clonidine and alfentanil

clonidine has been researched along with alfentanil in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's8 (38.10)18.2507
2000's9 (42.86)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Duncan, SR; Jarvis, DA; Maze, M; Segal, IS1
Eddy, AC; Hill, HF; Kharasch, ED1
Duncan, SR; Jarvis, DJ; Maze, M; Segal, IS; White, PF1
Jarvis, AP; Prys-Roberts, C; Richards, MJ; Skues, MA1
Bellens, B; de Rood, M; Engelman, E; Gilbart, E; Lipszyc, M; Van der Linden, P; Van Romphey, A1
Abi-Jaoude, F; Brusset, A; Ceddaha, A; Dubois, C; Fischler, M; Guilmet, D; Raffin, L; Schlumberger, S1
Detweiler, D; Eisenach, J; Hood, D1
Bayon, MC; Boucaud, C; Bouilloc, X; Brudon, JR; Butin, E; Danays, T; Frehring, B; Ghignone, M; Levron, JC; Petit, P; Quintin, L; Tassan, H; Tissot, S; Viale, JP1
Bause, H; Möllenberg, O; Prause, A; Scholz, J; Schulte am Esch, J; Wappler, F1
Caldwell, JE; Heier, T; Richardson, CA; Talke, PO1
Bermejo, S; Fernandez-Galinski, S; Mansilla, R; Pol, O; Puig, MM1
Arici, G; Erman, M; Ertugrul, F; Karsli, B; Kayacan, N; Nacitarhan, C; Sadan, G1
Alfonsi, P; Chauvin, M; Gaude-Joindreau, V; Guignard, B; Passard, A; Sessler, DI1

Reviews

1 review(s) available for clonidine and alfentanil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

9 trial(s) available for clonidine and alfentanil

ArticleYear
Ventilatory effects of clonidine alone and in the presence of alfentanil, in human volunteers.
    Anesthesiology, 1992, Volume: 76, Issue:6

    Topics: Adult; Alfentanil; Clonidine; Depression, Chemical; Humans; Male; Respiration

1992
Clinical efficacy of oral-transdermal clonidine combinations during the perioperative period.
    Anesthesiology, 1991, Volume: 74, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Cutaneous; Administration, Oral; Adult; Aged; Alfentanil; Anesthesia, Intravenous; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Morphine; Pain, Postoperative; Surgical Procedures, Operative

1991
Total i.v. anaesthesia with propofol and alfentanil: dose requirements for propofol and the effect of premedication with clonidine.
    British journal of anaesthesia, 1990, Volume: 65, Issue:2

    Topics: Administration, Oral; Alfentanil; Anesthesia, Intravenous; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Preanesthetic Medication; Propofol; Temazepam

1990
Effects of clonidine on anesthetic drug requirements and hemodynamic response during aortic surgery.
    Anesthesiology, 1989, Volume: 71, Issue:2

    Topics: Aged; Alfentanil; Anesthesia, Intravenous; Anesthetics; Aorta; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Droperidol; Fentanyl; Heart Rate; Hemodynamics; Humans; Intraoperative Period; Middle Aged; Norepinephrine; Preanesthetic Medication; Random Allocation

1989
Clonidine premedication for coronary artery bypass grafting under high-dose alfentanil anesthesia: intraoperative and postoperative hemodynamic study.
    Journal of cardiothoracic and vascular anesthesia, 1993, Volume: 7, Issue:1

    Topics: Alfentanil; Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Clonidine; Coronary Artery Bypass; Dobutamine; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypotension; Male; Middle Aged; Monitoring, Intraoperative; Placebos; Postoperative Care; Preanesthetic Medication; Pulmonary Wedge Pressure; Time Factors; Vascular Resistance

1993
Clonidine for major vascular surgery in hypertensive patients: a double-blind, controlled, randomized study.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Administration, Oral; Adult; Alfentanil; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; Aortic Diseases; Blood Circulation; Cardiotonic Agents; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Intraoperative Care; Isoflurane; Isoproterenol; Male; Midazolam; Middle Aged; Placebos; Premedication; Vasoconstrictor Agents

1996
The effects of clonidine on human digital vasculature.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adult; Alfentanil; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Clonidine; Consciousness; Cross-Over Studies; Female; Fingers; Heart Rate; Humans; Infrared Rays; Injections, Intravenous; Male; Middle Aged; Monitoring, Physiologic; Nitrous Oxide; Plethysmography; Propofol; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents

2000
Comparative assessment of the effects of alfentanil, esmolol or clonidine when used as adjuvants during induction of general anaesthesia.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:6

    Topics: Adjuvants, Anesthesia; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Alfentanil; Analgesics; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Clonidine; Double-Blind Method; Electroencephalography; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Propanolamines

2004
Nefopam and alfentanil additively reduce the shivering threshold in humans whereas nefopam and clonidine do not.
    Anesthesiology, 2009, Volume: 111, Issue:1

    Topics: Adult; Alfentanil; Body Temperature; Clonidine; Drug Synergism; Humans; Male; Nefopam; Shivering; Single-Blind Method; Young Adult

2009

Other Studies

11 other study(ies) available for clonidine and alfentanil

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Influence of dexmedetomidine and clonidine on human liver microsomal alfentanil metabolism.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: Adrenergic alpha-Agonists; Alfentanil; Biotransformation; Clonidine; Humans; Imidazoles; In Vitro Techniques; Medetomidine; Microsomes, Liver; Regression Analysis

1991
Hemodynamic and analgesic actions of epidurally administered clonidine.
    Anesthesiology, 1993, Volume: 78, Issue:2

    Topics: Alfentanil; Clonidine; Depression, Chemical; Epidural Space; Epinephrine; Hemodynamics; Humans; Infusions, Intravenous; Norepinephrine; Pain; Respiration

1993
[Level concept of analgesic dosing in intensive care medicine with sufentanil].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1998, Volume: 33, Issue:1

    Topics: Alfentanil; Analgesics, Opioid; Carbon Dioxide; Clonidine; Critical Care; Dose-Response Relationship, Drug; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intubation; Midazolam; Morphine; Respiration; Respiration, Artificial; Retrospective Studies; Sufentanil; Sympatholytics

1998
The effects of opioids, local anesthetics and adjuvants on isolated pregnant rat uterine muscles.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:4

    Topics: Alfentanil; Amides; Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Female; Isometric Contraction; Meperidine; Mepivacaine; Midazolam; Myometrium; Oxytocics; Oxytocin; Piperidines; Pregnancy; Rats; Rats, Wistar; Remifentanil; Ropivacaine; Uterine Contraction

2007