clonidine has been researched along with dexmedetomidine in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (2.88) | 18.2507 |
| 2000's | 46 (33.09) | 29.6817 |
| 2010's | 65 (46.76) | 24.3611 |
| 2020's | 24 (17.27) | 2.80 |
| Authors | Studies |
|---|---|
| Bonhaus, DW; Chang, LK; Chang, TK; Daunt, DA; Eglen, RM; Hsu, SA; Jasper, JR; Lesnick, JD; Yamanishi, SS | 1 |
| Peltonen, JM; Pihlavisto, M; Scheinin, M | 1 |
| Pihlavisto, M; Scheinin, M; Sjöholm, B; Wurster, S | 1 |
| Boyd, RE; Codd, EE; Connelly, CD; Jetter, MC; Lewis, MA; Martinez, RP; McDonnell, ME; Raffa, RB; Reitz, AB; Ross, TM | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Boblewski, K; Gdaniec, M; Hudson, AL; Kornicka, A; Laird, S; Laurila, JM; Lehmann, A; Rybczyńska, A; Sączewski, F; Scheinin, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Agbaba, D; Azzali, E; Costantino, G; Glisic, S; Laurila, JM; Nikolic, K; Perovic, V; Pieroni, M; Radi, M; Scheinin, M; Srdic-Rajic, T; Tassini, S; Veljkovic, N; Vucicevic, J | 1 |
| Pihlavisto, M; Scheinin, M | 1 |
| Asano, T; Dohi, S; Iida, H; Ohta, S; Shimonaka, H | 1 |
| Graham, BA; Hammond, DL; Proudfit, HK | 1 |
| Aggarwall, A; Chen, R; Cheung, A; Gottlieb, A; Heard, S; Kallio, A; Son, SL; Talke, P; Thomas, B; Thorborg, P | 1 |
| Dohi, S; Iida, H; Iida, M; Takenaka, M | 1 |
| Onttonen, T; Pertovaara, A | 1 |
| Audinot, V; Boutin, JA; Cordi, A; Cussac, D; Dekeyne, A; Duqueyroix, D; Girardon, S; Lacoste, JM; Millan, MJ; Milligan, G; Mullot, J; Newman-Tancredi, A; Nicolas, JP; Renouard-Try, A | 1 |
| Auclair, A; Bosc, C; Brocco, M; Cordi, A; Dekeyne, A; Gobert, A; Lacoste, JM; Lejeune, F; Millan, MJ; Rivet, JM | 1 |
| Desmonts, JM; Evrard, P; Gressens, P; Lagercrantz, H; Laudenbach, V; Mantz, J | 1 |
| Boyle, WA; Hamasaki, J; Hidaka, T; Kanmura, Y; Katai, R; Tsuneyoshi, I | 1 |
| Kobilka, BK; Limbird, LE; MacMillan, LB; Tan, CM; Wilson, MH | 1 |
| Herbert, MK; Holzer, P; Roewer, N; Roth-Goldbrunner, S | 1 |
| Kalso, E; Paloheimo, M; Talke, P; Xu, M | 1 |
| Beattie, WS; Naik, JS; Wijeysundera, DN | 1 |
| Serlin, S | 1 |
| Kallio, J; Olli-Lähdesmäki, T; Scheinin, M; Tiger, M; Vainio, M | 1 |
| Boussofara, M; Kaddour, C; Mtaallah, MH; Nefaa, MN | 1 |
| Kwek, K; Sia, AT; Yeo, GS | 1 |
| Dinenno, FA; Eisenach, JH; Joyner, MJ; Masuki, S | 1 |
| Tobias, JD | 1 |
| Al Jazzar, MD; Al-Yaman, R; Alameddine, MM; Aouad, MT; Baraka, AS; Bulbul, M; Jabbour-Khoury, SI; Kanazi, GE | 1 |
| Aantaa, R; Jalonen, J | 1 |
| Bachmann, H; Elwert, R; Hachenberg, T; Halloul, Z; Schneemilch, CE; Ulrich, A | 1 |
| Kawamata, M; Namiki, A; Narimatsu, E; Niiya, T | 1 |
| Auler, JO; Bandeira, D; Bertacchi, MF; Schmidt, AP; Simões, CM; Valinetti, EA | 1 |
| Dohi, S; Iida, H; Oda, A; Osawa, Y; Tanahashi, S; Yamaguchi, S | 1 |
| Boots, R; Deans, R; Freshwater-Turner, D; Hegde, R; Lipman, J; McWhinney, BC; Stuart, J; Udy, A | 1 |
| Iwasaki, S; Namiki, A; Satoh, JI; Yamakage, M | 1 |
| Greenhalgh, DL; Kumar, CM | 1 |
| Billings, FT; Chen, SW; D'Agati, V; Herman, J; Kim, M; Lee, HT; Park, SW; Song, JH; Wang, S | 1 |
| Bruzzone, A; Castillo, LF; Lanari, C; Lüthy, IA; Piñero, CP; Rojas, P; Sarappa, MG | 1 |
| Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T | 1 |
| Christianson, CA; Hua, XY; Nazarian, A; Yaksh, TL | 1 |
| Camarini, ET; Coelho, L; de Moraes, M; Farah, GJ; Filho, LI; Pavan, AJ; Previdelli, IT | 1 |
| Fairbanks, CA; Kitto, KF; Nguyen, HO; Stone, LS; Wilcox, GL | 1 |
| Chalikonda, SA | 1 |
| Abd-Elmaksoud, AM; Abd-Elwahab, AM; Boulis, SR; El-Hennawy, AM; El-Ozairy, HS | 1 |
| Bilge, SS; Bostanci, MO; Bozkurt, A; Ciftcioglu, E; Dilek, A; Güldogus, F; Ilkaya, F; Ulger, F | 1 |
| Benefield, RJ; Honey, BL; Johnson, PN; Miller, JL | 1 |
| Congedo, E; De Cosmo, G; Sgreccia, M | 1 |
| Minhas, A; Suresh, S | 1 |
| Beattie, WS; Bender, JS; Wijeysundera, DN | 1 |
| Haapalinna, A; Lehtimäki, J; Leino, T; Viitamaa, T; Virtanen, R | 1 |
| Amodeo, FS; Brummett, CM; Lydic, R; Padda, AK; Welch, KB | 1 |
| Cook, AM; Humphries, RL; Martin, JE; Weant, KA | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Chilipko, A; Fowler, JA; Muzyk, AJ; Norwood, DK | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Kasaba, T | 1 |
| Brummett, CM; Williams, BA | 1 |
| Hilaire, G; Quintin, L; Voituron, N | 1 |
| Anitescu, M; Patil, SK | 1 |
| Gao, XM; Leng, YF; Wang, SX; Xing, YH | 1 |
| Blaudszun, G; Elia, N; Lysakowski, C; Tramèr, MR | 1 |
| Ajiki, K; Hayami, N; Kanamori, K; Kunishima, T; Mikamo, T; Murakawa, Y; Sugiura, A; Tsutsui, K; Watanabe, H; Yamagishi, N; Yamagishi, S | 1 |
| Ghignone, M; Longrois, D; Pichot, C; Quintin, L | 1 |
| Coker, S; Kukoyi, A; Lewis, L; Nierenberg, D | 1 |
| Batra, YK; Bharti, N; Jain, A; Kumar, P; Nikhar, SA; Solanki, SL | 1 |
| Ghignone, M; Petitjeans, F; Pichot, C; Quintin, L | 1 |
| Ashokkumar, H; Kuppuswamy, B; Mariappan, R | 1 |
| Chapelier, K; Cividjian, A; Dantony, E; Geloen, A; May, CN; Quintin, L; Rabilloud, M | 1 |
| Dünser, MW; Gradwohl-Matis, I | 1 |
| Bailard, NS; Flores, RA; Ortiz, J | 1 |
| Brichant, JF; Mavropoulos, G; Minguet, G | 1 |
| Beringer, R; Birnie, K; Davies, P; Pickard, A | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
| Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P | 1 |
| Albertson, TE; Chenoweth, J; Ford, J; Owen, K; Sutter, ME | 1 |
| Huang, AJ; Li, AZ; Li, KZ; Li, Z; Qi, J; Shi, CX; Tian, M; Xin, DQ; Zhang, CY | 1 |
| Fraser, GL; Gagnon, DJ; Glisic, EK; Kelner, A; Perrey, HM; Riker, RR | 1 |
| Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC | 1 |
| Keating, GM | 1 |
| Dohlman, JC; Kohane, DS; Kolovou, PE; McAlvin, JB; Salvador-Culla, B; Zhan, C | 1 |
| Alderson, P; Lewis, SR; Nicholson, A; Smith, AF | 1 |
| Brenner, T; Hackert, T; Hofer, S; Jabrailova, B; Kilk, K; Salem, M; Schneider, L; Strobel, O; Werner, J | 1 |
| Li, C; Mi, W; Pirrone, M; Sun, L; Zhang, C | 1 |
| Breatnach, C; Cousins, G; Doherty, DR; Gallagher, PJ; Hayden, JC; Healy, M; Howlett, MM | 1 |
| Géloën, A; Ghignone, M; Julien, C; Leroy, S; May, CN; Pichot, C; Quintin, L | 1 |
| Aggarwal, S; Gupta, KK; Jindal, S; Kaur, G; Sidhu, GK; Singh, G | 1 |
| Hara, M; Hemmings, HC; Zhou, ZY | 1 |
| Kakkar, A; Nabi, N; Sethi, AK; Tyagi, A; Verma, UC | 1 |
| Blinder, H; English, S; Hutton, B; Tran, A | 1 |
| Gaspar-Carrillo, SP; Mejía-Terrazas, GE; Peña-Riveron, AA; Velázquez-Delgado, E | 1 |
| Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S | 1 |
| Anghelescu, DL; Moore, AD | 1 |
| Bissell, BD; Ferreira, JA | 1 |
| Bruschettini, M; Calevo, MG; Norman, E; Romantsik, O | 1 |
| Abdallah, FW; Brull, R; El-Boghdadly, K; Sehmbi, H | 1 |
| Nguyen, V; Park, E; Salehi, A; Tiemann, D | 1 |
| Breatnach, C; Cousins, G; Dawkins, I; Doherty, DR; Foxton, J; Gallagher, PJ; Hayden, JC; Healy, M; Leacy, FP | 1 |
| Barnes, E; Kaufmann, H; Norcliffe-Kaufmann, L; Palma, JA; Spalink, CL | 1 |
| Costa, LR; Costa, PS; Daher, A; Maia, LC; Martins, CC; Paiva, SM; Viana, KA | 1 |
| Ferreira, J | 1 |
| Beattie, WS; Duncan, D; Sankar, A; Wijeysundera, DN | 1 |
| Gupta, N; Hayaran, N; Jain, A; Kumar, A; Mishra, P | 1 |
| Bhalla, T; Jayanthi, VR; Tobias, JD; Trifa, M; Tumin, D; Whitaker, EE | 1 |
| Berlière, M; De Kock, M; Forget, P; Poncelet, A | 1 |
| Al Anany, R; Elshafei, M; Gazwi, K; Mahmoud, S; Mohamed, A; Saad, MO | 1 |
| Kamat, PP; Kudchadkar, SR | 1 |
| Breatnach, CV; Cousins, G; Dawkins, I; Doherty, DR; Gallagher, PJ; Hayden, JC; Healy, M; Leacy, FP | 1 |
| Kobayashi, K; Kohase, H; Nagasaka, H; Ohno, S; Sakagami, H; Uchida, S | 1 |
| Bernal-Sprekelsen, M; Cardesín, A; Escamilla, Y; Fradera, M; Izquierdo, A; López, S; Pontes, C; Samara, L; Vives, R | 1 |
| Sun, S; Tan, D; Wang, F; Xia, H | 1 |
| Antunes, T; Demiri, M; Fletcher, D; Martinez, V | 1 |
| Donato, J; Lewis, T; Rao, K | 1 |
| Ali, I; Shokri, H | 1 |
| Baillie, JK; Edwardson, SA; Flanders, CA; Rocke, AS; Walsh, TS | 1 |
| Attridge, RL; Christina Gutierrez, G; Glaess, SS | 1 |
| Song, X; Wang, J; Wang, N; Wang, Z | 1 |
| Amin, AH; Hamed, E; Herdan, R; Mostafa, MF | 1 |
| Dong, Y; Li, M; Liang, F; Soriano, SG; Sun, M; Xie, Z; Zhang, J; Zhang, Y | 1 |
| Abbott, TEF; Ackland, GL; Weber, V | 1 |
| Bellomo, R; Deane, AM; Lankadeva, YR; May, CN; Plummer, MP; Shehabi, Y | 1 |
| Li, C; Ma, H; Mueller, A; Wang, D; Wang, J; Xuan, C; Yan, W | 1 |
| Jiang, L; Li, J; Wang, X; Yu, D | 1 |
| Bhatt, R; Bhutia, O; Goswami, D; Lakshmanan, S; Roychoudhury, A; Yadav, P | 1 |
| Bromfalk, Å; Engström, Å; Hultin, M; Myrberg, T; Walldén, J | 2 |
| Andersen, JH; Dahl, JB; Geisler, A; Grevstad, U; Jaeger, P; Karlsen, A; Mathiesen, O | 1 |
| Belliveau, M; Ghignone, M; Kock, M; Lieutaud, T; Longrois, D; Petitjeans, F; Pichot, C; Quintin, L; Simonet, O | 1 |
| Al Assadi, S; Kanazi, G; Karam, C; Zeeni, C | 1 |
| Abrard, S; Berlier, J; Bouffard, Y; Carabalona, JF; Cerro, V; Le-Goff, MC; Rimmelé, T; Subtil, F; Tête, H | 1 |
| Busund, R; Haaverstad, R; Helbostad, JL; Landsverk, SA; Martinaityte, I; Neerland, BE; Norum, HM; Ræder, J; Selbaek, G; Simpson, MR; Skaar, E; Skjærvold, NK; Skovlund, E; Slooter, AJ; Svendsen, ØS; Tønnessen, T; Wahba, A; Wyller, TB; Zetterberg, H | 1 |
| Huang, RR; Li, YL; Qu, SS; Yang, CQ; Yu, KH; Zhang, JM | 1 |
| Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN | 1 |
| Bäcke, P; Bruschettini, M; Olsson, E; Sibrecht, G; Thernström Blomqvist, Y | 1 |
| Fu, Y; Jiang, Y; Lang, B; Zhang, Q | 1 |
| Dersch-Mills, D; Howlett, A; Lind, J; Marchuk, A; Mohammad, K | 1 |
| Bodenbender, JP; Dinges, HC; Eberhart, L; Paul, C; Schubert, AK; Schubert, F; Wiesmann, T | 1 |
| Ben-Hamouda, N; Chiche, JD; Gavino, L; Willaredt, M | 1 |
49 review(s) available for clonidine and dexmedetomidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis.
Topics: Adrenergic alpha-Agonists; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Clonidine; Dexmedetomidine; Humans; Imidazoles; Myocardial Infarction; Perioperative Care; Preoperative Care; Randomized Controlled Trials as Topic; Registries | 2003 |
[Clonidine and anesthesia].
Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Local; Clonidine; Dexmedetomidine; Drug Interactions; Hemodynamics; Humans; Hypnotics and Sedatives; Imidazoles; Injections, Epidural; Injections, Spinal; Intraoperative Complications; Intubation, Intratracheal; Myocardial Ischemia; Preanesthetic Medication; Risk Factors; Sympatholytics; Time Factors | 2004 |
Perioperative use of alpha2-adrenoceptor agonists and the cardiac patient.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Cardiovascular Physiological Phenomena; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Perioperative Care | 2006 |
Sedation during ophthalmic surgery.
Topics: Analgesics, Opioid; Anesthesia, Local; Anesthetics, Intravenous; Benzodiazepines; Catheterization, Peripheral; Clonidine; Conscious Sedation; Contraindications; Dexmedetomidine; Humans; Monitoring, Intraoperative; Ophthalmologic Surgical Procedures | 2008 |
Alpha2-adrenergic agonists and their role in the prevention of perioperative adverse cardiac events.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Humans; Imidazoles; Myocardial Ischemia; Postoperative Complications | 2009 |
Alpha2-receptor agonists for treatment and prevention of iatrogenic opioid abstinence syndrome in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Child; Clonidine; Critical Illness; Dexmedetomidine; Drug Tolerance; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2009 |
New drugs for epidural analgesia.
Topics: Analgesia, Epidural; Analgesics; Clonidine; Dexmedetomidine; Humans; Ketamine; Neostigmine | 2009 |
Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoperative Complications; Postoperative Complications; Randomized Controlled Trials as Topic; Stress, Physiological; Surgical Procedures, Operative | 2009 |
Pharmacologic options for reducing the shivering response to therapeutic hypothermia.
Topics: Body Temperature; Clonidine; Dexmedetomidine; Humans; Hypothermia, Induced; Meperidine; Pharmacists; Shivering | 2010 |
Role of α2-agonists in the treatment of acute alcohol withdrawal.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Ethanol; Humans; Norepinephrine; Substance Withdrawal Syndrome | 2011 |
[Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia].
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Dexmedetomidine; Droperidol; Drug Compounding; Epinephrine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium Sulfate; Midazolam; Morphine; Neostigmine | 2010 |
Additives to local anesthetics for peripheral nerve blockade.
Topics: Anesthetics, Local; Buprenorphine; Clonidine; Dexmedetomidine; Epinephrine; Humans; Midazolam; Nerve Block; Sodium Bicarbonate; Tramadol | 2011 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dexmedetomidine; Hemodynamics; Humans; Hyperalgesia; Hypotension; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic | 2012 |
[Dexmedetomidine and clonidine: a review of their pharmacodynamy to define their role for sedation in intensive care patients].
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Cardiovascular System; Clonidine; Critical Care; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Respiration | 2012 |
Additives to local anesthetics for peripheral nerve blocks: Evidence, limitations, and recommendations.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Buprenorphine; Clonidine; Dexamethasone; Dexmedetomidine; Drug Combinations; Epinephrine; Evidence-Based Medicine; Humans; Ketamine; Magnesium Compounds; Midazolam; Nerve Block; Peripheral Nerves; Sodium Bicarbonate; Tramadol; Vasoconstrictor Agents | 2014 |
[Alpha-2 adrenoreceptor agonists in anaesthesia and intensive care medicine].
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Clonidine; Critical Care; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anesthesia, General; Child; Child Behavior; Child, Preschool; Clonidine; Delirium; Dexmedetomidine; Female; Humans; Infant; Intraoperative Care; Male; Postoperative Complications; Postoperative Period; Randomized Controlled Trials as Topic; Time Factors | 2014 |
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Clonidine; Desflurane; Dexmedetomidine; Halothane; Humans; Isoflurane; Methyl Ethers; Midazolam; Propofol; Sevoflurane | 2014 |
Is it prime time for alpha2-adrenocepter agonists in the treatment of withdrawal syndromes?
Topics: Adrenergic alpha-2 Receptor Agonists; Alcoholism; Clonidine; Dexmedetomidine; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2014 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; Hypnotics and Sedatives; Propofol | 2015 |
Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, General; Clonidine; Dexmedetomidine; Humans; Hypothermia; Randomized Controlled Trials as Topic; Shivering | 2015 |
Comparison of Dexmedetomidine and Clonidine as Adjuvants to Local Anesthetics for Intrathecal Anesthesia: A Meta-Analysis of Randomized Controlled Trials.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics; Anesthetics, Local; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Injections, Spinal; Randomized Controlled Trials as Topic | 2016 |
Efficacy of α2-Agonists for Sedation in Pediatric Critical Care: A Systematic Review.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Child; Child, Preschool; Clonidine; Conscious Sedation; Critical Care; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Pediatric; Male; Midazolam; Treatment Outcome | 2016 |
Pressor Response to Noradrenaline in the Setting of Septic Shock: Anything New under the Sun-Dexmedetomidine, Clonidine? A Minireview.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Humans; Inflammation; Multiple Organ Failure; Norepinephrine; Rats; Sheep; Shock, Septic | 2015 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence Delirium; Fentanyl; Humans; Incidence; Isoflurane; Ketamine; Methyl Ethers; Propofol; Sevoflurane | 2017 |
Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Catecholamines; Clonidine; Dexmedetomidine; Humans; Propanolamines; Sepsis; Shock, Septic; Stroke Volume; Sympathetic Nervous System; Sympatholytics; Tachycardia | 2018 |
Clonidine for sedation and analgesia for neonates receiving mechanical ventilation.
Topics: Cause of Death; Clonidine; Dexmedetomidine; Hospital Mortality; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Length of Stay; Randomized Controlled Trials as Topic; Respiration, Artificial | 2017 |
Perineural Dexmedetomidine Is More Effective Than Clonidine When Added to Local Anesthetic for Supraclavicular Brachial Plexus Block: A Systematic Review and Meta-analysis.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Brachial Plexus Block; Bradycardia; Chi-Square Distribution; Clonidine; Dexmedetomidine; Humans; Motor Activity; Odds Ratio; Pain Threshold; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Upper Extremity | 2017 |
Alpha-2 Agonists.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesia; Clonidine; Dexmedetomidine; Humans; Locus Coeruleus; Medulla Oblongata; Preanesthetic Medication | 2017 |
What is the level of evidence for the amnestic effects of sedatives in pediatric patients? A systematic review and meta-analyses.
Topics: Adolescent; Amnesia, Anterograde; Amnesia, Retrograde; Benzodiazepines; Child; Child, Preschool; Clonidine; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Male; Randomized Controlled Trials as Topic; Young Adult | 2017 |
The Theory is Out There: The Use of ALPHA-2 Agonists in Treatment of Septic Shock.
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Dexmedetomidine; Humans; Shock, Septic | 2018 |
Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoperative Complications; Myocardial Infarction; Postoperative Complications; Randomized Controlled Trials as Topic; Stress, Physiological; Stroke; Surgical Procedures, Operative | 2018 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theorem; Child; Clonidine; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Humans; Ketamine; Midazolam; Network Meta-Analysis; Ophthalmologic Surgical Procedures; Propofol; Psychomotor Agitation; Remifentanil; Sevoflurane; Sufentanil | 2019 |
Perioperative adverse events attributed to α2-adrenoceptor agonists in patients not at risk of cardiovascular events: systematic review and meta-analysis.
Topics: Adrenergic alpha-2 Receptor Agonists; Bradycardia; Clonidine; Dexmedetomidine; Humans; Hypotension; Intraoperative Complications; Postoperative Complications; Preoperative Period; Tachycardia | 2019 |
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modality Therapy; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Pain; Pain Management; Pharmacogenomic Variants; Precision Medicine; Remifentanil | 2019 |
The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Critical Illness; Dexmedetomidine; Disease Models, Animal; Humans; Inflammation | 2019 |
Clonidine as a strategy for discontinuing dexmedetomidine sedation in critically ill patients: A narrative review.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Substitution; Humans; Hypnotics and Sedatives; Risk Factors; Substance Withdrawal Syndrome | 2020 |
Intravenous dexmedetomidine versus intravenous clonidine for post spinal anesthesia shivering: a meta-analysis of randomized controlled trials.
Topics: Administration, Intravenous; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Spinal; Clonidine; Dexmedetomidine; Humans; Postoperative Complications; Randomized Controlled Trials as Topic; Shivering | 2020 |
Reducing the dose of neuromuscular blocking agents with adjuncts: a systematic review and meta-analysis.
Topics: Adjuvants, Pharmaceutic; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Magnesium; Neuromuscular Blockade; Neuromuscular Blocking Agents; Perioperative Care | 2021 |
Emerging benefits and drawbacks of α
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Clonidine; Critical Illness; Dexmedetomidine; Humans; Receptors, Adrenergic, alpha-2; Sepsis | 2021 |
The Facilitatory Effects of Adjuvant Pharmaceutics to Prolong the Duration of Local Anesthetic for Peripheral Nerve Block: A Systematic Review and Network Meta-analysis.
Topics: Adjuvants, Anesthesia; Anesthetics, Local; Clonidine; Dexmedetomidine; Drug Administration Schedule; Drug Interactions; Humans; Motor Activity; Nerve Block; Network Meta-Analysis; Peripheral Nervous System; Risk Assessment; Risk Factors; Sensory Thresholds; Time Factors | 2021 |
Alpha
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Brachial Plexus; Brachial Plexus Block; Clonidine; Dexmedetomidine; Humans | 2022 |
Comparison of different sedatives in children before general anaesthesia for selective surgery: A network meta-analysis.
Topics: Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Ketamine; Melatonin; Midazolam; Network Meta-Analysis | 2022 |
Pharmacological interventions for pain and sedation management in newborn infants undergoing therapeutic hypothermia.
Topics: Clonidine; Dexmedetomidine; Humans; Hypothermia, Induced; Infant, Newborn; Morphine Derivatives; Observational Studies as Topic; Pain | 2022 |
A comparative evaluation of intranasal α2-adrenoceptor agonists and intranasal midazolam as premedication in pediatric sedation: A meta-analysis of randomized controlled trials.
Topics: Administration, Intranasal; Anesthesia, General; Child; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Premedication; Randomized Controlled Trials as Topic; Receptors, Adrenergic | 2023 |
Efficacy of Adjuvants in Ophthalmic Regional Anesthesia: A Systematic Review and Network Meta-analysis.
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Fentanyl; Humans; Network Meta-Analysis | 2023 |
22 trial(s) available for clonidine and dexmedetomidine
| Article | Year |
|---|---|
The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Catecholamines; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Vascular Surgical Procedures | 2000 |
Selective alpha2-adrenergic properties of dexmedetomidine over clonidine in the human forearm.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Blood Flow Velocity; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Forearm; Humans; Injections, Intra-Arterial; Male; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Effect of low-dose dexmedetomidine or clonidine on the characteristics of bupivacaine spinal block.
Topics: Adrenergic alpha-Agonists; Aged; Analysis of Variance; Anesthesia, Spinal; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Clonidine; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Hemodynamics; Humans; Male; Nerve Block; Pain Measurement; Prospective Studies; Time Factors; Urogenital Neoplasms | 2006 |
Clonidine decreases stress response in patients undergoing carotid endarterectomy under regional anesthesia: a prospective, randomized, double-blinded, placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Conduction; Blood Pressure; Catecholamines; Clonidine; Dexmedetomidine; Double-Blind Method; Endarterectomy, Carotid; Female; Heart Rate; Humans; Hydrocortisone; Male; Middle Aged; Stress, Psychological | 2006 |
Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children.
Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Anxiety; Blood Pressure; Carbon Dioxide; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Oxygen; Pain Measurement; Pain, Postoperative; Postoperative Complications; Preanesthetic Medication; Prospective Studies; Psychiatric Status Rating Scales | 2007 |
Induced hypotension in orthognathic surgery: a comparative study of 2 pharmacological protocols.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Clonidine; Dexmedetomidine; Female; Heart Rate; Humans; Hypotension, Controlled; Isoflurane; Male; Oral Surgical Procedures; Piperidines; Remifentanil | 2008 |
Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children.
Topics: Abdomen; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthesia, Inhalation; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infant; Male; Pain Measurement; Pain, Postoperative | 2009 |
The analgesic effect of intrathecal dexmedetomidine or clonidine, with bupivacaine, in trauma patients undergoing lower limb surgery: a randomised, double-blind study.
Topics: Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Clonidine; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Lower Extremity; Male; Middle Aged; Nerve Block; Pain, Postoperative; Severity of Illness Index; Time Factors; Wounds and Injuries; Young Adult | 2013 |
Comparing the effects of oral clonidine premedication with intraoperative dexmedetomidine infusion on anesthetic requirement and recovery from anesthesia in patients undergoing major spine surgery.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthesia; Anesthesia Recovery Period; Anesthetics; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Intraoperative Care; Male; Middle Aged; Neurosurgical Procedures; Preoperative Care; Spine; Treatment Outcome | 2014 |
A Randomised Controlled Trial to Evaluate the Effectiveness of Intrathecal Bupivacaine Combined with Different Adjuvants (Fentanyl, Clonidine and Dexmedetomidine) in Caesarean Section.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Humans; Infant, Newborn; Injections, Spinal; Pain, Postoperative; Pregnancy; Young Adult | 2015 |
Comparison of Intranasal Dexmedetomidine with Intranasal Clonidine as a Premedication in Surgery.
Topics: Child; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Premedication; Surgical Procedures, Operative | 2016 |
Comparision of clonidine and dexmedetomidine for attenuation of laryngoscopy and intubation response - A randomized controlled trial.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia, General; Blood Pressure; Bradycardia; Clonidine; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Young Adult | 2016 |
Postoperative analgesia with dexmedetomidine in interscalene block. Comparative study.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Amides; Analgesia; Analgesics; Anesthetics, Local; Arthroscopy; Clonidine; Dexmedetomidine; Drug Synergism; Electric Stimulation; Female; Hemodynamics; Humans; Male; Middle Aged; Motor Activity; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine; Sensation; Shoulder; Single-Blind Method; Ultrasonography, Interventional; Young Adult | 2017 |
A Randomized Controlled Trial to Compare the Efficacy of Intravenous Dexmedetomidine and Clonidine as Adjuvants to Low Dose Opioid in Attenuation of Hemodynamic Response to Laryngoscopy and Tracheal Intubation.
Topics: Analgesics, Opioid; Clonidine; Dexmedetomidine; Fentanyl; Hemodynamics; Humans; Hypnotics and Sedatives; India; Intubation, Intratracheal; Laryngoscopy | 2018 |
Randomized clinical trial to compare the efficacy to improve the quality of surgical field of hypotensive anesthesia with clonidine or dexmedetomidine during functional endoscopic sinus surgery.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Blood Loss, Surgical; Chronic Disease; Clonidine; Dexmedetomidine; Endoscopy; Female; Hemodynamics; Humans; Male; Middle Aged; Nasal Polyps; Operative Time; Paranasal Sinuses; Rhinitis; Sinusitis; Treatment Outcome | 2019 |
A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting.
Topics: Aged; Clonidine; Coronary Artery Bypass; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Middle Aged | 2020 |
Dexmedetomidine versus clonidine adjuvants to levobupivacaine for ultrasound-guided transversus abdominis plane block in paediatric laparoscopic orchiopexy: Randomized, double-blind study.
Topics: Abdominal Muscles; Anesthetics, Local; Child; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Levobupivacaine; Male; Ontario; Orchiopexy; Pain, Postoperative; Pediatrics; Quality of Life; Ultrasonography, Interventional | 2021 |
Comparison of Efficacy of Dexmedetomidine and Clonidine Infusion to Produce Hypotensive Anesthesia in Patients Undergoing Orthognathic Surgery: A Randomized Controlled Trial.
Topics: Anesthesia; Clonidine; Dexmedetomidine; Double-Blind Method; Hemodynamics; Humans; Orthognathic Surgery | 2022 |
Preoperative anxiety in preschool children: A randomized clinical trial comparing midazolam, clonidine, and dexmedetomidine.
Topics: Anxiety; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Midazolam; Preanesthetic Medication | 2021 |
Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Clonidine; Cognitive Dysfunction; Delirium; Dexmedetomidine; Double-Blind Method; Frailty; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 2022 |
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution | 2022 |
Postoperative recovery in preschool-aged children: A secondary analysis of a randomized controlled trial comparing premedication with midazolam, clonidine, and dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives; Midazolam; Pain; Premedication | 2023 |
68 other study(ies) available for clonidine and dexmedetomidine
| Article | Year |
|---|---|
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cyclic AMP; Genetic Vectors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Protein Binding; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Proteins | 1998 |
Subtype-specific stimulation of [35S]GTPgammaS binding by recombinant alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Adrenergic, alpha-2; Sulfur Radioisotopes | 1998 |
Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions.
Topics: Adrenergic alpha-Agonists; Allosteric Regulation; Animals; Binding, Competitive; Cations, Monovalent; Guanylyl Imidodiphosphate; Humans; Idazoxan; Mammary Neoplasms, Animal; Mice; Norepinephrine; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Sodium; Tumor Cells, Cultured | 1998 |
alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Cell Line; Imidazoles; In Vitro Techniques; Mice; Rats; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Thiophenes | 2000 |
Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Binding, Competitive; Cell Line; Humans; Imidazoles; Ligands; Mice; Pain Measurement; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Thiophenes | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the α(2)-adrenoceptor compared to the imidazoline I(1) receptor.
Topics: Animals; Imidazoline Receptors; Indazoles; Ligands; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2 | 2011 |
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.
Topics: Adrenergic alpha-Agonists; Antibiotics, Antineoplastic; Apoptosis; Doxorubicin; Drug Synergism; Humans; K562 Cells; Ligands; Molecular Structure; Oxazoles; Receptors, Adrenergic, alpha-2; Rilmenidine | 2016 |
Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometry.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Binding, Competitive; Biosensing Techniques; Brimonidine Tartrate; CHO Cells; Cholera Toxin; Clonidine; Cricetinae; Dexmedetomidine; Egtazic Acid; Humans; Hydrogen-Ion Concentration; Norepinephrine; Pertussis Toxin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Antinociception by epidural and systemic alpha(2)-adrenoceptor agonists and their binding affinity in rat spinal cord and brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Algorithms; Analgesia, Epidural; Analgesics, Opioid; Animals; Brain; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Injections, Intramuscular; Male; Morphine; Neurons; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 2000 |
Synergistic interactions between two alpha(2)-adrenoceptor agonists, dexmedetomidine and ST-91, in two substrains of Sprague-Dawley rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Male; Motor Activity; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Species Specificity | 2000 |
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Veins; Cerebrovascular Circulation; Clonidine; Dexmedetomidine; Hemodynamics; Hypercapnia; Hypoxia; Injections, Spinal; Pentobarbital; Rabbits; Vasodilation; Yohimbine | 2000 |
The mechanical antihyperalgesic effect of intrathecally administered MPV-2426, a novel alpha2 -adrenoceptor agonist, in a rat model of postoperative pain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Indans; Injections, Spinal; Male; Motor Activity; Pain Measurement; Pain, Postoperative; Physical Stimulation; Postural Balance; Rats; Rats, Wistar; Time Factors | 2000 |
S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Body Temperature; CHO Cells; Clonidine; Cricetinae; Dexmedetomidine; Humans; Imidazoles; Imidazoline Receptors; Male; Mice; Oxazoles; Rats; Rats, Wistar; Receptors, Drug | 2000 |
S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Biogenic Monoamines; Clonidine; Dexmedetomidine; Imidazoles; Locus Coeruleus; Male; Mice; Motor Activity; Oxazoles; Raphe Nuclei; Rats; Rats, Wistar; Ventral Tegmental Area; Vocalization, Animal | 2000 |
Effects of alpha(2)-adrenoceptor agonists on perinatal excitotoxic brain injury: comparison of clonidine and dexmedetomidine.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Agonists; Animals; Animals, Newborn; Brain; Clonidine; Dexmedetomidine; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Mice; N-Methylaspartate; Neuroprotective Agents; Pregnancy | 2002 |
Dual alpha(2)-adrenergic agonist and alpha(1)-adrenergic antagonist actions of dexmedetomidine on human isolated endothelium-denuded gastroepiploic arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Clonidine; Dexmedetomidine; Drug Interactions; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Regional Blood Flow; Stomach | 2002 |
Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dexmedetomidine; Epinephrine; Heterozygote; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Receptors, Adrenergic, alpha-2 | 2002 |
Clonidine and dexmedetomidine potently inhibit peristalsis in the Guinea pig ileum in vitro.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dexmedetomidine; Female; Guinea Pigs; Ileum; Male; Peristalsis | 2002 |
Effects of intrathecally administered dexmedetomidine, MPV-2426 and tizanidine on EMG in rats.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Electromyography; Hypnotics and Sedatives; Imidazoles; Indans; Injections, Spinal; Motor Activity; Muscle, Skeletal; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley | 2003 |
Dexmedetomidine in pediatrics: controlled studies needed.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Child; Child Behavior; Child, Preschool; Clonidine; Dexmedetomidine; Drug Approval; Humans; Infant; Pain, Postoperative | 2004 |
Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Dexmedetomidine; Endocytosis; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha-2 | 2004 |
The in vitro effects of clonidine and dexmedetomidine on human myometrium.
Topics: Clonidine; Dexmedetomidine; Female; Humans; In Vitro Techniques; Myometrium; Pregnancy; Uterine Contraction | 2005 |
Dexmedetomidine in the treatment of cyclic vomiting syndrome.
Topics: Adrenergic alpha-Agonists; Bradycardia; Child; Clonidine; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Midazolam; Periodicity; Respiration; Syndrome; Vomiting | 2005 |
Lack in effects of therapeutic concentrations of dexmedetomidine and clonidine on the neuromuscular blocking action of rocuronium in isolated rat diaphragms.
Topics: Androstanols; Animals; Clonidine; Dexmedetomidine; Diaphragm; Dose-Response Relationship, Drug; Drug Synergism; Male; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Rats; Rats, Wistar; Rocuronium | 2007 |
Effects of alpha2-adrenoceptor agonists on tetrodotoxin-resistant Na+ channels in rat dorsal root ganglion neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Resistance; Ganglia, Spinal; Lidocaine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Yohimbine | 2007 |
Autonomic dysfunction in tetanus - what lessons can be learnt with specific reference to alpha-2 agonists?
Topics: Adrenergic alpha-Agonists; Autonomic Nervous System Diseases; Clonidine; Dexmedetomidine; Epinephrine; Female; Humans; Middle Aged; Norepinephrine; Tetanus | 2007 |
Inhibitory effects of the alpha-2 adrenergic agonists clonidine and dexmedetomidine on enhanced airway tone in ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Airway Obstruction; Animals; Bronchial Hyperreactivity; Carbachol; Clonidine; Dexmedetomidine; Guinea Pigs; Hypnotics and Sedatives; Lung; Male; Muscle, Smooth; Ovalbumin; Specific Pathogen-Free Organisms; Trachea | 2008 |
alpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice.
Topics: Adrenergic alpha-Agonists; Animals; Cell Line; Clonidine; Contrast Media; Dexmedetomidine; Iohexol; Kidney Diseases; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Renal Circulation | 2008 |
Alpha2-adrenoceptor action on cell proliferation and mammary tumour growth in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line, Tumor; Cell Proliferation; Clonidine; Dexmedetomidine; Drug Inverse Agonism; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neurokinin-1; Substance P | 2008 |
Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord.
Topics: Analgesics; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain Measurement; Spinal Cord | 2009 |
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Catheterization; Clonidine; Colon; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Rectum; Yohimbine | 2009 |
Re: Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Bupivacaine; Child; Clonidine; Dexmedetomidine; Humans; Pain, Postoperative | 2009 |
Pharmacological profile of intrathecal fadolmidine, a alpha2-adrenoceptor agonist, in rodent models.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Body Temperature; Brain; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Imidazoles; Indans; Injections, Spinal; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin | 2009 |
Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat.
Topics: Adrenergic alpha-Agonists; Amides; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Male; Nerve Block; Pain Management; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve | 2009 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Dexmedetomidine and clonidine induce long-lasting activation of the respiratory rhythm generator of neonatal mice: possible implication for critical care.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Clonidine; Dexmedetomidine; Mice; Respiration; Respiratory Center | 2012 |
Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents.
Topics: Abdominal Abscess; Adrenergic alpha-2 Receptor Agonists; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Bupivacaine; Clonidine; Colectomy; Delirium; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Pain, Postoperative; Postoperative Complications; Propofol; Young Adult | 2012 |
[Clonidine and dexmedetomidine's effect on the altered expressions of growth associated protein-43 mRNA in rat dorsal root ganglion during the development of chronic neuropathic pain].
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Ganglia, Spinal; GAP-43 Protein; Male; Neuralgia; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Dexmedetomidine and clonidine inhibit ventricular tachyarrhythmias in a rabbit model of acquired long QT syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Anti-Arrhythmia Agents; Clonidine; Dexmedetomidine; Disease Models, Animal; Heart Conduction System; Humans; Long QT Syndrome; Methoxamine; Pyrimidinones; Rabbits; Tachycardia | 2012 |
Two cases of acute dexmedetomidine withdrawal syndrome following prolonged infusion in the intensive care unit: Report of cases and review of the literature.
Topics: Clonidine; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Middle Aged; Substance Withdrawal Syndrome; Sympatholytics | 2013 |
Is there a place for pressure-support ventilation and high positive end-expiratory pressure combined to alpha-2 agonists early in severe diffuse acute respiratory distress syndrome?
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Combined Modality Therapy; Dexmedetomidine; Humans; Models, Biological; Positive-Pressure Respiration; Respiratory Distress Syndrome | 2013 |
Clonidine and dexmedetomidine increase the pressor response to norepinephrine in experimental sepsis: a pilot study.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arterial Pressure; Clonidine; Dexmedetomidine; Hypotension; Lipopolysaccharides; Male; Norepinephrine; Pilot Projects; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Vasoconstrictor Agents | 2013 |
α(2)-agonists to restore adrenergic vasoconstrictor responsiveness in septic shock: thinking outside of the box or fishing in the wrong pond?
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arterial Pressure; Clonidine; Dexmedetomidine; Hypotension; Male; Shock, Septic | 2013 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |
Transition from dexmedetomidine to enteral clonidine for ICU sedation: an observational pilot study.
Topics: Aged; Clonidine; Dexmedetomidine; Drug Substitution; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pilot Projects; Prospective Studies | 2015 |
Corneal Anesthesia With Site 1 Sodium Channel Blockers and Dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Local; Anesthetics, Combined; Animals; Cells, Cultured; Clonidine; Cornea; Dexmedetomidine; Male; Rats; Rats, Sprague-Dawley; Saxitoxin; Sodium Channel Blockers; Tetrodotoxin | 2015 |
Stimulation of Central α2 Receptors Attenuates Experimental Necrotizing Pancreatitis.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Glycodeoxycholic Acid; HMGB1 Protein; Humans; Inflammation Mediators; Male; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 2016 |
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Calcium; Clonidine; Dexmedetomidine; Exocytosis; Female; Hippocampus; Isoflurane; Male; Models, Animal; Neurons; Rats; Rats, Sprague-Dawley | 2016 |
Alpha-2 agonists for sedation in mechanically ventilated neurocritical care patients: a systematic review protocol.
Topics: Adrenergic alpha-2 Receptor Agonists; Brain Injuries; Clonidine; Conscious Sedation; Critical Care; Dexmedetomidine; Humans; Intensive Care Units; Respiration, Artificial; Systematic Reviews as Topic | 2016 |
Effectiveness of α
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anxiety; Child; Child, Preschool; Clonidine; Dexmedetomidine; Humans; Infant; Intensive Care Units, Pediatric; Patient Comfort; Research Design; Respiration, Artificial; Retrospective Studies; Time Factors | 2017 |
Intranasal dexmedetomidine for adrenergic crisis in familial dysautonomia.
Topics: Administration, Intranasal; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Anxiety; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Dexmedetomidine; Diazepam; Drug Resistance; Dysautonomia, Familial; Female; GABA Modulators; Heart Rate; Humans; Male; Pneumonia, Mycoplasma; Young Adult | 2017 |
Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia program.
Topics: Anesthesia, General; Anesthesia, Spinal; Body Weight; Bupivacaine; Clonidine; Dexmedetomidine; Fentanyl; Humans; Infant; Male; Retrospective Studies; Time Factors | 2018 |
Effect of clonidine on oncological outcomes after breast and lung cancer surgery.
Topics: Animals; Breast Neoplasms; Clonidine; Colonic Neoplasms; Dexmedetomidine; Humans; Lung Neoplasms; Rodentia | 2018 |
Effectivness of Clonidine in Treating Dexmedetomidine Withdrawal in a Patient with Co-Existing Psychiatric Illness: A Case Report.
Topics: Adult; Central Nervous System Agents; Clonidine; Depressive Disorder, Major; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Meningitis, Viral; Substance Withdrawal Syndrome | 2018 |
IV Clonidine in the PICU: Time for Dexmedetomidine to Share the Limelight?
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Dexmedetomidine; Hemodynamics; Intensive Care Units, Pediatric | 2018 |
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clinical Protocols; Clonidine; Dexmedetomidine; Equivalence Trials as Topic; Female; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Male; Midazolam; Morphine; Propensity Score; Respiration, Artificial; Retrospective Studies; Single-Blind Method; Time Factors | 2019 |
Induction of Non-Apoptotic Cell Death by Adrenergic Agonists in Human Oral Squamous Cell Carcinoma Cell Lines.
Topics: Adrenergic Agonists; Antineoplastic Agents; Carcinoma, Squamous Cell; Catalase; Cell Death; Cells, Cultured; Child; Clonidine; Dexmedetomidine; DNA Fragmentation; Epinephrine; Humans; Isoproterenol; Mouth Neoplasms; Phenylephrine; Superoxide Dismutase | 2019 |
Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via α-2 Adrenergic Receptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Age Factors; Animals; Behavior, Animal; Clonidine; Cognition; Cognitive Dysfunction; Dexmedetomidine; Disease Models, Animal; Exploratory Behavior; Female; Hippocampus; Male; Mice, Inbred C57BL; Morris Water Maze Test; Phosphorylation; Receptors, Adrenergic, alpha-2; Sevoflurane; tau Proteins | 2021 |
Comment on "Dexmedetomidine versus clonidine adjuvants to levobupivacaine for ultrasound-guided transversus abdominis plane block in paediatric laparoscopic orchiopexy: Randomized, double-blind study".
Topics: Abdominal Muscles; Child; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Levobupivacaine; Male; Orchiopexy; Ultrasonography, Interventional | 2021 |
How should dexmedetomidine and clonidine be prescribed in the critical care setting?
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives | 2022 |
A sequential allocation study to determine the ED
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Pain | 2022 |
Effects of opioid-free anesthesia on postoperative morphine consumption after bariatric surgery.
Topics: Analgesics, Opioid; Anesthesia; Bariatric Surgery; Clonidine; Dexmedetomidine; Humans; Morphine; Pain, Postoperative; Retrospective Studies | 2022 |
Impact of dexmedetomidine in conjunction with a weaning protocol on post-surgical opioid use in a neonatal intensive care unit.
Topics: Acetaminophen; Analgesics, Opioid; Clonidine; Dexmedetomidine; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Opioid-Related Disorders; Pain; Retrospective Studies; Weaning | 2023 |
[Alpha-2 adrenoreceptor agonists for the intensive care physician].
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives | 2023 |