Anesthetics; Clonidine; Evidence-Based Medicine; Female; Follow-Up Studies; Hepatectomy; Humans; Ketamine; Ketorolac; Laparotomy; Living Donors; Magnesium Sulfate; Male; Pain Management; Pain, Postoperative; Postoperative Period; Pregabalin; Premedication; Retrospective Studies | 2018 |
Effect of opioid-free anaesthesia on postoperative epidural ropivacaine requirement after thoracic surgery: A retrospective unmatched case-control study.
Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Case-Control Studies; Clonidine; Female; Humans; Injections, Intravenous; Ketamine; Lidocaine; Male; Middle Aged; Morphine; Pain, Postoperative; Retrospective Studies; Ropivacaine; Thoracic Surgical Procedures; Thoracotomy; Time Factors | 2019 |
Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Clonidine; Depressive Disorder, Treatment-Resistant; Female; Gyrus Cinguli; Hallucinogens; Humans; Infusions, Intravenous; Ketamine; Limbic System; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Psychiatric Status Rating Scales; Sympatholytics; Treatment Outcome; Young Adult | 2021 |
Anxiolytic-like effects of an mGluR 5 antagonist and a mGluR 2/3 agonist, and antidepressant-like effects of an mGluR 7 agonist in the chick social separation stress test, a dual-drug screening model of treatment-resistant depression.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Clonidine; Depression; Drug Evaluation, Preclinical; Exercise Test; Ketamine | 2023 |