clonidine and enalapril

clonidine has been researched along with enalapril in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's6 (21.43)18.2507
2000's7 (25.00)29.6817
2010's9 (32.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hamlin, RL; Jenkins, JE; Jurin, RR; McCune, SA; Radin, MJ1
Antonucci, F; Favazza, A; Gropuzzo, M; Messa, P; Mioni, G; Motanaro, D1
Cook, E; Dillard, D; Lewin, A; Wallin, JD; Weidler, D1
Bakris, GL; Sauter, ER1
Klepzig, M; Motz, W; Strauer, BE1
Bähr, M; Langewitz, W; Rüddel, H; Schächinger, H; Schmieder, RE; Schulte, W1
Bähr, M; Langewitz, W; Rüddel, H; Schmieder, RE; Schulte, W1
Fettman, MJ; Tan, AA; Wilke, WL1
Andersson, RG; Grundström, N; Lindgren, BR1
Anderson, CD; Andersson, RG; Frödin, T; Lindgren, BR1
Iro, H; Krause, J; Leuwer, A; Waldfahrer, F1
Bernhardt, AJ; Greendyke, RM; Lewandowski, KS; Tasbas, HE1
Amador, N; Guízar, JM; Lara, S; Malacara, JM; Paniagua, R; Pérez-Luque, E1
Golikov, AP1
Anania, V; Antuofermo, E; Baralla, E; Deiana, G; Demontis, MP; Macciotta, NP; Palomba, D; Varoni, MV1
Abdel-Rahman, AA; El-Mas, MM1
Cheng, YQ; Lin, LL; Liu, AJ; Su, DF; Wang, D; Wang, W1

Reviews

1 review(s) available for clonidine and enalapril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for clonidine and enalapril

ArticleYear
Peritoneal clearances in hypertensive CAPD patients after oral administration of clonidine, enalapril, and nifedipine.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1992, Volume: 12, Issue:3

    Topics: Biological Transport; Clonidine; Enalapril; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum

1992
Transdermal clonidine as an adjunct to enalapril: an evaluation of efficacy and patient compliance.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Clonidine; Drug Therapy, Combination; Enalapril; Female; Humans; Male; Middle Aged; Patient Compliance

1992
Efficacy of four antihypertensive drugs (clonidine, enalapril, nitrendipine, oxprenolol) on stress blood pressure.
    The American journal of cardiology, 1989, Jun-01, Volume: 63, Issue:18

    Topics: Adult; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Enalapril; Exercise Test; Humans; Hypertension; Male; Monitoring, Physiologic; Nitrendipine; Oxprenolol; Stress, Physiological; Stress, Psychological

1989
Disparities in blood pressure control under various antihypertensive regimens.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Clonidine; Enalapril; Exercise Test; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nitrendipine; Oxprenolol

1989
Polydipsia in chronic psychiatric patients: therapeutic trials of clonidine and enalapril.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:4

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antipsychotic Agents; Chronic Disease; Clonidine; Cross-Over Studies; Double-Blind Method; Drinking Behavior; Drug Therapy, Combination; Enalapril; Female; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology

1998
Leptin and heart sympathetic activity in normotensive obese and non-obese subjects.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2004, Volume: 5, Issue:1

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Pressure; Body Mass Index; Clonidine; Diastole; Enalapril; Female; Heart Rate; Humans; Hypertension; Leptin; Male; Middle Aged; Obesity; Statistics as Topic; Systole; Treatment Outcome

2004

Other Studies

21 other study(ies) available for clonidine and enalapril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Effects of enalapril and clonidine on glomerular structure, function, and atrial natriuretic peptide receptors in SHHF/Mcc-cp rats.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Binding Sites; Clonidine; Cyclic GMP; Enalapril; Hypertension; Hypertrophy; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface

1992
The effects of enalapril on urinary protein excretion in patients with idiopathic membranous nephropathy.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:2

    Topics: Adult; Blood Pressure; Clonidine; Enalapril; Female; Glomerulonephritis, Membranous; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Proteinuria

1990
Regression of cardiac hypertrophy: experimental and clinical results.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 6

    Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats, Inbred SHR

1987
Effect of clonidine on the progression of chronic renal disease in partially nephrectomized rats.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:2

    Topics: Animals; Blood Pressure; Chronic Disease; Clonidine; Creatinine; Enalapril; Heart; Kidney; Kidney Diseases; Male; Nephrectomy; Organ Size; Proteinuria; Rats; Rats, Inbred Strains

1987
Effects of an alpha-2 adrenoceptor agonist on angiotensin converting enzyme inhibitor-induced hypotension and potentiated allergen-evoked inflammatory skin responses.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Adrenergic alpha-Agonists; Allergens; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Clonidine; Enalapril; Enalaprilat; Female; Guinea Pigs; Inflammation; Skin Tests

1988
Effects of some antihypertensive drugs on cutaneous blood flow and inflammatory skin responses following allergen challenge in guinea pigs.
    Pharmacology & toxicology, 1987, Volume: 60, Issue:5

    Topics: Allergens; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Clonidine; Dermatitis; Enalapril; Enalaprilat; Female; Guinea Pigs; Ovalbumin; Prazosin; Regional Blood Flow; Skin

1987
[Severe oropharyngeal angioedema caused by ACE inhibitor. A case report].
    HNO, 1995, Volume: 43, Issue:1

    Topics: Angioedema; Clemastine; Clonidine; Combined Modality Therapy; Drug Hypersensitivity; Emergencies; Enalapril; Humans; Hypertension, Renal; Laryngeal Edema; Male; Middle Aged; Prednisolone; Ranitidine; Tracheotomy

1995
[Comparative assessment of results of treatment of hipertensive crises with enalapril and clonidine.].
    Kardiologiia, 2004, Volume: 44, Issue:11

    Topics: Clonidine; Enalapril; Humans; Hypertension

2004
Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats.
    Drug and chemical toxicology, 2010, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Cadmium; Captopril; Clonidine; Enalapril; Heart; Histocytochemistry; Hypertension; Kallikrein-Kinin System; Kallikreins; Kidney; Male; Rats; Rats, Wistar; Renin-Angiotensin System; Saralasin

2010
Bradykinin B2 receptor-dependent enhancement of enalapril-evoked hypotension in ethanol-fed female rats.
    Journal of cardiovascular pharmacology, 2011, Volume: 57, Issue:1

    Topics: Animals; Baroreflex; Bradykinin; Clonidine; Enalapril; Ethanol; Female; Hemodynamics; Hydralazine; Hypotension; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Telemetry

2011
Long-term treatment of clonidine, atenolol, amlodipine and dihydrochlorothiazide, but not enalapril, impairs the sexual function in male spontaneously hypertensive rats.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Animals; Antihypertensive Agents; Atenolol; Clonidine; Drug Administration Schedule; Enalapril; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Sexual Dysfunction, Physiological

2015