clonidine has been researched along with enkephalin, leucine-2-alanine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garzón, J; Sánchez-Blázquez, P | 1 |
| Amerini, S; Ledda, F; Mantelli, L | 1 |
| Mulder, AH; Schoffelmeer, AN; Wierenga, EA | 1 |
| Beitner, DB; Duman, RS; Nestler, EJ | 1 |
| Stevens, CW; Yaksh, TL | 1 |
| Chuang, DM; Zhu, XZ | 1 |
| Geppert, M; Illes, P; Jackisch, R | 1 |
| Keith, RA; Salama, AI | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; McWilliam, JR | 2 |
| Berry-Kravis, E; Dawson, G | 2 |
| Aghajanian, GK; Freedman, JE | 1 |
| Gershow, J; Krames, ES; Wilkie, DJ | 1 |
| Mulder, AH; Putters, J; Schoffelmeer, AN | 1 |
| Coombs, DW; Jensen, LE; Lachance, D; Ragnarsson, TS; Saunders, RL; Savage, S | 1 |
| Dawson, G; Louie, AK | 1 |
| Ammer, H; Schulz, R | 1 |
| Gyires, K; Müllner, K; Rónai, AZ | 1 |
| Barna, I; Gyires, K; Müllner, K; Palkovits, M; Reichart, A; Rónai, AZ | 1 |
20 other study(ies) available for clonidine and enkephalin, leucine-2-alanine
| Article | Year |
|---|---|
Cholera toxin and pertussis toxin on opioid- and alpha 2-mediated supraspinal analgesia in mice.
Topics: Analgesia; Animals; beta-Endorphin; Cerebral Ventricles; Cholera Toxin; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Morphine; Narcotics; Pain; Pertussis Toxin; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1991 |
Opioid agonists, prostaglandin E1 and clonidine modulate non-adrenergic, non-cholinergic transmission in the mammalian heart.
Topics: Adrenergic beta-Antagonists; Alprostadil; Animals; Atrial Function; Capsaicin; Clonidine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Morphine; Myocardial Contraction; Nerve Fibers | 1990 |
Role of adenylate cyclase in presynaptic alpha 2-adrenoceptor- and mu-opioid receptor-mediated inhibition of [3H]noradrenaline release from rat brain cortex slices.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Bucladesine; Cadmium; Calcimycin; Cerebral Cortex; Clonidine; Colforsin; Cyclic AMP; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Norepinephrine; Phentolamine; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu; Rolipram | 1986 |
A novel action of morphine in the rat locus coeruleus: persistent decrease in adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Locus Coeruleus; Male; Morphine; Naloxone; Opioid-Related Disorders; Rats; Rats, Inbred Strains | 1989 |
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
Topics: Analgesics; Animals; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Infusions, Parenteral; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Reference Values; Sufentanil | 1989 |
Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells.
Topics: Alprostadil; Animals; Binding, Competitive; Brain; Bucladesine; Butyrates; Butyric Acid; Carbachol; Clonidine; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Opioid; Receptors, Opioid, delta; Tumor Cells, Cultured | 1988 |
Characterization of opioid receptors modulating noradrenaline release in the hippocampus of the rabbit.
Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hippocampus; Morphine; Norepinephrine; Rabbits; Receptors, Opioid | 1986 |
Inhibition of presynaptic alpha-2-adrenoceptor and opioid receptor agonist responses in the rat vas deferens by chronic imipramine treatment.
Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Imipramine; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Parasympathomimetics; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Vas Deferens | 1987 |
Synaptosomal free [Ca2+] is reduced by clonidine and dynorphin A-(1-13) and increased by idazoxan.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Calcium; Clonidine; Dioxanes; Dioxins; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Idazoxan; In Vitro Techniques; Male; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
Mutual antagonism of kappa-opiate and alpha 2-adrenoceptor agonist effects on intrasynaptosomal free [Ca2+]i.
Topics: Aminoquinolines; Animals; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fluorescent Dyes; Idazoxan; Male; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Synaptosomes | 1988 |
Evidence for [D-Ala2,D-Leu5]enkephalin-induced supersensitivity to 5-hydroxytryptamine in a neurotumor x brain hybrid cell line (NCB-20).
Topics: Adenylyl Cyclases; Alprostadil; Animals; Brain; Brain Chemistry; Cell Line; Cholera Toxin; Clonidine; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Mice; Neuroblastoma; Receptors, Serotonin; Serotonin | 1985 |
Opiate and alpha 2-adrenoceptor responses of rat amygdaloid neurons: co-localization and interactions during withdrawal.
Topics: Amygdala; Animals; Clonidine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Iontophoresis; Male; Microelectrodes; Morphine; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1985 |
Intrathecal D-Ala2-D-Leu5-enkephalin (DADL) restores analgesia in a patient analgetically tolerant to intrathecal morphine sulfate.
Topics: Aged; Carcinoma; Clonidine; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Injections, Spinal; Male; Morphine; Naloxone; Pain, Intractable; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Skull Neoplasms; Spinal Neoplasms; Substance Withdrawal Syndrome; Thyroid Neoplasms | 1986 |
Activation of presynaptic alpha 2-adrenoceptors attenuates the inhibitory effect of mu-opioid receptor agonists on noradrenaline release from brain slices.
Topics: Animals; Brain Chemistry; Cadmium; Clonidine; Colforsin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu | 1986 |
Intrathecal morphine tolerance: use of intrathecal clonidine, DADLE, and intraventricular morphine.
Topics: Adenocarcinoma; Bupivacaine; Clonidine; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Humans; Infusions, Parenteral; Injections, Intraventricular; Injections, Spinal; Middle Aged; Morphine; Nerve Block; Pain, Intractable; Pelvic Neoplasms; Terminal Care | 1985 |
Gangliosides as modulators of the coupling of neurotransmitters to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Brain; Cell Line; Clonidine; Cricetinae; Cricetulus; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Gangliosides; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Neurons; Neurotransmitter Agents; Receptors, Serotonin | 1984 |
Effects of opiate and alpha 2-adrenergic agonists in a neuroblastoma x brain explant hybrid cell line (NCB-20).
Topics: Adrenergic alpha-Agonists; Alprostadil; Animals; Brain; Cell Line; Clonidine; Cricetinae; Cricetulus; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Mice; Narcotics; Neuroblastoma; Neurons; Prostaglandins E | 1984 |
Chronic exposure of NG 108-15 cells to inhibitory acting drugs reduces stimulatory prostaglandin E1 receptor number.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Animals; Binding, Competitive; Cattle; Clonidine; Enkephalin, Leucine-2-Alanine; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Muscarinic Agonists; Naloxone; Narcotic Antagonists; Neuroblastoma; Oxotremorine; Pertussis Toxin; Receptors, Opioid, delta; Receptors, Prostaglandin E; Virulence Factors, Bordetella | 1996 |
Functional evidence that gastroprotection can be induced by activation of central alpha(2B)-adrenoceptor subtypes in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Enkephalin, Leucine-2-Alanine; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 2000 |
Gyrus cinguli transection abolishes delta-opioid receptor-induced gastroprotection and alters alpha 2 adrenoceptor activity in the lower brainstem in rats.
Topics: Adrenalectomy; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain Stem; Cisterna Magna; Clonidine; Corticosterone; Enkephalin, Leucine-2-Alanine; Ethanol; Gyrus Cinguli; Hypothalamo-Hypophyseal System; Limbic System; Male; Microinjections; Rats; Rats, Wistar; Receptors, Opioid, delta; Solvents; Stomach Ulcer | 2002 |