clonidine has been researched along with atipamezole in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agbaba, D; Azzali, E; Costantino, G; Glisic, S; Laurila, JM; Nikolic, K; Perovic, V; Pieroni, M; Radi, M; Scheinin, M; Srdic-Rajic, T; Tassini, S; Veljkovic, N; Vucicevic, J | 1 |
| Dickenson, AH; Kalso, EA; McQuay, HJ; Sullivan, AF | 1 |
| Puke, MJC; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Jäkälä, P; Lammintausta, R; Riekkinen, P; Sirviö, J | 1 |
| Durcan, MJ; Linnoila, M; Lister, RG | 1 |
| MacDonald, E; Scheinin, H; Scheinin, M | 1 |
| Dement, WC; Edgar, DM; Maze, M; Seidel, WF | 1 |
| Dalley, JW; Stanford, SC | 1 |
| Duggan, S; Hong, M; Jhamandas, K; Milne, B | 1 |
| Ferrè, JP; Intorre, L; Maugeri, S; Soldani, G | 1 |
| Hämäläinen, MM; Pertovaara, A | 1 |
| Dowlatshahi, P; Yaksh, TL | 1 |
| Colpaert, F; Marien, M; Tellez, S | 1 |
| Grubb, MC; Guyenet, PG; Stornetta, RL | 1 |
| Czuczwar, SJ; Dzieciuch, JA; Kleinrok, Z; Przesmycki, K | 1 |
| Baertschi, AJ; Grubb, MC; Guyenet, PG; Pence, R; Stornetta, RL | 1 |
| Audinot, V; Boutin, JA; Cordi, A; Cussac, D; Dekeyne, A; Duqueyroix, D; Girardon, S; Lacoste, JM; Millan, MJ; Milligan, G; Mullot, J; Newman-Tancredi, A; Nicolas, JP; Renouard-Try, A | 1 |
| Auclair, A; Bosc, C; Brocco, M; Cordi, A; Dekeyne, A; Gobert, A; Lacoste, JM; Lejeune, F; Millan, MJ; Rivet, JM | 1 |
| Avedian, T; Jentsch, JD; Kuperman, J; Marrs, W; Roth, RH | 1 |
| Bakshi, VP; Carasso, BS; Geyer, MA; Palomo, J; Powell, SB | 1 |
| Lapiz, MD; Morilak, DA | 1 |
| Cahill, CM; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Cahill, CM; Grenier, P; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Bhide, N; Bishop, C; Conti, M; George, JA; Hallmark, J; Ostock, CY; Palumbo, N | 1 |
| Dickenson, AH; Patel, R; Porreca, F; Qu, C; Xie, JY | 1 |
| Bakshi, VP; Barth, KJ; Ciucci, MR; Grant, LM; Kelm-Nelson, CA; Muslu, C | 1 |
27 other study(ies) available for clonidine and atipamezole
| Article | Year |
|---|---|
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.
Topics: Adrenergic alpha-Agonists; Antibiotics, Antineoplastic; Apoptosis; Doxorubicin; Drug Synergism; Humans; K562 Cells; Ligands; Molecular Structure; Oxazoles; Receptors, Adrenergic, alpha-2; Rilmenidine | 2016 |
The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Analgesics; Anesthesia; Animals; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Imidazoles; Male; Medetomidine; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord | 1992 |
The depressive effect of intrathecal clonidine on the spinal flexor reflex is enhanced after sciatic nerve section in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Axons; Blood Pressure; Clonidine; Decerebrate State; Female; Heart Rate; Imidazoles; Injections, Spinal; Norepinephrine; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Reflex; Sciatic Nerve; Spinal Cord | 1992 |
Effect of alpha2 antagonists and an agonist on EEG slowing induced by scopolamine and lesion of the nucleus basalis.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Clonidine; Electroencephalography; Imidazoles; Norepinephrine; Occipital Lobe; Olivary Nucleus; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Yohimbine | 1990 |
Interactions of alpha 2-adrenoceptor antagonists with medetomidine and with ethanol in a holeboard test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dioxanes; Ethanol; Idazoxan; Imidazoles; Male; Medetomidine; Mice | 1989 |
Comparison of free MHPG in rat cerebrospinal fluid with free and conjugated MHPG in brain tissue: effects of drugs modifying noradrenergic transmission.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Brain Chemistry; Clonidine; Glycols; Imidazoles; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Reserpine; Synaptic Transmission | 1986 |
Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Circadian Rhythm; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Motor Activity; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sleep; Sleep, REM | 1995 |
Contrasting effects of the imidazol(in)e alpha 2-adrenoceptor agonists, medetomidine, clonidine and UK 14,304 on extraneuronal levels of noradrenaline in the rat frontal cortex: evaluation using in vivo microdialysis and synaptosomal uptake studies.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Frontal Lobe; Imidazoles; Male; Medetomidine; Microdialysis; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptosomes; Time Factors | 1995 |
The role of excitatory amino acids in the expression of precipitated acute and chronic clonidine withdrawal: an in vivo voltammetric study in the rat locus coeruleus.
Topics: Acute Disease; Animals; Catechols; Chronic Disease; Clonidine; Electrophysiology; Excitatory Amino Acids; Imidazoles; Locus Coeruleus; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Effects of medetomidine on intestinal and colonic motility in the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Colon; Dogs; Drug Interactions; Electrophysiology; Gastrointestinal Motility; Hypnotics and Sedatives; Imidazoles; Injections, Intravenous; Jejunum; Medetomidine; Yohimbine | 1994 |
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Topics: Analysis of Variance; Animals; Cerebellum; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Imidazoles; Lidocaine; Male; Medetomidine; Medulla Oblongata; Microinjections; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Skin Temperature; Spinal Cord; Time Factors | 1993 |
Differential effects of two intraventricularly injected alpha 2 agonists, ST-91 and dexmedetomidine, on electroencephalogram, feeding, and electromyogram.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Conscious Sedation; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Feeding Behavior; Imidazoles; Injections, Intraventricular; Male; Medetomidine; Methoxamine; Prazosin; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
Acetylcholine release in the rat prefrontal cortex in vivo: modulation by alpha 2-adrenoceptor agonists and antagonists.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Guanabenz; Idazoxan; Imidazoles; Male; Microdialysis; Piperoxan; Prefrontal Cortex; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley | 1997 |
Atipamezole-precipitated clonidine withdrawal induces c-Fos expression in rat central nervous system.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Central Nervous System; Clonidine; Drug Implants; Imidazoles; Immunohistochemistry; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 1997 |
An isobolographic analysis of drug interaction between intrathecal clonidine and baclofen in the formalin test in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Baclofen; Clonidine; Drug Interactions; Formaldehyde; GABA Agonists; Imidazoles; Injections, Spinal; Male; Motor Activity; Pain Threshold; Rats; Rats, Wistar | 1998 |
Antagonist precipitated clonidine withdrawal in rat: effects on locus coeruleus neurons, sympathetic nerves and cardiovascular parameters.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular System; Clonidine; Consciousness; Halothane; Heart Rate; Idazoxan; Imidazoles; Locus Coeruleus; Male; Neurons; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Substance Withdrawal Syndrome; Sympathetic Nervous System; Sympatholytics; Vascular Resistance | 1998 |
S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Body Temperature; CHO Cells; Clonidine; Cricetinae; Dexmedetomidine; Humans; Imidazoles; Imidazoline Receptors; Male; Mice; Oxazoles; Rats; Rats, Wistar; Receptors, Drug | 2000 |
S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Biogenic Monoamines; Clonidine; Dexmedetomidine; Imidazoles; Locus Coeruleus; Male; Mice; Motor Activity; Oxazoles; Raphe Nuclei; Rats; Rats, Wistar; Ventral Tegmental Area; Vocalization, Animal | 2000 |
Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Benzylamines; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanfacine; Imidazoles; Male; Memory Disorders; Memory, Short-Term; Neurotransmitter Uptake Inhibitors; Phencyclidine; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Sex Factors; Spatial Behavior | 2005 |
Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Guanfacine; Imidazoles; Injections; Male; Medetomidine; Neural Inhibition; Piperazines; Prazosin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Reflex, Startle; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Yohimbine | 2005 |
Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Attention; Clonidine; Cognition; Data Interpretation, Statistical; Excitatory Postsynaptic Potentials; Imidazoles; Male; Memory, Short-Term; Microinjections; Norepinephrine; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Synaptic Transmission | 2006 |
Low dose alpha-2 antagonist paradoxically enhances rat norepinephrine and clonidine analgesia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesia; Analgesics; Animals; Clonidine; Drug Synergism; Imidazoles; Male; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley | 2011 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesia; Analgesics; Animals; Clonidine; Drug Tolerance; Imidazoles; Injections, Spinal; Male; Morphine; Norepinephrine; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic | 2014 |
Modulation of L-DOPA's antiparkinsonian and dyskinetic effects by α2-noradrenergic receptors within the locus coeruleus.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antiparkinson Agents; Clonidine; Dyskinesia, Drug-Induced; Imidazoles; Levodopa; Locus Coeruleus; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 2015 |
Selective deficiencies in descending inhibitory modulation in neuropathic rats: implications for enhancing noradrenergic tone.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Animals; Avoidance Learning; Clonidine; Conditioning, Operant; Evoked Potentials; Imidazoles; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley | 2018 |
Noradrenergic receptor modulation influences the acoustic parameters of pro-social rat ultrasonic vocalizations.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; Male; Models, Animal; Norepinephrine; Propranolol; Rats; Rats, Long-Evans; Receptors, Adrenergic; Ultrasonics; Vocalization, Animal | 2018 |