clonidine has been researched along with clorgyline in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (43.24) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 2 (5.41) | 29.6817 |
| 2010's | 13 (35.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Chen, X; Huang, L; Li, X; Sun, Y | 1 |
| Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xiao, G | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Yang, X; Zheng, Y | 1 |
| Ai, J; Deng, Y; Li, Y; Liu, Q; Luo, L; Qiang, X; Tan, Z; Xiao, G; Yang, X | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, X | 1 |
| Liu, W; Ma, Q; Pan, W; Sang, Z; Wang, K; Yu, L | 1 |
| Han, X; Liu, W; Ma, Q; Sang, Z; Wang, H; Wang, K; Ye, M; Yu, L | 1 |
| Dong, SN; Gong, Q; Li, J; Li, XK; Liu, WW; Mao, F; Tang, Y; Wang, H; Wang, TD; Xu, YX; Zhang, HY; Zhu, J | 1 |
| Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Xu, R; Yang, J; Zhang, X | 1 |
| Deng, Y; Li, Y; Liu, H; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, Z; Zhang, X; Zheng, Y | 1 |
| Fukuda, H; Ono, H; Tanabe, M | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Hauger, RL; Linnoila, M; Potter, WZ; Scheinin, M; Siever, LJ | 1 |
| Blier, P; de Montigny, C | 1 |
| Campbell, IC; McKernan, RM | 1 |
| Campbell, IC; McWilliam, JR | 2 |
| Lerer, B | 1 |
| Cohen, RM; Murphy, DL; Siever, LJ | 1 |
| Murphy, DL; Siever, LJ; Uhde, TW | 1 |
| Aulakh, CS; Campbell, IC; Cohen, RM; Murphy, DL | 1 |
| Cohen, RM; Daly, JW; Ebstein, RP; Murphy, DL | 1 |
| Jimerson, DC; Kafka, MS; Lake, CR; Murphy, DL; Siever, LJ; Targum, S; Uhde, TW | 1 |
| Aulakh, CS; Cohen, RM; McLellan, C; Murphy, DL | 1 |
| Enero, MA; Gutkind, JS | 1 |
| Aulakh, CS; Cohen, RM; Murphy, DL; Pradhan, SN | 1 |
| Insel, TR; Murphy, DL; Roy, BF; Siever, LJ; Uhde, TW | 1 |
| Haque, M; Kulkarni, RN; MacDermot, J; Olmos, G | 1 |
| Klemfuss, H; Kripke, DF | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Molewijk, HE; Olivier, B; van der Poel, AM | 1 |
| Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Fernández-Pastor, B; Mateo, Y; Meana, JJ | 1 |
| Baker, GB; Holt, A; Todd, KG | 1 |
1 review(s) available for clonidine and clorgyline
| Article | Year |
|---|---|
Alternative therapies for bipolar disorder.
Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid | 1985 |
36 other study(ies) available for clonidine and clorgyline
| Article | Year |
|---|---|
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine | 2013 |
Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Blood-Brain Barrier; Chelating Agents; Copper; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Protein Aggregates; Swine | 2016 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Isoflavones; Mannich Bases; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2017 |
Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Mannich Bases; Neuroprotective Agents; PC12 Cells; Rats | 2017 |
Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rivastigmine; Structure-Activity Relationship; Swine | 2017 |
DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipyrine; Benzofurans; Binding Sites; Blood-Brain Barrier; Edaravone; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Structure, Tertiary | 2017 |
Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Cholinesterase Inhibitors; Humans; Kinetics; Models, Molecular; Monoamine Oxidase Inhibitors; Thioxanthenes; Xanthones | 2017 |
Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quinolines; Swine | 2017 |
Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzophenones; Binding Sites; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Drug Design; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Neuroprotective Agents; PC12 Cells; Permeability; Phenols; Piperazines; Protein Structure, Tertiary; Rats; Structure-Activity Relationship | 2017 |
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imidazoles; Mice; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Propylamines; Pyrimidines; Rats; Scopolamine; Structure-Activity Relationship; Thiourea | 2018 |
Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Line; Cell Survival; Chalcones; Chelating Agents; Copper; Drug Design; Flurbiprofen; Humans; Lipopolysaccharides; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitric Oxide; Peptide Fragments; Recombinant Proteins; Structure-Activity Relationship | 2018 |
Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzylamines; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Permeability; Protein Aggregates; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2018 |
Spinal alpha 1- and alpha 2-adrenoceptors mediate facilitation and inhibition of spinal motor transmission, respectively.
Topics: Animals; Clonidine; Clorgyline; Levodopa; Male; Motor Neurons; Piperoxan; Prazosin; Premedication; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission | 1990 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Dissociation of norepinephrine turnover from alpha-2 responses after clorgiline.
Topics: Bipolar Disorder; Blood Pressure; Clonidine; Clorgyline; Depressive Disorder; Female; Growth Hormone; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Propylamines; Pulse; Receptors, Adrenergic, alpha | 1988 |
Serotoninergic but not noradrenergic neurons in rat central nervous system adapt to long-term treatment with monoamine oxidase inhibitors.
Topics: Animals; Clonidine; Clorgyline; Locus Coeruleus; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Phenelzine; Raphe Nuclei; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Synaptic Transmission | 1985 |
Clorgyline and desipramine alter the sensitivity of [3H]noradrenaline release to calcium but not to clonidine.
Topics: Animals; Calcium; Cerebral Cortex; Clonidine; Clorgyline; Desipramine; Drug Interactions; Male; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes | 1986 |
Effects of antidepressant drug treatments on alpha 2-adrenoceptor control of [3H]noradrenaline release from hypothalamic synaptosomes.
Topics: Animals; Antidepressive Agents; Clonidine; Clorgyline; Desipramine; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1987 |
[3H]adrenaline release from hypothalamic synaptosomes and its modulation by clonidine: effects of chronic antidepressant drug regimens.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Clonidine; Clorgyline; Desipramine; Epinephrine; Hypothalamus; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes | 1987 |
Antidepressants and alpha 2-adrenergic autoreceptor desensitization.
Topics: Blood Pressure; Clonidine; Clorgyline; Drug Interactions; Female; Humans; Imipramine; Middle Aged; Propylamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Possible subsensitization of alpha 2-adrenergic receptors by chronic monoamine oxidase inhibitor treatment in psychiatric patients.
Topics: Adult; Blood Pressure; Body Temperature Regulation; Clonidine; Clorgyline; Depressive Disorder; Double-Blind Method; Humans; Middle Aged; Norepinephrine; Propylamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Functional subsensitivity of alpha 2-adrenoceptors accompanies reductions in yohimbine binding after clorgyline treatment.
Topics: Animals; Clonidine; Clorgyline; In Vitro Techniques; Male; Motor Activity; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Chronic effects of a monoamine oxidase-inhibiting antidepressant: decreases in functional alpha-adrenergic autoreceptors precede the decrease in norepinephrine-stimulated cyclic adenosine 3': 5'-monophosphate systems in rat brain.
Topics: Animals; Brain; Clonidine; Clorgyline; Cyclic AMP; Male; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1982 |
Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment.
Topics: Clonidine; Clorgyline; Depressive Disorder; Fenfluramine; Growth Hormone; Humans; Hydrocortisone; Methoxyhydroxyphenylglycol; Norepinephrine; Prolactin; Propylamines; Receptors, Adrenergic; Receptors, Neurotransmitter; Receptors, Serotonin | 1983 |
Correlation of changes in alpha 2-adrenoceptor number and locomotor responses to clonidine following clorgyline discontinuation.
Topics: Animals; Clonidine; Clorgyline; Drug Interactions; Male; Motor Activity; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Tritium | 1983 |
Treatment with clorgyline and pargyline differentially decreases clonidine-induced hypotension and bradycardia.
Topics: Animals; Blood Pressure; Clonidine; Clorgyline; Female; Heart Rate; Pargyline; Propylamines; Rats; Rats, Inbred Strains | 1984 |
Self-stimulation responses are altered following long-term but not short-term treatment with clorgyline.
Topics: Animals; Clonidine; Clorgyline; Dose-Response Relationship, Drug; Hypothalamus; Male; Propylamines; Rats; Rats, Inbred Strains; Self Stimulation; Time Factors | 1983 |
Growth hormone response to clonidine unchanged by chronic clorgyline treatment.
Topics: Adult; Clonidine; Clorgyline; Depressive Disorder; Double-Blind Method; Female; Growth Hormone; Humans; Male; Middle Aged; Propylamines | 1982 |
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Affinity Labels; Animals; Benzofurans; Binding, Competitive; Clonidine; Clorgyline; Diazoxide; Dioxanes; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Insulin; Insulinoma; Ligands; Pancreatic Neoplasms; Potassium Channels; Rats; Receptors, Drug; Regression Analysis; Software; Tumor Cells, Cultured | 1994 |
Antidepressant and depressogenic drugs lack consistent effects on hamster circadian rhythms.
Topics: Animals; Antidepressive Agents; Arousal; Circadian Rhythm; Clonidine; Clorgyline; Cricetinae; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Male; Mesocricetus; Motor Activity; Phenelzine; Propranolol | 1994 |
Attenuation of clonidine-induced growth hormone release following chronic glucocorticoid and 5-hydroxytryptamine uptake-inhibiting antidepressant treatments.
Topics: Animals; Antidepressive Agents; Clonidine; Clorgyline; Glucocorticoids; Growth Hormone; Hydrocortisone; Male; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 1994 |
The ambivalent behaviour "stretched approach posture" in the rat as a paradigm to characterize anxiolytic drugs.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Clonidine; Clorgyline; Dose-Response Relationship, Drug; Male; Movement; Posture; Rats; Rats, Wistar | 1995 |
Long-term antidepressant treatment restores clonidine's effect on growth hormone secretion in a genetic animal model of depression.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clonidine; Clorgyline; Depressive Disorder; Desipramine; Female; Fluoxetine; Growth Hormone; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains | 1996 |
Acute and chronic effects of desipramine and clorgyline on alpha(2)-adrenoceptors regulating noradrenergic transmission in the rat brain: a dual-probe microdialysis study.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Brain; Clonidine; Clorgyline; Desipramine; Gyrus Cinguli; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Time Factors | 2001 |
The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain.
Topics: Adrenergic alpha-Agonists; Allyl Compounds; Amine Oxidase (Copper-Containing); Animals; Brain; Cell Membrane; Clonidine; Clorgyline; Drug Combinations; Guanidines; Imidazoline Receptors; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Selegiline | 2003 |