clonidine and chlorthalidone

clonidine has been researched along with chlorthalidone in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	39 (75.00)	18.7374
1990's	5 (9.62)	18.2507
2000's	5 (9.62)	29.6817
2010's	3 (5.77)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Atlas, SA; Laragh, JH; Moon, C; Sealey, JE	1
Hammond, JJ; Kirkendall, WM; Overturf, ML; Thomas, JC; Zama, A	1
Arena, G; Tedesco, V	1
Kissin, E; Rosenthal, T; Stern, N; Teicher, A	1
Davidov, ME; Finnerty, FA; Lee, WR; Mroczek, WJ	1
Antonello, A; Borsatti, A; Campanini, M; Glorioso, S; Todesco, S	1
Gadgil, UG; Noronha, JL; Pinto, IJ; Sunawala, JD	1
Agosta, R; Ambrosioni, E; Magnani, B; Racco, F	1
Rosenman, RH	1
Reisin, E; Weed, SG	1
Liepinia, DJ; Skarda, IJ; Skards, JV; Vitols, AV; Voita, DU	1
Conen, D; Müller, J; Noll, G; Rüttimann, S; Schneider, K	1
Matthews, C; Von Kuhnert, L; Zeller, KR	1
Fagan, TC	1
Farsang, C; Kapocsi, J; Vizi, ES	1
Horning, JR; McNulty, R; Simmons, JL; Williams, L; Zawada, ET	1
Bovenzi, F; Contursi, V; Loiacono, N; Maiorano, G; Petrelli, G; Ricapito, M	1
Bompani, R; Del Vita, M; Scali, G	1
Finnerty, FA; Leibel, BA; Mroczek, WJ	1
Amery, AK; Bossaert, H; Fagard, RH; Verstraete, M	1
Lung-Johansen, P	1
D'Amelio, G; Dalla Volta, S; De Longhi, B; Razzolini, R	1
Perrotta, P	1
Dejaco, RM; Hartl, O	1
Câmpeanu, A; Teodoresco, P	1
Hutchison, JC; Lintgen, AB; Wilkinson, WH	1
Kishimoto, M	1
Davidov, M; Finnerty, FA; Mroczek, WJ	1
Drayer, JI; Hubbell, FA; Rose, DE; Weber, MA	1
Beckenbauer, UE; Planz, G	1
Bibracher, C; Podzich, M	1
Golub, MS; Sambhi, MP; Thananopavarn, C	1
Drayer, JI; Gray, DR; Weber, MA	2
Stonys, DB; Walters, SM	1
Battilana, G; Bellini, G; Carretta, R; Cosenzi, A; Fabris, B; Puppis, E; Rigoni, A; Tonutti, L	1
Grossman, SH; Gunnells, JC	1
Del Guercio, R; Gentile, S	1
Arendt, G; Arndts, D; Doevendans, J; Rippen, G	1
Jain, AK; McMahon, FG; Noveck, RJ; Ryan, JR	1
Cugurra, F	1
Ambrosio, GB; Casiglia, E; Colangeli, G; Di Menza, G; Ginocchio, G; Mazza, A; Onesto, C; Pegoraro, L; Spolaore, P	1
Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT	1
Black, HR; Slim, HB; Thompson, PD	1

Reviews

3 review(s) available for clonidine and chlorthalidone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Side effects of antihypertensive agents]. Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:12 Topics: Antihypertensive Agents; Autonomic Agents; Benzothiadiazines; Benzyl Compounds; Carbamates; Chlorthalidone; Clonidine; Guanethidine; Guanidines; Humans; Hydralazine; Methyldopa; Plants, Medicinal; Plants, Toxic; Rauwolfia; Veratrum	1971
Older blood pressure medications-do they still have a place? The American journal of cardiology, 2011, Jul-15, Volume: 108, Issue:2 Topics: Antihypertensive Agents; Chlorthalidone; Clonidine; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Reserpine; Spironolactone; Vasodilator Agents	2011

Trials

21 trial(s) available for clonidine and chlorthalidone

Article	Year
Prazosin and clonidine for moderately severe hypertension. JAMA, 1978, Dec-01, Volume: 240, Issue:23 Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Polythiazide; Prazosin; Quinazolines	1978
Clonidine and chlorthalidone (combipres) in hypertension. Current therapeutic research, clinical and experimental, 1975, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Combinations; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture	1975
Comparison of the effects of pharmacological therapy and a low-sodium diet on mild hypertension. Clinical science and molecular medicine. Supplement, 1976, Volume: 3 Topics: Adult; Aged; Chlorthalidone; Clonidine; Humans; Hypertension; Middle Aged; Sodium Chloride	1976
The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine. Journal of hypertension, 1992, Volume: 10, Issue:5 Topics: Black People; Blood Pressure; Chlorthalidone; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Middle Aged; Obesity; Prospective Studies	1992
Low-dose clonidine administration in the treatment of mild or moderate essential hypertension: results from a double-blind placebo-controlled study (Clobass). The Clobass Study Group. Journal of hypertension, 1990, Volume: 8, Issue:6 Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Italy; Male; Middle Aged; Multicenter Studies as Topic; Time Factors	1990
Short- and long-term cerebrovascular effects of nitrendipine in hypertensive patients. Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 4 Topics: Adult; Aged; Cerebrovascular Circulation; Chlorthalidone; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Time Factors	1988
Rapid reduction of severe asymptomatic hypertension. A prospective, controlled trial. Archives of internal medicine, 1989, Volume: 149, Issue:10 Topics: Administration, Oral; Chlorthalidone; Clonidine; Drug Administration Schedule; Humans; Hypertension; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence	1989
Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. Chest, 1988, Volume: 93, Issue:5 Topics: Administration, Cutaneous; Chlorthalidone; Clinical Trials as Topic; Clonidine; Dermatitis, Contact; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Time Factors	1988
Comparison of clonidine and methyldopa in hypertensive patients receiving a diuretic. A double-blind crossover study. The American journal of cardiology, 1972, Volume: 29, Issue:5 Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; Chemistry; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Hypertension; Imidazoles; Male; Methyldopa; Middle Aged; Posture; Time Factors	1972
Clonidine versus methyldopa. A double blind cross-over study comparing side effects of clonidine and methyldopa administered together with chlorthalidone at a dosage producing the same blood pressure lowering effect. Acta cardiologica, 1972, Volume: 21, Issue:1 Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Constipation; Depression; Headache; Humans; Hypertension; Hypotension, Orthostatic; Imidazoles; Male; Methyldopa	1972
Haemodynamic changes in long-term therapy of essential hypertension: a comparative study of diuretics, alpha-methyldopa and clonidine. Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1 Topics: Adult; Cardiac Output; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Polythiazide; Vascular Resistance	1973
[Antihypertensive effects of clonidine and of the clonidine-chlorthalidone combination]. Minerva medica, 1974, May-30, Volume: 65, Issue:41 Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Drug Evaluation; Drug Synergism; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged	1974
[Antihypertensive effect of clonidine alone and in combination with chlorthalidone]. La Clinica terapeutica, 1974, Jun-15, Volume: 69, Issue:5 Topics: Adult; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Synergism; Female; Humans; Hypertension; Male; Middle Aged	1974
[Clinical trials with clonidine-chlorthalidone, a combined preparation in the treatment of hypertensive diseases]. Wiener medizinische Wochenschrift (1946), 1973, Feb-17, Volume: 123, Issue:7 Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diabetes Mellitus; Drug Combinations; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Tablets	1973
The use of clonidine hydrochloride in ambulatory hypertensive patients. Angiology, 1971, Volume: 22, Issue:11 Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Placebos; Posture; Time Factors	1971
Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension. Southern medical journal, 1984, Volume: 77, Issue:10 Topics: Adult; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Random Allocation; Renin-Angiotensin System; Time Factors	1984
Effects of low-dose antihypertensive therapy in elderly patients with predominant systolic hypertension. Journal of gerontology, 1983, Volume: 38, Issue:3 Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension; Male; Middle Aged; Posture; Random Allocation	1983
Blood pressure response to a single daily dose of a clonidine-chlorthalidone combination. Journal of clinical pharmacology, 1980, Volume: 20, Issue:4 Topics: Adolescent; Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged	1980
[Nifedipine and essential arterial hypertension refractory to hypotensive therapy: results of a preliminary double-blind study]. La Clinica terapeutica, 1981, Jan-15, Volume: 96, Issue:1 Topics: Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines; Reserpine	1981
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL). Japanese heart journal, 1994, Volume: 35, Issue:5 Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Heart Diseases; Humans; Hypertension; Italy; Male; Nifedipine; Prospective Studies; Survival Analysis	1994
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5 Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People	2007

Other Studies

28 other study(ies) available for clonidine and chlorthalidone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Plasma renin and "prorenin" in essential hypertension during sodium depletion, beta-blockade, and reduced arterial pressure. Lancet (London, England), 1977, Oct-15, Volume: 2, Issue:8042 Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Depression, Chemical; Diet, Sodium-Restricted; Drug Therapy, Combination; Enzyme Precursors; Female; Humans; Hypertension; Male; Middle Aged; Propranolol; Renin; Sodium; Spironolactone	1977
[Effects of high doses of clonidine and chlorthalidone]. La Clinica terapeutica, 1979, Jun-30, Volume: 89, Issue:6 Topics: Chlorthalidone; Clonidine; Drug Synergism; Female; Humans; Hypertension; Hypotension; Middle Aged	1979
[Combined clonidine-chlorthalidone therapy of hypertension]. Harefuah, 1978, Dec-15, Volume: 95, Issue:12 Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension	1978
[Clinical effects of a clonidine-chlorthalidone combination in the treatment of arterial hypertension]. Minerva medica, 1976, Jul-21, Volume: 67, Issue:35 Topics: Adult; Chlorthalidone; Clonidine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Sleep Wake Disorders; Vertigo	1976
Clinical trail with clonidine hydrochloride. The Journal of the Association of Physicians of India, 1976, Volume: 24, Issue:7 Topics: Adult; Aged; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged	1976
Combined clonidine-chlorthalidone therapy in hypertension. Two years' experience in 30 patients. Archives of internal medicine, 1975, Volume: 135, Issue:9 Topics: Adult; Aged; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged	1975
Combipres for hypertension. The Medical letter on drugs and therapeutics, 1975, Sep-12, Volume: 17, Issue:19 Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension	1975
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension. Cor et vasa, 1990, Volume: 32, Issue:1 Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Vascular Resistance	1990
Acute reduction of blood pressure in asymptomatic patients with severe hypertension. An idea whose time has come--and gone. Archives of internal medicine, 1989, Volume: 149, Issue:10 Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Humans; Hypertension; Nifedipine	1989
Prazosin partly blocks clonidine-induced hypotension in patients with essential hypertension. European journal of clinical pharmacology, 1987, Volume: 32, Issue:4 Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Prazosin; Receptors, Adrenergic, alpha	1987
[Clinico-therapeutic evaluation of the hypertensive patient by the isometric exertion test]. Minerva cardioangiologica, 1986, Volume: 34, Issue:3 Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Clonidine; Female; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Muscle Contraction	1986
[Therapy of arterial hypertension with a delayed-action clonidine and chlorthalidone combination]. La Clinica terapeutica, 1985, Apr-30, Volume: 113, Issue:2 Topics: Adult; Aged; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged	1985
[Effects of clonidine treatment in advanced forms of essential arterial hypertension]. Revue roumaine de medecine interne (1964), 1973, Volume: 10, Issue:6 Topics: Aged; Aortic Arch Syndromes; Bradycardia; Cerebral Hemorrhage; Chemical Phenomena; Chemistry; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Furosemide; Hemiplegia; Humans; Hypertension; Ischemia; Kidney Failure, Chronic; Male; Middle Aged; Retinal Hemorrhage	1973
Prolonged treatment with clonidine: comparative antihypertensive effects alone and with a diuretic agent. The American journal of cardiology, 1972, Volume: 30, Issue:5 Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; District of Columbia; Diuretics; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged	1972
[Clonidine-diuretic combination in patients with essential hypertension. Modification of sympathetic activity and blood pressure as well as the reaction following sudden withdrawal]. Fortschritte der Medizin, 1984, Aug-30, Volume: 102, Issue:31-32 Topics: Blood Pressure; Chlorthalidone; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Epinephrine; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Substance Withdrawal Syndrome; Sympathetic Nervous System	1984
[Efficacy of low clonidine doses in galenic sustained-release preparations. Study with Combipresan 75 perlongettes]. MMW, Munchener medizinische Wochenschrift, 1982, May-07, Volume: 124, Issue:18 Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Pulse	1982
Clonidine in the elderly hypertensive. Monotherapy and therapy with a diuretic. Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Time Factors	1983
Combined diuretic and sympatholytic therapy in elderly patients with predominant systolic hypertension. Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension; Kidney; Male; Middle Aged; Potassium; Random Allocation; Renin-Angiotensin System; Time Factors; Uric Acid	1983
Determination of chlorthalidone and clonidine hydrochloride in tablets by HPLC. Journal of chromatographic science, 1983, Volume: 21, Issue:1 Topics: Chlorthalidone; Chromatography, High Pressure Liquid; Clonidine; Tablets	1983
[Comparative evaluation of the extended hypotensive effect of slow-released clonidine administered alone or in association with a diuretic]. La Clinica terapeutica, 1983, May-31, Volume: 105, Issue:4 Topics: Adult; Aged; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged	1983
[Pharmacokinetics of clonidine and chlorthalidone following subacute administration of a fixed combination compared with a sustained release formulation of clonidine alone (author's transl)]. Arzneimittel-Forschung, 1981, Volume: 31, Issue:11 Topics: Adult; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Combinations; Female; Humans; Kinetics; Male	1981
Clonidine-chlorthalidone combination once and twice daily in essential hypertension. Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:5 Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged	1980
[Rubric of good and less good drugs. Clonidine]. Giornale italiano di cardiologia, 1995, Volume: 25, Issue:5 Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension	1995