clonidine has been researched along with diphenhydramine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 12 (48.00) | 29.6817 |
| 2010's | 7 (28.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Dinnendahl, V; Gumulka, SW | 1 |
| Rivier, C; Vale, W | 1 |
| Fernandez-Alfonso, MS; Marín, J; Reviriego, J | 1 |
| Karppanen, HO; Westermann, E | 1 |
| Redfern, WS; Williams, A | 1 |
| Hushcha, TO; Luik, AI; Mischenko, NI; Mogilevich, SE | 1 |
| Cummings, MR; Miller, BD | 1 |
| Inazu, M; Matsumiya, T; Tajima, H; Takeda, H; Uchida, Y; Yamada, T | 1 |
| André, P; Cisternino, S; Debray, M; Scherrmann, JM | 1 |
| André, P; Chapy, H; Cisternino, S; Declèves, X; Scherrmann, JM | 1 |
| Duncan-Wiebe, G; LeRiger, M; Shukry, M; Williams, J | 1 |
2 review(s) available for clonidine and diphenhydramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacologic management of behavioral instability in medically ill pediatric patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Aggression; Analgesics, Non-Narcotic; Behavior Therapy; Behavioral Medicine; Benzodiazepines; Carbamazepine; Central Nervous System Stimulants; Child; Clonidine; Diphenhydramine; Histamine H1 Antagonists; Humans; Lithium; Methylphenidate; Psychomotor Agitation; Valproic Acid | 2004 |
23 other study(ies) available for clonidine and diphenhydramine
| Article | Year |
|---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Stress-induced alterations of cyclic nucleotide levels in brain: effects of centrally acting drugs.
Topics: Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Chlorpromazine; Clonidine; Cyclic AMP; Cyclic GMP; Diazepam; Diphenhydramine; Haloperidol; Indomethacin; Male; Mice; Pentobarbital; Phentolamine; Propanolamines; Propranolol; Reserpine; Stress, Physiological | 1977 |
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat.
Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone | 1977 |
Actions of vasoactive drugs on human placental vascular smooth muscle.
Topics: Arteries; Clonidine; Diphenhydramine; Dopamine; Female; Histamine; Humans; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Placenta; Pregnancy; Regional Blood Flow; Serotonin; Veins | 1990 |
Increased production of cyclic AMP in gastric tissue by stimulation of histamine2 (H2)-receptors.
Topics: Animals; Binding, Competitive; Clonidine; Cyclic AMP; Diphenhydramine; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Rats; Receptors, Drug; Theophylline; Thiourea | 1973 |
A re-evaluation of the role of alpha 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlordiazepoxide; Clonidine; Dioxanes; Diphenhydramine; Hypnotics and Sedatives; Idazoxan; Imidazoles; Injections, Subcutaneous; Isoquinolines; Male; Maze Learning; Mydriasis; Naphthyridines; Picrotoxin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Study of human serum albumin structure by dynamic light scattering: two types of reactions under different pH and interaction with physiologically active compounds.
Topics: Atropine; Carbachol; Chlorpromazine; Clonidine; Diphenhydramine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phenylephrine; Propranolol; Protein Binding; Scattering, Radiation; Serum Albumin; Yohimbine | 1998 |
Expression and functional characterization of choline transporter in human keratinocytes.
Topics: Acetylcholine; Anisoles; Antigens, CD; Biological Transport; Cell Membrane; Cells, Cultured; Choline; Clonidine; Desipramine; Diphenhydramine; Gene Expression Profiling; Humans; Keratinocytes; Membrane Potentials; Octamer Transcription Factor-3; Organic Cation Transport Proteins; p-Aminohippuric Acid; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tetraethylammonium; Time Factors; Tritium | 2009 |
Clonidine transport at the mouse blood-brain barrier by a new H+ antiporter that interacts with addictive drugs.
Topics: Analgesics; Animals; Antiporters; Biological Transport; Blood-Brain Barrier; Brain; Clonidine; Diphenhydramine; Drug Interactions; Hydrogen-Ion Concentration; Kinetics; Mice; Perfusion; Protons; Substance-Related Disorders | 2009 |
A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood-retinal barrier.
Topics: Animals; Antiporters; Biological Transport; Blood-Retinal Barrier; Clonidine; Diphenhydramine; Male; Mice; Mice, Knockout | 2015 |
Acute masseter dystonia in a pediatric patient receiving aripiprazole and methylphenidate following induction of general anesthesia.
Topics: Anesthesia, General; Antipsychotic Agents; Appendectomy; Aripiprazole; Central Nervous System Stimulants; Child; Clonidine; Diphenhydramine; Dystonia; Histamine H1 Antagonists; Humans; Male; Methylphenidate; Trismus | 2017 |