clonidine and dextromethorphan

clonidine has been researched along with dextromethorphan in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's4 (28.57)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW1
Koyuncuoglu, H1
Henretig, FM1
Dickenson, AH1
Amabeoku, GJ1
Ozek, M; Sevgi, S; Uresin, Y1
Baker, AK; Hoffmann, VL; Meert, TF1
Honarmand, A; Safavi, MR1
Isoherranen, N; Ke, AB; Nallani, SC; Rostami-Hodjegan, A; Unadkat, JD; Zhao, P1
Chen, CH; Lin, SK; Pan, CH1
Gaines, LA; Liebelt, E; Slattery, A1

Reviews

4 review(s) available for clonidine and dextromethorphan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Special considerations in the poisoned pediatric patient.
    Emergency medicine clinics of North America, 1994, Volume: 12, Issue:2

    Topics: Acetaminophen; Alcoholic Intoxication; Astemizole; Child; Child, Preschool; Clonidine; Cocaine; Critical Care; Dextromethorphan; Drug Overdose; Female; Humans; Hydrocarbons; Infant; Insecticides; Iron; Male; Organophosphorus Compounds; Poisoning

1994
Neurophysiology of opioid poorly responsive pain.
    Cancer surveys, 1994, Volume: 21

    Topics: Analgesics, Opioid; Animals; Central Nervous System; Clonidine; Dextromethorphan; Dextrorphan; Dynorphins; Humans; Morphine; N-Methylaspartate; Neoplasms; Neurophysiology; Neuroprotective Agents; Pain; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Sympatholytics

1994
Common ocular effects reported to a poison control center after systemic absorption of drugs in therapeutic and toxic doses.
    Current opinion in ophthalmology, 2014, Volume: 25, Issue:6

    Topics: Amphetamines; Analgesics, Opioid; Clonidine; Dextromethorphan; Humans; Miosis; Mydriasis; Nystagmus, Pathologic; Poison Control Centers; Substance-Related Disorders; United States

2014

Trials

2 trial(s) available for clonidine and dextromethorphan

ArticleYear
Preoperative oral dextromethorphan vs. clonidine to prevent tourniquet-induced cardiovascular responses in orthopaedic patients under general anaesthesia.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Analysis of Variance; Anesthesia, General; Antihypertensive Agents; Blood Pressure; Clonidine; Dextromethorphan; Double-Blind Method; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Monitoring, Physiologic; Orthopedic Procedures; Preoperative Care; Prospective Studies; Time Factors; Tourniquets

2007
A double-blind, placebo-controlled trial of dextromethorphan combined with clonidine in the treatment of heroin withdrawal.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:4

    Topics: Adult; Clonidine; Dextromethorphan; Double-Blind Method; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome

2014

Other Studies

8 other study(ies) available for clonidine and dextromethorphan

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017
The combination of tizanidine markedly improves the treatment with dextromethorphan of heroin addicted outpatients.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:1

    Topics: Adult; Ambulatory Care Facilities; Clonidine; Dextromethorphan; Drug Therapy, Combination; Female; Heroin Dependence; Hormones; Humans; Infant, Newborn; Male; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

1995
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
    General pharmacology, 1999, Volume: 32, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline

1999
Protective effects of dextromethorphan and tizanidine on ouabain-induced arrhythmias.
    Methods and findings in experimental and clinical pharmacology, 2002, Volume: 24, Issue:7

    Topics: Adrenergic alpha-Agonists; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Clonidine; Dextromethorphan; Excitatory Amino Acid Antagonists; Male; Ouabain; Rats; Rats, Wistar

2002
Interactions of NMDA antagonists and an alpha 2 agonist with mu, delta and kappa opioids in an acute nociception assay.
    Acta anaesthesiologica Belgica, 2002, Volume: 53, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Clonidine; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Ketamine; Male; Mice; Morphine; N-Methylaspartate; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Opioid

2002
A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorphan; Female; Humans; Models, Biological; Paroxetine; Pregnancy; Theophylline

2013