clonidine and corticosterone

clonidine has been researched along with corticosterone in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (28.44)	18.7374
1990's	22 (20.18)	18.2507
2000's	17 (15.60)	29.6817
2010's	34 (31.19)	24.3611
2020's	5 (4.59)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Good, AC; Peterson, SJ; Richards, WG	1
Giacomini, KM; Schaner, ME; Zhang, L	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M	1
Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M	1
Akamatsu, M	1
Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E	1
Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R	1
Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E	1
Kong, LY; Lan, JS; Li, SY; Pan, LF; Wang, XB; Xie, SS	1
Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW	1
Jiang, N; Kong, LY; Lan, JS; Li, ZR; Wang, KD; Wang, X; Xie, SS; Yu, W	1
Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E	1
Jiang, N; Kong, LY; Lan, JS; Li, F; Wang, J; Wang, X; Wang, ZM; Wu, JJ; Xie, SS	1
Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E	1
Kong, LY; Li, F; Li, XM; Wang, J; Wang, XB; Wang, ZM; Wu, JJ	1
Cai, P; Kong, LY; Liu, QH; Wang, XB; Wang, ZM; Wu, JJ; Xu, DQ; Yang, XL	1
Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW	1
Cai, P; Kong, L; Liu, Q; Wang, KDG; Wang, X; Wang, Z; Wu, J; Yang, X	1
Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL	1
Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M	1
Cai, P; Kong, LY; Li, F; Liu, QH; Wang, J; Wang, XB; Wu, JJ; Yang, XL	1
Cai, P; Kong, LY; Li, F; Liu, QH; Wang, J; Wang, XB; Wu, JJ; Yang, HL; Yang, XL	1
Cai, P; Kong, LY; Li, F; Wang, J; Wang, XB; Wu, JJ; Yang, XL	1
Cai, P; Fang, SQ; Kong, LY; Liu, QH; Tang, YW; Wang, C; Wang, XB; Yang, HL; Yang, XL	1
Dong, SN; Gong, Q; Li, J; Li, XK; Liu, WW; Mao, F; Tang, Y; Wang, H; Wang, TD; Xu, YX; Zhang, HY; Zhu, J	1
Huang, Q; Jiang, N; Li, Q; Liang, N; Liu, J; Xie, SS	1
Gong, Q; Li, J; Li, X; Liu, W; Mao, F; Qiu, X; Wang, H; Wang, W; Xu, Y; Zhang, H; Zhang, J; Zhu, J	1
Cai, P; Kong, LY; Liu, QH; Shi, CJ; Tang, YW; Wang, XB; Yang, HL; Yang, XL	1
Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S	1
Huang, M; Jiang, N; Kong, LY; Lan, JS; Wang, XB; Yin, FC	1
Ji, L; Kong, L; Li, S; Liu, X; Lu, D; Luo, H; Peng, W; Qu, L; Wang, C; Wang, X; Yin, F	1
Chen, L; Lei, Z; Sun, J; Sun, X; Wang, Y; Yue, S	1
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S	1
Endo, T; Starke, K; Taube, HD	1
Jezová-Repceková, D; Kulifajová, A; Vigas, M	1
Bravo, EL; Dustan, HP; Tarazi, RC	1
Gunion, MW; Hoyt, MA; Miller, S; Rosenthal, MJ; Yonzon, DB	1
Grealy, M; O'Donnell, JM	2
Kawano, K; Koike, K; Takayanagi, I	1
Marshall, IG; Prior, C; Wannan, G	1
Caffrey, JL; Carter, GC; Hathorne, LF; Sinclair, RJ	1
Bugajski, J; Gadek-Michalska, A; Połczyńska-Konior, G; Turoń, M	1
Freeman, GB; Thurmond, JB	1
Antelman, SM; Edwards, DJ; Knopf, S; Kocan, D	1
Daniels, WM; Jaffer, A; Russell, VA; Searson, A; Taljaard, JJ	1
Berridge, CW; Dunn, AJ	1
Bialik, RJ; Roberts, DC; Sardelis, M; Smythe, JW	1
Bradshaw, JE; Gleeson, RM; Grunstein, HS; Nicholson, MV; Smythe, GA	1
Chandra, A; Diliberto, EJ; Dixon, WR; Holaday, JW; Lewis, JW; Long, JB; Tortella, FC; Unsworth, CD; Viveros, OH; Way, EL	1
Neal, BS; Sparber, SB	1
Jhanwar-Uniyal, M; Leibowitz, SF; Roland, CR	1
Jhanwar-Uniyal, M; Leibowitz, SF	1
Lane, LA; McGivern, RF; Noble, EP; Poland, RE	1
Ignar, DM; Kuhn, CM	1
Manev, H; Pericić, D	1
Erwin, VG; Zgombick, JM	1
Lakić, N; Manev, H; Pericić, D	1
Bhakthavatsalam, P; Leibowitz, SF	1
Gayk, W; Merker, R; Montel, H; Starke, K	1
Iversen, LL; Salt, PJ	1
Poyser, RH; Shorter, JH; Whiting, RL	1
Salt, PJ	1
Bugajski, J; Zacny, E	1
Drew, GM; Sullivan, AT	1
Bugajski, J; Gadek, A	1
Grahame-Smith, DG; Steiner, JA	2
Eisenberg, RM	1
Pirke, KM; Spyra, B	1
Gonzalvez, ML; Marín, MT; Martinez-Piñero, MG; Milanés, MV; Vargas, ML	1
Borycz, J; Bugajski, J; Gadek-Michalska, A; Wieczorek, E	1
Anglade, G; Faudon, M; Grino, M; Paulmyer-Lacroix, O; Renard, M	1
Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A	2
Borycz, J; Bugajski, J; Gadek-Michalska, A	1
Hermans, RH; Longo, LD	1
Daniels, WM; Jaffer, A; Russell, VA; Taljaard, JJ	1
Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A; Głód, R	2
Borycz, J; Bugajski, J; Gadek-Michalska, A; Głód, R; Ołowska, A	1
Flores, LE; Francini, F; Gagliardino, JJ	1
Calhau, C; Gründemann, D; Martel, F; Schömig, E	1
Bugajski, AJ; Bugajski, J; Gadek-Michalska, A; Głód, R	2
Dygalo, NN; Kalinina, TS; Kobzev, VF; Saharov, DG; Shishkina, GT; Sournina, NY	1
Barna, I; Gyires, K; Müllner, K; Palkovits, M; Reichart, A; Rónai, AZ	1
Baumann, MH; Milchanowski, AB; Rothman, RB	1
Buijs, RM; Kalsbeek, A; La Fleur, S; Van Heijningen, C	1
Clark, KA; Mohankumar, PS; Mohankumar, SM; Shin, AC; Sirivelu, MP	1
Milot, MR; Plamondon, H	1
Muck-Šeler, D; Pivac, N; Švob Štrac, D	1
Cline, MA; Khan, MSI; Ogino, M; Tachibana, T	1
Jung, JS; Kim, SS; Lee, JR; Lim, SM; Park, SH; Sharma, N; Suh, HW	1
Diez-Alarcia, R; Horrillo, I; Meana, JJ; Ortega, JE; Urigüen, L	1
Fernandes, MF; Fuller, B; Horman, T; Leri, F; Tigert, M; Zhou, Y	1
Clark, KA; Jacob, EB; MohanKumar, PS; MohanKumar, SMJ	1
Brakenridge, SC; Efron, PA; Kannan, KB; Loftus, TJ; Mira, JC; Mohr, AM	1

Other Studies

109 other study(ies) available for clonidine and corticosterone

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods. Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20 Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship	1993
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection	1998
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease. Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine	2009
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds. Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease. Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding	2009
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies. European journal of medicinal chemistry, 2014, Feb-12, Volume: 73 Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding	2014
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies	2014
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins	2014
Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease. Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Carbolines; Cell Line; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Electrophorus; Horses; Humans; Molecular Docking Simulation; Protein Aggregation, Pathological; Tacrine	2014
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23 Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship	2014
Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease. European journal of medicinal chemistry, 2015, May-05, Volume: 95 Topics: Acetylcholinesterase; Alzheimer Disease; Benzopyrans; Blood-Brain Barrier; Brain; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Coumarins; Drug Design; Erythrocytes; Humans; Kinetics; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Piperazines; Tacrine	2015
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2015
Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease. Bioorganic & medicinal chemistry, 2016, Apr-01, Volume: 24, Issue:7 Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Cholinesterases; Coumarins; Donepezil; Dose-Response Relationship, Drug; Drug Design; Eels; Humans; Indans; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Piperidines; Structure-Activity Relationship	2016
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors. Bioorganic & medicinal chemistry, 2016, 10-15, Volume: 24, Issue:20 Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship	2016
Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin. Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Donepezil; Electrophorus; Horses; Humans; Indans; Indoles; Iron; Kinetics; Melatonin; Molecular Docking Simulation; Peptide Fragments; Piperidines; Protein Multimerization; Rats; Zinc	2016
Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease. European journal of medicinal chemistry, 2016, Nov-10, Volume: 123 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Copper; Donepezil; Drug Design; Humans; Indans; Kinetics; Liver; Mice; Models, Molecular; Peptide Fragments; Piperidines; Protein Aggregates; Protein Conformation	2016
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21 Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2016
Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease. Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22 Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Parkinson Disease; Rats; Small Molecule Libraries; Structure-Activity Relationship	2016
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment. European journal of medicinal chemistry, 2017, Apr-21, Volume: 130 Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species	2017
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia. European journal of medicinal chemistry, 2017, Apr-21, Volume: 130 Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques	2017
Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease. Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Binding Sites; Blood-Brain Barrier; Chromones; Copper; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; Structure-Activity Relationship	2017
Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-β aggregation for the treatment of Alzheimer's disease. European journal of medicinal chemistry, 2017, Sep-29, Volume: 138 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Mice; Mice, Inbred Strains; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; PC12 Cells; Protein Aggregates; Rats; Structure-Activity Relationship	2017
Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease. European journal of medicinal chemistry, 2017, Oct-20, Volume: 139 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzylamines; Blood-Retinal Barrier; Butyrylcholinesterase; Cell Death; Cholinergic Agents; Cholinesterase Inhibitors; Cinnamates; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Structure-Activity Relationship	2017
Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease. Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrogen Peroxide; Imines; Ligands; Lipopolysaccharides; Mice; Microglia; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; PC12 Cells; Peptide Fragments; Protein Aggregates; Rats; Salicylates; Structure-Activity Relationship	2017
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imidazoles; Mice; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Propylamines; Pyrimidines; Rats; Scopolamine; Structure-Activity Relationship; Thiourea	2018
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease. European journal of medicinal chemistry, 2018, Feb-25, Volume: 146 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Aggregates; Range of Motion, Articular; Structure-Activity Relationship; Thiocarbamates	2018
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment. Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Depression; Drug Design; Ligands; Mice; Permeability; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship; Tacrine; Vilazodone Hydrochloride	2018
Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease. European journal of medicinal chemistry, 2019, Feb-01, Volume: 163 Topics: Alzheimer Disease; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Dimerization; Humans; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Prenylation; Rats; Resveratrol; Structure-Activity Relationship	2019
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors. European journal of medicinal chemistry, 2019, Oct-15, Volume: 180 Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine	2019
Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease. RSC medicinal chemistry, 2020, Feb-01, Volume: 11, Issue:2 Topics:	2020
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease. European journal of medicinal chemistry, 2021, Jul-05, Volume: 219 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Azoles; Binding Sites; Blood-Brain Barrier; Cyclic S-Oxides; Drug Design; Humans; Interleukin-6; Isoindoles; Ligands; Mitochondria; Molecular Docking Simulation; Neuroprotective Agents; NF-E2-Related Factor 2; Organoselenium Compounds; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Selenium; Signal Transduction; Thiadiazines	2021
Development of 5-hydroxyl-1-azabenzanthrone derivatives as dual binding site and selective acetylcholinesterase inhibitors. European journal of medicinal chemistry, 2022, Apr-15, Volume: 234 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Binding Sites; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Rats	2022
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease. European journal of medicinal chemistry, 2022, Jun-05, Volume: 236 Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate	2022
Pre- and postsynaptic components in effect of drugs with alpha adrenoceptor affinity. Nature, 1975, Apr-03, Volume: 254, Issue:5499 Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Corticosterone; In Vitro Techniques; Methoxamine; Muscle Contraction; Neurons; Norepinephrine; Oxymetazoline; Phenylephrine; Propranolol; Pulmonary Artery; Rabbits; Receptors, Adrenergic; Synapses	1975
Effects of phentolamine and clonidine on pituitary-adrenocortical axis during stress in conscious rats. Endocrinologia experimentalis, 1978, Volume: 12, Issue:1 Topics: Animals; Clonidine; Corticosterone; Male; Phentolamine; Pituitary-Adrenal System; Rats; Restraint, Physical; Stress, Physiological	1978
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. Circulation research, 1977, Volume: 40, Issue:5 Suppl 1 Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricted; Disease Models, Animal; Dogs; Guanethidine; Hemodynamics; Hypertension; Male; Metyrapone; Norepinephrine; Premedication; Renin	1977
Role of hypothalamic paraventricular nucleus alpha- and beta-adrenergic receptors in regulation of blood glucose, free fatty acids and corticosterone. Brain research, 1992, Aug-14, Volume: 588, Issue:1 Topics: Animals; Blood Glucose; Catecholamines; Clonidine; Corticosterone; Fatty Acids, Nonesterified; Injections, Subcutaneous; Isoproterenol; Male; Methoxamine; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stress, Psychological	1992
Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline. British journal of pharmacology, 1992, Volume: 105, Issue:4 Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Desipramine; Dihydroalprenolol; Male; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes	1992
Effects of aging on alpha 2-adrenoceptor mechanisms in isolated guinea-pig tracheal preparations. European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1 Topics: Adrenergic alpha-Agonists; Aging; Animals; Clonidine; Corticosterone; Dinoprost; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Microsomes; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prostaglandin D2; Receptors, Adrenergic, alpha; Trachea	1991
Alpha-adrenoceptor blocking properties of vesamicol. European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Vas Deferens	1991
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat. British journal of pharmacology, 1991, Volume: 102, Issue:2 Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1991
Naloxone potentiates contractile responses to epinephrine in isolated canine arteries. Circulatory shock, 1990, Volume: 31, Issue:3 Topics: Animals; Clonidine; Corticosterone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Dynorphins; Epinephrine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Norepinephrine; Peptide Fragments; Phenylephrine; Receptors, Opioid; Renal Artery	1990
Effects of systemic and intracerebroventricular phenylephrine and clonidine on corticosterone secretion in rats. Endocrinologia experimentalis, 1990, Volume: 24, Issue:1-2 Topics: Animals; Clonidine; Corticosterone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine	1990
Monoamines and effects of chlordiazepoxide on the corticosterone response to stress. Physiology & behavior, 1986, Volume: 37, Issue:6 Topics: Animals; Apomorphine; Biogenic Amines; Chlordiazepoxide; Clonidine; Corticosterone; Hydroxyindoleacetic Acid; Male; Mice; Quipazine; Stress, Physiological	1986
Persistent sensitization of clonidine-induced hypokinesia following one exposure to a stressor: possible relevance to panic disorder and its treatment. Psychopharmacology, 1989, Volume: 98, Issue:1 Topics: Animals; Clonidine; Corticosterone; Fear; Male; Methoxyhydroxyphenylglycol; Motor Activity; Norepinephrine; Panic; Pentylenetetrazole; Rats; Rats, Inbred Strains; Stress, Psychological	1989
The effect of partial noradrenergic denervation on corticosterone secretion in the rat. Neurochemical research, 1989, Volume: 14, Issue:12 Topics: Adrenergic Fibers; Animals; Benzylamines; Brain; Clonidine; Corticosterone; Isoproterenol; Male; Rats; Rats, Inbred Strains	1989
Restraint-stress-induced changes in exploratory behavior appear to be mediated by norepinephrine-stimulated release of CRF. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:10 Topics: Animals; Benzylamines; Biogenic Amines; Brain; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Exploratory Behavior; Male; Mice; Mice, Inbred Strains; Neurotoxins; Norepinephrine; Phenylephrine; Prazosin; Restraint, Physical; Stress, Physiological	1989
Adrenal demedullation blocks and brain norepinephrine depletion potentiates the hyperglycemic response to a variety of stressors. Brain research, 1989, Nov-13, Volume: 502, Issue:1 Topics: Adrenal Medulla; Animals; Blood Glucose; Brain; Clonidine; Corticosterone; Deoxyglucose; Electric Stimulation; Hypothalamus; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred Strains; Stress, Physiological	1989
The central vs. peripheral effects of clonidine on ACTH, corticosterone and glucose release. European journal of pharmacology, 1985, May-20, Volume: 111, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Clonidine; Corticosterone; Deoxyglucose; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains	1985
Multiple opiate receptors: functional implications. Federation proceedings, 1985, Volume: 44, Issue:13 Topics: Adrenal Medulla; Adrenalectomy; Animals; Azocines; Behavior, Animal; Binding Sites; Blood Pressure; Clonidine; Corticosterone; Enkephalins; Naloxone; Receptors, Opioid; Stress, Physiological; Sympathetic Nervous System	1985
Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: Animals; Body Temperature; Clonidine; Corticosterone; Dibenzazepines; Male; Mianserin; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Substance Withdrawal Syndrome	1986
Diurnal rhythm of alpha 2-noradrenergic receptors in the paraventricular nucleus and other brain areas: relation to circulating corticosterone and feeding behavior. Life sciences, 1986, Feb-03, Volume: 38, Issue:5 Topics: Animals; Brain; Circadian Rhythm; Clonidine; Corticosterone; Feeding Behavior; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tissue Distribution	1986
Impact of circulating corticosterone on alpha 1- and alpha 2-noradrenergic receptors in discrete brain areas. Brain research, 1986, Mar-19, Volume: 368, Issue:2 Topics: Adrenalectomy; Animals; Brain Chemistry; Clonidine; Corticosterone; Hypothalamus; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1986
Influence of prenatal ethanol exposure on hormonal responses to clonidine and naloxone in prepubescent male and female rats. Psychoneuroendocrinology, 1986, Volume: 11, Issue:1 Topics: Animals; Brain; Catecholamines; Clonidine; Corticosterone; Endorphins; Female; Fetal Alcohol Spectrum Disorders; Luteinizing Hormone; Male; Naloxone; Pregnancy; Rats; Rats, Inbred Strains; Sex Factors; Synaptic Transmission	1986
Relative ontogeny of opioid and catecholaminergic regulation of thyrotropin secretion in the rat. Endocrinology, 1988, Volume: 123, Issue:1 Topics: Aging; Animals; Animals, Newborn; Apomorphine; Body Temperature; Catecholamines; Clonidine; Cold Temperature; Corticosterone; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone	1988
Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats. Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:4 Topics: Animals; Anticonvulsants; Clonidine; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Stimulation, Chemical	1987
Central mechanisms of ethanol-induced adrenocortical response in selectively bred lines of mice. Neuroendocrinology, 1987, Volume: 46, Issue:4 Topics: Alcohol Deterrents; Animals; Carbachol; Clonidine; Corticosterone; Ethanol; Halothane; Male; Mice; Phentolamine; Propranolol; Yohimbine	1987
Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level. Neuroendocrinology, 1986, Volume: 43, Issue:3 Topics: Animals; Apomorphine; Atropine; Bicuculline; Clonidine; Corticosterone; Dexamethasone; Diazepam; Drug Interactions; Female; Haloperidol; Picrotoxin; Rats; Rats, Inbred Strains; Yohimbine	1986
Alpha 2-noradrenergic feeding rhythm in paraventricular nucleus: relation to corticosterone. The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 2 Topics: Adrenalectomy; Animals; Clonidine; Corticosterone; Deoxyglucose; Feeding Behavior; Injections; Injections, Intraperitoneal; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Periodicity; Rats; Rats, Inbred Strains; Time Factors	1986
Comparison of the effects of clonidine on pre- and postsynaptic adrenoceptors in the rabbit pulmonary artery. Alpha-sympathomimetic inhibition of Neurogenic vasoconstriction. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Pulmonary Artery; Rabbits; Receptors, Adrenergic; Sympathetic Nervous System; Time Factors; Tritium	1974
Catecholamine uptake sites in the rat heart after 6-hydroxydopamine treatment and in a genetically hypertensive strain. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:4 Topics: Animals; Catecholamines; Clonidine; Corticosterone; Heart; Hydroxydopamines; Hypertension; In Vitro Techniques; Male; Myocardium; Norepinephrine; Rats; Sympathectomy; Tritium	1973
Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat. British journal of pharmacology, 1974, Volume: 51, Issue:1 Topics: Animals; Antihypertensive Agents; Cats; Cellophane; Clonidine; Corticosterone; Delayed-Action Preparations; Disease Models, Animal; Guanethidine; Hydralazine; Hypertension; Ligation; Methyldopa; Pempidine	1974
Inhibition of noradrenaline uptake 2 in the isolated rat heart by steroids, clonidine and methoxylated phenylethylamines. European journal of pharmacology, 1972, Volume: 20, Issue:3 Topics: Animals; Clonidine; Coronary Vessels; Corticosterone; Depression, Chemical; Dose-Response Relationship, Drug; Estradiol; Gonadal Steroid Hormones; Guinea Pigs; Heart Rate; In Vitro Techniques; Kinetics; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Progesterone; Testosterone	1972
Effect of intracerebroventricular clonidine on serum corticosterone levels in rats. Hormone research, 1984, Volume: 20, Issue:2 Topics: Adrenocorticotropic Hormone; alpha-Methyltyrosine; Animals; Clonidine; Corticosterone; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methyltyrosines; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1984
Pharmacological characterisation of pre- and postsynaptic alpha-adrenoceptors in dog saphenous vein. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 314, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Corticosterone; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Pulmonary Artery; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Saphenous Vein; Sympathetic Nervous System; Vasoconstriction	1980
Interference of clonidine and alpha-methyl-p-tyrosine with stress and central histaminergic stimulation of the corticosterone response in rats. Agents and actions, 1984, Volume: 14, Issue:3-4 Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Brain; Clonidine; Corticosterone; Histamine; Immobilization; Male; Methyltyrosines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Stress, Physiological	1984
Central pharmacological control of corticosterone secretion in the intact rat. Demonstration of cholinergic and serotoninergic facilitatory and alpha-adrenergic inhibitory mechanisms. Psychopharmacology, 1980, Volume: 71, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Clonidine; Corticosterone; Male; Oxotremorine; Parasympathetic Nervous System; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin	1980
Influence of clonidine on the acute dependence response elicited in naive rats by naloxone. Life sciences, 1983, Apr-04, Volume: 32, Issue:14 Topics: Animals; Clonidine; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Morphine; Naloxone; Opioid-Related Disorders; Rats; Rats, Inbred Strains; Time Factors	1983
The effect of repeated electroconvulsive shock on corticosterone responses to centrally acting pharmacological stimuli in the male rat. Psychopharmacology, 1980, Volume: 71, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Central Nervous System Agents; Clonidine; Corticosterone; Electroshock; Male; Methyltyrosines; Oxotremorine; Rats; Time Factors; Vasopressins	1980
Catecholamine turnover in the brain and the regulation of luteinizing hormone and corticosterone in starved male rats. Acta endocrinologica, 1982, Volume: 100, Issue:2 Topics: Albuterol; Animals; Apomorphine; Brain; Catecholamines; Clonidine; Corticosterone; Dopamine; Hypothalamus; Levodopa; Luteinizing Hormone; Male; Median Eminence; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Starvation	1982
Effects of intracerebroventricular clonidine on the hypothalamic noradrenaline and plasma corticosterone levels of opiate naive rats and after naloxone-induced withdrawal. Brain research, 1994, Jun-06, Volume: 647, Issue:2 Topics: Animals; Clonidine; Corticosterone; Hypothalamus; Injections, Intraventricular; Male; Morphine Dependence; Naloxone; Norepinephrine; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Substance Withdrawal Syndrome	1994
Effect of crowding on corticosterone responses to central adrenergic stimulation. Agents and actions, 1994, Volume: 41 Spec No Topics: Animals; Clonidine; Corticosterone; Crowding; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Isoproterenol; Male; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic; Stress, Psychological	1994
Blockade of alpha 2-adrenoceptors stimulates basal and stress-induced adrenocorticotropin secretion in the developing rat through a central mechanism independent from corticotropin-releasing factor and arginine vasopressin. Endocrinology, 1994, Volume: 135, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Arginine Vasopressin; Brain; Catecholamines; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; In Vitro Techniques; Locus Coeruleus; Lypressin; Pituitary Gland; Rats; Rats, Sprague-Dawley; Reference Values; Stress, Physiological	1994
Calcium channel blockers impair the pituitary-adrenocortical responses to central adrenergic receptors stimulation. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Nifedipine; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Stimulation, Chemical; Verapamil	1993
Social crowding stress diminishes the pituitary-adrenocortical and hypothalamic histamine response to adrenergic stimulation. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:4 Topics: Animals; Clonidine; Corticosterone; Crowding; Histamine; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Isoproterenol; Male; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Stress, Psychological; Sympathetic Nervous System; Sympathomimetics	1993
Altered catecholaminergic behavioral and hormonal responses in rats following early postnatal hypoxia. Physiology & behavior, 1994, Volume: 55, Issue:3 Topics: Animals; Apomorphine; Arousal; Behavior, Animal; Catecholamines; Clonidine; Corticosterone; Dose-Response Relationship, Drug; Female; Fetal Hypoxia; Haloperidol; Hypothalamo-Hypophyseal System; Male; Motor Activity; Pituitary-Adrenal System; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereotyped Behavior	1994
Central histaminergic mechanisms in the corticosterone response to clonidine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:3 Topics: Animals; Brain; Clonidine; Corticosterone; Histamine; Histamine Antagonists; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Methylhistidines; Pituitary-Adrenal System; Rats; Rats, Wistar; Yohimbine	1993
Alpha 2- and beta-adrenergic stimulation of corticosterone secretion in rats. Neurochemical research, 1993, Volume: 18, Issue:2 Topics: Animals; Clonidine; Corticosterone; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine	1993
Effect of indomethacin on the pituitary-adrenocortical response to adrenergic stimulation. Life sciences, 1996, Volume: 59, Issue:14 Topics: Adrenal Cortex; Adrenergic Agents; Animals; Clonidine; Corticosterone; Cyclooxygenase Inhibitors; Epinephrine; Indomethacin; Isoproterenol; Male; Norepinephrine; Phenylephrine; Pituitary Gland; Rats; Rats, Wistar	1996
The role of prostaglandins and the hypothalamic and hippocampal histamine in the clonidine-induced pituitary-adrenocortical response. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Corticosterone; Hippocampus; Histamine; Hypothalamus; Indomethacin; Male; Pituitary-Adrenal System; Prostaglandins; Rats; Rats, Wistar	1996
Modulatory effect of hormones on insulin secretion in vitro in the toad. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 120, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Bufo arenarum; Cattle; Clonidine; Corticosterone; Dihydrotestosterone; Epinephrine; Estradiol; Estrone; Glucagon; Glucose; Hormones; Humans; Insulin; Insulin Secretion; Male; Pancreas; Prolactin; Somatostatin; Thyroxine; Triiodothyronine	1998
Blockade of nitric oxide formation impairs adrenergic-induced ACTH and corticosterone secretion. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:2 Topics: Adrenergic Agonists; Adrenocorticotropic Hormone; Animals; Clonidine; Corticosterone; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Adrenergic	1999
Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1 Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Caco-2 Cells; Carrier Proteins; Cations; Cell Line; Clonidine; Corticosterone; DNA, Recombinant; Dose-Response Relationship, Drug; Gene Expression; Histamine; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Membrane Potentials; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Plasmids; Quinolines; Quinolinium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Time Factors; Transfection; Tritium	2001
Involvement of constitutive (COX-1) and inducible cyclooxygenase (COX-2) in the adrenergic-induced ACTH and corticosterone secretion. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:4 Pt 2 Topics: Adrenocorticotropic Hormone; Animals; Clenbuterol; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Cyclooxygenase 1; Cyclooxygenase 2; Hypothalamo-Hypophyseal System; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Phenylephrine; Pituitary-Adrenal System; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Receptors, Adrenergic	2001
Effect of social stress on COX-1 and COX-2-induced alterations in the adrenergic agonists-evoked hypothalamic-pituitary-adrenal responses. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:4 Pt 2 Topics: Adrenocorticotropic Hormone; Animals; Clonidine; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Hypothalamo-Hypophyseal System; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Nitric Oxide; Nitrobenzenes; Piroxicam; Pituitary-Adrenal System; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic; Stress, Psychological; Sulfonamides	2001
Effects of antisense oligodeoxynucleotide to the alpha2A-adrenoceptors on the plasma corticosterone level and on elevated plus-maze behavior in rats. Psychoneuroendocrinology, 2002, Volume: 27, Issue:5 Topics: Adrenergic alpha-Agonists; Animals; Anxiety; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Locus Coeruleus; Male; Microinjections; Oligonucleotides, Antisense; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction	2002
Gyrus cinguli transection abolishes delta-opioid receptor-induced gastroprotection and alters alpha 2 adrenoceptor activity in the lower brainstem in rats. Brain research, 2002, Aug-23, Volume: 947, Issue:1 Topics: Adrenalectomy; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain Stem; Cisterna Magna; Clonidine; Corticosterone; Enkephalin, Leucine-2-Alanine; Ethanol; Gyrus Cinguli; Hypothalamo-Hypophyseal System; Limbic System; Male; Microinjections; Rats; Rats, Wistar; Receptors, Opioid, delta; Solvents; Stomach Ulcer	2002
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration. Neuroscience, 2004, Volume: 125, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Growth Hormone; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Synaptic Transmission	2004
Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35 Topics: Animals; Axonal Transport; Bicuculline; Blood Glucose; Circadian Rhythm; Clonidine; Corticosterone; gamma-Aminobutyric Acid; Glucagon; Gluconeogenesis; Herpesvirus 1, Suid; Hyperglycemia; Hypothalamus; Insulin; Isoproterenol; Liver; Male; Microdialysis; Muscimol; N-Methylaspartate; Norepinephrine; Parasympathectomy; Parasympathetic Nervous System; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Sympathectomy; Sympathetic Nervous System; Tetrodotoxin; Vasopressins	2004
Systemic administration of leptin decreases plasma corticosterone levels: role of hypothalamic norepinephrine. Brain research, 2008, Feb-21, Volume: 1195 Topics: Adrenergic Agents; Animals; Clonidine; Corticosterone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Injections, Intravenous; Isoproterenol; Leptin; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha	2008
Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia. Hormones and behavior, 2011, Volume: 59, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Brain; Brain Ischemia; Clonidine; Corticosterone; Hypothalamo-Hypophyseal System; Male; Maze Learning; Memory; Neurons; Norepinephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Time Factors; Yohimbine	2011
The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats. Croatian medical journal, 2012, Volume: 53, Issue:3 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Adrenocorticotropic Hormone; alpha-Methyltyrosine; Analysis of Variance; Animals; Antihypertensive Agents; Clonidine; Corticosterone; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Female; Hypnotics and Sedatives; Rats; Rats, Wistar; Reserpine; Yohimbine	2012
Acute injections of corticosterone, norepinephrine and epinephrine retards food passage in the crop of chicks. General and comparative endocrinology, 2016, Jan-01, Volume: 225 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Animals, Newborn; Chickens; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Defecation; Epinephrine; Gastric Emptying; Isoproterenol; Male; Norepinephrine; Phenylephrine; Urocortins	2016
Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states. Brain research bulletin, 2016, Volume: 124 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Clonidine; Corticosterone; Depressive Disorder; Disease Models, Animal; Down-Regulation; Drug Administration Routes; Glucose; Glucose Tolerance Test; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred ICR; Restraint, Physical; Time Factors; Up-Regulation	2016
Effect of subchronic corticosterone administration on α Psychopharmacology, 2016, Volume: 233, Issue:23-24 Topics: Animals; Anti-Inflammatory Agents; Clonidine; Corticosterone; Disease Models, Animal; Hypothalamo-Hypophyseal System; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic	2016
An exploration of the aversive properties of 2-deoxy-D-glucose in rats. Psychopharmacology, 2018, Volume: 235, Issue:10 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Behavior, Animal; Blood Glucose; Bupropion; Clonidine; Corticosterone; Deoxyglucose; Disease Models, Animal; Dopamine Uptake Inhibitors; Hypoglycemia; Locomotion; Male; Norepinephrine; Rats; Rats, Sprague-Dawley	2018
Leptin and HPA axis activity in diabetic rats: Effects of adrenergic agonists. Brain research, 2019, 03-15, Volume: 1707 Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Animals; Clonidine; Corticosterone; Diabetes Mellitus, Experimental; Hypothalamo-Hypophyseal System; Isoproterenol; Leptin; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley	2019
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress. Shock (Augusta, Ga.), 2020, Volume: 54, Issue:4 Topics: Animals; Clonidine; Corticosterone; Enzyme-Linked Immunosorbent Assay; Hematopoietic Stem Cells; Hepatocyte Growth Factor; Matrix Metalloproteinase 9; Propranolol; Proto-Oncogene Proteins c-met; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Shock, Hemorrhagic; Wounds and Injuries	2020