clonidine and chlordiazepoxide

clonidine has been researched along with chlordiazepoxide in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199015 (45.45)18.7374
1990's5 (15.15)18.2507
2000's10 (30.30)29.6817
2010's3 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Coop, CF; McNaughton, N; Scott, DJ1
Baumgartner, GR; Rowen, RC2
Dunn, AJ; Gorman, AL; Yang, XM1
Freeman, GB; Thurmond, JB2
Baldwin, HA; File, SE1
Baldwin, HA; File, SE; Hitchcott, PK1
Chopin, P; File, SE; Pellow, S2
Sanger, DJ1
Gupta, AK; Jha, BK1
Baumgartner, GR1
Campbell, BC; Reid, JL1
Grilly, DM; Jacoby, D; Johnson, SK; LaRiccia, J; Minardo, R1
Pappas, BA; Walsh, P1
Haertzen, CA; Henningfield, JE; Jasinski, DR; Johnson, RE; Makhzoumi, HM; Miyasato, K1
Squibb, RE; Tilson, HA1
Friedman, LS; Mayo-Smith, MF; Saitz, R1
Redfern, WS; Williams, A1
Goncharenko, NV; Pankrat'ev, DV; Talalaenko, AN1
Gewirtz, JC; Harris, AC1
Abílio, VC; Carvalho, RC; Frussa-Filho, R; Kameda, SR; Niigaki, ST; Silva, RH; Takatsu-Coleman, AL; Tufik, S1
Sharma, V1
Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE1
Ginsburg, BC; Lamb, RJ; Pinkston, JW1

Reviews

1 review(s) available for clonidine and chlordiazepoxide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for clonidine and chlordiazepoxide

ArticleYear
Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial.
    Southern medical journal, 1991, Volume: 84, Issue:3

    Topics: Administration, Cutaneous; Adult; Anxiety; Chlordiazepoxide; Clonidine; Double-Blind Method; Ethanol; Humans; Male; Middle Aged; Psychological Tests; Substance Withdrawal Syndrome

1991
Clonidine in heroin withdrawal syndrome: a controlled study in India.
    British journal of addiction, 1988, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Female; Heroin; Heroin Dependence; Humans; India; Male; Random Allocation; Substance Withdrawal Syndrome

1988
Clonidine versus chlordiazepoxide in acute alcohol withdrawal: a preliminary report.
    Southern medical journal, 1988, Volume: 81, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chlordiazepoxide; Clinical Trials as Topic; Clonidine; Double-Blind Method; Ethanol; Humans; Male; Middle Aged; Random Allocation; Substance Withdrawal Syndrome

1988
Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome.
    Archives of internal medicine, 1987, Volume: 147, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Blood Pressure; Chlordiazepoxide; Clinical Trials as Topic; Clonidine; Ethanol; Heart Rate; Humans; Male; Middle Aged; Random Allocation; Substance Withdrawal Syndrome

1987

Other Studies

28 other study(ies) available for clonidine and chlordiazepoxide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone.
    Neuroscience, 1992, Volume: 46, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amobarbital; Animals; Baclofen; Chlordiazepoxide; Clonidine; Electric Stimulation; Electrodes; Electroencephalography; Flumazenil; Hippocampus; Male; Pindolol; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1992
The involvement of central noradrenergic systems and corticotropin-releasing factor in defensive-withdrawal behavior in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Behavior, Animal; Cerebrospinal Fluid; Chlordiazepoxide; Clonidine; Corticotropin-Releasing Hormone; Humans; Injections, Intraperitoneal; Injections, Intravenous; Male; Neurons; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Recombinant Proteins

1990
Brain amines and effects of chlordiazepoxide on motor activity in response to stress.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:5

    Topics: Animals; Apomorphine; Brain Chemistry; Chlordiazepoxide; Clonidine; Dopamine; Humans; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Norepinephrine; Quipazine; Serotonin; Stress, Psychological

1985
Monoamines and effects of chlordiazepoxide on the corticosterone response to stress.
    Physiology & behavior, 1986, Volume: 37, Issue:6

    Topics: Animals; Apomorphine; Biogenic Amines; Chlordiazepoxide; Clonidine; Corticosterone; Hydroxyindoleacetic Acid; Male; Mice; Quipazine; Stress, Physiological

1986
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil; Motor Activity; Muscle Relaxants, Central; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, GABA-A; Receptors, Purinergic; Social Behavior

1989
Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Anxiety; Chlordiazepoxide; Clonidine; Learning; Male; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1989
The effects of yohimbine on exploratory and locomotor behaviour are attributable to its effects at noradrenaline and not at benzodiazepine receptors.
    Neuropharmacology, 1986, Volume: 25, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepinones; Chlordiazepoxide; Clonidine; Drug Interactions; Exploratory Behavior; Flumazenil; Male; Motor Activity; Rats; Receptors, GABA-A; Yohimbine

1986
Response decrement patterns after neuroleptic and non-neuroleptic drugs.
    Psychopharmacology, 1986, Volume: 89, Issue:1

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Chlordiazepoxide; Clonidine; Clozapine; Conditioning, Operant; Electroshock; Food; Male; Methocarbamol; Morphine; Rats; Rats, Inbred Strains

1986
Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors?
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Benzodiazepinones; Brain; Chlordiazepoxide; Clonidine; Dose-Response Relationship, Drug; Flumazenil; Male; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Social Behavior; Social Environment; Yohimbine

1985
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Normetanephrine; Substance Withdrawal Syndrome; Time Factors; Vanilmandelic Acid

1985
How do tranquilizing agents selectively inhibit conditioned avoidance responding?
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Animals; Avoidance Learning; Chlordiazepoxide; Clonidine; Conditioning, Operant; Diazepam; Male; Morphine; Rats; Rats, Inbred Strains; Reaction Time; Tranquilizing Agents

1984
Behavioral comparison of pentylenetetrazol, clonidine, chlordiazepoxide and diazepam in infant rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:6

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Chlordiazepoxide; Clonidine; Diazepam; Motor Activity; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures

1983
Progress report of the NIDA Addiction Research Center.
    NIDA research monograph, 1982, Volume: 41

    Topics: Analgesics; Buprenorphine; Chlordiazepoxide; Clonidine; Diazepam; Humans; Morphine; National Institutes of Health (U.S.); Substance Withdrawal Syndrome; Substance-Related Disorders; Tobacco Use Disorder; Tolmetin; United States

1982
The effects of acrylamide on the behavioral suppression produced by psychoactive agents.
    Neurotoxicology, 1982, Volume: 3, Issue:1

    Topics: Acrylamides; Animals; Apomorphine; Behavior, Animal; Chlordiazepoxide; Clonidine; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Psychotropic Drugs; Rats; Rats, Inbred F344; Receptors, Dopamine

1982
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
    Journal of general internal medicine, 1995, Volume: 10, Issue:9

    Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine; Data Collection; Diazepam; Drug Administration Schedule; Hypnotics and Sedatives; Inpatients; Lorazepam; Oxazepam; Phenytoin; Substance Withdrawal Syndrome

1995
A re-evaluation of the role of alpha 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat.
    British journal of pharmacology, 1995, Volume: 116, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlordiazepoxide; Clonidine; Dioxanes; Diphenhydramine; Hypnotics and Sedatives; Idazoxan; Imidazoles; Injections, Subcutaneous; Isoquinolines; Male; Maze Learning; Mydriasis; Naphthyridines; Picrotoxin; Rats; Rats, Sprague-Dawley; Yohimbine

1995
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine

2003
Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety.
    Psychopharmacology, 2004, Volume: 171, Issue:2

    Topics: Acoustic Stimulation; Acute Disease; Animals; Chlordiazepoxide; Clonidine; Disease Models, Animal; Injections, Intravenous; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reflex, Startle; Substance Withdrawal Syndrome; Time Factors

2004
Anxiogenic effect of sleep deprivation in the elevated plus-maze test in mice.
    Psychopharmacology, 2004, Volume: 176, Issue:2

    Topics: Animals; Anxiety; Chlordiazepoxide; Clonidine; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Sleep Deprivation

2004
Delirium tremens--a case study.
    The Nursing journal of India, 2003, Volume: 94, Issue:3

    Topics: Adult; Alcohol Withdrawal Delirium; Antihypertensive Agents; Chlordiazepoxide; Clonidine; Humans; Hypertension; Hypnotics and Sedatives; Male; Patient Care Planning

2003
Modelling the anxiety-depression continuum in chicks.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiazepoxide; Clonidine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Interleukin-6; Maprotiline; Social Isolation; Stress, Psychological

2009
Examination of reinforcement magnitude on the pharmacological disruption of fixed-ratio performance.
    Experimental and clinical psychopharmacology, 2009, Volume: 17, Issue:4

    Topics: Animals; Chlordiazepoxide; Clonidine; Cocaine; Columbidae; Conditioning, Operant; Ethanol; Extinction, Psychological; Food Deprivation; Haloperidol; Morphine; Reinforcement Schedule; Reinforcement, Psychology; Time Factors

2009