clonidine has been researched along with atropine in 179 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (48.60) | 18.7374 |
| 1990's | 53 (29.61) | 18.2507 |
| 2000's | 24 (13.41) | 29.6817 |
| 2010's | 14 (7.82) | 24.3611 |
| 2020's | 1 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Kobinger, W; Pichler, L | 1 |
| Nedergaard, OA; Schrold, J | 1 |
| Bogaert, A; Bogaert, PP; DeWilde, A; Reneman, RS; Wellens, D; Wouters, L | 1 |
| Paalzow, G; Paalzow, L | 1 |
| Lisciani, R; Silvestrini, B | 1 |
| Bartmus, D; Dinnendahl, V; Gumulka, SW; Schönhöfer, PS; Stock, K | 1 |
| Borowski, E; Gross, G; Schümann, HJ | 1 |
| Gala, RR; Lawson, DM | 1 |
| Hughes, MJ; Light, KE | 1 |
| Drujan, BD; Negishi, K | 1 |
| Cavalheiro, EA; Izquierdo, I | 1 |
| Chen, CS; Ozawa, H; Uematsu, T; Watanabe, H | 1 |
| Gaul, SL; Sweet, CS | 1 |
| Kawasaki, H; Razzak, A; Ueki, S | 1 |
| Dhawan, BN; Gulati, K; Srimal, RC | 1 |
| Lipsitz, DJ; Pai, GS | 1 |
| Gennery, BA; Poyner, TF; Vasey, RH | 1 |
| Waldeck, B | 2 |
| Contin, M; Cortelli, P; Lugaresi, A; Lugaresi, E; Parchi, P; Pasquali, R; Sforza, E | 1 |
| Jhamandas, K; Penning, DH | 1 |
| Pásztélyi, Z; Simon, G; Zelles, T | 1 |
| Goyagi, T; Ikemura, A; Iwai, R; Kimura, T; Nishikawa, T; Sakaguchi, M | 1 |
| Niida, H; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Arce, V; Devesa, J; Diaz, MJ; Lima, L; Tresguerres, JA | 1 |
| Carlsson, A; Carlsson, M; Svensson, A | 1 |
| Stephen, PM; Thomas, GP | 1 |
| Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P | 1 |
| Dai, S; Wang, Y | 1 |
| Maggi, CA | 1 |
| Dohi, S; Nishikawa, T | 1 |
| Bédard, PJ; Boucher, R; Gomez-Mancilla, B | 1 |
| Henretig, FM; Torrey, SB; Wiley, CC; Wiley, JF | 1 |
| Liu, WF | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Reis, CC | 1 |
| Luzhnikov, EA; Savina, AS; Sukhodolova, GA | 1 |
| Carlsson, M; Svensson, A | 2 |
| Cavero, I; Thiry, C | 1 |
| Burton, MD; Johnson, DC; Kazemi, H | 1 |
| Jumblatt, JE; Ohia, SE | 1 |
| Fiser, DH; Moss, MM; Walker, W | 1 |
| Mehta, VL; Prabhu, S; Valecha, N | 1 |
| Chahl, LA | 1 |
| Lang, U; Walland, A | 1 |
| Carlsson, A; Carlsson, M | 1 |
| Hollingsworth, PJ; Smith, CB | 1 |
| Gillberg, PG; Gordh, T; Hartvig, P; Jansson, I; Post, C | 1 |
| Lang, U; Streller, I; Walland, A | 1 |
| Aronstam, RS; Buccafusco, JJ | 2 |
| Kitazawa, T; Kondo, H; Temma, K | 2 |
| Verrier, RL | 1 |
| Varma, DR; Yue, TL | 1 |
| Kaada, B | 1 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Del Soldato, P | 1 |
| Fozard, JR; Ramage, AG | 1 |
| Andersson, RG; Grundström, N | 1 |
| Konno, F; Kusunoki, M; Takayanagi, I | 1 |
| Ahrens, FA; Panichkriangkrai, W | 2 |
| Aronstam, RS; Buccafusco, JJ; Graham, JH | 1 |
| Szilagyi, JE | 1 |
| Kaneda, H; Kaneto, H; Kawatani, S | 1 |
| Chiba, S; Furukawa, Y; Ogiwara, Y; Takeda, M | 1 |
| Fondacaro, JD; Henderson, LS; Sjöqvist, A | 1 |
| Imai, Y; Johnston, CI; Nolan, PL | 1 |
| Lakić, N; Manev, H; Pericić, D | 1 |
| Aronstam, RS; Buccafusco, JJ; Molloy, AG | 1 |
| Bueno, L; Primi, MP | 1 |
| Kanaoka, R; Maeda-Hagiwara, M; Watanabe, H; Watanabe, K | 1 |
| Hageman, GR; James, TN; Neely, BH; Urthaler, F | 1 |
| Ekdahl, A; Olsson, OA | 1 |
| Faucon, G; Lakhal, M; Lièvre, M; Morin, MH | 1 |
| Kobinger, W; Walland, A | 2 |
| Delbarre, B; Schmitt, H | 1 |
| Cocchi, D; Jalanbo, H; Mantegazza, P; Müller, EE; Peruzzi, G; Udeschini, G | 1 |
| Laubie, M; Schmitt, H | 1 |
| Combre, A; Cosnier, D; Delort, P; Duchêne-Marullaz, P; Lapalus, P | 1 |
| Papeschi, R | 1 |
| Boucher, M; Duchene-Marullaz, P; Lapalus, P; Lavarenne, J; Mongheal, Y | 1 |
| Day, MD; Roach, AG | 1 |
| Antonaccio, MJ; Robson, RD | 1 |
| Ohkusu, Y | 1 |
| Beubler, E; Bukhave, K; Rask-Madsen, J | 1 |
| Klepper, MS; Rush, BD; Ruwart, MJ | 1 |
| James, TN; Primm, RK; Urthaler, F | 1 |
| Bartholini, G; Scatton, B | 1 |
| Depoortere, H; M'Harzi, M; Monmaur, P | 1 |
| Belleau, B; Benfey, BG; Melchiorre, C | 1 |
| Olsson, JM; Pruitt, AW | 1 |
| Girardot, MN; Koss, MC | 1 |
| Guan, YY; Ma, CG; Xu, SY | 1 |
| Becker, H; Dietz, R; Ganten, D; Lang, RE; Rettig, R; Schömig, A; Schwab, NA; Unger, T | 1 |
| Leu, SY; Lin, MT; Shian, LR | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 1 |
| Cabezas-Cerrato, J; Cabranes, JA; Casanueva, FF; Fernandez-Cruz, A; Villanueva, L | 1 |
| Bloor, BC; Flacke, JW; Flacke, WE; Olewine, S | 1 |
| Advenier, C; Floch, A; Mallard, B | 1 |
| Pappas, BA; Robinson, TE; Vanderwolf, CH | 1 |
| Anderson, RJ; Crumpler, CP; Hart, GR; Lerman, MJ | 1 |
| Bentley, GA; McLennan, PL | 1 |
| Millar, JS; Williams, EM | 1 |
| Baum, T; Becker, FT | 2 |
| Lipman, JJ; Spencer, PS | 1 |
| Ehlert, FJ; Roeske, WR; Smit, MH; Yamamura, HI; Yamamura, S | 1 |
| Chen, IJ; Chen, IS; Chen, SJ; Lo, YC; Wu, BN; Yeh, JL | 1 |
| Nakamura, K; Okuma, Y; Osumi, Y; Yokotani, K | 1 |
| Adachi, M; Manita, S; Matsuda, T; Shigenobu, K; Tanaka, H | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H | 1 |
| Matsukawa, K; Mitchell, JH; Wall, PT; Wilson, LB | 1 |
| Dehpour, AR; Delfan, A; Mortazavi, SR; Mousavizadeh, K | 1 |
| Derksen, FJ; Robinson, NE; Wang, ZW; Yu, MF | 1 |
| Ishii, A; Karasawa, A; Kishibayashi, N; Tomaru, A | 1 |
| Baranyi, M; Mike, A; Milusheva, E; Vizi, ES; Zelles, T | 1 |
| Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Ford, GA; James, OF | 1 |
| Naguib, M; Yaksh, TL | 1 |
| Nott, MW; Rand, MJ; Thaina, P | 1 |
| Bédard, PJ; Gomez-Mancilla, B | 1 |
| Hatano, A; Koizumi, T; Komeyama, T; Takahashi, H; Takeda, M; Tamaki, M; Tsutsui, T | 1 |
| Amabeoku, GJ | 1 |
| Casanueva, FF; Dieguez, C; Muruais, J; Peñalva, A | 1 |
| Grosvenor, CE; Kacsóh, B; Tóth, BE | 1 |
| Hughes, IE; Large, BJ; Sadraei, H | 1 |
| Chang, KC; Hahn, KH | 1 |
| Boucher, M; Chapuy, E; Chassaing, C; Dubar, M | 1 |
| Coupar, IM; Liu, L | 1 |
| Ishizuka, I; Kakoi, H; Kawasaki, J; Kawazoe, T; Kodaka, M; Miyao, H; Okamoto, Y | 1 |
| Kimura, T; Nishikawa, T; Tanaka, M | 1 |
| Komatsu, T; Shimada, Y; Taki, K; Yano, K; Yokota, S | 1 |
| Hushcha, TO; Luik, AI; Mischenko, NI; Mogilevich, SE | 1 |
| Kimura, K; Kise, M; Masui, Y; Niida, H; Shirouchi, Y; Tajima, K; Ueda, F; Yamamoto, O | 1 |
| Angus, JA; Serone, AP | 1 |
| Babaie, A; Etminani, A; Gharib, B; Homayoun, H; Zarrindast, MR | 1 |
| Ho, JW; Leung, YK | 1 |
| Sivagnanam, S | 1 |
| Fok, M; Stein, RB | 1 |
| Cometa, MF; Luzi, A; Palmery, M | 1 |
| Conklin, D; Eisenach, JC; Paqueron, X | 1 |
| Michael, JB; Sztajnkrycer, MD | 1 |
| Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
| Ando, S; Harasawa, I; Honda, K; Kamiya, HO; Koga, K; Takano, Y | 1 |
| Goyagi, T; Minamizono, T; Nishikawa, T; Tanaka, M | 1 |
| Dkhar, SA; Naveen, AT; Peddyreddy, MK; Ramaswamy, S; Shewade, DG | 1 |
| Bayati, A; Mattsson, H; Nielsen, MA | 1 |
| Doihara, H; Ito, H; Kawabata-Shoda, E; Kojima, R; Nozawa, K; Yokoyama, T | 1 |
| Carabalona, R; Castiglioni, P; Cividjian, A; Di Rienzo, M; Parati, G; Quintin, L | 1 |
| Eisenach, JC; Gutierrez, S; Hayashida, K; Peters, CM | 1 |
| Feng, ZH; Li, XY; Liu, L; Mei, SH; Wang, M; Wang, Y; Wang, YJ; Zuo, ZX | 1 |
| Eisenach, JC; Hayashida, KI; Kimura, M | 1 |
| Iyengar, AR; Pande, AH | 1 |
| Heppell, SP; Isbister, GK; Page, CB; Ryan, NM | 1 |
| Castiglioni, P; Cividjian, A; Karemaker, JM; Quintin, L; Settels, JJ; Toader, E; Wesseling, KH; Westerhof, BE | 1 |
| Bharucha, AE; Feuerhak, K; Sharma, M; Zinsmeister, AR | 1 |
| Carr, BJ; Hollenberg, MD; Mihara, K; Nathanson, NM; Ramachandran, R; Saifeddine, M; Stell, WK | 1 |
| Downes, MA; Duong, C; Isbister, GK; Lovett, C | 1 |
4 review(s) available for clonidine and atropine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clonidine overdose: report of six cases and review of the literature.
Topics: Adolescent; Adult; Atropine; Bradycardia; Child, Preschool; Clonidine; Dopamine; Female; Humans; Hypotension; Male; Middle Aged; Pupil; Respiration Disorders; Sensation; Substance-Related Disorders; Tolazoline | 1981 |
Deadly pediatric poisons: nine common agents that kill at low doses.
Topics: Alcohols; Algorithms; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antidotes; Antihypertensive Agents; Atropine; Calcium Channel Blockers; Camphor; Child; Child, Preschool; Clonidine; Decision Trees; Diagnosis, Differential; Diphenoxylate; Drug Combinations; Emergency Medicine; Emergency Treatment; Gastrointestinal Agents; Humans; Infant; Pediatrics; Poisoning; Salicylates; Sulfonylurea Compounds; United States | 2004 |
Organophosphate-Hydrolyzing Enzymes as First-Line of Defence Against Nerve Agent-Poisoning: Perspectives and the Road Ahead.
Topics: Antidotes; Atropine; Chemical Warfare; Clonidine; Diazepam; Excitatory Amino Acid Antagonists; Humans; Hydrolases; Hydrolysis; Nerve Agents; Organophosphates; Oximes; Purinergic P1 Receptor Agonists; Pyridostigmine Bromide; Renal Dialysis | 2016 |
9 trial(s) available for clonidine and atropine
| Article | Year |
|---|---|
[The effects of preanesthetic oral clonidine upon heart rate response to intravenous atropine in patients during general anesthesia].
Topics: Administration, Oral; Adolescent; Adult; Anesthesia, General; Atropine; Clonidine; Heart Rate; Humans; Injections, Intravenous; Middle Aged | 1992 |
Evidence that alpha 2-adrenergic pathways play a major role in growth hormone (GH) neuroregulation: alpha 2-adrenergic agonism counteracts the inhibitory effect of muscarinic cholinergic receptor blockade on the GH response to GH-releasing hormone, while
Topics: Adult; Atropine; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Homeostasis; Humans; Hypothalamus; Kinetics; Male; Pyridostigmine Bromide; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Somatostatin; Time Factors; Yohimbine | 1991 |
Oral clonidine blunts the heart rate response to intravenous atropine in humans.
Topics: Administration, Oral; Adolescent; Adult; Aged; Atropine; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Humans; Infusions, Intravenous; Middle Aged; Preanesthetic Medication | 1991 |
Oral clonidine premedication blunts the heart rate response to intravenous atropine in awake children.
Topics: Administration, Oral; Adolescent; Atropine; Child; Clonidine; Heart Rate; Humans; Infusions, Intravenous; Preanesthetic Medication; Wakefulness | 1995 |
[The effects of premedication on induction doses of propofol and hemodynamic responses during induction].
Topics: Adult; Atropine; Clonidine; Diazepam; Drug Interactions; Female; Hemodynamics; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Preanesthetic Medication; Propofol | 1997 |
Effects of oral clonidine on heart rate changes after neostigmine-atropine administration.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adult; Anesthesia, General; Atropine; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Male; Middle Aged; Neostigmine; Preanesthetic Medication | 1998 |
Effect of oral clonidine premedication on hemodynamic response during sedated nasal fiberoptic intubation.
Topics: Administration, Oral; Adult; Aged; Atropine; Clonidine; Conscious Sedation; Fiber Optic Technology; Hemodynamics; Humans; Hydroxyzine; Intubation, Gastrointestinal; Middle Aged; Preanesthetic Medication | 1998 |
[Effects of oral clonidine premedication on the heart rate response to intravenous atropine during propofol anesthesia].
Topics: Administration, Oral; Adult; Analgesics; Anesthetics, Intravenous; Atropine; Clonidine; Female; Heart Rate; Humans; Injections, Intravenous; Male; Preanesthetic Medication; Propofol | 2005 |
A pharmacological challenge predicts reversible rectal sensorimotor dysfunctions in women with fecal incontinence.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Atropine; Clonidine; Double-Blind Method; Fecal Incontinence; Female; Humans; Manometry; Middle Aged; Muscarinic Antagonists; Muscle Tonus; Rectum; Sensory Thresholds | 2018 |
166 other study(ies) available for clonidine and atropine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine | 1975 |
Presynaptic muscarinic and alpha-adrenergic receptor blocking effect of atropine on the noradrenergic neurones of the rabbit pulmonary artery.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Drug Interactions; Electric Stimulation; Neurons; Norepinephrine; Phentolamine; Pulmonary Artery; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic | 1979 |
Proceedings: The effects of hypothalamic and reflexogenic hypertension on renal and femoral circulation.
Topics: Animals; Antihypertensive Agents; Atropine; Benzimidazoles; Blood Flow Velocity; Carotid Sinus; Clonidine; Dioxanes; Dogs; Electric Stimulation; Femoral Artery; Hypertension; Hypothalamus; Kidney; Piperidines; Pressoreceptors; Vagotomy | 1975 |
Clonidine antinociceptive activity: effects of drugs influencing central monoaminergic and cholinergic mechanisms in the rat.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Atropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Chlorpromazine; Clonidine; Electroshock; Fenclonine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Naloxone; Parasympathetic Nervous System; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Sympathetic Nervous System; Vocalization, Animal; Yohimbine | 1976 |
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice, Inbred Strains; Nicotine; Oxotremorine; Parkinson Disease, Secondary; Phenoxybenzamine; Piloerection; Pyrilamine; Rabbits; Salivation; Sympathetic Nervous System; Trazodone; Tremor | 1976 |
On the mode of action of clonidine: relationship between effects on behaviour and cyclic nucleotide content in mouse brain.
Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Brain Chemistry; Clonidine; Cyclic GMP; Exophthalmos; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Piloerection; Reserpine; Scopolamine; Time Factors | 1977 |
Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism.
Topics: Animals; Atropine; Blood Pressure; Bupranolol; Clonidine; Disease Models, Animal; Electric Stimulation; Heart Rate; Hypothyroidism; Isoproterenol; Male; Norepinephrine; Phenylephrine; Propylthiouracil; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Spinal Cord; Tubocurarine | 1979 |
The influence of adrenergic, dopaminergic, cholinergic and serotoninergic drugs on plasma prolactin levels in ovariectomized, estrogen-treated rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Arecoline; Atropine; Castration; Clonidine; Dibenzothiepins; Dopamine; Estradiol; Female; Isoproterenol; Mecamylamine; Nicotine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Piperazines; Prolactin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Sulfides | 1975 |
Depressive action of clonidine on guinea pig and rabbit atrial pairs.
Topics: Animals; Atropine; Clonidine; Depression, Chemical; Drug Interactions; Guinea Pigs; Heart Rate; In Vitro Techniques; Metiamide; Rabbits; Time Factors | 1979 |
Similarities in effects of acetylcholine and dopamine on horizontal cells in the fish retina.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Cholinesterase Inhibitors; Clonidine; Dopamine; Fishes; Hexamethonium Compounds; Membrane Potentials; Phentolamine; Photic Stimulation; Photoreceptor Cells; Physostigmine; Retina | 1979 |
Three main factors in rat shuttle behavior: their pharmacology and sequential entry in operation during a two-way avoidance session.
Topics: Animals; Apomorphine; Atropine; Atropine Derivatives; Avoidance Learning; Clonidine; Conditioning, Classical; Conditioning, Operant; Drive; Female; Haloperidol; Male; Nicotine; Phenoxybenzamine; Physostigmine; Rats | 1976 |
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipramine; Drug Synergism; Guanethidine; Heart Rate; Hexamethonium Compounds; Injections, Intravenous; Injections, Subcutaneous; Male; Phentolamine; Rats; Reserpine | 1977 |
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation | 1977 |
Cardiovascular changes induced by large doses of clonidine in mice.
Topics: Animals; Atropine; Blood Pressure; Clonidine; Dopamine; Heart Rate; Male; Mice; Phentolamine; Propranolol; Vagotomy | 1977 |
On the mechanism of central hypotensive action of clonidine.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Clonidine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Glycine; Heart Rate; Hemicholinium 3; Injections, Intravenous; Male; Medulla Oblongata; Parasympathetic Nervous System | 1977 |
Clonidine poisoning.
Topics: Atropine; Blood Pressure; Bradycardia; Child, Preschool; Clonidine; Coma; Heart Rate; Humans; Hypothermia; Male; Poisoning; Reflex; Respiration | 1976 |
Management in cases of clonidine overdosage.
Topics: Adolescent; Atropine; Blood Pressure; Bradycardia; Clonidine; Diuresis; Female; Humans; Hypotension; Poisoning; Substance-Related Disorders; Tolazoline | 1976 |
Effect of caffeine on locomotor activity and central catecholamine mechanisms: a study with special reference to drug interaction.
Topics: Animals; Atropine; Barbiturates; Caffeine; Catecholamines; Clonidine; Dihydroxyphenylalanine; Drug Interactions; Drug Synergism; Ethanol; Female; Mice; Motor Activity; Reserpine; Time Factors | 1975 |
Isolated failure of noradrenergic transmission in a case with orthostatic hypotension and hyperactivity of gastro-colic reflex.
Topics: Adult; Atropine; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Colon; Defecation; Edrophonium; Epinephrine; Heart Rate; Humans; Hypotension, Orthostatic; Male; Norepinephrine; Reference Values; Stomach; Synaptic Transmission; Tyramine; Valsalva Maneuver; Yohimbine | 1992 |
Yohimbine-precipitated clonidine withdrawal: an experimental model of the antihypertensive drug withdrawal syndrome.
Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Central Nervous System; Choline; Clonidine; Ganglia, Sympathetic; Ganglionic Blockers; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Injections, Intraventricular; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Yohimbine | 1992 |
Cross reactivity among the ligands of the 7 helix family.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Binding, Competitive; Brain; Clonidine; Cross Reactions; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Isoproterenol; Ligands; Membranes; Quinuclidinyl Benzilate; Rats; Receptors, Cell Surface | 1992 |
Vagally mediated acid hypersecretion and lesion formation in anesthetized rat under hypothermic conditions.
Topics: Animals; Atropine; Carbachol; Clonidine; Ganglionic Blockers; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Hypothermia; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Thyrotropin-Releasing Hormone; Vagotomy | 1991 |
Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Biperiden; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methyldopa; Mice; Mice, Neurologic Mutants; Motor Activity; N-Methylaspartate; Parasympatholytics; Parkinson Disease; Piperazines | 1991 |
Protective action of clonidine against the arrhythmogenic and lethal effects of ouabain in guinea-pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Blood Pressure; Cardiac Pacing, Artificial; Clonidine; Drug Interactions; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Infusions, Intravenous; Male; Ouabain | 1991 |
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine | 1990 |
Naloxone-induced cardiovascular depression in rats that had received chronic morphine-treatment.
Topics: Anesthesia; Animals; Arteries; Atropine; Blood Pressure; Cardiac Complexes, Premature; Clonidine; Heart; Hemodynamics; In Vitro Techniques; Male; Morphine; Muscle, Smooth, Vascular; Naloxone; Rats; Rats, Inbred Strains; Tail; Yohimbine | 1991 |
Omega conotoxin and prejunctional modulation of the biphasic response of the rat isolated urinary bladder to single pulse electrical field stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Clonidine; Drug Interactions; Drug Synergism; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Physostigmine; Rats; Rats, Inbred Strains; Urinary Bladder | 1991 |
Effect of clonidine and atropine on rest tremor in the MPTP monkey model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Clonidine; Disease Models, Animal; Electromyography; Female; Macaca fascicularis; Muscles; Parkinson Disease, Secondary; Time Factors; Tremor | 1991 |
Clonidine poisoning in young children.
Topics: Atropine; Bradycardia; Charcoal; Child; Child, Preschool; Clonidine; Female; Gastric Lavage; Heart Rate; Humans; Infant; Ipecac; Male; Naloxone; Respiration, Artificial | 1990 |
A symptomatological assessment of organophosphate-induced lethality in mice: comparison of atropine and clonidine protection.
Topics: Animals; Atropine; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Organophosphate Poisoning; Organophosphorus Compounds; Poisoning; Sarin | 1991 |
Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus.
Topics: Animals; Atropine; Clonidine; Electric Stimulation; Epilepsy; Hippocampus; Male; Parasympathomimetics; Pilocarpine; Propranolol; Pyramidal Tracts; Rats; Rats, Inbred Strains; Reserpine; Seizures; Sympathomimetics | 1991 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Practolol; Prazosin; Yohimbine | 1991 |
[Acute klofelin poisoning].
Topics: Acute Disease; Adolescent; Adult; Antidotes; Atropine; Benzilates; Bradycardia; Child, Preschool; Choline; Clonidine; Gastric Lavage; Humans; Infant; Middle Aged | 1990 |
The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice.
Topics: Animals; Atropine; Clonidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; N-Methylaspartate; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate | 1990 |
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems.
Topics: Animals; Aspartic Acid; Atropine; Biogenic Monoamines; Clonidine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Glutamates; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission | 1990 |
Validation of a novel technique allowing assessment of the functional role of cardiac prejunctional receptors in the rat.
Topics: Animals; Atropine; Blood Pressure; Clonidine; Electric Stimulation; Heart; Heart Rate; Male; Neuromuscular Junction; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord; Thymus Gland | 1990 |
Adrenergic and cholinergic interaction in central ventilatory control.
Topics: Acetylcholine; Animals; Atropine; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Medulla Oblongata; Propanolamines; Receptors, Adrenergic; Receptors, Cholinergic; Respiration; Respiratory Center; Second Messenger Systems; Yohimbine | 1990 |
Inhibitory effects of neuropeptide Y on sympathetic neurotransmission in the rabbit iris-ciliary body.
Topics: Animals; Atropine; Carbachol; Ciliary Body; Clonidine; Drug Interactions; Female; Iris; Male; Neuropeptide Y; Norepinephrine; Pancreatic Polypeptide; Peptide YY; Peptides; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 1990 |
Critical care for clonidine poisoning in toddlers.
Topics: Atropine; Child, Preschool; Clonidine; Consciousness; Critical Care; Dopamine; Dose-Response Relationship, Drug; Female; Fluid Therapy; Humans; Infant; Length of Stay; Male; Naloxone; Poisoning; Resuscitation; Retrospective Studies | 1990 |
Influence of clonidine, methyldopa and propranolol on acute toxicity of fenitrothion in mice.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Fenitrothion; Male; Methyldopa; Mice; Propranolol | 1990 |
The properties of the clonidine withdrawal response of guinea-pig isolated ileum.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Enkephalin, Methionine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Norepinephrine; Phentolamine; Substance P; Substance Withdrawal Syndrome; Yohimbine | 1985 |
Alinidine reverses the descending staircase of isolated rat atria by an antimuscarinic action.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Clonidine; Female; Guinea Pigs; Heart; In Vitro Techniques; Ipratropium; Isometric Contraction; Male; Oxotremorine; Papillary Muscles; Parasympatholytics; Rats; Rats, Inbred Strains | 1989 |
Marked locomotor stimulation in monoamine-depleted mice following treatment with atropine in combination with clonidine.
Topics: Animals; Atropine; Biogenic Monoamines; Clonidine; Drug Interactions; Male; Mice; Motor Activity; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Reserpine | 1989 |
Effects of muscarinic receptor agonists and antagonists on alpha 2-adrenoceptors in rat brain.
Topics: Animals; Atropine; Atropine Derivatives; Brain; Clonidine; Male; N-Methylscopolamine; Neurons; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Time Factors | 1989 |
Interactions between noradrenergic and cholinergic mechanisms involved in spinal nociceptive processing.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Hydroxydopamines; Male; Neostigmine; Nociceptors; Oxidopamine; Pain Measurement; Parasympathetic Nervous System; Parasympathomimetics; Phentolamine; Physostigmine; Rats; Rats, Inbred Strains; Spinal Cord; Sympathetic Nervous System | 1989 |
Alinidine antagonizes the myocardial effects of adenosine.
Topics: Action Potentials; Adenosine; Animals; Atropine; Cardiovascular Agents; Clonidine; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Rats | 1989 |
Adrenergic agonists protect against soman, an irreversible acetylcholinesterase inhibitor.
Topics: Animals; Atropine; Clonidine; Drug Synergism; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Receptors, Adrenergic, alpha; Soman; Sympathomimetics | 1987 |
Presynaptic alpha-adrenoceptor mediated inhibition of the neurogenic cholinergic contraction in the isolated intestinal bulb of the carp (Cyprinus carpio).
Topics: Animals; Atropine; Carps; Catecholamines; Clonidine; Cyprinidae; Electric Stimulation; Epinephrine; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Tetrodotoxin; Yohimbine | 1986 |
Neurochemical approaches to the prevention of ventricular fibrillation.
Topics: Animals; Atropine; Brain Chemistry; Cardiac Glycosides; Clonidine; Disease Susceptibility; Dogs; Humans; Morphine; Myocardial Contraction; Neurotransmitter Agents; Serotonin; Stress, Psychological; Vagotomy; Ventricular Fibrillation | 1986 |
Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Brain; Cardiovascular System; Clonidine; Dioxanes; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Phenylephrine; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Solanaceous Alkaloids; Vasodilator Agents | 1986 |
Neurotransmitters in "the smoke reflex" in rabbits.
Topics: Amitriptyline; Animals; Atropine; Clonidine; Heart Rate; Neurotransmitter Agents; Nicotiana; Norepinephrine; Plants, Toxic; Rabbits; Reflex; Smoke; Yohimbine | 1987 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Gastric lesion-preventing or -potentiating activity of clonidine in rats.
Topics: Animals; Anti-Ulcer Agents; Atropine; Clonidine; Dimaprit; Female; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stomach Ulcer; Thiourea | 1986 |
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy | 1987 |
In vivo demonstration of alpha-2-adrenoceptor-mediated inhibition of the excitatory non-cholinergic neurotransmission in guinea pig airways.
Topics: Acetylcholine; Airway Resistance; Animals; Atropine; Clonidine; Guinea Pigs; Hexamethonium Compounds; Male; Pressure; Receptors, Adrenergic, alpha; Respiration; Synaptic Transmission; Trachea; Vagus Nerve | 1985 |
Some pharmacological effects of tizanidine on smooth muscle organs and alpha 2-adrenoceptor.
Topics: Animals; Atropine; Binding, Competitive; Clonidine; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle Relaxants, Central; Muscle, Smooth; Pupil; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1985 |
Alpha 2-adrenoceptor-mediated contractile response to catecholamines in smooth muscle strips isolated from rainbow trout stomach (Salmo gairdneri).
Topics: Animals; Atropine; Catecholamines; Clonidine; Electric Stimulation; Epinephrine; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Stomach; Tetrodotoxin; Trout | 1986 |
In vitro effects of a mixture of Escherichia coli heat-stable enterotoxins on chloride flux in everted jejunal sacs of male pigs.
Topics: Animals; Atropine; Bacterial Toxins; Chlorides; Clonidine; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Intestinal Absorption; Jejunum; Male; Morphine; Pilocarpine; Swine; Vasoactive Intestinal Peptide | 1988 |
Behavioral effects of toxic doses of soman, an organophosphate cholinesterase inhibitor, in the rat: protection afforded by clonidine.
Topics: Animals; Atropine; Behavior, Animal; Cholinergic Fibers; Clonidine; Lethal Dose 50; Male; Rats; Soman | 1988 |
Opioid modulation of baroreceptor reflex sensitivity in dogs.
Topics: Animals; Atropine; Clonidine; Dogs; Endorphins; Hemodynamics; Male; Morphine; Naloxone; Phenylephrine; Pressoreceptors; Reflex; Vagus Nerve | 1987 |
Pharmacological characterization of alcohol and barbital physical dependence in mice.
Topics: Animals; Atropine; Barbital; Barbiturates; Clonidine; Ethanol; Male; Mice; Muscimol; Propranolol; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Blocking effects of alinidine on negative chronotropic and inotropic responses to vagal stimulation and injected acetylcholine and carbachol in dogs.
Topics: Acetylcholine; Adenosine; Animals; Atropine; Carbachol; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Heart Rate; Myocardial Contraction; Vagus Nerve | 1987 |
The effects of phorbol esters on fluid transport and blood flow in the small intestine.
Topics: Animals; Atropine; Blood Pressure; Cats; Clonidine; Female; Intestinal Secretions; Intestine, Small; Male; Phorbol Esters; Rats; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance | 1986 |
Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypertension; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Propranolol; Rats; Tachycardia; Yohimbine | 1986 |
Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level.
Topics: Animals; Apomorphine; Atropine; Bicuculline; Clonidine; Corticosterone; Dexamethasone; Diazepam; Drug Interactions; Female; Haloperidol; Picrotoxin; Rats; Rats, Inbred Strains; Yohimbine | 1986 |
Clonidine protection from the toxicity of soman, an organophosphate acetylcholinesterase inhibitor, in the mouse.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Clonidine; Drug Interactions; Kinetics; Male; Mice; Receptors, Muscarinic; Soman | 1986 |
Selective antagonism by clonidine of the stereotyped and non-stereotyped motor activity elicited by atropine.
Topics: Animals; Atropine; Clonidine; Male; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1986 |
Effects of centrally administered naloxone on gastrointestinal myoelectrical activity in morphine-dependent rats.
Topics: Animals; Atropine; Clonidine; Digestive System; Electrophysiology; Enkephalin, Leucine; Gastrointestinal Motility; Indomethacin; Injections, Intraventricular; Injections, Subcutaneous; Male; Methysergide; Morphine; Naloxone; Phentolamine; Rats; Substance-Related Disorders; Tolazoline | 1987 |
Effects of Escherichia coli heat-stable enterotoxin, atropine, clonidine, and morphine on chloride efflux from isolated enterocytes.
Topics: Animals; Atropine; Chlorides; Clonidine; Enterotoxins; Escherichia coli; Intestinal Absorption; Intestine, Small; Male; Morphine; Swine | 1985 |
Reduction of centrally-stimulated gastric acid secretion by tizanidine, a new imidazoline derivative, in anesthetized rats.
Topics: Anesthesia; Animals; Atropine; Bethanechol Compounds; Clonidine; Deoxyglucose; Electric Stimulation; Gastric Acid; Male; Muscle Relaxants, Central; Phentolamine; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1985 |
Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction.
Topics: Acetylcholine; Animals; Atrioventricular Node; Atropine; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; Male; Norepinephrine; Parasympathetic Nervous System; Parasympatholytics; Premedication; Propranolol; Sinoatrial Node; Stellate Ganglion; Time Factors; Vagus Nerve | 1985 |
The use of two different pharmacological principles to inhibit a cholinergic bronchospasm in guinea pig.
Topics: Aerosols; Animals; Atropine; Bronchial Spasm; Clonidine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male | 1985 |
Centrally mediated cardiovascular effects of nicergoline in the dog compared to those of clonidine.
Topics: Animals; Atropine; Blood Pressure; Clonidine; Dogs; Ergolines; Female; Guanethidine; Heart Rate; Hemodynamics; Male; Nicergoline; Parasympathetic Nervous System; Phenylephrine; Pressoreceptors; Reflex; Time Factors | 1985 |
Modulating effect of central adrenergic neurones on a vagally mediated cardioinhibitory reflex.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Chlorpromazine; Clonidine; Depression, Chemical; Dogs; Female; Heart; Heart Rate; Isoproterenol; Male; Methacholine Compounds; Neurons; Phentolamine; Receptors, Cholinergic; Reflex; Sympathetic Nervous System; Vagus Nerve | 1973 |
Effects of clonidine and some alpha-adrenoreceptor blocking agents on avoidance conditioned reflexes in rats: their interactions and antagonism by atropine.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Avoidance Learning; Clonidine; Conditioning, Classical; Depression, Chemical; Dibenzylchlorethamine; Male; Phenoxybenzamine; Phentolamine; Rats; Time Factors; Tolazoline; Yohimbine | 1974 |
Central hypothermia by 2-deoxy-D-glucose: antagonism by alpha-adrenergic activation.
Topics: Adrenal Glands; Adrenergic alpha-Agonists; Animals; Atropine; Body Temperature; Brain Chemistry; Clonidine; Depression, Chemical; Dextroamphetamine; Dopamine; Female; Fluorometry; Glucose; Hypothalamus; Imidazoles; Methyltyrosines; Norepinephrine; Phentolamine; Pimozide; Piperazines; Rats; Serotonin; Time Factors; Tryptamines | 1974 |
Influence of autonomic blockade on the reduction in myocardial performance produced by clonidine.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Atropine; Autonomic Nervous System; Benzopyrans; Blood Pressure; Cardiac Catheterization; Cardiac Output; Carotid Sinus; Clonidine; Depression, Chemical; Dogs; Female; Heart; Heart Rate; Heart Ventricles; Male; Parasympathomimetics; Propanolamines; Reserpine; Stimulation, Chemical; Sulfides; Time Factors; Vagotomy; Vagus Nerve; Vascular Resistance | 1974 |
[Lifting with clonidine of atropinic inhibition of heart-moderation tonus].
Topics: Animals; Antihypertensive Agents; Atropine; Bradycardia; Clonidine; Dogs; Drug Antagonism; Electrocardiography; Female; Heart; Heart Rate; Imidazoles; Male | 1971 |
An investigation on the behavioral and hypothermic effects of yohimbine: interaction with drugs affecting central and peripheral monoamines.
Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Benserazide; Biogenic Amines; Body Temperature; Catecholamines; Chlorisondamine; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Haloperidol; Humans; Lysergic Acid Diethylamide; Male; Methysergide; Motor Activity; Pargyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Stereotyped Behavior; Yohimbine | 1974 |
Evidence for a central activation of a vagal cardiodepressor reflex by clonidine.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Atropine; Blood Pressure; Bradycardia; Central Nervous System; Clonidine; Electrocardiography; Gallamine Triethiodide; Guanethidine; Heart Rate; Naphazoline; Neuromuscular Depolarizing Agents; Norepinephrine; Vagus Nerve | 1972 |
Modification of the caffeine-induced locomotor stimulation by a cholinergic mechanism.
Topics: Animals; Antiparkinson Agents; Atropine; Benztropine; Caffeine; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Female; Locomotion; Mice; Mice, Inbred Strains; Physostigmine; Piperazines; Pyrimidines; Reserpine; Stimulation, Chemical; Time Factors | 1974 |
Effect of clonidine on heart rate in dogs with acute or chronic heart block.
Topics: Anesthesia; Animals; Atropine; Chloralose; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Block; Heart Rate; Male; Vagotomy; Vagus Nerve | 1974 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
The effect of clonidine on adrenergic nerve function in vagotomized and nonvagotomized animals.
Topics: Animals; Atropine; Blood Pressure; Carbamates; Chlorisondamine; Clonidine; Dogs; Electric Stimulation; Female; Heart Rate; Male; Norepinephrine; Piperazines; Pressoreceptors; Quaternary Ammonium Compounds; Tyramine; Vagus Nerve | 1973 |
Susceptibility of hypertensive rats to a new hypotensive agent, ST-155 (catapres): 2-(2,6-dichorophenylamino)-2-imidazoline hydrochloride.
Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Clonidine; Heart Rate; Hexamethonium Compounds; Imidazoles; Isoproterenol; Male; Papaverine; Plants, Medicinal; Plants, Toxic; Rats; Rats, Inbred Strains; Vagus Nerve; Veratrum | 1971 |
Colonic secretion mediated by prostaglandin E2 and 5-hydroxytryptamine may contribute to diarrhea due to morphine withdrawal in the rat.
Topics: Animals; Atropine; Clonidine; Colon; Cyclic AMP; Diarrhea; Dinoprostone; Female; Humans; Indomethacin; Ketanserin; Morphine Dependence; Naloxone; Piperidines; Prostaglandins E; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome | 1984 |
Clonidine delays small intestinal transit in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Gastric Emptying; Gastrointestinal Motility; Intestine, Small; Male; Rats; Time Factors | 1980 |
Selective effects of clonidine on the canine sinus node.
Topics: Animals; Atropine; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Heart Rate; Injections, Intravenous; Male; Neurotransmitter Agents; Norepinephrine; Receptors, Adrenergic, alpha; Sinoatrial Node; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 1980 |
Drug-induced changes of epinephrine turnover in the rat hypothalamus.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Atropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Epinephrine; Hydroxydopamines; Hypothalamus; Male; Oxotremorine; Psychotropic Drugs; Rats | 1981 |
alpha-Adrenoceptive influences on hippocampal theta rhythm in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Behavior, Animal; Clonidine; Electroencephalography; Hippocampus; Immobilization; Rats; Rats, Inbred Strains; Theta Rhythm | 1981 |
Presynaptic effect of clonidine antagonized by the tetramine disulphide, benextramine.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Cocaine; Cystamine; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Neurons; Phentolamine; Synapses | 1982 |
Management of clonidine ingestion in children.
Topics: Atropine; Blood Pressure; Charcoal; Child, Preschool; Clonidine; Coma; Dopamine; Emergencies; Female; Heart Rate; Humans; Infant; Ipecac; Male; Norepinephrine; Respiration; Sulfites; Tolazoline | 1983 |
A physiological and pharmacological analysis of the electrodermal response in the rat.
Topics: Animals; Antihypertensive Agents; Atropine; Brain; Clonidine; Electric Stimulation; Evoked Potentials; Female; Galvanic Skin Response; Hexamethonium; Hexamethonium Compounds; Male; Rats; Stereotaxic Techniques; Sympathetic Nervous System; Yohimbine | 1984 |
[Relationship between the hypotensive effect of clonidine and the central cholinergic nervous system].
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Guinea Pigs; Male; Parasympathetic Nervous System; Physostigmine; Receptors, Adrenergic, alpha | 1982 |
Antihypertensive effect of the GABA receptor agonist muscimol in spontaneously hypertensive rats. Role of the sympathoadrenal axis.
Topics: Adrenal Glands; Animals; Atropine; Blood Pressure; Catecholamines; Clonidine; Efferent Pathways; Heart Rate; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Splanchnic Nerves; Sympathectomy, Chemical; Sympathetic Nervous System; Vagotomy | 1984 |
Clonidine-induced hypothermia: possible involvement of cholinergic and serotonergic mechanisms.
Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Animals; Atropine; Body Temperature; Clonidine; Cyproheptadine; Hypothalamus; Male; Microinjections; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1984 |
The effects of clonidine on electrically-induced contractions of rat detrusor strips in vitro.
Topics: Acetylcholine; Animals; Atropine; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Sympatholytics; Theophylline; Urinary Bladder | 1983 |
Cholinergic mediation of growth hormone secretion elicited by arginine, clonidine, and physical exercise in man.
Topics: Acetylcholine; Adolescent; Adult; Arginine; Atropine; Clonidine; Female; Growth Hormone; Humans; Male; Physical Exertion; Prolactin | 1984 |
Effects of fentanyl, naloxone, and clonidine on hemodynamics and plasma catecholamine levels in dogs.
Topics: Anesthesia, General; Animals; Atropine; Catecholamines; Clonidine; Dogs; Drug Interactions; Fentanyl; Hemodynamics; Naloxone; Tolazoline | 1983 |
Bronchopulmonary effects of clonidine on the bronchomotor responses of the guinea-pig.
Topics: Acetylcholine; Airway Resistance; Animals; Atropine; Bronchi; Clonidine; Drug Interactions; Guinea Pigs; Hemodynamics; In Vitro Techniques; Lung; Male; Muscle, Smooth; Pentobarbital; Propranolol; Reserpine; Respiration | 1983 |
Monoamine replacement after reserpine: catecholaminergic agonists restore motor activity but phenylethylamine restores atropine-resistant neocortical low voltage fast activity.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Atropine; Cerebral Cortex; Clonidine; Dextroamphetamine; Evoked Potentials; Levodopa; Lysergic Acid Diethylamide; Motor Activity; Phenethylamines; Rats; Receptors, Cholinergic; Reserpine | 1980 |
Effects of prazosin and piperoxan on central cardiovascular actions of St 91 in cats.
Topics: Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Piperidines; Piperoxan; Prazosin; Quinazolines; Vertebral Artery | 1982 |
Pacemaker selectivity: influence on rabbit atria of ionic environment and of alinidine, a possible anion antagonist.
Topics: Animals; Atrial Function; Atropine; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Female; Heart Atria; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Rabbits; Sinoatrial Node | 1981 |
Modulation of reflex sympathetic discharge by the cholinergic agonist oxotremorine and by clonidine.
Topics: Animals; Atropine; Cardiovascular System; Carotid Sinus; Cats; Clonidine; Electric Stimulation; Evoked Potentials; Female; Hemodynamics; Male; Neural Pathways; Norepinephrine; Oxotremorine; Reflex; Sympathetic Nervous System | 1981 |
A comparison of muscarinic cholinergic involvement in the antinociceptive effects of morphine and clonidine in the mouse.
Topics: Animals; Atropine; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Morphine; Naloxone; Nociceptors; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Evidence for selective inhibition of sympathetic outflow by oxotremorine.
Topics: Animals; Atropine; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Male; Oxotremorine; Sympathetic Nervous System | 1980 |
Differential regulation of muscarinic agonist binding sites following chronic cholinesterase inhibition.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Clonidine; Male; Paraoxon; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle inflorescence extracts.
Topics: Animals; Areca; Atropine; Blood Pressure; Capsaicin; Chromatography, High Pressure Liquid; Clonidine; Eugenol; Heart Rate; Injections, Intra-Arterial; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Male; Plant Extracts; Plants, Medicinal; Propranolol; Rats; Rats, Wistar; Safrole; Substance P; Vagotomy | 1995 |
Release of endogenous acetylcholine from a vascularly perfused rat stomach in vitro; inhibition by M3 muscarinic autoreceptors and alpha-2 adrenoceptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium; Clonidine; Diamines; Drug Interactions; Electric Stimulation; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Perfusion; Phenylephrine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Tetrodotoxin; Vagus Nerve | 1993 |
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Differential effects of clonidine on renal sympathetic nerve activity and heart rate at onset of static exercise.
Topics: Adrenergic Fibers; Animals; Atropine; Blood Pressure; Cats; Clonidine; Consciousness; Heart Rate; Injections, Intravenous; Kidney; Physical Conditioning, Animal; Time Factors | 1995 |
Effects of atropine, pirenzepine, clonidine, and morphine on biphasic response of rat gastric fundus to field stimulation.
Topics: Animals; Atropine; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Morphine; Muscle Contraction; Pirenzepine; Rats; Rats, Sprague-Dawley | 1994 |
Acetylcholine release from airway cholinergic nerves in horses with heaves, an airway obstructive disease.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Cholinergic Fibers; Chromatography, High Pressure Liquid; Clonidine; Dinoprostone; Electric Stimulation; Female; Horse Diseases; Horses; Indomethacin; Lung Diseases, Obstructive; Male; Muscle, Smooth; Parasympathetic Nervous System; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Stimulation, Chemical; Trachea | 1995 |
Colonic giant migrating contractions induced by glycerol enema in anesthetized rats.
Topics: Animals; Atropine; Catheterization; Clonidine; Colon; Enema; Ganglionic Blockers; Gastrointestinal Motility; Glycerol; Hexamethonium; Hexamethonium Compounds; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar | 1993 |
Release of acetylcholine and noradrenaline from the cholinergic and adrenergic afferents in rat hippocampal CA1, CA3 and dentate gyrus regions.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Atropine; Berberine; Choline; Clonidine; Hippocampus; In Vitro Techniques; Luminescent Measurements; Male; Norepinephrine; Oxotremorine; Physostigmine; Pyramidal Tracts; Rats; Rats, Wistar; Tritium | 1994 |
Acid secretory and duodenal ulcerogenic responses induced by mepirizole in anesthetized rats. Relation to body temperature.
Topics: Animals; Atropine; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Epirizole; Ganglionic Blockers; Gastric Acid; Hexamethonium; Hexamethonium Compounds; Male; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Vagotomy | 1994 |
Effect of 'autonomic blockade' on cardiac beta-adrenergic chronotropic responsiveness in healthy young, healthy elderly and endurance-trained elderly subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Atropine; Autonomic Nervous System; Blood Pressure; Clonidine; Heart; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Physical Endurance; Stimulation, Chemical | 1994 |
Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems.
Topics: Animals; Atropine; Behavior, Animal; Carbachol; Clonidine; Dose-Response Relationship, Drug; Edrophonium; Hot Temperature; Injections, Spinal; Male; Mecamylamine; Morphine; Neostigmine; Neuromuscular Blocking Agents; Pain Threshold; Premedication; Rats; Rats, Sprague-Dawley; Reaction Time | 1994 |
Inhibition by alpha 2-adrenoceptor agonists of contractions of rabbit isolated colon elicited by pelvic nerve stimulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Colon; Drug Resistance; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pelvis; Quinoxalines; Rabbits | 1993 |
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Meperidine; Methoxydimethyltryptamines; Neurotransmitter Agents; Yohimbine | 1993 |
Alpha 1-adrenoceptors in the human prostatic urethra are different from those of the human peripheral arteries.
Topics: Arteries; Atropine; Clonidine; Dioxanes; Humans; Iliac Artery; Isometric Contraction; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Urethra; Yohimbine | 1993 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin | 1993 |
Influence of endogenous cholinergic tone and alpha-adrenergic pathways on growth hormone responses to His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 in the dog.
Topics: Animals; Atropine; Cholinergic Fibers; Clonidine; Dogs; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Hormones; Male; Methoxamine; Oligopeptides; Prazosin; Pyridostigmine Bromide; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1993 |
Neuroendocrine control of immunoreactive growth hormone and bioactive prolactin secretion in neonatal rats: ontogeny and interactions between the serotonergic, cholinergic and alpha 2-adrenergic systems.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Atropine; Choline; Clonidine; Cyproheptadine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin | 1993 |
Mechanisms involved in electrically-induced responses of rat seminal vesicles.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Clonidine; Electric Stimulation; Guanethidine; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Wistar; Seminal Vesicles; Vasoconstrictor Agents | 1995 |
Is alpha-adrenoceptor blockade responsible for atropine flush?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Male; Phentolamine; Phenylephrine; Prazosin; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Skin; Thromboxane A2; Vasodilation | 1995 |
Interactions of the cardiac chronotropic effects of rilmenidine with the autonomic nervous system in conscious dogs: comparison with clonidine.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Chronic Disease; Clonidine; Depression, Chemical; Dogs; Female; Heart Block; Heart Rate; Male; Muscarinic Antagonists; Oxazoles; Phenoxybenzamine; Pindolol; Rilmenidine; Yohimbine | 1996 |
A simple method for measuring the effects of drugs on intestinal longitudinal and circular muscle.
Topics: Animals; Atropine; Brimonidine Tartrate; Clonidine; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1996 |
Study of human serum albumin structure by dynamic light scattering: two types of reactions under different pH and interaction with physiologically active compounds.
Topics: Atropine; Carbachol; Chlorpromazine; Clonidine; Diphenhydramine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phenylephrine; Propranolol; Protein Binding; Scattering, Radiation; Serum Albumin; Yohimbine | 1998 |
Inhibition of stress-stimulated colonic propulsion by alpha 2-adrenoceptor antagonists in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Colon; Defecation; Gastrointestinal Motility; Gastrointestinal Transit; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stress, Physiological; Yohimbine | 1998 |
Neuropeptide Y is a prejunctional inhibitor of vagal but not sympathetic inotropic responses in guinea-pig isolated left atria.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Atropine; Cardiotonic Agents; Clonidine; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscarinic Antagonists; Myocardial Contraction; Neuropeptide Y; Propranolol; Refractory Period, Electrophysiological; Sympathetic Nervous System; Synaptic Transmission; Vagus Nerve | 1999 |
Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anxiety; Atropine; Clonidine; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Yohimbine | 2000 |
Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.
Topics: Adrenergic alpha-Agonists; Animals; Antioxidants; Atropine; Carcinogens; Cimetidine; Clonidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hypoglycemic Agents; Male; Microsomes, Liver; Muscarinic Antagonists; Nitrosamines; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tolbutamide; Vitamins | 2001 |
Potential therapeutic agents in the management of organophosphorus poisoning.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Humans; Insecticides; Magnesium; Mice; Muscarinic Antagonists; Organophosphorus Compounds; Poisoning; Pralidoxime Compounds; Sodium Fluoride | 2002 |
Effects of cholinergic and noradrenergic agents on locomotion in the mudpuppy (Necturus maculatus).
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Atropine; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Clonidine; Excitatory Amino Acid Agonists; Interneurons; Locomotion; Motor Neurons; Muscarinic Antagonists; N-Methylaspartate; Necturus maculosus; Nerve Net; Norepinephrine; Physostigmine; Spinal Cord | 2002 |
Acute effects of aflatoxins on guinea pig isolated ileum.
Topics: Aflatoxins; Animals; Apamin; Atropine; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Tetrodotoxin | 2002 |
Plasticity in action of intrathecal clonidine to mechanical but not thermal nociception after peripheral nerve injury.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Analgesics; Animals; Atropine; Aziridines; Behavior, Animal; Choline; Clonidine; Hot Temperature; Injections, Spinal; Ligation; Male; Muscarinic Antagonists; Neuromuscular Blocking Agents; Neurotoxins; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Pressure; Rats; Rats, Sprague-Dawley | 2003 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analgesics; Animals; Atropine; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Diamines; Injections, Spinal; Male; Mice; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Pain; Pain Threshold; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord; Streptozocin; Stress, Mechanical; Time Factors | 2004 |
An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice.
Topics: Animals; Atropine; Calcium Channels; Clonidine; Gastrointestinal Transit; Glyburide; Insulin; Insulin Secretion; Intestine, Small; Male; Mice; Naloxone; Ondansetron; Receptors, Opioid; Verapamil | 2006 |
Wistar Kyoto rats have impaired gastric accommodation compared to Sprague Dawley rats due to increased gastric vagal cholinergic tone.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Clonidine; Enzyme Inhibitors; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Vagus Nerve; Vasodilator Agents | 2006 |
Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models.
Topics: Animals; Atropine; Clonidine; Constipation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Indoles; Loperamide; Male; Mice; Mice, Inbred Strains; Mustard Plant; Naloxone; Plant Oils; Transient Receptor Potential Channels; TRPA1 Cation Channel; Yohimbine | 2009 |
Scale exponents of blood pressure and heart rate during autonomic blockade as assessed by detrended fluctuation analysis.
Topics: Adult; Atropine; Autonomic Nervous System; Blood Pressure; Clonidine; Electrocardiography; Fractals; Heart; Heart Rate; Humans; Male; Middle Aged; Parasympatholytics; Propranolol; Supine Position; Sympatholytics | 2011 |
Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury.
Topics: Acetylcholine; Adjuvants, Anesthesia; Analgesics; Animals; Anterior Horn Cells; Atropine; Brain-Derived Neurotrophic Factor; Calcium-Binding Proteins; Choline O-Acetyltransferase; Clonidine; Disease Models, Animal; Dopamine beta-Hydroxylase; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Immunotoxins; Male; Microfilament Proteins; Norepinephrine; Pain Measurement; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Spinal Nerves; Synaptosomes; Time Factors; Tritium | 2012 |
Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice.
Topics: Acetylcholinesterase; Alkaloids; Ambenonium Chloride; Analgesics; Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Chronic Pain; Clonidine; Gyrus Cinguli; Hyperalgesia; Inflammation; Learning; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neuralgia; Pain Threshold; Peroneal Nerve; Receptors, Muscarinic; Sesquiterpenes | 2015 |
Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus.
Topics: Amines; Analgesics; Animals; Antihypertensive Agents; Atropine; Bronchodilator Agents; Clonidine; CREB-Binding Protein; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gabapentin; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Norepinephrine; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Spinal Cord Dorsal Horn; Time Factors | 2016 |
Adult clonidine overdose: prolonged bradycardia and central nervous system depression, but not severe toxicity.
Topics: Adolescent; Adult; Aged; Antidotes; Antihypertensive Agents; Atropine; Bradycardia; Central Nervous System Diseases; Clonidine; Drug Overdose; Female; Glasgow Coma Scale; Humans; Length of Stay; Male; Middle Aged; Naloxone; Retrospective Studies; Young Adult | 2017 |
Validity and variability of xBRS: instantaneous cardiac baroreflex sensitivity.
Topics: Adult; Antihypertensive Agents; Atropine; Autonomic Nervous System; Baroreflex; Blood Pressure; Blood Pressure Determination; Clonidine; Heart; Humans; Male; Nitroprusside; Phenylephrine; Propranolol; Vasoconstrictor Agents | 2017 |
Myopia-Inhibiting Concentrations of Muscarinic Receptor Antagonists Block Activation of Alpha2A-Adrenoceptors In Vitro.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Atropine; Carbachol; Chickens; Cholinergic Agonists; Clonidine; CRISPR-Associated Protein 9; Gene Knockdown Techniques; HEK293 Cells; Humans; Ligands; Muscarinic Antagonists; Myopia; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Transfection | 2018 |
Reality of clonidine poisoning in children and adolescents.
Topics: Adolescent; Atropine; Bradycardia; Child; Child, Preschool; Clonidine; Female; Humans; Hypotension; Male; Naloxone; Poisoning; Retrospective Studies | 2023 |