clonidine has been researched along with baclofen in 141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (23.40) | 18.7374 |
| 1990's | 33 (23.40) | 18.2507 |
| 2000's | 36 (25.53) | 29.6817 |
| 2010's | 34 (24.11) | 24.3611 |
| 2020's | 5 (3.55) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Smith, DF; Vestergaard, P | 1 |
| Evans, RH; Long, SK; Siarey, RJ | 1 |
| Holdcroft, A; Nicol, ME | 1 |
| Coop, CF; McNaughton, N; Scott, DJ | 1 |
| Sandford, PR; Sawasky, KB; Spengler, SE | 1 |
| Milanov, IG | 1 |
| Chokroverty, S; Hening, WA; Walters, AS | 1 |
| Dietz, V | 1 |
| Cerný, R; Jerábek, J; Krejcová, H; Vyskocilová, M | 1 |
| Sawynok, J; Steardo, L | 1 |
| Ballejo, G; Calixto, JB; Strobel, GH | 1 |
| Aley, KO; Kulkarni, SK | 1 |
| Gurchin, FA; Kirsanova, GV; Naryshkin, AG; Samoĭlov, KA; Shvets, IaM; Vasilevskaia, LS | 1 |
| Paulig, M; Pellkofer, M | 1 |
| Ciblis, D; Medici, M; Pebet, M | 1 |
| Rice, GP | 2 |
| Andreev, BV; Ignatov, IuD | 1 |
| Reid, A; Sawynok, J | 2 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Wüllner, U | 1 |
| Bloomfield, MR; Fillenz, M | 1 |
| Kharin, NA; Komissarov, IV; Serdiuk, SE | 1 |
| Boisson, D; Eyssette, M; Rohmer, F; Serratrice, G; Warter, JM | 1 |
| Bass, B; Bouchard, S; Cameron, MG; Ebers, GC; Hader, W; Noseworthy, JH; Rice, GP; Weinshenker, B | 1 |
| Hoogstraten, MC; Minderhoud, JM; van der Ploeg, RJ; van Marle, S; vd Burg, W; Vreeling, A | 1 |
| Nordal, HJ; Oftedal, SI; Slettebø, M; Stien, R | 1 |
| Enna, SJ; Zorn, SH | 1 |
| Delwaide, PJ | 1 |
| Reddy, SV; Yaksh, TL | 1 |
| Davies, J | 1 |
| Dackis, CA; Gold, MS; Washton, AM | 1 |
| Auer, LM; Johansson, BB | 1 |
| McLellan, DL | 1 |
| Davies, J; Johnston, SE | 1 |
| Hudgson, P; Newman, PK; Newman, PM; Nogues, M; Weightman, D | 1 |
| Muff, S; Smolenski, C; Smolenski-Kautz, S | 1 |
| Corston, RN; Godwin-Austen, RB; Johnson, F | 1 |
| Fenton, HM; Liebman, JM | 1 |
| Hassan, N; McLellan, DL | 1 |
| Baeyens, JM; Ocaña, M | 1 |
| Evans, RH; Long, SK; Siarey, RJ; Tulp, MT | 1 |
| Nance, PW | 1 |
| Davis, C; Emre, M; Groves, L; Lataste, X | 1 |
| Bédard, PJ; Gomez-Mancilla, B | 1 |
| Birch, PJ; Elliott, PJ; Harrison, SM; Smith, GD; Wiseman, J | 1 |
| Ault, B; Hildebrand, LM | 1 |
| Middleton, JW; Molloy, AR; Rutkowski, SB; Siddall, PJ; Walker, S | 1 |
| Feldman, JL; Johnson, SM; Smith, JC | 1 |
| Skoog, B | 1 |
| Chieng, B; Christie, MD | 1 |
| Malinovsky, JM; Pinaud, M | 1 |
| Matsumoto, K; Nguyen, TT; Watanabe, H | 1 |
| Birder, LA; de Groat, WC | 1 |
| Czuczwar, SJ; Dzieciuch, JA; Kleinrok, Z; Przesmycki, K | 2 |
| Barbeau, H; Norman, KE; Pépin, A | 1 |
| Brenner, R; Hyman, N; Knobler, R; O'Brien, M; Stephan, T | 1 |
| Groves, L; Novack, GD; Shah, J; Shellenberger, MK | 1 |
| Amabeoku, GJ | 1 |
| Harmon, RL; Stolp-Smith, KA | 1 |
| Hao, JX; Wiesenfeld-Hallin, Z; Xu, IS; Xu, XJ | 1 |
| Bocchi, C; Delsignore, R; Fontanesi, B; Gerra, G; Rustichelli, P; Timpano, M; Zaimovic, A; Zambelli, U | 1 |
| Goodkin, DE; Kita, M | 1 |
| Adone, R; Pagliacci, C; Taricco, M; Telaro, E | 1 |
| Bartolini, A; Bellucci, C; Dei, S; Galeotti, N; Ghelardini, C; Gualtieri, F; Manetti, D; Romanelli, MN; Scapecchi, S; Teodori, E | 1 |
| Müller, EE; Rigamonti, AE | 1 |
| Ahmadi-Abhari, SA; Akhondzadeh, S; Assadi, SM; Farzanehgan, ZM; Kashani, AR; Shabestari, OL | 1 |
| Noth, J | 1 |
| Ahmadi-Abhari, SA; Akhondzadeh, S; Assadi, SM; Farzanehgan, ZM; Kamlipour, A; Shabestari, OL | 1 |
| Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ | 1 |
| Elovic, E | 1 |
| Autti-Rämö, I | 1 |
| Schapiro, RT | 1 |
| Rösche, J | 1 |
| Anderson, PM; Lloyd, AC; Rushton, DN | 1 |
| Alva, H; Blednov, YA; Harris, RA; Stoffel, M | 1 |
| Al-Shahrani, AM | 1 |
| Freitag, FG | 1 |
| Ben Smaïl, D; Bussel, B; Chartier-Kastler, E; Denys, P; Even-Schneider, A; Rémy-Néris, O | 1 |
| McCleane, G | 1 |
| Favre, J; Galarza, M; Janszen, M; Taha, A; Taha, J | 1 |
| Alvarez, JC; Chartier-Kastler, E; De Mazancourt, P; Denys, P | 1 |
| Yelnik, AP | 1 |
| Das, SK; Guha, G; Misra, AK; Ray, BK | 1 |
| Alzheimer, C; Kovalev, G; Schibaev, N; Vorobyov, V | 1 |
| Patel, DR; Soyode, O | 1 |
| Adone, R; Pagliacci, MC; Taricco, M; Telaro, E | 1 |
| He, L; Wu, B; Zhou, M | 1 |
| Haase, M; Habersang, R; Lubsch, L; Luedtke, S | 1 |
| Jacobs, BW; Saulino, M | 1 |
| Ben-Smail, D; Bussel, B; Chartier-Kastler, E; Denys, P; Remy-Neris, O; Ruffion, A; Schneider, AE | 1 |
| Taira, T | 1 |
| Awan, S; Dai, AI; Wasay, M | 1 |
| Bensmail, D; Chaleat-Valayer, E; Decq, P; Dehail, P; Dumarcet, N; Marque, P; Parratte, B; Pellas, F; Quentin, V; Rousseaux, M; Simon, O; Trocello, JM; Uzzan, M; Yelnik, AP | 1 |
| Chiravuri, S; Couch, JP; Liu, H; Ruan, X; Wang, F | 1 |
| Lind, G; Linderoth, B; Meyerson, BA; Schechtmann, G; Winter, J | 1 |
| Benecke, R; Patejdl, R | 1 |
| Deer, T; Rauck, RL; Wallace, MS | 1 |
| Kuks, JB; Lapeyre, E; Meijler, WJ | 1 |
| Simon, O; Yelnik, AP | 1 |
| Delgado, MR; Tilton, A; Vargus-Adams, J | 1 |
| Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhou, M | 1 |
| Kaptsov, V; Kovalev, G; Schibaev, N; Sengpiel, F; Vorobyov, V | 1 |
| Chen, CL; Chung, CY; Wong, AM | 1 |
| Hanafusa, N; Kawasaki, H; Okamoto, K; Takatori, S | 1 |
| Heinzlef, O; Monteil-Roch, I | 1 |
| Gillard, P; Graham, GD; Halpern, R; Varon, SF; Zorowitz, RD | 1 |
| Chu, VW; Hornby, TG; Schmit, BD | 1 |
| Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M | 1 |
| Allen, NM; King, MD; Lin, JP; Lynch, T | 1 |
| Lipták, J | 1 |
| Asensio-Samper, JM; De Andres, J; Fabregat-Cid, G | 1 |
| Aksoy, SN; Dai, AI; Demiryürek, AT | 1 |
| Banov, D; Bassani, AS | 1 |
| Álvarez-Ossorio, L; Haupts, M; Jonas, A; Vila, C; Witte, K | 1 |
| Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
| Kouzouna, A; Lindsay, C; Pandyan, AD; Simcox, C | 1 |
| Achey, R; Bethoux, F; Dai, L; Jones, J; Lang, M; Lee, BS; Lobel, DA; Machado, AG; Nagel, SJ | 1 |
| Fu, X; Li, J; Li, M; Ma, Q; Wang, C; Wang, Y; Wu, H; Yang, W | 1 |
| Donato, AA; Hao, D; Olugbodi, A; Udechukwu, N | 1 |
| Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R | 1 |
| Brock, C; Hultin, L; Lindström, E; Lykkesfeldt, J; Nissen, TD | 1 |
| Abouihia, A; Calabrese, A; Cloud, G; Creamer, M; Francisco, GE; Kossmehl, P; Saltuari, L; Ward, AB; Wissel, J; Yochelson, M; Zampolini, M | 1 |
| Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M | 1 |
| Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E | 1 |
| Aletraris, L; Paino, M; Roman, PM | 1 |
| Centonze, D; Comi, G; Leocani, L; Otero-Romero, S; Solari, A | 1 |
| Jones, É; Vlachou, S | 1 |
| Bohn, E; Falck-Ytter, Y; Fehlings, D; Goren, K; Switzer, L | 1 |
| Acton, EK; Bilker, WB; Brensinger, CM; Dawwas, GK; Hennessy, S; Leonard, CE; Li, L; Miano, TA; Neuman, M; Nguyen, TPP; Soprano, SE; Wang, L; Woody, G; Yu, E | 1 |
40 review(s) available for clonidine and baclofen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Review and videotape recognition of idiopathic restless legs syndrome.
Topics: Anti-Anxiety Agents; Arousal; Baclofen; Benzodiazepines; Bromocriptine; Carbamazepine; Clonidine; Humans; Levodopa; Narcotics; Restless Legs Syndrome; Sleep Stages; Videotape Recording | 1991 |
[Spasticity: therapy of increased reflexes or movement disorder?].
Topics: Baclofen; Clonidine; Combined Modality Therapy; Dantrolene; Diazepam; Glycine; Humans; Locomotion; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Muscles; Phenothiazines; Reflex, Abnormal | 1990 |
Pharmacotherapy of spasticity: some theoretical and practical considerations.
Topics: Baclofen; Benzodiazepines; Clonidine; Dantrolene; Humans; Muscle Spasticity; Parasympatholytics | 1987 |
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.
Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1984 |
Comparative profile of tizanidine in the management of spasticity.
Topics: Activities of Daily Living; Baclofen; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus | 1994 |
[Neurotoxicity of intrathecally administrated agents].
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Baclofen; Calcitonin; Clonidine; Humans; Meninges; Midazolam; Nerve Fibers; Somatostatin; Spinal Cord | 1996 |
An approach to switching patients from baclofen to tizanidine.
Topics: Baclofen; Clinical Competence; Clonidine; Humans; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Spinal Cord Diseases; Spinal Cord Injuries | 1998 |
Drugs used to treat spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Drug Administration Schedule; Humans; Muscle Relaxants, Central; Muscle Spasticity | 2000 |
Pharmacological interventions for spasticity following spinal cord injury.
Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Parasympatholytics; Spasm; Spinal Cord Injuries | 2000 |
Principles of pharmaceutical management of spastic hypertonia.
Topics: Anti-Dyskinesia Agents; Baclofen; Benzodiazepines; Botulinum Toxins; Brain Injuries; Clonidine; Dantrolene; GABA Agonists; Humans; Motor Neuron Disease; Muscle Spasticity; Spinal Cord Injuries | 2001 |
[Treatment of spasticity].
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Clonidine; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Quality of Life | 1999 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia | 2001 |
Anti-spasticity medications.
Topics: Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Parasympatholytics | 2003 |
Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role?
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; GABA Agonists; Humans; Migraine Disorders; Muscle Relaxants, Central; Neuromuscular Agents; Tension-Type Headache | 2003 |
[Intrathecal therapy for bladder hyperreflexia].
Topics: Adrenergic alpha-Agonists; Baclofen; Clonidine; Female; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Sexual Dysfunction, Physiological; Spinal Cord Injuries; Urinary Bladder, Neurogenic | 2003 |
Pharmacological management of neuropathic pain.
Topics: Analgesics, Opioid; Anesthetics, Local; Anticonvulsants; Antidepressive Agents, Tricyclic; Baclofen; Capsaicin; Clonidine; Complementary Therapies; Humans; Nervous System; Pain; Selective Serotonin Reuptake Inhibitors | 2003 |
[Pharmacology and upper limb poststroke spasticity: a review. International Society of Prosthetics and Orthotics].
Topics: Arm; Baclofen; Botulinum Toxins, Type A; Clonidine; Combined Modality Therapy; Dantrolene; Ergonomics; Ethanol; Humans; Injections, Intramuscular; Injections, Spinal; Muscle Denervation; Muscle Spasticity; Neuromuscular Agents; Neuromuscular Blockade; Phenol; Physical Therapy Modalities; Stroke | 2004 |
Pharmacologic interventions for reducing spasticity in cerebral palsy.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Clonidine; Dantrolene; Diazepam; Ethanol; Humans; Infant; Injections, Intramuscular; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Phenol; Time Factors | 2005 |
Pharmacological interventions for spasticity following spinal cord injury: results of a Cochrane systematic review.
Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Spasticity; Randomized Controlled Trials as Topic; Spinal Cord Injuries | 2006 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2006 |
The pharmacological management of spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Spasticity | 2006 |
[Chronic intrathecal drug administration for the control of intractable pain].
Topics: Amines; Analgesics, Opioid; Anesthetics, Local; Baclofen; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Morphine; Neoplasms; Neuralgia; omega-Conotoxins; Pain, Intractable | 2008 |
[New therapies for spastic movement disorders].
Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Injections, Intramuscular; Injections, Spinal; Movement Disorders; Muscle Relaxants, Central; Muscle Spasticity; Parasympatholytics; Physical Therapy Modalities; Tolperisone | 2009 |
Ziconotide combination intrathecal therapy: rationale and evidence.
Topics: Analgesics; Baclofen; Clonidine; Drug Therapy, Combination; Humans; Injections, Spinal; Morphine; omega-Conotoxins; Pain; Treatment Outcome | 2010 |
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome | 2010 |
Managing spasticity with drugs.
Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Clonidine; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents | 2010 |
Pharmacologic treatment of spasticity in children.
Topics: Age Factors; Baclofen; Botulinum Toxins; Child; Clonidine; Dantrolene; Diazepam; Humans; Injections, Spinal; Muscle Spasticity; Neuromuscular Agents | 2010 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2011 |
Pharmacotherapy of spasticity in children with cerebral palsy.
Topics: Baclofen; Benzodiazepines; Cerebral Palsy; Child; Clonidine; Dantrolene; Humans; Muscle Spasticity; Neuromuscular Blocking Agents | 2011 |
[Pharmacological treatment of spasticity in multiple sclerosis].
Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin | 2012 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2013 |
Status dystonicus: a practice guide.
Topics: Adolescent; Baclofen; Child; Child, Preschool; Chloral Hydrate; Clonidine; Combined Modality Therapy; Conscious Sedation; Critical Pathways; Deep Brain Stimulation; Diagnosis, Differential; Dystonic Disorders; Emergencies; Humans; Infant; Injections, Spinal; Intensive Care Units, Pediatric; Intubation, Gastrointestinal; Pallidotomy; Risk Factors; Thalamus | 2014 |
Intrathecal delivery of analgesics.
Topics: Analgesics, Opioid; Baclofen; Bupivacaine; Catheters, Indwelling; Chronic Pain; Clonidine; Drug Delivery Systems; Humans; Inflammation; Infusion Pumps, Implantable; Injections, Spinal; Neoplasms; omega-Conotoxins; Psychiatric Status Rating Scales; Spine | 2014 |
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol | 2016 |
Pharmacological interventions other than botulinum toxin for spasticity after stroke.
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Randomized Controlled Trials as Topic; Stroke; Tolperisone | 2016 |
A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis.
Topics: Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Transcutaneous Electric Nerve Stimulation | 2018 |
Pharmacological therapies for management of opium withdrawal.
Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol | 2018 |
A Critical Review of the Role of the Cannabinoid Compounds Δ
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Baclofen; Cannabidiol; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Approval; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Multiple Sclerosis; Spinal Cord; Treatment Outcome; United States; United States Food and Drug Administration | 2020 |
Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta-analysis.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Clonidine; Deep Brain Stimulation; Dystonia; Humans; Injections, Spinal; Levodopa; Neurosurgical Procedures; Trihexyphenidyl | 2021 |
21 trial(s) available for clonidine and baclofen
| Article | Year |
|---|---|
[Comparative double-blind study of the effectiveness and tolerance of baclofen, tetrazepam and tizanidine in spastic movement disorders of the lower extremities].
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Random Allocation | 1989 |
A double-blind, long-term study of tizanidine ('Sirdalud') in spasticity due to cerebrovascular lesions.
Topics: Adult; Aged; Baclofen; Cerebrovascular Disorders; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity | 1989 |
Multi-centre, double-blind trial of a novel antispastic agent, tizanidine, in spasticity associated with multiple sclerosis.
Topics: Adult; Aged; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity | 1988 |
Tizanidine versus baclofen in the treatment of spasticity in patients with multiple sclerosis.
Topics: Adult; Aged; Baclofen; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity | 1988 |
The treatment of spasticity in multiple sclerosis: a double-blind clinical trial of a new anti-spastic drug tizanidine compared with baclofen.
Topics: Adult; Aged; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity | 1987 |
Tizanidine in the treatment of spasticity.
Topics: Adult; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Spasticity; Time Factors | 1982 |
A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.
Topics: Adult; Aged; Baclofen; Chronic Disease; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity | 1981 |
The assessment of drug treatment of spastic gait.
Topics: Aged; Baclofen; Clinical Trials as Topic; Clonidine; Female; Gait; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity | 1981 |
A comparison of clonidine, cyproheptadine and baclofen in spastic spinal cord injured patients.
Topics: Baclofen; Clonidine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Administration Schedule; H-Reflex; Humans; Muscle Spasticity; Muscle Tonus; Muscle, Skeletal; Neural Inhibition; Neurologic Examination; Range of Motion, Articular; Spinal Cord Injuries; Vibration | 1994 |
Effects of drugs on walking after spinal cord injury.
Topics: Adrenergic alpha-Agonists; Adult; Baclofen; Clonidine; Cyproheptadine; Electromyography; Exercise Test; GABA Agonists; Humans; Serotonin Antagonists; Spinal Cord Injuries; Walking | 1998 |
A controlled pharmacokinetic evaluation of tizanidine and baclofen at steady state.
Topics: Adrenergic alpha-Agonists; Adult; Area Under Curve; Baclofen; Biotransformation; Clonidine; Drug Interactions; Half-Life; Humans; Male; Muscle Relaxants, Central | 1999 |
Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; GABA Agents; Heroin Dependence; Humans; Inactivation, Metabolic; Ketoprofen; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxazepam; Patient Compliance; Substance Withdrawal Syndrome; Treatment Outcome | 2000 |
Double-blind randomized controlled trial of baclofen vs. clonidine in the treatment of opiates withdrawal.
Topics: Adult; Baclofen; Clonidine; Double-Blind Method; Humans; Male; Middle Aged; Narcotics; Substance Withdrawal Syndrome | 2000 |
Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial.
Topics: Adult; Analgesics; Baclofen; Clonidine; Double-Blind Method; Humans; Male; Muscle Relaxants, Central; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2001 |
Cost-effectiveness comparison of tizanidine and baclofen in the management of spasticity.
Topics: Baclofen; Clonidine; Cost-Benefit Analysis; Humans; Muscle Relaxants, Central; Muscle Spasticity; United Kingdom | 2002 |
Botulinum toxin type A with oral baclofen versus oral tizanidine: a nonrandomized pilot comparison in patients with cerebral palsy and spastic equinus foot deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Chi-Square Distribution; Child; Child, Preschool; Clonidine; Drug Therapy, Combination; Equinus Deformity; Female; Humans; Male; Muscle Relaxants, Central; Neuromuscular Agents; Pilot Projects; Treatment Outcome | 2008 |
Intrathecal clonidine and baclofen enhance the pain-relieving effect of spinal cord stimulation: a comparative placebo-controlled, randomized trial.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electric Stimulation Therapy; Female; GABA Agonists; Humans; Injections, Spinal; Male; Middle Aged; Peripheral Nervous System Diseases; Placebos; Up-Regulation | 2010 |
Effect of antispastic drugs on motor reflexes and voluntary muscle contraction in incomplete spinal cord injury.
Topics: Adult; Baclofen; Clonidine; Cross-Over Studies; Double-Blind Method; Electromyography; Humans; Isometric Contraction; Lower Extremity; Male; Middle Aged; Muscle Relaxants, Central; Muscle Strength; Pilot Projects; Reflex, Stretch; Spinal Cord Injuries; Torque | 2014 |
Influence of Previous Failed Antispasticity Therapy on the Efficacy and Tolerability of THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity.
Topics: Adult; Baclofen; Cannabidiol; Clonidine; Dronabinol; Drug Combinations; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Parasympatholytics; Plant Extracts | 2016 |
Effect of Intrathecal Baclofen on Pain and Quality of Life in Poststroke Spasticity.
Topics: Administration, Oral; Aged; Baclofen; Benzodiazepines; Clonidine; Dantrolene; Female; Humans; Infusions, Spinal; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Pain; Pain Measurement; Patient Satisfaction; Physical Therapy Modalities; Quality of Life; Severity of Illness Index; Stroke; Stroke Rehabilitation; Treatment Outcome | 2018 |
A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain.
Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Baclofen; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Low Back Pain; Male; Muscle Relaxants, Central; Oxazolidinones; Treatment Outcome | 2019 |
80 other study(ies) available for clonidine and baclofen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
The role of monoamines for the central effects of Baclofen on behavior of rats.
Topics: Anesthesia; Animals; Ataxia; Baclofen; Catecholamines; Clonidine; Dopamine; Injections, Intraventricular; Male; Motor Activity; Norepinephrine; Rats | 1979 |
The effect of centrally acting myorelaxants on NMDA receptor-mediated synaptic transmission in the immature rat spinal cord in vitro.
Topics: Animals; Baclofen; Clonidine; Diazepam; In Vitro Techniques; Muscle Relaxants, Central; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Tetrodotoxin | 1992 |
Density of intrathecal agents.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Baclofen; Body Temperature; Cerebrospinal Fluid; Clonidine; Droperidol; Humans; Methadone; Midazolam; Naloxone; Specific Gravity; Temperature | 1992 |
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amobarbital; Animals; Baclofen; Chlordiazepoxide; Clonidine; Electric Stimulation; Electrodes; Electroencephalography; Flumazenil; Hippocampus; Male; Pindolol; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1992 |
Clonidine in the treatment of brainstem spasticity. Case report.
Topics: Adult; Baclofen; Cerebral Infarction; Clonidine; Female; Humans; Medulla Oblongata; Muscle Spasticity; Quadriplegia | 1992 |
Flexor reflex for assessment of common interneurone activity in spasticity.
Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Disorders; Clonidine; Electroacupuncture; Electromyography; Female; Hemiplegia; Humans; Interneurons; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Reaction Time; Reflex | 1992 |
[The effect of muscle relaxants on the function of the vestibulo-ocular reflex arc].
Topics: Adult; Baclofen; Clonidine; Female; Humans; Male; Muscle Relaxants, Central; Reflex, Vestibulo-Ocular | 1990 |
Clonidine reverses methylxanthine-induced potentiation of baclofen antinociception.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Baclofen; Clonidine; Drug Interactions; Male; Neural Pathways; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Theophylline | 1985 |
Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine.
Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Imipramine; Isoproterenol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens | 1989 |
GABAergic agents and clonidine attenuate footshock-induced aggression in mice.
Topics: Aggression; Animals; Baclofen; Clonidine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Reserpine | 1989 |
[Pathogenesis of phantom limb syndrome and its treatment].
Topics: Adult; Aged; Amputation Stumps; Arm; Baclofen; Clonidine; Drug Therapy, Combination; Female; Humans; Hyperesthesia; Leg; Male; Middle Aged; Phantom Limb | 1989 |
Tizanidine vs. baclofen in the treatment of spasticity in patients with multiple sclerosis.
Topics: Baclofen; Clonidine; Drug Tolerance; Humans; Multiple Sclerosis; Muscle Spasticity | 1989 |
[Role of opioid and adrenergic mechanisms in the analgesic action of GABA-positive drugs].
Topics: 4-Aminobutyrate Transaminase; Analgesics; Animals; Baclofen; Clonidine; Drug Tolerance; Female; Male; Morphine; Nociceptors; Pain Measurement; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Valproic Acid | 1988 |
Clonidine reverses baclofen-induced increases in noradrenaline turnover in rat brain.
Topics: alpha-Methyltyrosine; Animals; Baclofen; Brain; Cerebral Cortex; Clonidine; Dopamine; Drug Interactions; Hippocampus; Male; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord; Tyrosine 3-Monooxygenase | 1986 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Myorelaxant effect after intrathecal injection of antispastic drugs in rats.
Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Female; H-Reflex; Injections, Spinal; Male; Midazolam; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Rats; Rats, Mutant Strains; Reflex, Monosynaptic; Time Factors | 1989 |
The effect of presynaptic receptor stimulation on adenosine 3',5'-cyclic monophosphate concentrations in rat cortical synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Baclofen; Cerebral Cortex; Clonidine; Cyclic AMP; gamma-Aminobutyric Acid; Male; Norepinephrine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synaptosomes | 1986 |
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Myenteric Plexus; Receptors, Cholinergic; Receptors, Neurotransmitter; Theophylline | 1987 |
Role of ascending and descending noradrenergic pathways in the antinociceptive effect of baclofen and clonidine.
Topics: Afferent Pathways; Animals; Baclofen; Central Nervous System; Clonidine; Efferent Pathways; Hydroxydopamines; Locus Coeruleus; Male; Norepinephrine; Oxidopamine; Pain; Rats; Rats, Inbred Strains | 1986 |
Tizanidine versus baclofen in the treatment of spasticity in multiple sclerosis patients.
Topics: Adult; Aged; Baclofen; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Muscles | 1988 |
The effect of mouse spinal cord transection on the antinociceptive response to the gamma-aminobutyric acid agonists THIP (4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol) and baclofen.
Topics: Analgesics; Animals; Baclofen; Central Nervous System; Clonidine; Cordotomy; Isoxazoles; Male; Mice; Morphine; Oxazoles; Oxotremorine | 1985 |
Electrophysiological analysis of the mode of action of muscle relaxants in spasticity.
Topics: Baclofen; Clonidine; Diazepam; Electrophysiology; Ethanolamines; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity | 1985 |
Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cats; Clonidine; Drug Interactions; Electroshock; Female; Injections, Spinal; Macaca; Macaca mulatta; Male; Meperidine; Morphine; Naloxone; Narcotics; Pain; Phentolamine; Sensory Thresholds; Spinal Cord | 1981 |
Selective depression of synaptic transmission of spinal neurones in the cat by a new centrally acting muscle relaxant, 5-chloro-4-(2-imidazolin-2-yl-amino)-2, 1, 3-benzothiodazole (DS103-282).
Topics: Amino Acids; Animals; Baclofen; Cats; Clonidine; Female; Male; Muscle Relaxants, Central; Neurons; Reflex; Spinal Cord; Synapses; Synaptic Transmission | 1982 |
Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats.
Topics: Adrenergic Fibers; Animals; Baclofen; Blood-Brain Barrier; Carbon Dioxide; Clonidine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Oxidopamine; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Serum Albumin, Radio-Iodinated | 1983 |
The drug treatment of spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Humans; Muscle Spasticity; Parasympatholytics | 1983 |
Selective antinociceptive effects of tizanidine (DS 103-282), a centrally acting muscle relaxant, on dorsal horn neurones in the feline spinal cord.
Topics: Amino Acids; Analgesics; Animals; Baclofen; Cats; Clonidine; Electric Stimulation; Female; Injections, Intravenous; Iontophoresis; Male; Muscle Relaxants, Central; Naloxone; Neurons; Norepinephrine; Spinal Cord | 1984 |
Self-stimulation response decrement patterns differentiate clonidine, baclofen and dopamine antagonists from drugs causing performance deficit.
Topics: Animals; Baclofen; Clonidine; Conditioning, Operant; Dopamine Antagonists; Extinction, Psychological; Haloperidol; Male; Methocarbamol; Metoclopramide; Prazosin; Rats; Rats, Inbred F344; Receptors, Dopamine; Self Stimulation | 1982 |
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiplegia; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Paralysis; Placebos | 1980 |
Differential effects of K+ channel blockers on antinociception induced by alpha 2-adrenoceptor, GABAB and kappa-opioid receptor agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 4-Aminopyridine; Adrenergic alpha-Agonists; Analgesics; Animals; Baclofen; Clonidine; Drug Interactions; Female; Mice; Mice, Inbred Strains; Nociceptors; Potassium Channels; Pyrrolidines; Receptors, Adrenergic, alpha-2; Receptors, GABA; Receptors, Opioid, kappa; Sulfonylurea Compounds; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
The effects of central myorelaxants on synaptically-evoked primary afferent depolarization in the immature rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Agonists; Animals; Baclofen; Clonidine; Diazepam; Electric Stimulation; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Muscle Relaxants, Central; Nerve Fibers; Neurons, Afferent; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord; Synapses | 1994 |
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Meperidine; Methoxydimethyltryptamines; Neurotransmitter Agents; Yohimbine | 1993 |
Pre-emptive administration of clonidine prevents development of hyperalgesia to mechanical stimuli in a model of mononeuropathy in the rat.
Topics: Analysis of Variance; Animals; Baclofen; Carbamazepine; Clonidine; Disease Models, Animal; Hyperalgesia; Male; Morphine; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve; Time Factors | 1993 |
Effects of excitatory amino acid receptor antagonists on a capsaicin-evoked nociceptive reflex: a comparison with morphine, clonidine and baclofen.
Topics: Animals; Baclofen; Capsaicin; Clonidine; Evoked Potentials; In Vitro Techniques; Morphine; Nociceptors; Rats; Receptors, Amino Acid; Reflex; Spinal Cord | 1993 |
Intrathecal clonidine and baclofen in the management of spasticity and neuropathic pain following spinal cord injury: a case study.
Topics: Adult; Baclofen; Clonidine; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Pain, Intractable; Spinal Cord Injuries; Sympatholytics | 1996 |
Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanisms.
Topics: Analgesics; Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Rats; Respiration; Serotonin | 1996 |
A comparison of the effects of two antispastic drugs, tizanidine and baclofen, on synaptic transmission from muscle spindle afferents to spinal interneurones in cats.
Topics: Afferent Pathways; Animals; Anticonvulsants; Baclofen; Cats; Clonidine; Dose-Response Relationship, Drug; Interneurons; Muscle Spindles; Synaptic Transmission; Time Factors | 1996 |
Local opioid withdrawal in rat single periaqueductal gray neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Clonidine; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Membrane Potentials; Morphine; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Periaqueductal Gray; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance Withdrawal Syndrome; Tetrodotoxin; Time Factors; Valine | 1996 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Contribution of C-fiber afferent nerves and autonomic pathways in the urinary bladder to spinal c-fos expression induced by bladder irritation.
Topics: Acetic Acid; Adrenergic alpha-Agonists; Afferent Pathways; Animals; Autonomic Nervous System; Baclofen; Capsaicin; Clonidine; Female; GABA Agonists; Irritants; Nerve Fibers; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Urinary Bladder | 1998 |
An isobolographic analysis of drug interaction between intrathecal clonidine and baclofen in the formalin test in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Baclofen; Clonidine; Drug Interactions; Formaldehyde; GABA Agonists; Imidazoles; Injections, Spinal; Male; Motor Activity; Pain Threshold; Rats; Rats, Wistar | 1998 |
Nitric oxide modulates spinal antinociceptive effect of clonidine but not that of baclofen in the formalin test in rats.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Arginine; Baclofen; Clonidine; Enzyme Inhibitors; Formaldehyde; GABA Agonists; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement; Postural Balance; Rats; Rats, Wistar | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden].
Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Muscle Spasticity; Spasm | 1999 |
[Current data on bipolar disorders, epilepsy and spasm. 4th Neuro-Forum, Dresden].
Topics: Baclofen; Benzodiazepines; Bipolar Disorder; Clonidine; Epilepsy; Humans; Muscle Relaxants, Central; Paraplegia | 1999 |
Drug interactions and spasticity.
Topics: Adrenergic alpha-Agonists; Antidepressive Agents; Baclofen; Clonidine; Drug Interactions; Humans; Muscle Relaxants, Central; Muscle Spasticity; Serotonin Receptor Agonists | 1999 |
Effects of intrathecal morphine, clonidine and baclofen on allodynia after partial sciatic nerve injury in the rat.
Topics: Analgesics; Analgesics, Opioid; Animals; Baclofen; Clonidine; Cold Temperature; Dose-Response Relationship, Drug; GABA Agonists; Injections, Spinal; Male; Morphine; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1999 |
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Design; GABA Agonists; Mecamylamine; Mice; Molecular Structure; Muscarinic Antagonists; Nicotine; Nootropic Agents; Piperazines; Piracetam; Pyrroles; Scopolamine | 2000 |
Gamma-hydroxybutyric acid and growth hormone secretion studies in rats and dogs.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Baclofen; Clonidine; Dogs; Female; GABA Agonists; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydroxybutyrates; Male; Oligopeptides; Pituitary Gland; Prolactin; Rats | 2000 |
[Pharmacology of spasticity. Does therapy remain in deep sleep?].
Topics: Animals; Baclofen; Botulinum Toxins, Type A; Clonidine; Drug Industry; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Receptors, Adrenergic, alpha-2; Receptors, GABA-B; Research | 2000 |
Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.
Topics: Adenosine; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Clonidine; Female; GABA Agonists; Injections, Spinal; Ischemia; Morphine; Neuralgia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spinal Cord | 2001 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy | 2002 |
A pervasive mechanism for analgesia: activation of GIRK2 channels.
Topics: Analgesia; Analgesics; Animals; Baclofen; Benzoxazines; Clonidine; Crosses, Genetic; Ethanol; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Mutagenesis; Naphthalenes; Nicotine; Oxotremorine; Pain; Polymerase Chain Reaction; Potassium Channels; Potassium Channels, Inwardly Rectifying; Sex Characteristics | 2003 |
Correlation between withdrawal symptoms and medication pump residual volume in patients with implantable SynchroMed pumps.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Baclofen; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Equipment Design; Equipment Failure; Female; Fentanyl; Humans; Hydromorphone; Infusion Pumps, Implantable; Male; Middle Aged; Morphine; Muscle Spasticity; Neurologic Examination; Pain, Intractable; Quality of Life; Retrospective Studies; Substance Withdrawal Syndrome | 2004 |
Drug stability testing to support clinical feasibility investigations for intrathecal baclofen-clonidine admixture.
Topics: Baclofen; Clonidine; Drug Incompatibility; Drug Stability; Drug Therapy, Combination; Humans; Infusion Pumps; Infusions, Parenteral; Muscle Relaxants, Central; Sympatholytics; Time Factors | 2004 |
Involuntary jerking of lower half of the body (spinal myoclonus).
Topics: Baclofen; Clonazepam; Clonidine; Diagnosis, Differential; Humans; Lower Extremity; Middle Aged; Myoclonus; Spinal Cord; Spinal Cord Diseases | 2005 |
Effects of neurotransmitter agonists on electrocortical activity in the rat kainate model of temporal lobe epilepsy and the modulatory action of basic fibroblast growth factor.
Topics: Animals; Baclofen; Clonidine; Electroencephalography; Epilepsy, Temporal Lobe; Fibroblast Growth Factor 2; Functional Laterality; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Muscimol; N-Methylaspartate; Nerve Net; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Signal Transduction; Somatosensory Cortex | 2005 |
Oral baclofen and clonidine for treatment of spasticity in children.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Age Factors; Baclofen; Brain Injuries; Central Nervous System; Cerebral Palsy; Child; Child, Preschool; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; GABA Agonists; Humans; Infant; Male; Muscle Spasticity; Muscle, Skeletal; Retrospective Studies; Time Factors; Treatment Outcome | 2006 |
[Pharmacological treatment of neurogenic detrusor hyperactivity: intrathecal drugs].
Topics: Baclofen; Clonidine; Erectile Dysfunction; Humans; Injections, Spinal; Male; Spinal Cord Injuries; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
Drug treatments for spasticity.
Topics: Administration, Oral; Adult; Alcohols; Algorithms; Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Child; Clonidine; Decision Trees; Humans; Injections, Intramuscular; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Patient Selection; Phenol; Safety; Sclerosing Solutions; Treatment Outcome | 2009 |
Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature.
Topics: Analgesics, Opioid; Baclofen; Cellulitis; Clonidine; Edema; Female; GABA Agonists; Humans; Hydromorphone; Injections, Spinal; Low Back Pain; Middle Aged; Recurrence; Treatment Outcome | 2010 |
Cortical and hippocampal EEG effects of neurotransmitter agonists in spontaneously hypertensive vs. kainate-treated rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Baclofen; Clonidine; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Frontal Lobe; Hippocampus; Hypertension; Kainic Acid; Muscimol; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate | 2011 |
Involvement of hypothalamic periventricular GABAergic nerves in the central pressor response to clonidine in freely-moving conscious rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Bicuculline; Blood Pressure; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Glutamate | 2012 |
Adherence associated with oral medications in the treatment of spasticity.
Topics: Administration, Oral; Adult; Baclofen; Clonidine; Dantrolene; Female; Humans; Male; Medication Adherence; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Retrospective Studies; Young Adult | 2013 |
[Comparative effectiveness of different muscle relaxants in the rehabilitation of post-stroke patients with spasticity].
Topics: Aged; Baclofen; Clonidine; Comparative Effectiveness Research; Dantrolene; Female; Humans; Male; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Recovery of Function; Self Report; Stroke; Stroke Rehabilitation; Tolperisone; Treatment Outcome; Walking | 2013 |
Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Clonidine; Drug Therapy, Combination; Equinus Deformity; Female; Follow-Up Studies; Humans; Male; Muscle Spasticity; Neuromuscular Agents; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2016 |
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption | 2016 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |
Early outcomes after intrathecal baclofen therapy in ambulatory patients with multiple sclerosis.
Topics: Administration, Oral; Aged; Ambulatory Care; Baclofen; Clonidine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Outcome Assessment, Health Care; Pain Measurement; Retrospective Studies; Walking | 2018 |
Trauma-induced adiposis dolorosa (Dercum's disease).
Topics: Accidents, Traffic; Adipose Tissue; Adiposis Dolorosa; Adult; Amitriptyline; Analgesics, Non-Narcotic; Angiomyolipoma; Baclofen; Chronic Pain; Clonidine; Diagnosis, Differential; Humans; Ibuprofen; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed; Upper Extremity | 2018 |
Pharmacological modulation of colorectal distension evoked potentials in conscious rats.
Topics: Animals; Baclofen; Benzoxazines; Cerebral Cortex; Clonidine; Colon; Dilatation, Pathologic; Evoked Potentials; Female; Morpholines; Naphthalenes; Pregabalin; Pyridines; Rats | 2018 |
Pharmacological management of abnormal tone and movement in cerebral palsy.
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Preschool; Clonidine; Diazepam; Dystonia; Female; Humans; Infant; Male; Medical Records; Muscle Relaxants, Central; Muscle Spasticity; Prospective Studies; State Medicine; Trihexyphenidyl; United Kingdom | 2019 |
The use of off-label medications in substance abuse treatment programs.
Topics: Accreditation; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antiemetics; Baclofen; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; Gabapentin; Health Facility Size; Humans; Logistic Models; Off-Label Use; Ondansetron; Practice Patterns, Physicians'; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors; Topiramate; United States; Valproic Acid | 2020 |
Italian consensus on treatment of spasticity in multiple sclerosis.
Topics: Baclofen; Botulinum Toxins; Clonidine; Consensus; Disease Management; Gabapentin; Humans; Injections, Intramuscular; Italy; Multiple Sclerosis; Muscle Spasticity; Quality of Life; Transcutaneous Electric Nerve Stimulation | 2020 |
Identifying Clinically Relevant Drug-Drug Interactions With Methadone and Buprenorphine: A Translational Approach to Signal Detection.
Topics: Baclofen; Bayes Theorem; Benzodiazepines; Buprenorphine; Clonidine; Drug Interactions; Fluconazole; Humans; Methadone; Methocarbamol; Opiate Overdose; Opiate Substitution Treatment; Opioid-Related Disorders; Quetiapine Fumarate; Simvastatin | 2022 |