clonidine and dronabinol

clonidine has been researched along with dronabinol in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's5 (18.52)18.2507
2000's10 (37.04)29.6817
2010's7 (25.93)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Daskalopoulos, N; Laubie, M; Schmitt, H1
Dalterio, S; de Paolo, L; Peluso, J; Steger, R1
Hopkins, GA1
Hermans, AJ; Innemee, HC; van Zwieten, PA1
Mechoulam, R; Ovadia, H; Weidenfeld, J; Wohlman, A1
Griffin, G; Pertwee, RG1
Dallaporta, M; Himmi, T; Orsini, JC; Perrin, J1
Fernando, SR; Pertwee, RG1
Jentsch, JD; Katz, Z; Roth, RH; Wise, A1
Bar-Ilan, A; Beilin, M; Belkin, M; Green, K; Neumann, R1
Baillie, G; Pertwee, RG; Price, MR; Ross, RA; Stevenson, LA; Thomas, A; Wease, KN1
Gessa, GL; Melis, M; Muntoni, AL; Perra, S; Pillolla, G; Pistis, M1
Comer, SD; Foltin, RW; Haney, M; Hart, CL; Reed, SC; Vosburg, SK1
McMahon, LR; Stewart, JL1
Bisaga, A; Brooks, D; Carpenter, KM; Choi, JC; Dakwar, E; Glass, A; Levin, FR; Mahony, A; Mariani, JJ; Nunes, EV; Pavlicova, M; Sullivan, MA1
Álvarez-Ossorio, L; Haupts, M; Jonas, A; Vila, C; Witte, K1
Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P1
Brezing, CA; Brooks, D; Choi, CJ; Levin, FR; Mahony, AL; Mariani, JJ; Pavlicova, M1
Jones, É; Vlachou, S1

Reviews

4 review(s) available for clonidine and dronabinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug treatment of glaucoma.
    American journal of optometry and physiological optics, 1984, Volume: 61, Issue:12

    Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Bromocriptine; Clonidine; Dronabinol; Epinephrine; Glaucoma; Humans; Labetalol; Miotics; Nadolol; Parasympathomimetics; Pilocarpine; Propanolamines; Sympathomimetics; Timolol

1984
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:11

    Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol

2016
A Critical Review of the Role of the Cannabinoid Compounds Δ
    Molecules (Basel, Switzerland), 2020, Oct-25, Volume: 25, Issue:21

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Baclofen; Cannabidiol; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Approval; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Multiple Sclerosis; Spinal Cord; Treatment Outcome; United States; United States Food and Drug Administration

2020

Trials

4 trial(s) available for clonidine and dronabinol

ArticleYear
Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse.
    Psychopharmacology, 2008, Volume: 197, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Affect; Appetite; Attention; Cannabinoids; Clonidine; Double-Blind Method; Dronabinol; Drug Therapy, Combination; Humans; Male; Marijuana Abuse; Mental Recall; Psychomotor Performance; Psychotropic Drugs; Secondary Prevention; Sleep; Substance Withdrawal Syndrome

2008
Dronabinol and lofexidine for cannabis use disorder: A randomized, double-blind, placebo-controlled trial.
    Drug and alcohol dependence, 2016, Feb-01, Volume: 159

    Topics: Adolescent; Adult; Cannabinoid Receptor Agonists; Clonidine; Craving; Double-Blind Method; Dronabinol; Female; Humans; Male; Marijuana Abuse; Medication Adherence; Middle Aged; Narcotic Antagonists; Secondary Prevention; Substance Withdrawal Syndrome

2016
Influence of Previous Failed Antispasticity Therapy on the Efficacy and Tolerability of THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity.
    European neurology, 2016, Volume: 75, Issue:5-6

    Topics: Adult; Baclofen; Cannabidiol; Clonidine; Dronabinol; Drug Combinations; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Parasympatholytics; Plant Extracts

2016
Abstinence and reduced frequency of use are associated with improvements in quality of life among treatment-seekers with cannabis use disorder.
    The American journal on addictions, 2018, Volume: 27, Issue:2

    Topics: Adult; Clonidine; Double-Blind Method; Dronabinol; Female; Humans; Male; Marijuana Abuse; Marijuana Smoking; Middle Aged; Motivation; Narcotic Antagonists; Quality of Life; Sex Factors; Smoking Reduction; Surveys and Questionnaires; Temperance; Treatment Outcome

2018

Other Studies

19 other study(ies) available for clonidine and dronabinol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Action of delta 9 tetrahydrocannabinol on the central cardiovascular regulation : mechanism and localization].
    L'Encephale, 1975, Volume: 1, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cannabis; Cardiovascular System; Cats; Clonidine; Dogs; Dronabinol; Electric Stimulation; Evoked Potentials; Fentanyl; Heart Rate; Hypothalamus; Medulla Oblongata; Morphine Derivatives; Nalorphine; Naloxone; Sciatic Nerve; Splanchnic Nerves; Spleen

1975
Acute delta 9-tetrahydrocannabinol exposure: effects on hypothalamic-pituitary-testicular activity in mice.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:3

    Topics: Animals; Chorionic Gonadotropin; Clonidine; Dronabinol; Ethanol; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Median Eminence; Mice; Mice, Inbred Strains; Norepinephrine; Pituitary Gland; Testis; Testosterone

1987
The influence of delta 9-tetrahydrocannabinol on intraocular pressure in the anaesthetized cat.
    Documenta ophthalmologica. Advances in ophthalmology, 1980, Apr-15, Volume: 48, Issue:2

    Topics: Animals; Brain Stem; Cats; Clonidine; Dose-Response Relationship, Drug; Dronabinol; Female; Hypotension; Injections, Intra-Arterial; Injections, Intravenous; Intraocular Pressure; Male; Sympathetic Nervous System; Vertebral Artery

1980
Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens.
    Neuropharmacology, 1995, Volume: 34, Issue:2

    Topics: Animals; Cannabinoids; Clonidine; Dinoprostone; Dose-Response Relationship, Drug; Dronabinol; Humans; Hypothermia; Interleukin-1; Male; Pyrogens; Rats; Temperature; Time Factors

1995
A preliminary investigation of the mechanisms underlying cannabinoid tolerance in the mouse vas deferens.
    European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Clonidine; Dose-Response Relationship, Drug; Down-Regulation; Dronabinol; Drug Tolerance; Electric Stimulation; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Receptors, Opioid; Vas Deferens

1995
Neuronal responses to delta 9-tetrahydrocannabinol in the solitary tract nucleus.
    European journal of pharmacology, 1996, Oct-03, Volume: 312, Issue:3

    Topics: Animals; Biguanides; Clonidine; Dronabinol; Glucose; In Vitro Techniques; Male; Neurons; Rats; Rats, Wistar; Solitary Nucleus

1996
Evidence that methyl arachidonyl fluorophosphonate is an irreversible cannabinoid receptor antagonist.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Animals; Arachidonic Acids; Clonidine; Dose-Response Relationship, Drug; Dronabinol; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Organophosphonates; Receptors, Cannabinoid; Receptors, Drug

1997
Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Guanfacine; Hallucinogens; Male; Nucleus Accumbens; Phencyclidine; Prazosin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha

1998
Pharmacology of the intraocular pressure (IOP) lowering effect of systemic dexanabinol (HU-211), a non-psychotropic cannabinoid.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:3

    Topics: Animals; Aqueous Humor; Blood Pressure; Cannabinoids; Clonidine; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Fluorophotometry; Heart Rate; Injections, Intravenous; Intraocular Pressure; Male; Propranolol; Pupil; Rabbits

2000
Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist.
    British journal of pharmacology, 2005, Volume: 146, Issue:7

    Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Cannabis; CHO Cells; Clonidine; Cricetinae; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Vas Deferens

2005
Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons.
    The European journal of neuroscience, 2006, Volume: 23, Issue:9

    Topics: Action Potentials; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Clonidine; Dose-Response Relationship, Drug; Dronabinol; Locus Coeruleus; Male; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Norepinephrine; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant

2006
Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:1

    Topics: Adrenergic Agonists; Animals; Behavior, Animal; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Clonidine; Cyclohexanols; Discrimination, Psychological; Dronabinol; Female; Heart Rate; Macaca mulatta; Male; Morpholines; Motor Activity; Naphthalenes; Piperidines; Pyrazoles; Rimonabant; Substance Withdrawal Syndrome

2010