clonidine has been researched along with cyclic gmp in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (57.50) | 18.7374 |
| 1990's | 10 (25.00) | 18.2507 |
| 2000's | 7 (17.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dinnendahl, V; Gumulka, SW | 1 |
| Bartmus, D; Dinnendahl, V; Gumulka, SW; Schönhöfer, PS; Stock, K | 1 |
| Hamlin, RL; Jenkins, JE; Jurin, RR; McCune, SA; Radin, MJ | 1 |
| Evinger, MJ; Meeley, MP; Regunathan, S; Reis, DJ | 1 |
| Meeley, MP; Regunathan, S; Reis, DJ | 1 |
| Schott, C; Stoclet, JC; Topouzis, S | 1 |
| Hatake, K; Hishida, S; Kakishita, E; Wakabayashi, I | 1 |
| Gerzer, R; Heim, JM; Müller, T; Wehling, M; Weil, J; Witzgall, H | 1 |
| Godfraind, T; Mennig, D; Morel, N; Wibo, M | 1 |
| Kotecha, N; Neild, TO | 1 |
| Gerzer, R; Heim, JM; Lorenz, R; Müller, T; Wehling, M; Weil, J; Witzgall, H | 1 |
| Verosky, M; Vulliemoz, Y | 1 |
| Frambach, DA; Valentine, JL; Weiter, JJ | 1 |
| Gutkowska, J; Pan, L | 1 |
| Harris, KH; MacLeod, KM | 1 |
| Diamond, J; Harris, KH; MacLeod, KM; Ng, DD | 1 |
| Jaiswal, RK; Sharma, RK | 1 |
| Cheung, DW; MacKay, MJ | 1 |
| Starke, K; Szadowska, A; Szmigielska, H; Szmigielski, A | 1 |
| Furchgott, RF; Jothianandan, D; Martin, W; Villani, GM | 1 |
| Ishii, K; Kato, R; Muraki, T | 1 |
| Quenzer, LF; Volle, RL | 2 |
| Skala, JP | 1 |
| Bigaud, M; Miller, RC; Schoeffter, P; Stoclet, JC | 1 |
| Heding, L; Hökfelt, B; Malmquist, J; Manhem, P | 1 |
| Grignon, L; Haidamous, M; Kouyoumdjian, JC; Lacombe, C; Lautie, JP | 1 |
| Krystal, JH; Redmond, DE | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Dinh-Xuan, AT; Higenbottam, TW; Kealey, T; Pepke-Zaba, J; Ridden, C | 1 |
| Eisenach, JC; Hood, DD; Mallak, KA; Tong, C | 1 |
| Shen, H; Virag, L; Vulliemoz, Y | 1 |
| Gutkowska, J; Mukaddam-Daher, S; Tremblay, J | 1 |
| Castro Resende, AC; Leão, MC; Lima, AF; Mesquita Ferreira, AG; Moreira, CF; Nunes, FR; Sena, KM; Silveira, SS; Soares de Moura, RS | 1 |
| Adler-Graschinsky, E; Boric, MP; Figueroa, XF; Huidobro-Toro, JP; Mendizábal, VE; Poblete, MI | 1 |
| de Castro Resende, A; de Moura, RS; de Oliveira, LF; Mendes Ribeiro, AC; Nascimento, AB; Neto, ML; Rios, AA; Santos, EJ; Tano, T | 1 |
| El-Ayoubi, R; Gutkowska, J; Menaouar, A; Mukaddam-Daher, S | 1 |
| Ge, YX; Hu, NW; Liu, XG; Xin, WJ; Xu, JT; Zhang, T | 1 |
| Brandão, RM; Carvalho, LC; Costa, CA; Pimentel, AM; Rangel, BM; Resende, AC; Soares de Moura, R; Tano, T | 1 |
| An, TH; Huang, LJ; Kim, CM; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
2 review(s) available for clonidine and cyclic gmp
| Article | Year |
|---|---|
Mechanisms of hormonal regulations in brown adipose tissue of developing rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Animals, Newborn; Body Temperature Regulation; Clonidine; Cold Temperature; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Norepinephrine; Phosphoprotein Phosphatases; Protein Kinases; Rats; Receptors, Adrenergic; Yohimbine | 1984 |
Multiple mechanisms of withdrawal from opioid drugs.
Topics: Acetylcholine; Adenine Nucleotides; Animals; Benzodiazepines; Calcium; Calmodulin; Clonidine; Conditioning, Psychological; Cyclic GMP; Dopamine; Drug Tolerance; Enkephalins; Fear; gamma-Aminobutyric Acid; Humans; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Norepinephrine; Protein Conformation; Receptors, Opioid; Serotonin; Substance Withdrawal Syndrome | 1984 |
1 trial(s) available for clonidine and cyclic gmp
| Article | Year |
|---|---|
Interaction between intrathecal neostigmine and epidural clonidine in human volunteers.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Blood Pressure; Cholinesterase Inhibitors; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Humans; Injections, Epidural; Injections, Spinal; Nausea; Neostigmine; Nitric Oxide Synthase; Norepinephrine; Pain Measurement; Stimulation, Chemical | 1996 |
37 other study(ies) available for clonidine and cyclic gmp
| Article | Year |
|---|---|
Stress-induced alterations of cyclic nucleotide levels in brain: effects of centrally acting drugs.
Topics: Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Chlorpromazine; Clonidine; Cyclic AMP; Cyclic GMP; Diazepam; Diphenhydramine; Haloperidol; Indomethacin; Male; Mice; Pentobarbital; Phentolamine; Propanolamines; Propranolol; Reserpine; Stress, Physiological | 1977 |
On the mode of action of clonidine: relationship between effects on behaviour and cyclic nucleotide content in mouse brain.
Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Brain Chemistry; Clonidine; Cyclic GMP; Exophthalmos; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Piloerection; Reserpine; Scopolamine; Time Factors | 1977 |
Effects of enalapril and clonidine on glomerular structure, function, and atrial natriuretic peptide receptors in SHHF/Mcc-cp rats.
Topics: Animals; Atrial Natriuretic Factor; Binding Sites; Clonidine; Cyclic GMP; Enalapril; Hypertension; Hypertrophy; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1992 |
Effects of clonidine and other imidazole-receptor binding agents on second messenger systems and calcium influx in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Inositol Phosphates; Receptors, Drug; Second Messenger Systems; Signal Transduction | 1991 |
Effect of clonidine on second messenger systems in rat adrenal gland.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Glands; Animals; Carbachol; Clonidine; Cyclic AMP; Cyclic GMP; Phosphatidylinositols; Rats; Second Messenger Systems | 1990 |
Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Arginine; Azepines; Clonidine; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred Strains | 1991 |
Influence of the endothelium on vascular responses of aortae from endotoxic rats.
Topics: Acetylcholine; Animals; Aorta; Clonidine; Cyclic GMP; Endothelium, Vascular; Endotoxins; Injections, Intraperitoneal; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Strains | 1990 |
Effects of clonidine and dihydralazine on plasma ANF and cyclic GMP levels in humans during volume loading.
Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Cyclic GMP; Dihydralazine; Heart Rate; Hematocrit; Humans; Hydralazine; Infusions, Intravenous; Isotonic Solutions; Male; Potassium; Sodium; Sodium Chloride | 1987 |
Effect of endothelin-1 on calcium channel gating by agonists in vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channels; Calcium Radioisotopes; Clonidine; Cyclic AMP; Cyclic GMP; Endothelins; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Peptides; Potassium Chloride; Rats; Rats, Inbred Strains | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Effects of clonidine and dihydralazine on atrial natriuretic factor and cGMP in humans.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Clonidine; Cyclic GMP; Dihydralazine; Diuresis; Hemodynamics; Humans; Hydralazine; Male; Natriuresis; Renin | 1989 |
Effect of clonidine on myocardial cyclic GMP content in the mouse-activation of central and peripheral alpha adrenoceptors.
Topics: Animals; Brain; Clonidine; Cyclic GMP; Hexamethonium; Hexamethonium Compounds; Male; Mice; Myocardium; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1989 |
Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Conductivity; Epinephrine; Isoproterenol; Phenylephrine; Pigment Epithelium of Eye; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Is clonidine-induced diuresis mediated by atrial natriuretic factor?
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cerebral Ventricles; Clonidine; Cyclic GMP; Diuresis; Injections, Intraventricular; Kinetics; Rats; Rats, Inbred Strains; Sodium | 1988 |
Influence of the endothelium on contractile responses of arteries from diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteries; Clonidine; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Rats; Rats, Inbred Strains | 1988 |
Evidence that cGMP is the mediator of endothelium-dependent inhibition of contractile responses of rat arteries to alpha-adrenoceptor stimulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Aminoquinolines; Animals; Aorta; Clonidine; Cyclic GMP; Endothelium; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains; Vasodilator Agents | 1987 |
Inhibition of alpha 2-adrenergic receptor-mediated cyclic GMP formation by a phorbol ester, a protein kinase C activator.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Cortex Neoplasms; Animals; Carcinoma; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
The effects of sodium nitroprusside and 8-bromo-cyclic GMP on electrical and mechanical activities of the rat tail artery.
Topics: Animals; Arteries; Clonidine; Cyclic GMP; Electrophysiology; Ferricyanides; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Tail | 1985 |
Changed sensitivity of alpha 2-adrenoceptors mediating a decrease in protein kinase inhibitor activity in the brain of vasopressin-hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Carrier Proteins; Clonidine; Cyclic GMP; Hydroxydopamines; Hypertension; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lypressin; Norepinephrine; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha | 1986 |
Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Aorta; Clonidine; Cyclic GMP; Dibenzylchlorethamine; Endothelium; Hemoglobins; In Vitro Techniques; Male; Nitric Oxide; Norepinephrine; Phenylephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Vasoconstriction; Vasodilator Agents | 1986 |
Effects of clonidine and yohimbine on plasma cyclic nucleotide levels in clonidine-naive and clonidine-treated mice.
Topics: Animals; Clonidine; Cyclic AMP; Cyclic GMP; Hexamethonium Compounds; Injections, Intraperitoneal; Male; Mice; Oxymetazoline; Propranolol; Time Factors; Yohimbine | 1986 |
Regulation of cyclic GMP levels in nerve tissue.
Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Clonidine; Cyclic GMP; Electric Stimulation; Ganglia; Neurons; Nitroprusside; Phosphatidylinositols; Pineal Gland; Rats | 1983 |
Dissociation between endothelium-mediated increases in tissue cGMP levels and modulation of aortic contractile responses.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Cyclic GMP; Endothelium; Female; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains | 1984 |
On the relationship between autoinhibition of norepinephrine release and cyclic GMP metabolism in rat pineal glands.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bethanechol Compounds; Clonidine; Cyclic GMP; In Vitro Techniques; Male; Nitroprusside; Norepinephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1983 |
Plasma cyclic nucleotides and plasma catecholamines before and after prolonged treatment with clonidine in hypertensive patients.
Topics: Adult; Catecholamines; Clonidine; Cyclic AMP; Cyclic GMP; Female; Glucagon; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Posture; Time Factors | 1981 |
Clonidine effect on hepatic cGMP levels in vivo could be mediated by alpha 1-adrenoceptors.
Topics: Animals; Clonidine; Cyclic GMP; Guanethidine; Liver; Male; Mice; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Histamine H3-receptor-induced inhibition of duodenal cholinergic transmission is independent of intracellular cyclic AMP and GMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Duodenum; Guinea Pigs; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine H3; Signal Transduction; Synaptic Transmission | 1993 |
Alpha-adrenoceptor stimulation of porcine pulmonary arteries.
Topics: Acetylcholine; Animals; Clonidine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Methoxamine; Phenylephrine; Pulmonary Artery; Radioimmunoassay; Receptors, Adrenergic, alpha; Swine; Vasoconstriction | 1993 |
Alpha-2 adrenoceptor agonists decrease cyclic guanosine 3',5'-monophosphate in the mouse brain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Clonidine; Cyclic GMP; Imidazoles; Male; Medetomidine; Mice; NG-Nitroarginine Methyl Ester | 1996 |
The peripheral action of clonidine analog ST-91: involvement of atrial natriuretic factor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Clonidine; Cyclic GMP; Female; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium | 1997 |
Actions of L-NAME and methylene blue on the hypotensive effects of clonidine and rilmenidine in the anesthetized rat.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxazoles; Rats; Rats, Wistar; Rilmenidine | 2000 |
Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha(2)-adrenoceptor activation.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Oxadiazoles; Oxidopamine; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Saponins; Sildenafil Citrate; Solubility; Sulfones; Sympatholytics; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Yohimbine | 2001 |
Role of the NO-cGMP pathway in the systemic antinociceptive effect of clonidine in rats and mice.
Topics: Analgesics; Animals; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mice; Nitric Oxide; Pain Measurement; Rats; Rats, Wistar; Signal Transduction | 2004 |
Urinary responses to acute moxonidine are inhibited by natriuretic peptide receptor antagonist.
Topics: Animals; Antihypertensive Agents; Benzofurans; Clonidine; Cyclic GMP; Diuresis; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Natriuresis; Natriuretic Peptides; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2005 |
Clonidine depresses LTP of C-fiber evoked field potentials in spinal dorsal horn via NO-cGMP pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Somatosensory; Hyperalgesia; Long-Term Potentiation; Male; Muscarinic Antagonists; Nerve Fibers, Unmyelinated; Neural Inhibition; Nitric Oxide; Nociceptors; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Nerve Roots; Synaptic Transmission | 2006 |
The role of NO-cGMP pathway and potassium channels on the relaxation induced by clonidine in the rat mesenteric arterial bed.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Factors; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasodilation; Vasodilator Agents | 2007 |
Synergistic antinociception of intrathecal sildenafil with clonidine in the rat formalin test.
Topics: Analgesics; Animals; Behavior, Animal; Clonidine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Guanylate Cyclase; Injections, Spinal; Male; Pain; Pain Measurement; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sildenafil Citrate; Sulfones | 2009 |