clonidine has been researched along with cardiovascular agents in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (60.66) | 18.7374 |
| 1990's | 14 (22.95) | 18.2507 |
| 2000's | 7 (11.48) | 29.6817 |
| 2010's | 2 (3.28) | 24.3611 |
| 2020's | 1 (1.64) | 2.80 |
| Authors | Studies |
|---|---|
| Gerber, JG; Nies, AS | 1 |
| Adachi, H; Kodama, K; Ogawa, T; Ohhara, H | 1 |
| Haas, F; Heimisch, W; Mendler, N; Schad, H | 1 |
| Cinquegrana, G; Condorelli, M; Duilio, C; Ferro, G; Spadafora, M; Spinelli, L | 1 |
| Brunner, F; Kukovetz, WR | 1 |
| Caucheteux, D; Gurné, O; Hanet, C; Hue, L; Maldague, P; Pouleur, H; Rousseau, MF | 1 |
| Järvinen, A; Paakkari, I | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Ogiwara, Y | 1 |
| Lang, U; Streller, I; Walland, A | 1 |
| Cohn, JN; Francis, GS | 1 |
| Aknin, P; Auffray, JP; Blin, D; Eon, B; Ouerghemmi, D | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Haniuda, M; Ogiwara, Y | 1 |
| Degoutrie, G; Kaltenbach, M; Landgraf, H; Schräder, R | 1 |
| Snyders, DJ; Van Bogaert, PP | 1 |
| Chiba, S; Furukawa, Y; Ogiwara, Y; Takeda, M | 1 |
| Hashimoto, K; Satoh, H | 1 |
| Krumpl, G; Mayer, N; Raberger, G; Schneider, W | 1 |
| Friedrich, T; Hoffmann, M; Huckauf, H; Kammradt, G; Lichey, J | 1 |
| Krumpl, G; Raberger, G; Schneider, W | 1 |
| Hageman, GR; James, TN; Neely, BH; Urthaler, F | 1 |
| Brezina, M; Harron, DW; Kobinger, W; Lillie, C | 1 |
| Raftery, EB | 1 |
| Kawada, M; Satoh, K; Taira, N | 1 |
| Bokisch, AJ; Walker, RJ | 1 |
| Bouman, LN; Duivenvoorden, JJ; Opthof, T; Treijtel, BW | 1 |
| Hugenholtz, PG; Simoons, ML | 1 |
| Simoons, ML; Tummers, J; van Domburg, R; van Meurs-van Woezik, H | 1 |
| Fitzal, S; Semsroth, M; Zimpfer, M | 1 |
| Harron, DW; Nicholls, DP; Shanks, RG | 1 |
| Kaplan, HR; Smith, RD; Tessman, DK | 1 |
| Khosropour, R; Lackner, F; Zimpfer, M | 1 |
| Fitzal, S; Zimpfer, M | 1 |
| Brutsaert, DL; De Clerck, NM; Sys, SU | 1 |
| Heuberger, S; Tritthart, HA; Windisch, H | 1 |
| Millar, JS; Williams, EM | 1 |
| Arndts, D; Förster, HJ; Leb, G | 1 |
| Balakumaran, K; Simoons, ML | 1 |
| Arndts, D; Justus, H; Rominger, KL; Warnkross, H | 1 |
| Arndts, D; Forster, HJ | 1 |
| Rutteman, AM; Saxena, PR; Schamhardt, HC; van der Hoek, TM; Verdouw, PD | 1 |
| BoSmith, RE; Briggs, I; Heapy, CG | 1 |
| BoSmith, RE; Briggs, I; Sturgess, NC | 1 |
| Boucher, M; Chapuy, E; Chassaing, C | 2 |
| Mutschler, E; Walland, A; Weihs, H | 1 |
| Challinor-Rogers, JL; Hay, TK; McPherson, GA | 1 |
| Brzostek, T; Collen, D; Heidbüchel, H; Janssens, L; Lesaffre, E; Mortelmans, L; Scheys, I; Van de Werf, F; Wackers, FJ; Willems, GM | 1 |
| Lodge, NJ; Smith, MA | 1 |
| Challinor-Rogers, JL; Du, XJ; McPherson, GA; Rosenfeldt, FL | 1 |
| Blue, DR; Dillon, MP; Eglen, RM; Jasper, JR; Lesnick, JD; MacLennan, SJ; Zhu, QM | 1 |
| Castro, JL; Ramirez, A; Ricci, D; Taira, CA | 1 |
| Bretton, C; Clergue, F; Dalle, C; Jirounek, P; Schneider, M | 1 |
| Anderson, JR; Nawarskas, JJ | 1 |
| Cho, S; Hayakawa, Y; Mamoto, T; Mikawa, K; Miyoshi, H; Nishikawa, T; Sumikawa, K | 1 |
| Christensen, LP; Lei, L; Tomanek, RJ; Weiss, RM; Zheng, W; Zhou, R | 1 |
| Baruscotti, M; Bucchi, A; Difrancesco, D | 1 |
| Büter, I; Gams, E; Hohlfeld, T; Schipke, JD; Schmitz-Spanke, S | 1 |
| Beetz, N; Biel, M; Hein, L; Jahns, R; Knaus, A; Lohse, MJ; Zong, X | 1 |
| Hayat, S; Li Kam Wa, ME; Lim, PB; Taraborrelli, P | 1 |
| Bui, AD; Eisenmann, ED; Heikkila, ME; Huntley, MR; Johnson, BL; Rorabaugh, BR; Rose, RM; Seeley, SL; Zoladz, PR | 1 |
| Mar, PL; Raj, SR | 1 |
7 review(s) available for clonidine and cardiovascular agents
| Article | Year |
|---|---|
The autonomic nervous system in congestive heart failure.
Topics: Adrenergic beta-Antagonists; Alprazolam; Animals; Autonomic Nervous System; Benzodiazepines; Blood Vessels; Bromocriptine; Cardiovascular Agents; Catecholamines; Clonidine; Cricetinae; Dogs; Dopamine; Guanabenz; Heart; Heart Failure; Hemodynamics; Humans; Myocardium; Norepinephrine; Physical Exertion; Posture; Prognosis; Receptors, Adrenergic; Reflex; Stress, Physiological; Sympathetic Nervous System | 1986 |
Cardiovascular drug withdrawal syndromes. A potential problem with calcium antagonists?
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Agents; Clonidine; Humans; Substance Withdrawal Syndrome; Sympathetic Nervous System | 1984 |
Cardiovascular drug-drug interactions.
Topics: Absorption; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Biological Availability; Calcium Channel Blockers; Cardiovascular Agents; Clonidine; Cytochrome P-450 Enzyme System; Digoxin; Diuretics; Drug Interactions; Humans; Hypolipidemic Agents; Kidney; Metabolic Clearance Rate; Metabolism; Nitrates; Protein Binding; Ticlopidine; Tissue Distribution | 2001 |
[Alpha2 agonists and their clinical use in anesthesia].
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics; Anesthesia; Blood Circulation; Cardiovascular Agents; Clonidine; Drug Synergism; Drug Therapy, Combination; Humans | 2001 |
Physiology and pharmacology of the cardiac pacemaker ("funny") current.
Topics: Amino Acid Sequence; Animals; Benzazepines; Cardiovascular Agents; Clonidine; Cyclic Nucleotide-Gated Cation Channels; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Nerve Tissue Proteins; Potassium Channels; Pyrimidines; Sinoatrial Node; Structure-Activity Relationship | 2005 |
[Selective I(f) channel inhibition: an alternative for treating coronary artery disease?].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Cardiotonic Agents; Cardiovascular Agents; Clonidine; Coronary Artery Disease; Humans; Isoindoles; Ivabradine; Phthalimides; Practice Guidelines as Topic; Practice Patterns, Physicians' | 2006 |
Postural Orthostatic Tachycardia Syndrome: Mechanisms and New Therapies.
Topics: Adrenergic beta-Antagonists; Cardiovascular Agents; Clonidine; Combined Modality Therapy; Female; Humans; Ivabradine; Male; Methyldopa; Postural Orthostatic Tachycardia Syndrome; Quality of Life; Risk Assessment; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2020 |
6 trial(s) available for clonidine and cardiovascular agents
| Article | Year |
|---|---|
Alinidine in chronic stable angina: the effect on diastolic perfusion time.
Topics: Angina Pectoris; Cardiovascular Agents; Chronic Disease; Clonidine; Diastole; Double-Blind Method; Exercise Test; Humans; Male | 1990 |
[Treatment of hyperkinetic heart syndrome with alinidine and propranolol].
Topics: Adult; Blood Pressure; Cardiovascular Agents; Clonidine; Echocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Neurocirculatory Asthenia; Propranolol | 1987 |
Safety and efficacy of alinidine in symptom-free asthmatics.
Topics: Adult; Asthma; Blood Pressure; Cardiovascular Agents; Clonidine; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Random Allocation; Respiratory Function Tests | 1986 |
Alinidine, a new agent which lowers heart rate in patients with angina pectoris.
Topics: Aged; Angina Pectoris; Blood Pressure; Cardiovascular Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Male; Middle Aged; Physical Exertion | 1982 |
Cardiovascular effects of alinidine and propranolol alone and in combination with hydralazine in normal man.
Topics: Adult; Blood Pressure; Cardiovascular Agents; Clonidine; Heart Rate; Humans; Hydralazine; Male; Posture; Propranolol | 1983 |
Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy.
Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Cardiovascular Agents; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency; Ventricular Function, Left | 1993 |
48 other study(ies) available for clonidine and cardiovascular agents
| Article | Year |
|---|---|
Abrupt withdrawal of cardiovascular drugs.
Topics: Cardiovascular Agents; Clonidine; Hemodynamics; Homeostasis; Humans; Nitroglycerin; Nitroprusside; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Substance Withdrawal Syndrome; Sympathetic Nervous System | 1979 |
Inhibitory effect of a novel antianginal agent, E4080, on ST segment elevation induced by vasopressin in anesthetized guinea pigs.
Topics: Anesthesia; Animals; Benzopyrans; Cardiovascular Agents; Catechols; Clonidine; Coronary Vessels; Cromakalim; Electrocardiography; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isosorbide Dinitrate; Male; Nifedipine; Pyrroles; Vasodilator Agents; Vasopressins | 1992 |
Effect of the 'specific bradycardic agent' alinidine on the function of ischemic myocardium.
Topics: Animals; Anti-Arrhythmia Agents; Cardiovascular Agents; Clonidine; Coronary Circulation; Coronary Disease; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male | 1991 |
Binding of two specific bradycardic agents, alinidine and AQ-A 39, to muscarinic receptors of guinea pig atria and ventricle.
Topics: Animals; Binding, Competitive; Cardiovascular Agents; Clonidine; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Isoindoles; Myocardium; Phthalimides; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic | 1988 |
Effects of alinidine on metabolic response to high-demand myocardial ischemia.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Coronary Disease; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Lactates; Male; Middle Aged; Oxygen Consumption | 1989 |
Continuous monitoring of ventilation in spontaneously breathing anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Cardiovascular Agents; Clonidine; Codeine; Heart Rate; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Respiration; Respiratory Function Tests; Thyrotropin-Releasing Hormone; Tidal Volume | 1989 |
Comparative study of cardiovascular effects of clonidine and alinidine in cross-perfused dog atrial preparations.
Topics: Animals; Cardiovascular Agents; Clonidine; Cross Circulation; Dogs; Heart; Heart Rate; Myocardial Contraction; Parasympatholytics | 1989 |
Alinidine antagonizes the myocardial effects of adenosine.
Topics: Action Potentials; Adenosine; Animals; Atropine; Cardiovascular Agents; Clonidine; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Rats | 1989 |
[Hemodynamic effects of alinidine in the early postoperative phase of cardiac surgery].
Topics: Adult; Aged; Cardiovascular Agents; Clonidine; Female; Heart Diseases; Hemodynamics; Humans; Male; Middle Aged; Postoperative Period; Time Factors | 1988 |
Bradycardic effects of AQ-A 39 (falipamil) in situ and in isolated, blood-perfused dog hearts. Comparison with alinidine and verapamil.
Topics: Animals; Cardiovascular Agents; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart; Heart Atria; Heart Rate; Isoindoles; Myocardial Contraction; Phthalimides; Verapamil | 1988 |
Alinidine modifies the pacemaker current in sheep Purkinje fibers.
Topics: Action Potentials; Animals; Biological Clocks; Cardiovascular Agents; Clonidine; Heart Conduction System; In Vitro Techniques; Iontophoresis; Kinetics; Membrane Potentials; Purkinje Fibers; Sheep | 1987 |
Blocking effects of alinidine on negative chronotropic and inotropic responses to vagal stimulation and injected acetylcholine and carbachol in dogs.
Topics: Acetylcholine; Adenosine; Animals; Atropine; Carbachol; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Heart Rate; Myocardial Contraction; Vagus Nerve | 1987 |
Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells.
Topics: Action Potentials; Animals; Cardiovascular Agents; Clonidine; Depression, Chemical; Diastole; Dose-Response Relationship, Drug; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Rabbits; Sinoatrial Node | 1986 |
Effects of alinidine on exercise-induced regional contractile dysfunction in dogs.
Topics: Animals; Cardiovascular Agents; Clonidine; Dogs; Female; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Physical Exertion; Time Factors | 1986 |
Can exercise-induced regional contractile dysfunction be prevented by selective bradycardic agents?
Topics: Animals; Arrhythmias, Cardiac; Benzazepines; Cardiovascular Agents; Clonidine; Dogs; Hemodynamics; Male; Myocardial Contraction; Physical Exertion; Propranolol | 1986 |
Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction.
Topics: Acetylcholine; Animals; Atrioventricular Node; Atropine; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; Male; Norepinephrine; Parasympathetic Nervous System; Parasympatholytics; Premedication; Propranolol; Sinoatrial Node; Stellate Ganglion; Time Factors; Vagus Nerve | 1985 |
Antifibrillatory properties of alinidine after coronary artery occlusion in rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Clonidine; Coronary Disease; Electrocardiography; Heart Rate; Hemodynamics; Male; Mexiletine; Rats; Rats, Inbred Strains; Risk; Ventricular Fibrillation | 1985 |
Selectivity of alinidine, a bradycardic agent, for SA nodal automaticity versus other cardiac activities in isolated, blood-perfused dog-heart preparations.
Topics: Animals; Atrioventricular Node; Cardiovascular Agents; Clonidine; Coronary Circulation; Dogs; Female; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Sinoatrial Node | 1984 |
Interactions between alinidine and responses to acetylcholine, dopamine and 5-hydroxytryptamine of specific Helix central neurones.
Topics: Acetylcholine; Action Potentials; Animals; Brain; Cardiovascular Agents; Clonidine; Dopamine; Helix, Snails; Neurons; Serotonin; Sodium | 1983 |
Electrophysiological effects of alinidine on nodal and atrial fibers in the guinea-pig heart.
Topics: Action Potentials; Animals; Cardiovascular Agents; Clonidine; Diastole; Female; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Sinoatrial Node | 1984 |
Haemodynamic effects of alinidine, a specific sinus node inhibition, in patients with unstable angina or myocardial infarction.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Cardiac Output; Cardiovascular Agents; Clonidine; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction | 1984 |
Relative roles of heart rate and ventricular stroke volume for the regulation of cardiac output during controlled hypotension with sodium nitroprusside in man.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiovascular Agents; Clonidine; Ferricyanides; Heart Rate; Humans; Hypotension, Controlled; Middle Aged; Nitroprusside; Stroke Volume | 1982 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
Effect of dobutamine on cardiac function in man: reciprocal roles of heart rate and ventricular stroke volume.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiovascular Agents; Catecholamines; Clonidine; Dobutamine; Drug Interactions; Heart Rate; Humans; Middle Aged; Stroke Volume; Surgical Procedures, Operative | 1982 |
Cardiovascular effects of N-allyl clonidine (ST 567, alinidine): a substance with specific bradycardiac action during neuroleptanesthesia in humans.
Topics: Adult; Aged; Blood Pressure; Cardiovascular Agents; Clonidine; Heart Rate; Hemodynamics; Humans; Middle Aged; Neuroleptanalgesia; Nitroprusside | 1982 |
Effects of alinidine on myocardial contraction and relaxation.
Topics: Animals; Cardiovascular Agents; Cats; Clonidine; In Vitro Techniques; Muscle Relaxation; Myocardial Contraction; Papillary Muscles; Sarcoplasmic Reticulum | 1982 |
The effects of the bradycardia-producing compound alinidine on action potentials and tension development in cardiac fibres.
Topics: Action Potentials; Animals; Barium; Bradycardia; Calcium; Cardiovascular Agents; Chick Embryo; Clonidine; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Muscle Tonus; Papillary Muscles | 1981 |
Pacemaker selectivity: influence on rabbit atria of ionic environment and of alinidine, a possible anion antagonist.
Topics: Animals; Atrial Function; Atropine; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Female; Heart Atria; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Rabbits; Sinoatrial Node | 1981 |
Pharmacokinetics and metabolism of 14C-labelled alinidine in man and dogs.
Topics: Administration, Oral; Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Cardiovascular Agents; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Clonidine; Dogs; Female; Humans; Injections, Intravenous; Kinetics; Male; Mass Spectrometry | 1981 |
The effects of drugs on the exercise electrocardiogram.
Topics: Cardiovascular Agents; Clonidine; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Propranolol; Vasodilator Agents; Verapamil | 1981 |
Proof of the linearity of the pharmacokinetics of alinidine in man.
Topics: Administration, Oral; Adult; Cardiovascular Agents; Clonidine; Humans; Kinetics; Male; Models, Biological; Radioimmunoassay | 1981 |
New aspects in the metabolism of alinidine in man.
Topics: Cardiovascular Agents; Clonidine; Humans | 1981 |
The effects of alinidine, an N-allyl derivative of clonidine, on regional myocardial perfusion and performance in the pig with or without atrial pacing.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular Agents; Cerebrovascular Circulation; Clonidine; Coronary Circulation; Electrocardiography; Heart; Heart Rate; Hemodynamics; Kidney; Myocardial Contraction; Oxygen Consumption; Pacemaker, Artificial; Perfusion; Stroke Volume; Swine; Vascular Resistance | 1980 |
Effects of Zeneca ZD7288 in comparison with alinidine and UL-FS 49 on guinea pig sinoatrial node and ventricular action potentials.
Topics: Action Potentials; Animals; Benzazepines; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Papillary Muscles; Pyrimidines; Sinoatrial Node | 1994 |
Inhibitory actions of ZENECA ZD7288 on whole-cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzazepines; Cardiovascular Agents; Clonidine; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Pyrimidines; Sinoatrial Node | 1993 |
Cardiac electrophysiologic effects of alinidine, a specific bradycardic agent, in the conscious dog: plasma concentration-response relations.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Blood Pressure; Bundle of His; Cardiovascular Agents; Clonidine; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Heart Rate; Injections, Intravenous; Male; Sinoatrial Node | 1995 |
Alinidine prevents hypoperfusion-induced transmural flow redistribution in isolated paced rat hearts.
Topics: Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Coronary Circulation; Heart; In Vitro Techniques; Male; Microspheres; Myocardial Contraction; Rats; Rats, Inbred Strains; Ventricular Pressure | 1994 |
Comparison of the cromakalim antagonism and bradycardic actions of a series of novel alinidine analogues in the rat.
Topics: Animals; Benzopyrans; Cardiovascular Agents; Clonidine; Cromakalim; Heart Rate; In Vitro Techniques; Male; Potassium Channels; Pyrroles; Rats; Structure-Activity Relationship | 1994 |
Cardiac electrophysiological effects of falipamil in the conscious dog: comparison with alinidine.
Topics: Animals; Atrioventricular Node; Blood Pressure; Bundle of His; Cardiovascular Agents; Clonidine; Dogs; Electroencephalography; Electrophysiology; Female; Heart; Heart Rate; Isoindoles; Male; Phthalimides; Sinoatrial Node | 1996 |
The novel cardioprotective agent BMS-180448 activates a potassium conductance in cardiac and vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cardiotonic Agents; Cardiovascular Agents; Cells, Cultured; Clonidine; Glyburide; Guanidines; Guinea Pigs; Heart Ventricles; Male; Muscle, Smooth, Vascular; Myocardium; Patch-Clamp Techniques; Potassium Channels; Rabbits; Rubidium Radioisotopes | 1996 |
Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Heart; Male; Potassium Channel Blockers; Rats; Rats, Inbred WKY; Reperfusion Injury; Structure-Activity Relationship | 1997 |
Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild-type and D79N alpha2A-adrenoceptor transgenic mice.
Topics: Adrenergic alpha-Antagonists; Amino Acid Substitution; Animals; Binding, Competitive; Blood Pressure; Cardiovascular Agents; Cell Line; Clonidine; Consciousness; Dogs; Heart Rate; Humans; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Mutation; Naphthyridines; Oxazoles; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Rilmenidine; Saphenous Vein; Tritium | 1999 |
Central benzodiazepine involvement in clonidine cardiovascular actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Carbolines; Cardiovascular Agents; Clonidine; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Heart Rate; Infusions, Intravenous; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Stereotaxic Techniques; Time Factors; Yohimbine | 1999 |
Inhibition of the I(h) current in isolated peripheral nerve: a novel mode of peripheral antinociception?
Topics: Action Potentials; Adrenergic alpha-Agonists; Analgesics; Animals; Barium; Cardiovascular Agents; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Nerve Fibers; Nerve Fibers, Myelinated; Peripheral Nerves; Pyrimidines; Rabbits; Sucrose; Vagus Nerve | 2001 |
Bradycardia induces angiogenesis, increases coronary reserve, and preserves function of the postinfarcted heart.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Bradycardia; Cardiovascular Agents; Clonidine; Coronary Vessels; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Heart Ventricles; Hypertrophy, Left Ventricular; Ligation; Male; Models, Animal; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Stroke Volume; Ultrasonography; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine.
Topics: Animals; Bradycardia; Cardiovascular Agents; Cell Line; Clonidine; Cyclic Nucleotide-Gated Cation Channels; Female; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Male; Mice; Mice, Inbred Strains; Muscle Proteins; Potassium Channels; Sympathetic Nervous System | 2007 |
Respiration driven excessive sinus tachycardia treated with clonidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Benzazepines; Cardiovascular Agents; Clonidine; Cough; Drug Therapy, Combination; Dyspnea; Echocardiography; Electrocardiography; Humans; Inhalation; Ivabradine; Male; Syncope; Tachycardia; Tachycardia, Sinus; Treatment Outcome | 2017 |
Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder.
Topics: Adrenergic Agents; Animals; Anxiety; Cardiovascular Agents; Clonidine; Disease Models, Animal; Disease Susceptibility; Heart; Male; Myocardial Ischemia; Myocardium; Propranolol; Random Allocation; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Sympathetic Nervous System; Treatment Failure | 2019 |