clonidine and alinidine

clonidine has been researched along with alinidine in 123 studies

Research

Studies (123)

Timeframe	Studies, this research(%)	All Research%
pre-1990	91 (73.98)	18.7374
1990's	26 (21.14)	18.2507
2000's	6 (4.88)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kobinger, W; Lillie, C; Pichler, L	1
Henquin, JC; Jonas, JC; Plant, TD	1
Brown, MD; Hudlicka, O	1
Adachi, H; Kodama, K; Ogawa, T; Ohhara, H	1
Moulart, D; Preiser, JC; Vincent, JL	1
Haas, F; Heimisch, W; Mendler, N; Schad, H	1
Chiba, S; Furukawa, Y; Nakane, T	1
Bahavar, H; Ditter, H; Müller, KD; Schlepper, M	1
Cinquegrana, G; Condorelli, M; Duilio, C; Ferro, G; Spadafora, M; Spinelli, L	1
Angus, JA; McPherson, GA	1
Gilbertsen, RB; Lesch, ME; Schrier, DJ; Wright, CD	1
Gombotz, H	1
Henze, E; Koenig, W; Stauch, M; Sund, M; Wanjura, D	1
Brunner, F; Kukovetz, WR	2
Caucheteux, D; Gurné, O; Hanet, C; Hue, L; Maldague, P; Pouleur, H; Rousseau, MF	1
Chi, LG; Driscoll, EM; Frye, JW; Lucchesi, BR; Lynch, JJ; Uprichard, AC	1
Deering, AH; Harron, DW; McMahon, M; Scott, M; Shanks, RG	1
Lang, U; Walland, A	1
Boucher, M; Chapuy, E; Duchêne-Marullaz, P; Lefebvre, MA; Mignot, A	1
Bassoul, B; D'Athis, F; de la Coussaye, JE; Eledjam, JJ; Fabregat, J; Sassine, A	1
Akahane, K; Chiba, S; Furukawa, Y; Ogiwara, Y	1
Lang, U; Streller, I; Walland, A	1
Harron, DW; Shanks, RG	1
Dennis, PD; Garnham, C; Vaughan Williams, EM	1
Simoons, ML	1
Kobinger, W; Lillie, C	4
Aknin, P; Auffray, JP; Blin, D; Eon, B; Ouerghemmi, D	1
Gombotz, H; Metzler, H; Rehak, P; Winkler, G	1
Kobinger, W; Lillie, C; Reichhalter, R	1
Akahane, K; Chiba, S; Furukawa, Y; Haniuda, M; Ogiwara, Y	1
Jähnchen, E; Kasper, W; Meinertz, T	1
Balakumaran, K; Bokslag, M; Fels, PW; Hugenholtz, PG; Jovanovic, A; Lubsen, J; van Es, GA	1
Bednarz, B; Budaj, A; Burduk, P; Ceremuzynski, L; Chamiec, T; Czarnecki, W; Dluzniewski, M; Jurgiel, R; Nartowicz, E; Perkowicz, J	1
Kreuzer, H; Wiegand, V	1
Skarvan, K	1
Vaughan Williams, EM	1
Bouman, LN; Duivenvoorden, JJ; Giles, WR; Jongsma, HJ; Opthof, T; van Ginneken, AC	1
Goethals, M; Van Bogaert, PP	1
Duncker, DJ; Heere, TJ; Saxena, PR; Verdouw, PD	1
Krumpl, G; Mayer, N; Raberger, G; Schneider, W	2
Shanks, RG	1
Arnold, AE; Meij, SH; Serruys, PW; Soward, AL; van Es, GA	1
Iversen, S; Kleinpeter, UM; Mayer, E; Oelert, H; Schmiedt, W; Tesch, A	1
Degoutrie, G; Kaltenbach, M; Landgraf, H; Schräder, R	1
Atfani, M; Carpy, A; Stähle, H	1
Snyders, DJ; Van Bogaert, PP	1
Chiba, S; Furukawa, Y; Ogiwara, Y; Takeda, M	1
Hashimoto, K; Satoh, H	1
Andersen, KS; Grong, K; Lekven, J; Stangeland, L; Vik-Mo, H	1
Dennis, PD; Williams, EM	1
Bouman, LN; Duivenvoorden, JJ; Jongsma, HJ; Opthof, T; Vanginneken, AC	1
Friedrich, T; Hoffmann, M; Huckauf, H; Kammradt, G; Lichey, J	1
Krumpl, G; Raberger, G; Schneider, W	1
Hageman, GR; James, TN; Neely, BH; Urthaler, F	1
Brezina, M; Harron, DW; Kobinger, W; Lillie, C	1
Jaski, BE; Serruys, PW	1
Haberl, R; Steinbeck, G	1
Harron, DW; Riddell, JG; Shanks, RG	1
Ebm, W; Zilcher, H	1
Millar, JS; Williams, EM	2
Nawrath, H	1
Pichler, L	1
Angus, JA; Heinzow, BG; Korner, PI; Lew, MJ	1
Opie, LH	1
Decobert, M; Depoortere, H; Honoré, L	1
Harron, DW; Leahey, WJ; McNeill, J; Nicholls, DP; O'Connor, PC; Shanks, RG	1
Kawada, M; Satoh, K; Taira, N	1
Arndts, D; Finch, M; Harron, DW; Shanks, RG	1
Bokisch, AJ; Walker, RJ	1
Bechtold, H; Förster, I; Jähnchen, E; Kasper, W; Meier, R; Meinertz, T; Pop, T; Wiegand, U	1
Millar, JS; Vaughan Williams, EM	1
Bouman, LN; Duivenvoorden, JJ; Opthof, T; Treijtel, BW	1
Hugenholtz, PG; Simoons, ML	1
De Geest, H; Kesteloot, H; Piessens, J; Schurmans, J	1
Simoons, ML; Tummers, J; van Domburg, R; van Meurs-van Woezik, H	1
Fitzal, S; Semsroth, M; Zimpfer, M	1
Placheta, P; Raberger, G; Reiterer, W; Stanek, B	1
Harron, DW; Nicholls, DP; Shanks, RG	1
Scholtysik, G	1
Khosropour, R; Lackner, F; Zimpfer, M	1
Auböck, J; Konzett, H; Olbrich, E	1
Arndts, D; Harron, DW; Shanks, RG	1
Fitzal, S; Zimpfer, M	1
Angus, JA; Heinzow, BG; Korner, PI	1
Brutsaert, DL; De Clerck, NM; Sys, SU	1
Heuberger, S; Tritthart, HA; Windisch, H	1
Jähnchen, E; Kasper, W; Meinertz, T; Wiegand, UW	1
Hamer, J; Weerasuriya, K	1
Just, H; Kersting, F; Löllgen, H; Wollschläger, H	1
Arndts, D; Stähle, H	1
Arndts, D; Förster, HJ; Leb, G	1
Balakumaran, K; Simoons, ML	1
Arndts, D; Justus, H; Rominger, KL; Warnkross, H	1
Arndts, D; Forster, HJ	1
Rutteman, AM; Saxena, PR; Schamhardt, HC; van der Hoek, TM; Verdouw, PD	1
Traunecker, W; Walland, A	1
Blakemore, C; Larkman, A; Nicoll, A	1
BoSmith, RE; Briggs, I; Heapy, CG	1
BoSmith, RE; Briggs, I; Sturgess, NC	1
Boucher, M; Chapuy, E; Chassaing, C	2
Mutschler, E; Walland, A; Weihs, H	1
Challinor-Rogers, JL; Hay, TK; McPherson, GA	1
Ballet, A; Ector, H; Heidbüchel, H; Tack, J; Van de Werf, F; Vanneste, L	1
Brzostek, T; Collen, D; Heidbüchel, H; Janssens, L; Lesaffre, E; Mortelmans, L; Scheys, I; Van de Werf, F; Wackers, FJ; Willems, GM	1
Aidonidis, I; Brachmann, J; Kübler, W; Rizos, I; Stavridis, I; Toutouzas, P; Zacharoulis, A	1
Lodge, NJ; Smith, MA	1
Challinor-Rogers, JL; Du, XJ; McPherson, GA; Rosenfeldt, FL	1
Hasselblatt, A; Kowalewski, R; Leupolt, L; Rustenbeck, I	1
Bjercke, RJ; Brock, TA; Brown, MD; Tomanek, RJ; Zheng, W	1
Bell, K; Favaloro, J; Iskander, MM; Khalil, V; McPherson, GA	1
Camm, AJ; Yusuf, S	1
Christensen, LP; Lei, L; Tomanek, RJ; Weiss, RM; Zheng, W; Zhou, R	1
Christensen, LP; Dedkov, EI; Tomanek, RJ; Weiss, RM	1
Baruscotti, M; Bucchi, A; Difrancesco, D	1
Büter, I; Gams, E; Hohlfeld, T; Schipke, JD; Schmitz-Spanke, S	1
Benjamin, E; Berger, SR; Iberti, TJ; Kaplan, JA; Paluch, TA; Plawker, M	1

Reviews

6 review(s) available for clonidine and alinidine

Article	Year
Pharmacology, clinical pharmacology and potential therapeutic uses of the specific bradycardiac agent alinidine. European heart journal, 1985, Volume: 6, Issue:9 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Clonidine; Coronary Disease; Drug Evaluation; Heart Rate; Hemodynamics; Humans; Kinetics; Myocardial Infarction; Neurocirculatory Asthenia; Neuroleptanalgesia; Tachycardia	1985
Specific bradycardic agents--a novel pharmacological class? European heart journal, 1987, Volume: 8 Suppl L Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Benzazepines; Calcium Channel Blockers; Clonidine; Heart; Heart Rate; Isoindoles; Myocardial Contraction; Myocardium; Oxygen Consumption; Perfusion; Phthalimides	1987
Drug effects on the EEG of various species of laboratory animals. Neuropsychobiology, 1983, Volume: 9, Issue:4 Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine	1983
Sinus tachyarrhythmias and the specific bradycardic agents: a marriage made in heaven? Journal of cardiovascular pharmacology and therapeutics, 2003, Volume: 8, Issue:2 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Benzazepines; Calcium Channel Blockers; Clonidine; Diagnosis, Differential; Humans; Isoindoles; Ivabradine; Phthalimides; Pyrimidines; Sinoatrial Node; Tachycardia, Sinus; Vasodilator Agents; Verapamil	2003
Physiology and pharmacology of the cardiac pacemaker ("funny") current. Pharmacology & therapeutics, 2005, Volume: 107, Issue:1 Topics: Amino Acid Sequence; Animals; Benzazepines; Cardiovascular Agents; Clonidine; Cyclic Nucleotide-Gated Cation Channels; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Nerve Tissue Proteins; Potassium Channels; Pyrimidines; Sinoatrial Node; Structure-Activity Relationship	2005
[Selective I(f) channel inhibition: an alternative for treating coronary artery disease?]. Herz, 2006, Volume: 31, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Cardiotonic Agents; Cardiovascular Agents; Clonidine; Coronary Artery Disease; Humans; Isoindoles; Ivabradine; Phthalimides; Practice Guidelines as Topic; Practice Patterns, Physicians'	2006

Trials

20 trial(s) available for clonidine and alinidine

Article	Year
Alinidine in chronic stable angina: the effect on diastolic perfusion time. Cardiology, 1990, Volume: 77, Issue:4 Topics: Angina Pectoris; Cardiovascular Agents; Chronic Disease; Clonidine; Diastole; Double-Blind Method; Exercise Test; Humans; Male	1990
Effect of the combination of alinidine and other anti-anginal drugs on heart rate and blood pressure in healthy volunteers. British journal of clinical pharmacology, 1989, Volume: 27, Issue:1 Topics: Adult; Angina Pectoris; Atenolol; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Drug Interactions; Heart Rate; Humans; Male; Nifedipine; Nitroglycerin; Posture	1989
Intraoperative heart rate reduction--alinidine versus metoprolol. Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:8 Topics: Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Clonidine; Depression, Chemical; Double-Blind Method; Female; Heart Rate; Humans; Intraoperative Period; Male; Metoprolol; Middle Aged; Random Allocation	1988
Alinidine in heart patients: electrophysiologic and antianginal actions. European heart journal, 1987, Volume: 8 Suppl L Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrophysiology; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Random Allocation; Sinoatrial Node	1987
ST 567 (alinidine) in stable angina: a comparison with metoprolol. European heart journal, 1987, Volume: 8 Suppl L Topics: Angina Pectoris; Anti-Arrhythmia Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Male; Metoprolol; Physical Exertion; Random Allocation	1987
ST 567 compared with propranolol in stable angina. European heart journal, 1987, Volume: 8 Suppl L Topics: Angina Pectoris; Anti-Arrhythmia Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Propranolol; Random Allocation	1987
Value of a specific bradycardic agent in cardiac surgery compared to placebo. European heart journal, 1987, Volume: 8 Suppl L Topics: Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Clonidine; Double-Blind Method; Electrocardiography; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Postoperative Care; Pulmonary Circulation; Random Allocation	1987
Prevention of supraventricular tachyarrhythmias post coronary artery bypass surgery. European heart journal, 1987, Volume: 8 Suppl L Topics: Anti-Arrhythmia Agents; Blood Pressure; Clonidine; Coronary Artery Bypass; Female; Heart Rate; Humans; Male; Middle Aged; Postoperative Complications; Prospective Studies; Random Allocation; Tachycardia, Supraventricular	1987
[Treatment of hyperkinetic heart syndrome with alinidine and propranolol]. Klinische Wochenschrift, 1987, Jan-15, Volume: 65, Issue:2 Topics: Adult; Blood Pressure; Cardiovascular Agents; Clonidine; Echocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Neurocirculatory Asthenia; Propranolol	1987
Safety and efficacy of alinidine in symptom-free asthmatics. European journal of clinical pharmacology, 1986, Volume: 31, Issue:4 Topics: Adult; Asthma; Blood Pressure; Cardiovascular Agents; Clonidine; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Random Allocation; Respiratory Function Tests	1986
Alinidine reduces heart-rate without blockade of beta-adrenoceptors. Lancet (London, England), 1981, Feb-14, Volume: 1, Issue:8216 Topics: Adult; Animals; Cats; Clinical Trials as Topic; Clonidine; Dogs; Double-Blind Method; Heart Rate; Humans; Male; Posture; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta	1981
An assessment of the contribution of clonidine metabolised from alinidine to the cardiovascular effects of alinidine. British journal of clinical pharmacology, 1983, Volume: 16, Issue:4 Topics: Adult; Biotransformation; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Humans; Male; Physical Exertion; Time Factors	1983
Alinidine in angina. Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:6 Topics: Adult; Angina Pectoris; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Random Allocation	1983
Comparative effects of alinidine and propranolol in ischaemic heart disease. European journal of clinical pharmacology, 1982, Volume: 23, Issue:5 Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Coronary Angiography; Coronary Disease; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Posture; Propranolol	1982
Alinidine, a new agent which lowers heart rate in patients with angina pectoris. European heart journal, 1982, Volume: 3, Issue:6 Topics: Aged; Angina Pectoris; Blood Pressure; Cardiovascular Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Male; Middle Aged; Physical Exertion	1982
Acute effects of alinidine on heart rate and blood pressure in healthy subjects and patients with hyperkinetic heart syndrome. European journal of clinical pharmacology, 1983, Volume: 24, Issue:1 Topics: Blood Pressure; Clonidine; Double-Blind Method; Heart Rate; Humans; Male; Neurocirculatory Asthenia; Norepinephrine; Physical Exertion; Propranolol; Random Allocation	1983
Cardiovascular effects of alinidine and propranolol alone and in combination with hydralazine in normal man. British journal of clinical pharmacology, 1983, Volume: 15, Issue:1 Topics: Adult; Blood Pressure; Cardiovascular Agents; Clonidine; Heart Rate; Humans; Hydralazine; Male; Posture; Propranolol	1983
The effect of alinidine (St 567) on emotionally induced tachycardia in man. European journal of clinical pharmacology, 1982, Volume: 21, Issue:6 Topics: Adult; Blood Pressure; Clonidine; Drug Evaluation; Heart Rate; Humans; Male; Stress, Psychological; Tachycardia	1982
Significance of arrhythmias during the first 24 hours of acute myocardial infarction treated with alteplase and effect of early administration of a beta-blocker or a bradycardiac agent on their incidence. Circulation, 1994, Volume: 89, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Clonidine; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Prognosis; Prospective Studies; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator	1994
Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy. Journal of the American College of Cardiology, 1993, Volume: 22, Issue:2 Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Cardiovascular Agents; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency; Ventricular Function, Left	1993

Other Studies

97 other study(ies) available for clonidine and alinidine

Article	Year
Cardiovascular actions of N-allyl-clonidine (ST 567), a substance with specific bradycardic action. European journal of pharmacology, 1979, Sep-15, Volume: 58, Issue:2 Topics: Animals; Behavior, Animal; Blood Pressure; Cardiac Output; Cats; Clonidine; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Time Factors	1979
Imidazoline antagonists of alpha 2-adrenoceptors increase insulin release in vitro by inhibiting ATP-sensitive K+ channels in pancreatic beta-cells. British journal of pharmacology, 1992, Volume: 107, Issue:1 Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antazoline; Clonidine; Electrophysiology; Female; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Phentolamine; Potassium; Potassium Channels; Tolazoline	1992
Capillary growth in the heart. EXS, 1992, Volume: 61 Topics: Animals; Anti-Arrhythmia Agents; Body Weight; Capillaries; Clonidine; Coronary Circulation; Dobutamine; Heart; Muscle, Smooth, Vascular; Myocardial Contraction; Neovascularization, Pathologic; Organ Size; Rabbits; Rats; Rats, Inbred Strains; Reference Values; Stroke Volume	1992
Inhibitory effect of a novel antianginal agent, E4080, on ST segment elevation induced by vasopressin in anesthetized guinea pigs. Japanese journal of pharmacology, 1992, Volume: 60, Issue:2 Topics: Anesthesia; Animals; Benzopyrans; Cardiovascular Agents; Catechols; Clonidine; Coronary Vessels; Cromakalim; Electrocardiography; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isosorbide Dinitrate; Male; Nifedipine; Pyrroles; Vasodilator Agents; Vasopressins	1992
Addition of alinidine, a specific bradycardic agent, to dobutamine in a canine model of endotoxic shock. Critical care medicine, 1992, Volume: 20, Issue:8 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Clonidine; Disease Models, Animal; Dobutamine; Dogs; Drug Evaluation, Preclinical; Drug Therapy, Combination; Escherichia coli Infections; Hemodynamics; Prospective Studies; Random Allocation; Shock, Septic; Time Factors	1992
Effect of the 'specific bradycardic agent' alinidine on the function of ischemic myocardium. The Thoracic and cardiovascular surgeon, 1991, Volume: 39 Suppl 3 Topics: Animals; Anti-Arrhythmia Agents; Cardiovascular Agents; Clonidine; Coronary Circulation; Coronary Disease; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male	1991
Anti-muscarinic effect of alinidine on acetylcholine-induced vasodilation in isolated and perfused dog coronary arteries. The Tohoku journal of experimental medicine, 1991, Volume: 165, Issue:2 Topics: Acetylcholine; Animals; Carbachol; Clonidine; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Parasympatholytics; Piperidines; Pirenzepine; Vasodilation	1991
[Alinidine in multi-vessel coronary disease: reduction of stress-induced ischemic reaction]. Zeitschrift fur Kardiologie, 1991, Volume: 80, Issue:2 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clonidine; Coronary Disease; Electrocardiography; Exercise Test; Heart Conduction System; Heart Rate; Hemodynamics; Humans; Male; Middle Aged	1991
Characterization of responses to cromakalim and pinacidil in smooth and cardiac muscle by use of selective antagonists. British journal of pharmacology, 1990, Volume: 100, Issue:2 Topics: Animals; Aorta, Thoracic; Benzopyrans; Clonidine; Coronary Vessels; Cromakalim; Dogs; Electric Stimulation; Glyburide; Guanidines; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Phentolamine; Pinacidil; Potassium Channels; Pyrroles; Rats	1990
The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats. Journal of immunology (Baltimore, Md. : 1950), 1990, Sep-15, Volume: 145, Issue:6 Topics: Adenosine; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Captopril; Carrageenan; Clonidine; Leukocyte Count; Minoxidil; Neutrophils; Pleurisy; Rats; Receptors, Purinergic; Superoxides; Theophylline	1990
[Sinus node inhibitors in coronary surgery]. Herz, 1990, Volume: 15, Issue:5 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clonidine; Coronary Artery Bypass; Female; Heart Rate; Hemodynamics; Humans; Intraoperative Complications; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic	1990
Hemodynamic effects of alinidine (ST 567) at rest and during exercise in patients with chronic congestive heart failure. American heart journal, 1990, Volume: 119, Issue:6 Topics: Aged; Anti-Arrhythmia Agents; Blood Pressure; Chronic Disease; Clonidine; Exercise; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Rest	1990
Binding of two specific bradycardic agents, alinidine and AQ-A 39, to muscarinic receptors of guinea pig atria and ventricle. Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:2 Topics: Animals; Binding, Competitive; Cardiovascular Agents; Clonidine; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Isoindoles; Myocardium; Phthalimides; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic	1988
Effects of alinidine on metabolic response to high-demand myocardial ischemia. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:3 Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Coronary Disease; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Lactates; Male; Middle Aged; Oxygen Consumption	1989
Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3 Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clonidine; Death, Sudden; Dogs; Electric Stimulation; Electrophysiology; Female; Heart Rate; Male; Ventricular Fibrillation	1989
Alinidine reverses the descending staircase of isolated rat atria by an antimuscarinic action. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Clonidine; Female; Guinea Pigs; Heart; In Vitro Techniques; Ipratropium; Isometric Contraction; Male; Oxotremorine; Papillary Muscles; Parasympatholytics; Rats; Rats, Inbred Strains	1989
Mechanisms of chronotropic cardiac effects of alinidine and plasma concentration-response relationships in the conscious dog with chronic atrioventricular block. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Clonidine; Dogs; Drug Interactions; Electrocardiography; Female; Heart Block; Heart Rate; Male; Phenoxybenzamine; Phentolamine; Receptors, Muscarinic; Yohimbine	1989
[Alindine reduces decreased ventricular conduction induced by large doses of bupivacaine in the anesthetized dog]. Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl Topics: Anesthesia; Animals; Bupivacaine; Clonidine; Dogs; Heart Conduction System	1989
Comparative study of cardiovascular effects of clonidine and alinidine in cross-perfused dog atrial preparations. Japanese heart journal, 1989, Volume: 30, Issue:6 Topics: Animals; Cardiovascular Agents; Clonidine; Cross Circulation; Dogs; Heart; Heart Rate; Myocardial Contraction; Parasympatholytics	1989
Alinidine antagonizes the myocardial effects of adenosine. European journal of pharmacology, 1989, May-02, Volume: 164, Issue:1 Topics: Action Potentials; Adenosine; Animals; Atropine; Cardiovascular Agents; Clonidine; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Rats	1989
Circadian rhythm of heart rate in the rabbit: prolongation of action potential duration by sustained beta adrenoceptor blockade is not due to associated bradycardia. Cardiovascular research, 1986, Volume: 20, Issue:7 Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Bradycardia; Circadian Rhythm; Clonidine; Heart; Heart Rate; Nadolol; Rabbits	1986
Effect of ST-567 (a specific bradycardiac agent) in patients with unstable angina and myocardial infarction. European heart journal, 1987, Volume: 8 Suppl L Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Anti-Arrhythmia Agents; Clonidine; Heart Rate; Hemodynamics; Humans; Myocardial Infarction	1987
[Hemodynamic effects of alinidine in the early postoperative phase of cardiac surgery]. Presse medicale (Paris, France : 1983), 1988, Oct-29, Volume: 17, Issue:38 Topics: Adult; Aged; Cardiovascular Agents; Clonidine; Female; Heart Diseases; Hemodynamics; Humans; Male; Middle Aged; Postoperative Period; Time Factors	1988
Characterization of guinea-pig cardiac muscarinic receptors by radioligand dissociation kinetics. European journal of pharmacology, 1988, Jul-07, Volume: 151, Issue:2 Topics: Allosteric Site; Animals; Clonidine; Female; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Isoindoles; Kinetics; Male; Myocardium; Phthalimides; Radioligand Assay; Receptors, Muscarinic	1988
Effects of alinidine on survival and infarct size in rats with coronary artery occlusion. European journal of pharmacology, 1988, Nov-15, Volume: 157, Issue:1 Topics: Animals; Blood Pressure; Clonidine; Heart Rate; Male; Myocardial Infarction; Rats	1988
Bradycardic effects of AQ-A 39 (falipamil) in situ and in isolated, blood-perfused dog hearts. Comparison with alinidine and verapamil. Japanese heart journal, 1988, Volume: 29, Issue:6 Topics: Animals; Cardiovascular Agents; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart; Heart Atria; Heart Rate; Isoindoles; Myocardial Contraction; Phthalimides; Verapamil	1988
Acute haemodynamic effects of a specific bradycardic agent in patients with coronary heart disease and impaired left ventricular function. European heart journal, 1987, Volume: 8 Suppl L Topics: Anti-Arrhythmia Agents; Clonidine; Coronary Disease; Female; Heart Rate; Hemodynamics; Humans; Male; Myocardial Contraction	1987
Antiarrhythmic action of specific bradycardic agents. European heart journal, 1987, Volume: 8 Suppl L Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clonidine; Heart Rate; Humans	1987
Alinidine as a model of the mode of action of specific bradycardic agents on SA node activity. European heart journal, 1987, Volume: 8 Suppl L Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Clonidine; Female; Heart Rate; In Vitro Techniques; Isoindoles; Male; Membrane Potentials; Myocardial Contraction; Phthalimides; Rabbits; Sinoatrial Node	1987
Pharmacological influence of specific bradycardic agents on the pacemaker current of sheep cardiac Purkinje fibres. A comparison between three different molecules. European heart journal, 1987, Volume: 8 Suppl L Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzazepines; Clonidine; Heart Conduction System; Heart Rate; In Vitro Techniques; Isoindoles; Myocardial Contraction; Phthalimides; Purkinje Fibers; Sheep	1987
Changes in systemic haemodynamics, regional myocardial function and perfusion induced by alinidine in pigs with and without narrowed coronary arteries. European heart journal, 1987, Volume: 8 Suppl L Topics: Animals; Anti-Arrhythmia Agents; Clonidine; Constriction; Coronary Circulation; Coronary Vessels; Heart Rate; Hemodynamics; Imidazoles; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Swine	1987
Effects of specific bradycardic agents on exercise-induced regional myocardial dysfunction in dogs. European heart journal, 1987, Volume: 8 Suppl L Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Clonidine; Coronary Disease; Depression, Chemical; Dogs; Heart Rate; Myocardial Contraction; Physical Exertion; Propranolol	1987
The clinical pharmacology of alinidine and its side-effects. European heart journal, 1987, Volume: 8 Suppl L Topics: Anti-Arrhythmia Agents; Blood Pressure; Clonidine; Drug Evaluation; Heart Rate; Humans; Random Allocation; Sleep Stages; Vision Disorders	1987
Assessment of the bradycardic and inotropic properties of ST 567 using a new scheme of administration. European heart journal, 1987, Volume: 8 Suppl L Topics: Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Output; Clonidine; Female; Heart Rate; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction	1987
Investigations differentiating the mechanism of specific bradycardic agents from that of calcium channel blockers. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:3 Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Clonidine; Electrophysiology; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoindoles; Myocardial Contraction; Phthalimides; Sinoatrial Node; Verapamil	1987
Crystal and molecular structure of 2-[N-allyl-N-(2,6-dichlorophenyl)amino]-2-imidazoline hydrobromide. Archiv der Pharmazie, 1987, Volume: 320, Issue:6 Topics: Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Clonidine; Crystallization; Molecular Conformation; X-Ray Diffraction	1987
Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Archiv : European journal of physiology, 1987, Volume: 410, Issue:1-2 Topics: Action Potentials; Animals; Biological Clocks; Cardiovascular Agents; Clonidine; Heart Conduction System; In Vitro Techniques; Iontophoresis; Kinetics; Membrane Potentials; Purkinje Fibers; Sheep	1987
Blocking effects of alinidine on negative chronotropic and inotropic responses to vagal stimulation and injected acetylcholine and carbachol in dogs. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3 Topics: Acetylcholine; Adenosine; Animals; Atropine; Carbachol; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Heart Rate; Myocardial Contraction; Vagus Nerve	1987
Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells. European journal of pharmacology, 1986, Feb-18, Volume: 121, Issue:2 Topics: Action Potentials; Animals; Cardiovascular Agents; Clonidine; Depression, Chemical; Diastole; Dose-Response Relationship, Drug; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Rabbits; Sinoatrial Node	1986
Is reduced cardiac performance the only mechanism for myocardial infarct size reduction during beta adrenergic blockade? Cardiovascular research, 1986, Volume: 20, Issue:5 Topics: Animals; Autoradiography; Cardiac Output; Cats; Clonidine; Disease Models, Animal; Heart Rate; Myocardial Infarction; Myocardium; Random Allocation; Timolol	1986
Further studies of alinidine induced bradycardia in the presence of caesium. Cardiovascular research, 1986, Volume: 20, Issue:5 Topics: Animals; Cesium; Clonidine; Female; Heart Rate; In Vitro Techniques; Male; Membrane Potentials; Rabbits; Sinoatrial Node	1986
Effects of alinidine on exercise-induced regional contractile dysfunction in dogs. European journal of pharmacology, 1986, Oct-14, Volume: 130, Issue:1-2 Topics: Animals; Cardiovascular Agents; Clonidine; Dogs; Female; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Physical Exertion; Time Factors	1986
Electrophysiological effects of alinidine (ST 567) on sinoatrial node fibres in the rabbit heart. Cardiovascular research, 1986, Volume: 20, Issue:10 Topics: Acetylcholine; Action Potentials; Animals; Cesium; Chlorine; Clonidine; Depression, Chemical; Epinephrine; Female; Heart Rate; Male; Rabbits; Sinoatrial Node; Time Factors	1986
Can exercise-induced regional contractile dysfunction be prevented by selective bradycardic agents? Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Benzazepines; Cardiovascular Agents; Clonidine; Dogs; Hemodynamics; Male; Myocardial Contraction; Physical Exertion; Propranolol	1986
Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction. The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 2 Topics: Acetylcholine; Animals; Atrioventricular Node; Atropine; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; Male; Norepinephrine; Parasympathetic Nervous System; Parasympatholytics; Premedication; Propranolol; Sinoatrial Node; Stellate Ganglion; Time Factors; Vagus Nerve	1985
Antifibrillatory properties of alinidine after coronary artery occlusion in rats. European journal of pharmacology, 1985, Apr-16, Volume: 110, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Clonidine; Coronary Disease; Electrocardiography; Heart Rate; Hemodynamics; Male; Mexiletine; Rats; Rats, Inbred Strains; Risk; Ventricular Fibrillation	1985
Anion-channel blockade with alinidine: a specific bradycardic drug for coronary heart disease without negative inotropic activity? The American journal of cardiology, 1985, Aug-01, Volume: 56, Issue:4 Topics: Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Cardiotonic Agents; Clonidine; Coronary Disease; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Contraction	1985
Chronotropic action of alinidine on the isolated sinus node of the rabbit heart. European heart journal, 1985, Volume: 6, Issue:9 Topics: Action Potentials; Animals; Clonidine; Depression, Chemical; Heart Conduction System; Heart Rate; In Vitro Techniques; Membrane Potentials; Rabbits; Sinoatrial Node; Time Factors	1985
Properties of alinidine. Lancet (London, England), 1981, Mar-14, Volume: 1, Issue:8220 Pt 1 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clonidine; Hemodynamics; Humans	1981
Anion antagonism--a fifth class of antiarrhythmic action? Lancet (London, England), 1981, Jun-13, Volume: 1, Issue:8233 Topics: Anions; Arrhythmias, Cardiac; Cations; Clonidine; Humans; Ion Channels; Myocardial Contraction	1981
A fifth class of antiarrhythmic action? Lancet (London, England), 1981, Jul-25, Volume: 2, Issue:8239 Topics: Anti-Arrhythmia Agents; Calcium; Clonidine; Humans; Sinoatrial Node	1981
Effect of alinidine (St 567) on sympathetic and vagal activities. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 255, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Male; Pressoreceptors; Sympathetic Nervous System; Vagus Nerve	1982
Characterization of the clonidine receptor site. Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Animals; Blood Pressure; Brain; Clonidine; Feedback; Guinea Pigs; Heart Rate; Norepinephrine; Phentolamine; Pressoreceptors; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex; Sinoatrial Node; Stimulation, Chemical; Synapses	1983
Principles of therapy for congestive heart failure. European heart journal, 1983, Volume: 4 Suppl A Topics: Calcium; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Clonidine; Cyclic AMP; Cytosol; Digitalis Glycosides; Diuretics; Heart Failure; Humans; Ketanserin; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocardium; Myosins; Piperidines; Receptors, Adrenergic, alpha; Vasodilator Agents	1983
Effect of indoramin, labetalol and alinidine on sympathetic function in normal man. British journal of clinical pharmacology, 1984, Volume: 18, Issue:2 Topics: Adolescent; Adult; Blood Pressure; Clonidine; Ethanolamines; Heart Rate; Humans; Indoles; Indoramin; Labetalol; Male; Norepinephrine; Posture; Renin; Sympathetic Nervous System	1984
Selectivity of alinidine, a bradycardic agent, for SA nodal automaticity versus other cardiac activities in isolated, blood-perfused dog-heart preparations. Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 272, Issue:1 Topics: Animals; Atrioventricular Node; Cardiovascular Agents; Clonidine; Coronary Circulation; Dogs; Female; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Sinoatrial Node	1984
Decrease in bradycardic effect of AQ-A 39 and alinidine in guinea-pig sinoatrial node depolarized by high external K+-concentration. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 328, Issue:2 Topics: Animals; Clonidine; Depression, Chemical; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoindoles; Neuromuscular Depolarizing Agents; Phthalimides; Potassium; Sinoatrial Node; Verapamil	1984
Interactions between alinidine and responses to acetylcholine, dopamine and 5-hydroxytryptamine of specific Helix central neurones. British journal of pharmacology, 1983, Volume: 80, Issue:3 Topics: Acetylcholine; Action Potentials; Animals; Brain; Cardiovascular Agents; Clonidine; Dopamine; Helix, Snails; Neurons; Serotonin; Sodium	1983
Pharmacological mapping of regional effects in the rabbit heart of some new antiarrhythmic drugs. British journal of pharmacology, 1983, Volume: 79, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Butyrophenones; Clonidine; Dose-Response Relationship, Drug; Heart; Heart Conduction System; Heart Rate; Imidazoles; In Vitro Techniques; Rabbits	1983
Electrophysiological effects of alinidine on nodal and atrial fibers in the guinea-pig heart. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:2 Topics: Action Potentials; Animals; Cardiovascular Agents; Clonidine; Diastole; Female; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Sinoatrial Node	1984
Haemodynamic effects of alinidine, a specific sinus node inhibition, in patients with unstable angina or myocardial infarction. European heart journal, 1984, Volume: 5, Issue:3 Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Cardiac Output; Cardiovascular Agents; Clonidine; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction	1984
Relative roles of heart rate and ventricular stroke volume for the regulation of cardiac output during controlled hypotension with sodium nitroprusside in man. European journal of clinical investigation, 1982, Volume: 12, Issue:1 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiovascular Agents; Clonidine; Ferricyanides; Heart Rate; Humans; Hypotension, Controlled; Middle Aged; Nitroprusside; Stroke Volume	1982
Comparison of the bradycardic effects of alinidine (St 567), AQ-A 39 and verapamil on guinea-pig sinoatrial node superfused with different Ca2+ and NaCl solutions. European journal of pharmacology, 1983, Jan-28, Volume: 87, Issue:1 Topics: Animals; Calcium; Clonidine; Electrophysiology; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoindoles; Male; Phthalimides; Sinoatrial Node; Sodium Chloride; Verapamil	1983
Inhibition of positive chronotropic effects of PGE2 by alinidine. European journal of pharmacology, 1982, Feb-19, Volume: 78, Issue:1 Topics: Animals; Clonidine; Dinoprostone; Epinephrine; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Prostaglandins E	1982
Effect of dobutamine on cardiac function in man: reciprocal roles of heart rate and ventricular stroke volume. Critical care medicine, 1982, Volume: 10, Issue:6 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiovascular Agents; Catecholamines; Clonidine; Dobutamine; Drug Interactions; Heart Rate; Humans; Middle Aged; Stroke Volume; Surgical Procedures, Operative	1982
Alinidine pharmacokinetics following acute and chronic dosing. British journal of clinical pharmacology, 1982, Volume: 13, Issue:6 Topics: Adult; Clonidine; Humans; Kinetics; Male; Time Factors	1982
Cardiovascular effects of N-allyl clonidine (ST 567, alinidine): a substance with specific bradycardiac action during neuroleptanesthesia in humans. International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:9 Topics: Adult; Aged; Blood Pressure; Cardiovascular Agents; Clonidine; Heart Rate; Hemodynamics; Humans; Middle Aged; Neuroleptanalgesia; Nitroprusside	1982
Effects of alinidine (ST 567) on baroreceptor-heart rate reflexes and its interactions with clonidine on the baroreflex and on the sympathetic terminals of the isolated atrium. European journal of pharmacology, 1982, Oct-22, Volume: 84, Issue:3-4 Topics: Animals; Clonidine; Drug Interactions; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Nerve Endings; Nitroprusside; Pressoreceptors; Rabbits; Reflex; Sympathetic Nervous System	1982
Effects of alinidine on myocardial contraction and relaxation. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 259, Issue:2 Topics: Animals; Cardiovascular Agents; Cats; Clonidine; In Vitro Techniques; Muscle Relaxation; Myocardial Contraction; Papillary Muscles; Sarcoplasmic Reticulum	1982
The effects of the bradycardia-producing compound alinidine on action potentials and tension development in cardiac fibres. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:2 Topics: Action Potentials; Animals; Barium; Bradycardia; Calcium; Cardiovascular Agents; Chick Embryo; Clonidine; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Muscle Tonus; Papillary Muscles	1981
Determination of alinidine in human plasma by high-performance liquid chromatography. Journal of chromatography, 1981, Apr-10, Volume: 223, Issue:1 Topics: Administration, Oral; Chromatography, High Pressure Liquid; Clonidine; Half-Life; Humans; Injections, Intravenous; Reference Values	1981
A preliminary cardiovascular assessment of alinidine. British journal of clinical pharmacology, 1981, Volume: 11, Issue:4 Topics: Adult; Blood Pressure; Clonidine; Electrocardiography; Heart Rate; Hemodynamics; Humans; Male; Myocardial Contraction	1981
[Hemodynamic actions on alinidine during exercise in patients with coronary artery disease]. Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:5 Topics: Clonidine; Coronary Disease; Electrocardiography; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Physical Exertion	1981
Development and quality control of a highly sensitive radioimmunoassay for alinidine. Journal of pharmacological methods, 1981, Volume: 6, Issue:2 Topics: Animals; Antibodies; Body Fluids; Clonidine; Dogs; Female; Haptens; Quality Control; Rabbits; Radioimmunoassay	1981
Pacemaker selectivity: influence on rabbit atria of ionic environment and of alinidine, a possible anion antagonist. Cardiovascular research, 1981, Volume: 15, Issue:6 Topics: Animals; Atrial Function; Atropine; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Electrolytes; Female; Heart Atria; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Rabbits; Sinoatrial Node	1981
Pharmacokinetics and metabolism of 14C-labelled alinidine in man and dogs. European journal of drug metabolism and pharmacokinetics, 1981, Volume: 6, Issue:3 Topics: Administration, Oral; Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Cardiovascular Agents; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Clonidine; Dogs; Female; Humans; Injections, Intravenous; Kinetics; Male; Mass Spectrometry	1981
The effects of drugs on the exercise electrocardiogram. Cardiology, 1981, Volume: 68 Suppl 2 Topics: Cardiovascular Agents; Clonidine; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Propranolol; Vasodilator Agents; Verapamil	1981
Proof of the linearity of the pharmacokinetics of alinidine in man. European journal of clinical pharmacology, 1981, Volume: 21, Issue:3 Topics: Administration, Oral; Adult; Cardiovascular Agents; Clonidine; Humans; Kinetics; Male; Models, Biological; Radioimmunoassay	1981
New aspects in the metabolism of alinidine in man. European journal of drug metabolism and pharmacokinetics, 1981, Volume: 6, Issue:4 Topics: Cardiovascular Agents; Clonidine; Humans	1981
The effects of alinidine, an N-allyl derivative of clonidine, on regional myocardial perfusion and performance in the pig with or without atrial pacing. European journal of pharmacology, 1980, Jun-27, Volume: 64, Issue:4 Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular Agents; Cerebrovascular Circulation; Clonidine; Coronary Circulation; Electrocardiography; Heart; Heart Rate; Hemodynamics; Kidney; Myocardial Contraction; Oxygen Consumption; Pacemaker, Artificial; Perfusion; Stroke Volume; Swine; Vascular Resistance	1980
Haemodynamic and electrophysiologic actions of alinidine in the dog. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:1 Topics: Animals; Cardiac Pacing, Artificial; Clonidine; Dogs; Electroencephalography; Electrophysiology; Heart; Heart Rate; Hemodynamics; Myocardium; Oxygen Consumption	1980
Modulation of EPSP shape and efficacy by intrinsic membrane conductances in rat neocortical pyramidal neurons in vitro. The Journal of physiology, 1993, Volume: 468 Topics: Animals; Cesium; Clonidine; Electric Conductivity; Evoked Potentials; In Vitro Techniques; Ion Channels; Lidocaine; Membrane Potentials; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Visual Cortex	1993
Effects of Zeneca ZD7288 in comparison with alinidine and UL-FS 49 on guinea pig sinoatrial node and ventricular action potentials. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3 Topics: Action Potentials; Animals; Benzazepines; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Papillary Muscles; Pyrimidines; Sinoatrial Node	1994
Inhibitory actions of ZENECA ZD7288 on whole-cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells. British journal of pharmacology, 1993, Volume: 110, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzazepines; Cardiovascular Agents; Clonidine; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Pyrimidines; Sinoatrial Node	1993
Cardiac electrophysiologic effects of alinidine, a specific bradycardic agent, in the conscious dog: plasma concentration-response relations. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Blood Pressure; Bundle of His; Cardiovascular Agents; Clonidine; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Heart Rate; Injections, Intravenous; Male; Sinoatrial Node	1995
Alinidine prevents hypoperfusion-induced transmural flow redistribution in isolated paced rat hearts. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:6 Topics: Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Coronary Circulation; Heart; In Vitro Techniques; Male; Microspheres; Myocardial Contraction; Rats; Rats, Inbred Strains; Ventricular Pressure	1994
Comparison of the cromakalim antagonism and bradycardic actions of a series of novel alinidine analogues in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:2 Topics: Animals; Benzopyrans; Cardiovascular Agents; Clonidine; Cromakalim; Heart Rate; In Vitro Techniques; Male; Potassium Channels; Pyrroles; Rats; Structure-Activity Relationship	1994
Electropharmacology of the bradycardic agents alinidine and zatebradine (UL-FS 49) in a conscious canine ventricular arrhythmia model of permanent coronary artery occlusion. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Blood Pressure; Cardiotonic Agents; Clonidine; Coronary Vessels; Dogs; Electric Stimulation; Electrocardiography; Electrophysiology; Evoked Potentials; Female; Male; Myocardial Infarction; Refractory Period, Electrophysiological; Tachycardia, Ventricular	1995
Cardiac electrophysiological effects of falipamil in the conscious dog: comparison with alinidine. European journal of pharmacology, 1996, Jun-13, Volume: 306, Issue:1-3 Topics: Animals; Atrioventricular Node; Blood Pressure; Bundle of His; Cardiovascular Agents; Clonidine; Dogs; Electroencephalography; Electrophysiology; Female; Heart; Heart Rate; Isoindoles; Male; Phthalimides; Sinoatrial Node	1996
The novel cardioprotective agent BMS-180448 activates a potassium conductance in cardiac and vascular smooth muscle. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:4 Topics: Animals; Aorta, Thoracic; Benzopyrans; Cardiotonic Agents; Cardiovascular Agents; Cells, Cultured; Clonidine; Glyburide; Guanidines; Guinea Pigs; Heart Ventricles; Male; Muscle, Smooth, Vascular; Myocardium; Patch-Clamp Techniques; Potassium Channels; Rabbits; Rubidium Radioisotopes	1996
Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Pacing, Artificial; Cardiovascular Agents; Clonidine; Heart; Male; Potassium Channel Blockers; Rats; Rats, Inbred WKY; Reperfusion Injury; Structure-Activity Relationship	1997
Heterogeneous characteristics of imidazoline-induced insulin secretion. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Calcium; Clonidine; Drug Interactions; Enzyme Inhibitors; Glucose; Idazoxan; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Phentolamine; Potassium Channels; Time Factors	1999
Bradycardia-induced coronary angiogenesis is dependent on vascular endothelial growth factor. Circulation research, 1999, Jul-23, Volume: 85, Issue:2 Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Antibodies; Blotting, Northern; Blotting, Western; Body Weight; Bradycardia; Capillaries; Clonidine; Coronary Vessels; Endothelial Growth Factors; Fibroblast Growth Factor 2; Gene Expression; Heart Rate; Lymphokines; Male; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Ventricular Function, Left	1999
The identification of a potent imidazoline-based vascular K(ATP) channel antagonist. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Cattle; Clonidine; Coronary Vessels; Cromakalim; Glyburide; Guanidines; Heart Atria; Heart Rate; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; KATP Channels; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Radioligand Assay; Rats; Swine; Vasodilator Agents	2000
Bradycardia induces angiogenesis, increases coronary reserve, and preserves function of the postinfarcted heart. Circulation, 2004, Aug-17, Volume: 110, Issue:7 Topics: Angiopoietin-1; Angiopoietin-2; Animals; Bradycardia; Cardiovascular Agents; Clonidine; Coronary Vessels; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Heart Ventricles; Hypertrophy, Left Ventricular; Ligation; Male; Models, Animal; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Stroke Volume; Ultrasonography; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2	2004
Reduction of heart rate by chronic beta1-adrenoceptor blockade promotes growth of arterioles and preserves coronary perfusion reserve in postinfarcted heart. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Arterioles; Atenolol; Cardiac Output; Clonidine; Coronary Vessels; Diastole; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Stroke Volume	2005
Control of catecholamine-induced tachycardia with alinidine in the anesthetized dog. Journal of cardiothoracic anesthesia, 1987, Volume: 1, Issue:4 Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Clonidine; Dobutamine; Dogs; Heart Rate; Isoproterenol; Tachycardia, Sinus	1987