clonidine has been researched along with azepexole in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (79.49) | 18.7374 |
| 1990's | 6 (15.38) | 18.2507 |
| 2000's | 2 (5.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Jonge, A; Lam, E; Slothorst-Grisdijk, FP; Timmermans, PB; van Meel, JC; van Zwieten, PA | 1 |
| Kobinger, W; Pichler, L | 2 |
| Horváth, E; Jaszlits, L; Rabloczky, G | 1 |
| Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Monassier, L; Tibiriça, E | 1 |
| Koss, MC | 1 |
| Dabiré, H; Mouille, P; Schmitt, H | 1 |
| File, SE; Johnston, AL | 1 |
| Goodlett, CR; Valentino, ML | 1 |
| Giesen-Crouse, E; Imbs, JL; Krieger, JP; Schmidt, M | 1 |
| Lattimer, N; Rhodes, KF; Waterfall, JF | 1 |
| Höglund, AU; Meyerson, BJ | 1 |
| Joly, G; Mouillé, P; Schmitt, H | 1 |
| Harron, DW; Riddell, JG; Shanks, RG | 1 |
| Bergsten, P; Hellman, B | 1 |
| Hillen, FC; van der Laan, JW | 1 |
| Auclair, MC; Schmitt, H | 1 |
| Fondacaro, JD; Kolpak, D; McCafferty, GP | 1 |
| Kobinger, W | 2 |
| Huchet, AM; Huguet, F; Legrand, M; Narcisse, G; Tsoucaris-Kupfer, D | 1 |
| Demichel, P; Gomond, P; Roquebert, J | 1 |
| Dabiré, H; Joly, G; Lucet, B; Mouillé, P; Schmitt, H | 1 |
| Timmermans, PB; Van Brummelen, P; Van Zwieten, PA | 1 |
| Dabiré, H; Joly, G; Mouillé, P; Schmitt, H | 1 |
| Hammer, R; Kobinger, W; Pichler, L | 1 |
| Kobinger, W; Lillie, C; Pichler, L | 1 |
| Timmermans, PB; Van Zwieten, PA | 1 |
| Boyer, JL; Cárdenas, C; García-Sáinz, JA; Posadas, C | 1 |
| Cognie, F; Creuzet, MH; Malek, A; Pontagnier, H; Roquebert, J | 1 |
| Jie, K; Timmermans, PB; van Brummelen, P; van Zwieten, PA; Vermey, P | 1 |
| Paciorek, PM; Pierce, V; Shepperson, NB; Waterfall, JF | 1 |
| Benedikter, L; Mey, T; Middleton, DA | 1 |
| Ishii, K; Kato, R; Yamamoto, S | 1 |
| Bergdahl, A; Edvinsson, L; Feng, QP; Hedner, T; Lu, XR; Sun, XY | 1 |
| Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 1 |
| Edvinsson, L; Feng, Q; Hedner, T; Lu, X; Sun, X | 1 |
| Castillo, C; Castillo, EF; López, RM; Ortíz, CS; Ruíz, A; Vélez, JM | 1 |
| Centurión, D; Cobos-Puc, LE; Márquez-Conde, JA; Monroy-Ordoñez, EB; Sánchez-López, A; Villalón, CM | 1 |
2 review(s) available for clonidine and azepexole
| Article | Year |
|---|---|
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors.
Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine | 1986 |
Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Calcium Channel Blockers; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; Ketanserin; Methyldopa; Muscle, Smooth, Vascular; Phenylacetates; Piperazines; Piperidines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Vascular Resistance | 1984 |
2 trial(s) available for clonidine and azepexole
| Article | Year |
|---|---|
Effects of azepexole and clonidine on baroreceptor mediated reflex bradycardia and physiological tremor in man.
Topics: Adrenergic alpha-Agonists; Adult; Arousal; Azepines; Blood Pressure; Clonidine; Electrocardiography; Heart Rate; Humans; Male; Phenylephrine; Pressoreceptors; Reflex; Tremor | 1985 |
Comparative study of the effect of azepexole and clonidine on blood pressure and pulse rate in normotensive subjects.
Topics: Adult; Azepines; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Oxazoles; Posture; Pulse | 1981 |
35 other study(ies) available for clonidine and azepexole
| Article | Year |
|---|---|
Characterization of alpha-adrenoceptor populations. Quantitative relationships between cardiovascular effects initiated at central and peripheral alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Blood Vessels; Brain; Hemodynamics; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8,-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the "clonidine-type".
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Azepines; Cardiac Output; Cats; Central Nervous System; Clonidine; Decerebrate State; Dogs; Female; Heart Rate; Male; Norepinephrine; Oxazoles; Rats; Reflex; Spinal Cord; Vagotomy | 1977 |
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Heart Rate; Idazoxan; Phentolamine; Phenylephrine; Pyridazines; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Catecholamines; Clonidine; Dioxanes; Electrochemistry; Hemodynamics; Idazoxan; Imidazoline Receptors; Male; Medulla Oblongata; Neurons; Oxazoles; Piperoxan; Rats; Rats, Inbred WKY; Receptors, Drug; Reticular Formation; Rilmenidine; Stereotaxic Techniques; Yohimbine | 1991 |
Characterization of adrenoceptor subtypes in cat cutaneous vasculature.
Topics: Animals; Azepines; Cats; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Male; Norepinephrine; Prazosin; Receptors, Adrenergic; Regional Blood Flow; Skin; Vasoconstriction | 1990 |
(Imidazolinyl-2)-2-benzodioxane 1-4 (idazoxan) and its stereoisomers, new alpha 2-antagonists.
Topics: Animals; Azepines; Chickens; Clonidine; Dioxanes; Dioxins; Heart Rate; Idazoxan; Imidazoles; Male; Mice; Muscle Contraction; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 1985 |
Yohimbine's anxiogenic action: evidence for noradrenergic and dopaminergic sites.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Animals; Anxiety; Apomorphine; Azepines; Benzazepines; Clonidine; Dopamine Agents; Ergolines; Guanfacine; Guanidines; Learning; Male; Norepinephrine; Phenylacetates; Phenylephrine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Yohimbine | 1989 |
Differential effects of clonidine, B-HT 933 and B-HT 920 in immature rat pups.
Topics: Animals; Azepines; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Haloperidol; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter | 1987 |
Characterisation of the alpha-adrenoceptors of the rat renal vascular bed.
Topics: Animals; Azepines; Clonidine; Dopamine; In Vitro Techniques; Kidney; Male; Nordefrin; Perfusion; Phenylephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vascular Resistance; Yohimbine | 1987 |
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine | 1985 |
Increased investigative activity after presynaptic dopaminergic stimulation measured by a fixed-interval recording procedure.
Topics: Adrenergic alpha-Agonists; alpha-Methyltyrosine; Animals; Apomorphine; Azepines; Clonidine; Drug Interactions; Exploratory Behavior; Haloperidol; Male; Methyltyrosines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Stimulation, Chemical; Yohimbine | 1985 |
Antagonistic effects of S9871 or (imidazolinyl-2)-2-dihydro 2,3 benzofurane and its stereoisomers on some central and peripheral actions of alpha 2-agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzofurans; Blood Pressure; Cardiovascular System; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Hypnotics and Sedatives; Idazoxan; Injections, Intraventricular; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Stereoisomerism | 1985 |
Unmasking of the inhibitory action of glucose on insulin release after alpha 2-adrenergic activation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Glucose; Idazoxan; Insulin; Islets of Langerhans; Mice; Mice, Obese | 1986 |
The potentiation of morphine-withdrawal jumping by clonidine is antagonized by m-chlorophenylpiperazine and not by haloperidol.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Behavior, Animal; Clonidine; Dopamine Antagonists; Drug Synergism; Haloperidol; Male; Morphine; Piperazines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1986 |
Antagonism by E. coli endotoxin of some cardiovascular effects induced in the rat by two alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Diltiazem; Endotoxins; Escherichia coli; Heart Rate; Male; Rats; Rats, Inbred Strains | 1987 |
Selective alpha-2 adrenoceptor agonists alter fluid and electrolyte transport in mammalian small intestine.
Topics: 16,16-Dimethylprostaglandin E2; Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Intestine, Small; Male; Rabbits; Yohimbine | 1988 |
Interaction between central alpha 1- and alpha 2-adrenoceptors on sympathetic tone in rats.
Topics: Animals; Azepines; Brain; Clonidine; Guanfacine; Guanidines; Heart Rate; Injections, Intraventricular; Male; Phenylacetates; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vagotomy | 1986 |
alpha 1-adrenoceptor blockade by alpha 2-adrenoceptor agonists in the isolated perfused hindquarter of rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; In Vitro Techniques; Male; Methoxamine; Oxazoles; Perfusion; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiazoles; Vasoconstriction | 1981 |
alpha-Adrenoceptor blocking properties of raubasine in pithed rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Electric Stimulation; Heart Rate; Male; Phenylephrine; Rats; Rats, Inbred Strains; Secologanin Tryptamine Alkaloids; Spinal Cord; Yohimbine | 1982 |
Central blood pressure regulation. Involvement of presynaptic or postsynaptic, alpha 1- or alpha 2-adrenoceptors?
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Cats; Clonidine; Dogs; Heart Rate; Medulla Oblongata; Oxymetazoline; Piperoxan; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses | 1983 |
Pre- and postsynaptic alpha-adrenoceptor blocking properties of a new dihydrobenzofurane derivative (imidazolinyl-2)-2-dihydro 2,3 benzofurane (S 9871) and its stereoisomers in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Benzofurans; Blood Pressure; Clonidine; Drug Interactions; Electric Stimulation; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Rats; Rats, Inbred Strains; Stereoisomerism; Vas Deferens | 1984 |
Peripheral postsynaptic alpha-adrenoceptor blocking properties of some new dihydrobenzofurane and imidazoline derivatives in pithed rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzofurans; Blood Pressure; Clonidine; Drug Interactions; Imidazoles; Male; Phenethylamines; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter | 1984 |
Binding of an imidazolidine (clonidine), an oxazoloazepin (B-HT 933) and a thiazoloazepin (B-HT 920) to rat brain alpha-adrenoceptors and relation to cardiovascular effects.
Topics: Animals; Azepines; Binding Sites; Binding, Competitive; Blood Pressure; Brain; Clonidine; Heart Rate; Kinetics; Male; Oxazoles; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiazoles | 1980 |
Central cardiovascular alpha-adrenoceptors. Relation to peripheral receptors.
Topics: Animals; Azepines; Blood Pressure; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Male; Methoxamine; Norepinephrine; Oxazoles; Perfusion; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiazoles; Vagotomy | 1980 |
Postsynaptic alpha 1- and alpha 2-adrenoceptors in the circulatory system of the pithed rat: selective stimulation of the alpha 2-type by B-HT 933.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Oxazoles; Phentolamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Vasomotor System; Yohimbine | 1980 |
"Pertussis toxin induces tachycardia and impairs the increase in blood pressure produced by alpha 2-adrenergic agonists".
Topics: Animals; Azepines; Bacterial Toxins; Blood Pressure; Bordetella pertussis; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Methoxamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tachycardia | 1983 |
Alpha 1- and alpha 2-adrenoceptor selectivity of moxisylyte (thymoxamine) and its metabolites in the pithed rat.
Topics: Animals; Azepines; Blood Pressure; Clonidine; Electric Stimulation; Heart Rate; Male; Moxisylyte; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord | 1983 |
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Topics: Adult; Azepines; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Doxazosin; Female; Guanfacine; Guanidines; Heart Rate; Humans; Male; Methoxamine; Muscle, Smooth, Vascular; Phenylacetates; Prazosin; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1984 |
An investigation into the selectivity of a novel series of benzoquinolizines for alpha 2-adrenoceptors in vivo.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Action Potentials; Animals; Azepines; Chlorisondamine; Clonidine; Female; Indoramin; Methoxamine; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Development of clonidine-tolerance in the rat vas deferens: cross tolerance to other presynaptic inhibitory agents.
Topics: Adenosine; Animals; Azepines; Clonidine; Drug Tolerance; Endorphins; Evoked Potentials; Male; Methoxamine; Muscle Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Sympathomimetics; Vas Deferens | 1982 |
Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dose-Response Relationship, Drug; Heart Failure; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Male; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure.
Topics: Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Autonomic Fibers, Preganglionic; Azepines; Blood Pressure; Cardiac Output; Catecholamines; Clonidine; Decerebrate State; Electric Stimulation; Heart Failure; Male; Myocardial Infarction; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y | 1999 |
Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Azepines; Brimonidine Tartrate; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Methoxamine; Nitric Oxide; Phenylephrine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin; Vasoconstrictor Agents; Vasodilation; Yohimbine | 2006 |
Evidence that some imidazoline derivatives inhibit peripherally the vasopressor sympathetic outflow in pithed rats.
Topics: Adrenergic alpha-Agonists; Agmatine; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Blood Vessels; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Imidazoles; Imidazoline Receptors; Imidazolines; Injections, Intravenous; Male; Methoxamine; Rats; Rats, Wistar; Sympathetic Nervous System; Vasomotor System | 2008 |