clonidine and histamine

clonidine has been researched along with histamine in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	57 (67.86)	18.7374
1990's	16 (19.05)	18.2507
2000's	9 (10.71)	29.6817
2010's	1 (1.19)	24.3611
2020's	1 (1.19)	2.80

Authors

Authors	Studies
Botta, B; Botta, M; Carmignani, M; Corelli, F; De Bonnevaux, SC; De Luca, C; Delle Monache, F; Delle Monache, G; Espinal, R	1
Botta, B; Botta, M; Carmignani, M; Corelli, F; De Bonnevaux, SC; De Luca, C; Delle Monache, F; Espinal, R; Monache, GD; Ripanti, G; Tafi, A; Volpe, AR	1
Botta, B; Botta, M; Carmignani, M; Corelli, F; De Bonnevaux, SC; De Luca, C; Delle Monache, F; Delle Monache, G; Espinal, R; Vitali, A; Volpe, AR	1
Botta, B; Botta, M; Carmignani, M; Corelli, F; De Bonnevaux, SC; De Luca, C; Delle Monache, G; Espinal, R; Sacco, R; Tafi, A; Volpe, AR	1
Bednarczyk, D; Ekins, S; Wikel, JH; Wright, SH	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Greengard, P; Kanof, PD	1
McCulloch, MW; Medgett, IC	2
Greenberg, S; Palmer, GC	1
Bökesoy, TA; Ercan, ZS; Ersoy, F; Türker, RK; Zengil, H	1
Duckworth, JW; Lance, JW; Lord, GD; Mylecharane, EJ; Spira, PJ	1
Boer, PH; Fekkes, D; Korf, J	1
Audigier, Y; Schwartz, J; Virion, A	1
Fanchamps, A	1
Rivier, C; Vale, W	1
Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G	2
Phillis, JW; Sastry, BS	1
Huotari, R; Karppanen, H; Orma, AL; Paakkari, I; Paakkari, P	1
Fozard, JR	1
Kagaya, M; Miura, K; Miura, M; Miura, S; Onodera, A; Shioya, T; Yoshida, K	1
Cumming, P; Damsma, G; Fibiger, HC; Vincent, SR	1
Braun, SR; Chu, CS; Scott, GC	1
Fernandez-Alfonso, MS; Marín, J; Reviriego, J	1
Attramadal, H; Gordeladze, JO; Purvis, K; Rui, H	1
Holcslaw, TL; Lassiter, D	1
Houi, N; Itoh, T; Kamisaki, Y	1
Kitzen, JM; Lucchesi, BR; Söhngen, W; Ventura, A; Winbury, MM	1
Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC	1
Chen, HI; Kao, SJ; Shen, CY; Wang, D	1
Azuma, H; Ikenoue, Y; Ishikawa, M; Ito, S; Sugimoto-Tokushima, M; Tanaka, K	1
Li, CG; Rand, MJ	1
Advenier, C; Floch, A	1
Carrier, GO; White, RE	1
Livingston, A; Nolan, A; Waterman, A	1
Clerici, C; Harf, A; Macquin-Mavier, I	1
Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J; Vitou, P	1
Leff, P; Trist, DG	1
Livett, BG; Marley, PD; Powis, DA; Wan, DC	1
Advenier, C; Dinh Xuan, AT; Lockhart, A; Mantrand, P; Matran, R; Regnard, J	1
Kulkarni, SK; Kunchandy, J; Mehta, AK	1
Andersson, RG; Brundin, A; Lindgren, BR	1
Anderson, CD; Andersson, RG; Lindgren, BR	1
Andersson, RG; Ekström, T; Lindgren, BR	1
Junnarkar, AY; Shridhar, DR; Singh, PP	1
Csongrady, A; Kobinger, W	1
Karppanen, HO; Westermann, E	1
Anthony, M; Lance, JW	1
Hodge, RL; Robinson, SM	1
Curwain, BP; Endersby, K	1
Fuller, LM	1
De Moraes, S; Rae, GA	1
Agnoli, A; Ceci, E; Denaro, A; Falaschi, P	1
Robinson, BV	1
Genton, M; Pascaud, X; Roger, A; Rozé, C	1
Balsara, JJ; Chandorkar, AG; Jadhav, JH	1
Bugajski, J; Gadek, A	1
Chaudhry, A; Vohra, MM	1
Bernardini, C; Del Tacca, M; Impicciatore, M; Martinotti, E; Soldani, G	2
Holsapple, MP; Lowy, MT; Malave, A; Yim, GK	1
Duckworth, JW; Lance, JW; Lord, GD; Mylecharane, EJ	1
Berlan, M; Carpene, C; Dang Tran, L; Lafontan, M	1
Angus, JA; Kenakin, TP	1
Sanchez-Chapula, J	1
McCulloch, MW; Medgett, IC; Rand, MJ; Story, DF	1
Arrigo-Reina, R; Chiechio, S	1
Brown, CM; Hussain, JF; Kendall, DA; MacKinnon, A; Singh, G; Wilson, VG	1
Spencer, DM; Wilkin, JK	1
Guidobono, F; Netti, C; Pecile, A; Sibilia, V	1
Borycz, J; Bugajski, J; Gadek-Michalska, A	1
Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A	1
Borycz, J; Bugajski, J; Gadek-Michalska, A; Głód, R; Ołowska, A	1
Horie, S; Watanabe, K; Yamamoto, LT; Yano, S	1
el-Sherbeeny, M; Khayyal, MA; Khayyal, MT; Okpanyi, SN; Schneider, W; Sharaf, HM	1
Kyselá, S; Török, J	1
Calhau, C; Gründemann, D; Martel, F; Schömig, E	1
Bose, D; Cheng, ZQ; Jacobs, H; Light, RB; Mink, SN	1
Gil Marqués, M; Martínez-Mir, I; Morales-Olivas, FJ; Rubio-Gomis, E	1
Fort, P; Frydman, A; Gallopin, T; Luppi, PH; Rambert, FA	1
Danyali, F; Ebrahimi-Ghiri, M; Oryan, S; Torkaman-Boutorabi, A; Zarrindast, MR	1
Borgonetti, V; Galeotti, N; Masini, E; Sanna, MD	1

Reviews

3 review(s) available for clonidine and histamine

Article	Year
[Classification, pathogenesis and drug therapy of migraine and related forms of headache]. Die Medizinische Welt, 1975, Aug-29, Volume: 6, Issue:35 Topics: Adrenergic beta-Antagonists; Animals; Caffeine; Clonidine; Dihydroergotamine; Drug Synergism; Epinephrine; Ergotamine; Headache; Histamine; Humans; Methysergide; Mice; Migraine Disorders; Norepinephrine; Pizotyline; Serotonin	1975
Current concepts in the pathogenesis and interval treatment of migraine. Drugs, 1972, Volume: 3, Issue:3 Topics: Adrenergic beta-Antagonists; Bradykinin; Clonidine; Cycloheptanes; Cyproheptadine; Ergotamine; Histamine; Humans; Methysergide; Migraine Disorders; Norepinephrine; Piperidines; Prostaglandins; Serotonin; Serotonin Antagonists; Thiophenes; Tyramine	1972
The pharmacology of drinking behavior. Pharmacology & therapeutics, 1984, Volume: 24, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Clonidine; Diuretics; Dopamine; Drinking; Drinking Behavior; gamma-Aminobutyric Acid; Histamine; Hormones; Humans; Lithium; Narcotics; Norepinephrine; Parasympathetic Nervous System; Pepstatins; Prostaglandins; Receptors, Adrenergic; Renin-Angiotensin System; Saralasin; Serotonin; Vasopressins	1984

Trials

5 trial(s) available for clonidine and histamine

Article	Year
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1975, Sep-19, Volume: 117, Issue:38 Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, Combination; Ergotamine; Headache; Histamine; Humans; Indomethacin; Metergoline; Methysergide; Migraine Disorders; Pizotyline; Prochlorperazine; Reserpine; Retrospective Studies; Urea	1975
Transdermal delivery of the alpha 2-agonist clonidine does not alter airways responses to inhaled histamine or methacholine. Chest, 1991, Volume: 100, Issue:4 Topics: Administration, Cutaneous; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Clonidine; Double-Blind Method; Histamine; Humans; Methacholine Chloride	1991
Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. British journal of clinical pharmacology, 1988, Volume: 26, Issue:6 Topics: Adrenergic alpha-Agonists; Adult; Asthma; Bronchi; Clonidine; Female; Forced Expiratory Volume; Histamine; Humans; Male; Oxazoles; Rilmenidine	1988
Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects. The European respiratory journal, 1988, Volume: 1, Issue:4 Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Humans; Male; Premedication	1988
Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma. The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:6 Topics: Allergens; Asthma; Clonidine; Histamine; Humans; Hydrocortisone; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Intradermal Tests; Skin Tests	1987

Other Studies

76 other study(ies) available for clonidine and histamine

Article	Year
Novel hypotensive agents from Verbesina caracasana. 2. Synthesis and pharmacology of caracasanamide. Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20 Topics: Acylation; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Cinnamates; Guanidines; Heart Rate; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Structure; Myocardial Contraction; Plant Extracts; Receptors, Adrenergic, beta; Respiration; Stimulation, Chemical; Vasodilation	1993
Novel hypotensive agents from Verbesina caracasana. 6. Synthesis and pharmacology of caracasandiamide. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclobutanes; Guanidines; Heart Rate; Hydrolysis; Injections, Intravenous; Male; Plant Extracts; Rats; Rats, Wistar; Respiratory Mechanics; Spectrometry, Mass, Fast Atom Bombardment; Stroke Volume; Tidal Volume; Ventricular Pressure	1999
Further hypotensive metabolites from Verbesina caracasana. Bioorganic & medicinal chemistry letters, 1999, Nov-15, Volume: 9, Issue:22 Topics: Animals; Antihypertensive Agents; Asteraceae; Mass Spectrometry; Rats	1999
Novel hypotensive agents from Verbesina caracasana. 8. Synthesis and pharmacology of (3,4-dimethoxycinnamoyl)-N(1)-agmatine and synthetic analogues. Journal of medicinal chemistry, 2001, Aug-30, Volume: 44, Issue:18 Topics: Agmatine; Animals; Antihypertensive Agents; Blood Pressure; Guanidines; Heart Rate; Male; Plants, Medicinal; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Venezuela	2001
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1. Molecular pharmacology, 2003, Volume: 63, Issue:3 Topics: Computational Biology; HeLa Cells; Humans; Models, Molecular; Organic Cation Transporter 1; Pyridinium Compounds; Quinolinium Compounds; Structure-Activity Relationship; Transfection	2003
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Pharmacological properties of histamine-sensitive adenylate cyclase from guinea pig cardiac ventricular muscle. Molecular pharmacology, 1979, Volume: 15, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Clonidine; Enzyme Activation; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine N-Methyltransferase; In Vitro Techniques; Male; Myocardium; Receptors, Histamine H1; Receptors, Histamine H2	1979
Effects of clonidine, guanfacine and three imidazolidine derivatives related to clonidine on blood pressure, heart rate and gastric acid secretion in the anaesthetized rat. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:1 Topics: Animals; Antihypertensive Agents; Blood Pressure; Cimetidine; Clonidine; Female; Gastric Juice; Guanidines; Heart Rate; Histamine; Hydrogen-Ion Concentration; Imidazoles; Male; Phenylacetates; Rats	1979
Alterations in myocardial adenylate cyclase in spontaneously hypertensive rats. Pharmacology, 1979, Volume: 19, Issue:3 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Catecholamines; Clonidine; Glucagon; Guanylyl Imidodiphosphate; Histamine; Hypertension; Male; Myocardium; Propranolol; Rats	1979
Possible involvement of endogenous histamine in the myotropic effect of clonidine on the isolated rabbit aorta. Agents and actions, 1978, Volume: 8, Issue:5 Topics: Amine Oxidase (Copper-Containing); Animals; Aorta, Thoracic; Blood Vessels; Clonidine; Female; Histamine; Histidine Decarboxylase; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Pyrilamine; Rabbits	1978
Evaluation of drugs applicable to treatment of migraine in the cranial circulation of the monkey. Research and clinical studies in headache, 1978, Volume: 6 Topics: Acetylcholine; Animals; Bradykinin; Cerebrovascular Circulation; Cimetidine; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Ergotamine; Haplorhini; Histamine; Macaca; Methysergide; Metiamide; Migraine Disorders; Norepinephrine; Pizotyline; Prostaglandins; Serotonin	1978
CYCLIC AMP/SECRETl cyclic AMP into push-pull perfusates in freely moving rats. Brain research, 1976, Sep-03, Volume: 113, Issue:3* Topics: Adenosine; Animals; Brain; Cerebral Ventricles; Clonidine; Cyclic AMP; Dopamine; Histamine; Isoproterenol; Levodopa; Male; Norepinephrine; Perfusion; Rats; Receptors, Adrenergic; Serotonin	1976
Stimulation of cerebral histamine H2 receptors by clonidine. Nature, 1976, Jul-22, Volume: 262, Issue:5566 Topics: Animals; Clonidine; Cyclic AMP; Guinea Pigs; Hippocampus; Histamine; Male; Receptors, Drug	1976
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat. Endocrinology, 1977, Volume: 101, Issue:2 Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone	1977
Evidence that clonidine can activate histamine H2-receptors in rat cerebral cortex. Neuropharmacology, 1977, Volume: 16, Issue:3 Topics: Action Potentials; Animals; Cerebral Cortex; Clonidine; Histamine; Histamine Antagonists; Male; Metiamide; Norepinephrine; Rats; Receptors, Histamine; Receptors, Histamine H2	1977
[Therapeutic possibilities in idiopathic headaches. Analysis of about 1000 cases]. Minerva medica, 1976, Jun-23, Volume: 67, Issue:31 Topics: Cinnarizine; Clonidine; Cyproheptadine; Headache; Histamine; Humans; Methysergide; Migraine Disorders; Monoamine Oxidase Inhibitors; Peptides; Pizotyline; Reserpine; Urea; Vascular Headaches	1976
Possible involvement of central histamine H2-receptors in the hypotensive effect of clonidine. Nature, 1976, Feb-19, Volume: 259, Issue:5544 Topics: Blood Pressure; Brain; Clonidine; Histamine; Metiamide; Receptors, Drug	1976
Comparative effects of four migraine prophylactic drugs on an isolated extracranial artery. European journal of pharmacology, 1976, Volume: 36, Issue:1 Topics: Animals; Carotid Artery, External; Chlorides; Clonidine; Cyproheptadine; Drug Interactions; Histamine; Methysergide; Norepinephrine; Phentolamine; Pizotyline; Potassium; Pyrilamine; Rabbits; Serotonin; Thiophenes; Tryptamines; Tyramine; Vasoconstrictor Agents	1976
[Measurement of isometric tracheal tension induced by injection into tracheal arterial circulation in vivo]. Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:12 Topics: Acetylcholine; Animals; Arteries; Clonidine; Dogs; Dose-Response Relationship, Drug; Histamine; Injections, Intra-Arterial; Muscle Contraction; Muscle, Smooth; Phenylephrine; Receptors, Adrenergic, beta; Regional Blood Flow; Serotonin; Thyroid Gland; Trachea	1991
Characterization of extracellular histamine in the striatum and bed nucleus of the stria terminalis of the rat: an in vivo microdialysis study. Journal of neurochemistry, 1991, Volume: 56, Issue:5 Topics: Animals; Clonidine; Corpus Striatum; Dialysis; Extracellular Space; Histamine; Histamine Release; Male; Methylhistidines; Rats; Rats, Inbred Strains; Tetrodotoxin; Thalamic Nuclei; Yohimbine	1991
Actions of vasoactive drugs on human placental vascular smooth muscle. General pharmacology, 1990, Volume: 21, Issue:5 Topics: Arteries; Clonidine; Diphenhydramine; Dopamine; Female; Histamine; Humans; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Placenta; Pregnancy; Regional Blood Flow; Serotonin; Veins	1990
Hormonal activation of the adenylyl cyclases of the rat and human prostate gland. The Prostate, 1986, Volume: 8, Issue:1 Topics: Adenylyl Cyclases; Alprostadil; Animals; Clonidine; Dopamine; Enzyme Activation; Histamine; Humans; Isoproterenol; Male; Orchiectomy; Propanolamines; Prostate; Prostatic Hyperplasia; Rats; Rats, Inbred Strains; Seminal Vesicles; Terbutaline; Vasoactive Intestinal Peptide	1986
Evidence for presynaptic inhibitory histamine (H2) receptors in the rat hindquarter vasculature. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:6 Topics: Animals; Blood Vessels; Cimetidine; Clonidine; Electric Stimulation; Hindlimb; Histamine; Imidazoles; Impromidine; Male; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Neurotransmitter; Sympathetic Nervous System; Vasodilation	1987
Effects of histamine H2 receptor antagonists on acid secretion stimulated by imidazoline derivatives in isolated parietal cells. European journal of pharmacology, 1987, Nov-24, Volume: 144, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Clonidine; Cyclic AMP; Drug Interactions; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Male	1987
The mechanism for the clonidine-induced coronary artery dilatation in the canine heart. Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:6 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Antihypertensive Agents; Blood Platelets; Blood Pressure; Cimetidine; Clonidine; Coronary Circulation; Coronary Vessels; Dogs; Histamine; In Vitro Techniques; Male; Perfusion; Receptors, Purinergic; Serotonin; Vasodilator Agents	1988
Modulation of histamine release and synthesis in the brain mediated by alpha 2-adrenoceptors. Journal of neurochemistry, 1989, Volume: 53, Issue:2 Topics: Animals; Brain; Clonidine; Histamine; Histamine Antagonists; In Vitro Techniques; Norepinephrine; Potassium; Rats; Receptors, Adrenergic, alpha; Yohimbine	1989
The effects of alpha 2-adrenergic agonism with clonidine on the pulmonary and collateral resistances in the canine lung challenged with histamine. The Chinese journal of physiology, 1989, Volume: 32, Issue:1 Topics: Airway Resistance; Animals; Clonidine; Dogs; Histamine; Isoproterenol; Lung; Male; Receptors, Adrenergic, alpha; Yohimbine	1989
Alpha 1-adrenoceptor antagonist activity of novel pyrimidine derivatives (SHI437 and IK29) in rabbit aorta and trigone of the bladder. British journal of pharmacology, 1989, Volume: 96, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Dinoprost; Electric Stimulation; Histamine; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Piperazines; Potassium Chloride; Pyrimidines; Rabbits; Serotonin; Urinary Bladder; Vas Deferens	1989
Rilmenidine differs from clonidine in that it lacks histamine-like activity. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:7 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Guinea Pigs; Heart; Heart Rate; Histamine; In Vitro Techniques; Male; Myocardium; Oxazoles; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Rilmenidine; Uterine Contraction; Uterus	1989
Interaction between clonidine and histamine on the guinea-pig isolated trachea. The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:12 Topics: Animals; Clonidine; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Trachea	1985
Alpha 1- and alpha 2-adrenoceptor agonist-induced contraction in rat mesenteric artery upon removal of endothelium. European journal of pharmacology, 1986, Apr-02, Volume: 122, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Endothelium; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains	1986
The effects of alpha 2 adrenoceptor agonists on airway pressure in anaesthetized sheep. Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Airway Resistance; Animals; Clonidine; Dioxanes; Female; Histamine; Idazoxan; Injections, Intravenous; Injections, Intraventricular; Methoxamine; Prazosin; Pyrilamine; Sheep; Tripelennamine; Xylazine	1986
Effects of rilmenidine on bronchomotor responses in the guinea pig. The American journal of cardiology, 1988, Feb-24, Volume: 61, Issue:7 Topics: Adrenergic alpha-Agonists; Animals; Bronchi; Clonidine; Compliance; Drug Synergism; Guinea Pigs; Histamine; Male; Oxazoles; Rilmenidine	1988
Quantification of H2-agonism by clonidine and dimaprit in an adenylate cyclase assay. Agents and actions, 1985, Volume: 16, Issue:3-4 Topics: Adenylyl Cyclases; Animals; Cimetidine; Clonidine; Dimaprit; Guinea Pigs; Histamine; In Vitro Techniques; Myocardium; Receptors, Histamine; Receptors, Histamine H2; Thiourea	1985
Effects of alpha- and beta-adrenoceptor agonists and antagonists on ATP and catecholamine release and desensitization of the nicotinic response in bovine adrenal chromaffin cells. Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4 Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Catecholamines; Cattle; Cell Membrane; Chromaffin System; Clonidine; Histamine; In Vitro Techniques; Nicotine; Potassium; Propranolol; Receptors, Adrenergic; Sodium	1988
Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Azepines; Bradykinin; Carrageenan; Clonidine; Edema; Formaldehyde; Guanfacine; Guanidines; Histamine; Injections, Intraventricular; Male; Phenylacetates; Rats; Rats, Inbred Strains; Serotonin; Time Factors	1986
Effects of clonidine on the dermal inflammatory cell response of experimental toxic and allergic contact reactions and intradermal hypersensitivity. International archives of allergy and applied immunology, 1987, Volume: 83, Issue:4 Topics: Animals; Cell Movement; Clonidine; Croton Oil; Dermatitis, Contact; Drug Hypersensitivity; Female; Granulocytes; Guinea Pigs; Histamine; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Mast Cells; Ovalbumin; Oxazolone; Skin; Skin Tests	1987
The effect of inhaled clonidine in patients with asthma. The American review of respiratory disease, 1986, Volume: 134, Issue:2 Topics: Administration, Intranasal; Adolescent; Adult; Asthma; Clonidine; Eosinophils; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; Respiration	1986
Possible involvement of central adrenergic and histaminergic systems in clonidine-induced inhibition of pinna reflex. Pharmacological research communications, 1985, Volume: 17, Issue:3 Topics: Animals; Biogenic Amines; Brain Chemistry; Clonidine; Ear, External; Female; Histamine; Male; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System	1985
Investigations into the positive inotropic effect of clondine in isolated hearts. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:2 Topics: Action Potentials; Animals; Clonidine; Dose-Response Relationship, Drug; Electrocardiography; Female; Guinea Pigs; Heart; Heart Rate; Histamine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Perfusion; Pheniramine; Phentolamine; Phenyl Ethers; Propanolamines; Propylamines; Receptors, Drug; Stimulation, Chemical; Thiourea	1974
Increased production of cyclic AMP in gastric tissue by stimulation of histamine2 (H2)-receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:1 Topics: Animals; Binding, Competitive; Clonidine; Cyclic AMP; Diphenhydramine; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Rats; Receptors, Drug; Theophylline; Thiourea	1973
The action of clonidine on isolated arterial preparations. The Australian journal of experimental biology and medical science, 1972, Volume: 50, Issue:4 Topics: Animals; Arteries; Clonidine; Cocaine; Constriction; Ear, External; Histamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Perfusion; Phentolamine; Rabbits; Rats; Receptors, Adrenergic; Sympathectomy; Tail	1972
Enhancement of pentagastrin-induced gastric acid secretion by clonidine in the conscious dog. British journal of pharmacology, 1974, Volume: 50, Issue:3 Topics: Animals; Blood Flow Velocity; Clonidine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Gastric Juice; Histamine; Pentagastrin; Stomach; Tritium	1974
Presynaptic alpha 2-adrenoceptor subsensitivity in the morphine-withdrawn mouse vas deferens. European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4 Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Male; Mice; Morphine; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome; Vas Deferens	1984
Receptor sites of action of clonidine: effects of clonidine and three structural isomers on prejunctional and postjunctional alpha-adrenoceptors and histamine H2-receptors in guinea-pig isolated cardiovascular tissues. The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:2 Topics: Animals; Blood Pressure; Cardiovascular System; Clonidine; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Isomerism; Muscle, Smooth, Vascular; Neuromuscular Junction; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Histamine H2	1980
On the etiopathogenesis of migraine: a possible link between the amines and endorphin hypotheses. Advances in neurology, 1982, Volume: 33 Topics: Adult; Clonidine; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Histamine; Humans; Male; Middle Aged; Migraine Disorders; Neurotransmitter Agents; Norepinephrine; Pain; Premedication; Prolactin; Sensory Thresholds; Serotonin; Substance Withdrawal Syndrome	1982
Histamine receptor agonists and antagonists on granulocyte adherence. The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:7 Topics: Cimetidine; Clonidine; Granulocytes; Histamine; Histamine Antagonists; Humans; Pyrilamine	1982
Further support for the central origin of the gastric antisecretory properties of clonidine in conscious rats. European journal of pharmacology, 1982, Dec-24, Volume: 86, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Deoxyglucose; Depression, Chemical; Drug Interactions; Gastric Mucosa; Histamine; Male; Methacholine Chloride; Methacholine Compounds; Pentagastrin; Rats; Rats, Inbred Strains	1982
Involvement of histaminergic mechanisms in the cataleptogenic effect of clonidine in mice. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:10 Topics: Animals; Apomorphine; Catalepsy; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histidine; Humans; Mice; Phenoxybenzamine; Stereotyped Behavior; Yohimbine	1983
Interference of clonidine and alpha-methyl-p-tyrosine with stress and central histaminergic stimulation of the corticosterone response in rats. Agents and actions, 1984, Volume: 14, Issue:3-4 Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Brain; Clonidine; Corticosterone; Histamine; Immobilization; Male; Methyltyrosines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Stress, Physiological	1984
Antagonism by the tetramine disulfide benextramine of the inhibitory effects mediated by prejunctional alpha 2-adrenoceptors and by postjunctional histamine H2 receptors in the mouse vas deferens. Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:9 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cystamine; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Male; Mice; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Histamine H2; Vas Deferens	1984
Evidence for two opposite effects of clonidine on gastric acid secretion in the dog. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 327, Issue:2 Topics: Animals; Bethanechol Compounds; Clonidine; Dogs; Gastric Acid; Histamine; Pentagastrin; Yohimbine	1984
Central and peripheral anti-inflammatory actions by clonidine and a structurally related imidazoline analog. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:2 Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Brain; Carrageenan; Clonidine; Edema; Histamine; Male; Prostaglandins; Rats; Rats, Inbred Strains; Serotonin	1984
Pharmacological studies on the mechanisms underlying the inhibitory and excitatory effects of clonidine on gastric acid secretion. European journal of pharmacology, 1982, Jul-09, Volume: 81, Issue:2 Topics: Acetylcholine; Animals; Clonidine; Female; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains; Stomach	1982
Effects of low doses of clonidine in the monkey cranial circulation. European journal of pharmacology, 1980, Nov-21, Volume: 68, Issue:2 Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Clonidine; Dose-Response Relationship, Drug; Histamine; Macaca nemestrina; Migraine Disorders; Norepinephrine; Sympathetic Nervous System; Vascular Resistance	1980
Clonidine-induced lipolysis in dog adipocytes by stimulation of histamine (H2)-receptors. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 249, Issue:2 Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Clonidine; Dogs; Histamine; Lipolysis; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Theophylline	1981
The histamine-like effects of tolazoline and clonidine:: evidence against direct activity at histamine receptors. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:2 Topics: Animals; Clonidine; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Histamine; Tolazoline	1981
Differential effects of histamine on left and righ guinea-pig atria. European journal of pharmacology, 1981, Sep-11, Volume: 74, Issue:2-3 Topics: Action Potentials; Animals; Cimetidine; Clonidine; Dose-Response Relationship, Drug; Functional Laterality; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Myocardial Contraction	1981
Structure-activity relationship of imidazolidine derivatives related to clonidine at histamine H2-receptors in guinea-pig isolated atria. British journal of pharmacology, 1980, Volume: 69, Issue:3 Topics: Animals; Clonidine; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; In Vitro Techniques; Male; Oxymetazoline; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Structure-Activity Relationship	1980
Histaminergic mechanisms in clonidine induced analgesia in rat tail-flick test. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:1 Topics: Analgesics; Animals; Clonidine; Cold Temperature; Histamine; Histidine Decarboxylase; Male; Methylhistidines; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Restraint, Physical; Stress, Psychological; Yohimbine	1995
Evidence for the presence of a non-catecholamine, clonidine-displacing substance in crude, methanolic extracts of bovine brain and lung. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:1 Topics: Animals; Binding, Competitive; Biological Factors; Brain Chemistry; Catecholamines; Cations, Monovalent; Cattle; Chromatography, Liquid; Clonidine; Histamine; In Vitro Techniques; Lung; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley	1995
Parmesan cheese and vegetable-induced histaminuria in a thermal flusher. Cutis, 1994, Volume: 54, Issue:3 Topics: Cheese; Clonidine; Exercise; Female; Flushing; Histamine; Humans; Middle Aged; Vegetables	1994
Influence of brain histamine on growth hormone secretion induced by alpha-2-receptor activation. Neuroendocrinology, 1993, Volume: 57, Issue:6 Topics: Animals; Brain Chemistry; Clonidine; Cysteamine; Growth Hormone; Histamine; Injections, Intraventricular; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Somatostatin	1993
Social crowding stress diminishes the pituitary-adrenocortical and hypothalamic histamine response to adrenergic stimulation. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:4 Topics: Animals; Clonidine; Corticosterone; Crowding; Histamine; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Isoproterenol; Male; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Stress, Psychological; Sympathetic Nervous System; Sympathomimetics	1993
Central histaminergic mechanisms in the corticosterone response to clonidine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:3 Topics: Animals; Brain; Clonidine; Corticosterone; Histamine; Histamine Antagonists; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Methylhistidines; Pituitary-Adrenal System; Rats; Rats, Wistar; Yohimbine	1993
The role of prostaglandins and the hypothalamic and hippocampal histamine in the clonidine-induced pituitary-adrenocortical response. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Corticosterone; Hippocampus; Histamine; Hypothalamus; Indomethacin; Male; Pituitary-Adrenal System; Prostaglandins; Rats; Rats, Wistar	1996
Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor. Life sciences, 1997, Volume: 60, Issue:12 Topics: Acetylcholine; Analgesics; Animals; Clonidine; Diterpene Alkaloids; Electric Stimulation; Guinea Pigs; Histamine; Ileum; Male; Morphine; Muscle Contraction; Naloxone; Neurotransmitter Agents; Nicardipine; Receptors, Opioid; Secologanin Tryptamine Alkaloids; Substance Withdrawal Syndrome	1997
Effect of magnesium pyridoxal 5-phosphate glutamate on vascular reactivity in experimental hypercholesterolemia. Drugs under experimental and clinical research, 1998, Volume: 24, Issue:1 Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Cholesterol, Dietary; Clonidine; Drug Evaluation, Preclinical; Glutamine; Histamine; Hypercholesterolemia; Hypolipidemic Agents; In Vitro Techniques; Male; Norepinephrine; Pyridoxal Phosphate; Rabbits; Vasoconstrictor Agents; Vasomotor System	1998
Contemporary activation of different endothelial receptors accounts for a reserve mechanism of nitric oxide-mediated relaxation. Physiological research, 2000, Volume: 49, Issue:1 Topics: Acetylcholine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Endothelium, Vascular; Histamine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Histamine; Receptors, Muscarinic; Receptors, Purinergic; Vasodilator Agents	2000
Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1 Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Caco-2 Cells; Carrier Proteins; Cations; Cell Line; Clonidine; Corticosterone; DNA, Recombinant; Dose-Response Relationship, Drug; Gene Expression; Histamine; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Membrane Potentials; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Plasmids; Quinolines; Quinolinium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Time Factors; Transfection; Tritium	2001
Sepsis causes presynaptic histamine H3 and alpha2-adrenergic dysfunction in canine myocardium. Cardiovascular research, 2002, Volume: 56, Issue:2 Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Culture Techniques; Dogs; GTP-Binding Proteins; Heart; Histamine; Myocardial Contraction; Pertussis Toxin; Receptors, Adrenergic, alpha-2; Receptors, Histamine H3; Shock, Septic; Sympathetic Nervous System; Yohimbine	2002
Characteristics of histamine tachyphylaxis in rat uterine smooth muscle. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:12 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Epinephrine; Estrogens; Female; Histamine; Histamine Agonists; In Vitro Techniques; Isotonic Contraction; Muscle Relaxation; Rats; Rats, Wistar; Tachyphylaxis; Uterine Contraction; Uterus	2002
Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study. Sleep, 2004, Feb-01, Volume: 27, Issue:1 Topics: Animals; Benzhydryl Compounds; Carbachol; Cholinergic Agonists; Clonidine; Electrophysiology; Fluoxetine; Histamine; In Vitro Techniques; Modafinil; Neurons; Neuroprotective Agents; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sleep; Sympathomimetics; Visual Pathways; Wakefulness	2004
Hippocampal α-adrenoceptors involve in the effect of histamine on spatial learning. Physiology & behavior, 2014, Apr-22, Volume: 129 Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; CA1 Region, Hippocampal; Clonidine; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Male; Maze Learning; Phenylephrine; Prazosin; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Task Performance and Analysis; Yohimbine	2014
Histamine H European journal of pharmacology, 2020, Feb-05, Volume: 868 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzimidazoles; Clonidine; Disease Models, Animal; Guanidines; Histamine; Humans; Injections, Spinal; Locus Coeruleus; Male; Mice; Mice, Knockout; Microinjections; Neuralgia; Norepinephrine; Pain Management; Receptors, Histamine H4; Thiourea	2020