Compounds > clonidine

clonidine and hexobarbital

clonidine has been researched along with hexobarbital in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
de Jonge, A; Jonkman, FA; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Van Zwieten, PA1
Kobinger, W; Pichler, L1
Beckeringh, JJ; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Ali, FK; Kwa, HY; Timmermans, PB; van Zwieten, PA1
de Jonge, A; Timmermans, PB; van Zwieten, PA1
Iizuka, H; Imai, S1

Other Studies

11 other study(ies) available for clonidine and hexobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; Decerebrate State; Female; Heart Rate; Hexobarbital; In Vitro Techniques; Male; Mice; Oxazoles; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rilmenidine; Sleep; Time Factors

1986
Pharmacology of the alpha 2-adrenoceptor agonist rilmenidine.
    The American journal of cardiology, 1988, Feb-24, Volume: 61, Issue:7

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Central Nervous System; Chemical Phenomena; Chemistry; Clonidine; Dose-Response Relationship, Drug; Hexobarbital; Humans; Hypnotics and Sedatives; Mice; Oxazoles; Rats; Rilmenidine; Sleep

1988
Possible function of alpha 1-adrenoceptors in the CNS in anaesthetized and conscious animals.
    European journal of pharmacology, 1985, Jan-08, Volume: 107, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Brain; Catalepsy; Cats; Clonidine; Dogs; Exploratory Behavior; Female; Haloperidol; Heart Rate; Hexobarbital; Humans; Male; Mice; Mice, Inbred Strains; Pressoreceptors; Receptors, Adrenergic, alpha; Reflex; Sleep

1985
Cardiovascular effects and interaction with adrenoceptors of urapidil.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 276, Issue:2

    Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cats; Clonidine; Decerebrate State; Female; Hemodynamics; Hexobarbital; In Vitro Techniques; Infusions, Parenteral; Male; Membranes; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Piperazines; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic

1985
Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 245, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Clonidine; Doxazosin; Heart Rate; Hemodynamics; Hexobarbital; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Quinazolines; Rats

1980
Hypotensive and alpha-adrenergic activities of 2-(2,3,6-trichlorophenylimino) and 2-(2,3-dichloro-6-methylphenylimino) imidazolidine, two potent derivatives of clonidine.
    British journal of pharmacology, 1983, Volume: 78, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hexobarbital; Hypnotics and Sedatives; Imidazolidines; Male; Mice; Prazosin; Rats; Rats, Inbred Strains; Sleep; Structure-Activity Relationship

1983
[Effects of guanfacine on the central nervous system (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:7

    Topics: Analgesics; Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Brain; Clonidine; Drug Synergism; Electroencephalography; Guanfacine; Guanidines; Hexobarbital; Male; Mice; Phenylacetates; Rats; Rectum; Sleep

1980