clonidine has been researched along with adenosine in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (58.97) | 18.7374 |
| 1990's | 16 (20.51) | 18.2507 |
| 2000's | 10 (12.82) | 29.6817 |
| 2010's | 6 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ahn, HS; Makman, MH | 1 |
| Stone, TW; Taylor, DA | 2 |
| Boer, PH; Fekkes, D; Korf, J | 1 |
| Kleefeld, G; Schultz, J | 1 |
| Marshall, HW; Stoner, HB | 1 |
| Callanan, K; Keenan, AK | 1 |
| Kirkpatrick, JR; Phillis, JW | 1 |
| Coupar, IM; Dionyssopoulos, T; Hope, W | 1 |
| Bak, JF; Møller-Pedersen, T; Pedersen, SB; Richelsen, B | 1 |
| Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z | 1 |
| Gilbertsen, RB; Lesch, ME; Schrier, DJ; Wright, CD | 1 |
| Edens, NK; Hirsch, J; Leibel, RL | 1 |
| Baron, C; Hasni, H; Laborit, H; Manzo-Fay, G | 1 |
| Aran, S; Proudfit, HK | 1 |
| Holtzman, SG | 1 |
| Baldwin, HA; File, SE | 1 |
| Hori, M; Inoue, M; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Tamai, J | 1 |
| Gotoh, K; Hori, M; Inoue, M; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H | 1 |
| Kendall, DA; Robinson, JP | 1 |
| De Sarro, A; De Sarro, GB | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Hajimohammadreza, I; Mantzouridis, T; Xiang, JZ | 1 |
| Lang, U; Streller, I; Walland, A | 1 |
| Hori, M; Inoue, M; Iwai, K; Iwakura, K; Kagiya, T; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Fujiwara, Y; Kazahaya, Y; Otsuki, S; Sandyk, R; Takeda, T | 1 |
| Furukawa, T; Inoue, T; Katsuragi, T | 1 |
| Fischer, B; Kather, H; Schlierf, G; Wieland, E; Wirth, A | 1 |
| Paul, SM; Wolkowitz, OM | 1 |
| Birch, PJ; Fillenz, M | 1 |
| Doak, N; Fleming, WW; Leedham, JA; Taylor, DA | 1 |
| Bloomfield, MR; Fillenz, M | 1 |
| Bertrand, G; Gross, R; Loubatières-Mariani, MM; Ribes, G | 1 |
| Kharin, NA; Komissarov, IV; Serdiuk, SE | 1 |
| Joost, C; Kather, H; Scheurer, A; Vogel, G; Wieland, E; Wildenberg, U | 1 |
| DeLander, GE; Hopkins, CJ | 1 |
| Coffin, VL; Spealman, RD | 1 |
| Benishin, CG; Cooper, JR; Pearce, LB | 2 |
| Chiba, S; Furukawa, Y; Ogiwara, Y; Takeda, M | 1 |
| Collier, HO; Tucker, JF | 1 |
| Furukawa, T; Katsuragi, T; Ushijima, I | 1 |
| Watanabe, Y; Yoshida, H | 1 |
| Boulenger, JP; Uhde, TW | 1 |
| Honeyman, TW; McMahon, KK; Schimmel, RJ | 1 |
| Galloway, MP; Roth, RH | 1 |
| McMahon, KK; Schimmel, RJ | 1 |
| Fain, JN; Garcia-Sainz, JA; Li, SY | 1 |
| Berlan, M; Carpene, C; Lafontan, M | 1 |
| Kamino, Y; Lai, RT; Watanabe, Y; Yoshida, H | 1 |
| Kagiya, T; Kaminoh, Y; Kawabata, H; Watanabe, Y; Yoshida, H | 1 |
| Kulkarni, SK; Mehta, AK | 1 |
| Ishii, K; Kato, R; Yamamoto, S | 1 |
| Katsuragi, T; Su, C | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Carter, MF; Deutsch, SI; Jacobson, KA; Lin, RC; Mastropaolo, J; Meshulam, Y; Von Lubitz, DK | 1 |
| Bjur, RA; Hashimoto, M; Hattori, K; Masumura, S; Shinozuka, K; Westfall, DP | 1 |
| Hoffman, BB; Reaven, GM; Swislocki, AL; Vestal, RE | 1 |
| Aley, KO; Levine, JD | 1 |
| Caicedo, M; Cepelík, J; Dedina, M; Hynie, S | 1 |
| Chiari, AI; Eisenach, JC | 1 |
| Foldes, FF; Matkó, I; Nagashima, H; Oe, K; Sántha, E; Sperlágh, B; Vizi, ES | 1 |
| Capecchi, PL; Colafati, M; Di Perri, T; Pasini, FL; Puccetti, L; Randisi, P | 1 |
| Kyselá, S; Török, J | 1 |
| Kubota, Y; Kunitomo, M; Kwon, YM; Nakamura, K; Shinozuka, K; Tanaka, N; Tanioka, Y | 1 |
| Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ | 1 |
| Dinenno, FA; Fritzlar, SJ; Joyner, MJ; Rosenmeier, JB | 1 |
| Dinenno, FA; Joyner, MJ | 1 |
| Dinenno, FA; Joyner, MJ; Masuki, S | 1 |
| Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F | 1 |
| Dussor, G; Fields, HL; Gutierrez, T; King, T; Lai, J; Porreca, F; Vanderah, TW; Vera-Portocarrero, L | 1 |
| Ewan, EE; Martin, TJ | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Mansoori, E; Moezi, L; Niknahad, H; Shafaroodi, H | 1 |
| Eisenach, JC; North, J; Rauck, RL | 1 |
4 review(s) available for clonidine and adenosine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Neural and molecular mechanisms in anxiety.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Carbolines; Clonidine; Disease Models, Animal; Forecasting; Haplorhini; Humans; Locus Coeruleus; Piperoxan; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Research Design; Yohimbine | 1985 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
[Biochemical aspects of anxiety].
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Catecholamines; Central Nervous System; Clonidine; Hormones; Humans; Locus Coeruleus; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
4 trial(s) available for clonidine and adenosine
| Article | Year |
|---|---|
Exogenous NO administration and alpha-adrenergic vasoconstriction in human limbs.
Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Clonidine; Extremities; Forearm; Humans; Laser-Doppler Flowmetry; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phenylephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Tyramine; Vasoconstriction; Vasodilator Agents | 2003 |
Combined NO and PG inhibition augments alpha-adrenergic vasoconstriction in contracting human skeletal muscle.
Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Blood Pressure; Clonidine; Humans; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Norepinephrine; Phenylephrine; Prostaglandins; Receptors, Adrenergic, alpha; Regional Blood Flow; Sympathetic Nervous System; Tyramine; Vasoconstriction | 2004 |
Impaired modulation of sympathetic alpha-adrenergic vasoconstriction in contracting forearm muscle of ageing men.
Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Aged; Aging; Clonidine; Forearm; Hand Strength; Humans; Male; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Sympatholytics; Tyramine; Vasoconstriction | 2005 |
Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome.
Topics: Adenosine; Adult; Analgesics; Chronic Pain; Clonidine; Complex Regional Pain Syndromes; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Injections, Spinal; Male; Middle Aged; Pain Measurement; Treatment Outcome | 2015 |
70 other study(ies) available for clonidine and adenosine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neurotransmitter-sensitive adenylate cyclase in the hypothalami of guinea-pig, rat and monkey.
Topics: Adenosine; Adenylyl Cyclases; Animals; Apomorphine; Clonidine; Dopamine; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guinea Pigs; Haplorhini; Hypothalamus; Isoproterenol; Macaca mulatta; Male; Median Eminence; Neurotransmitter Agents; Norepinephrine; Piribedil; Rats; Serotonin; Sodium Fluoride | 1977 |
Clonidine as an adenosine antagonist.
Topics: Adenosine; Animals; Clonidine; In Vitro Techniques; Motor Neurons; Rats; Serotonin; Time Factors | 1978 |
CYCLIC AMP/*SECRETl cyclic AMP into push-pull perfusates in freely moving rats.
Topics: Adenosine; Animals; Brain; Cerebral Ventricles; Clonidine; Cyclic AMP; Dopamine; Histamine; Isoproterenol; Levodopa; Male; Norepinephrine; Perfusion; Rats; Receptors, Adrenergic; Serotonin | 1976 |
Cyclic adenosine 3',5'-monophosphate in rat cerebral cortical slices: effects of methoxamine and clonidine.
Topics: Adenosine; Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Isoproterenol; Male; Methoxamine; Norepinephrine; Phentolamine; Propranolol; Rats | 1979 |
Catecholaminergic alpha-receptors and shivering in the rat.
Topics: Adenosine; Animals; Blood Pressure; Clonidine; Injections, Intraventricular; Male; Methoxamine; Neural Pathways; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Shivering | 1979 |
Prejunctional clonidine-adenosine interactions in the rat vas deferens [proceedings].
Topics: Adenosine; Animals; Clonidine; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Rats; Vas Deferens | 1979 |
Is clonidine an adenosine antagonist?
Topics: Adenosine; Adenosine Monophosphate; Anesthesia, General; Animals; Clonidine; Depression, Chemical; Drug Synergism; Male; Methoxyflurane; Nitrous Oxide; Rats; Somatosensory Cortex; Urethane | 1979 |
Antagonism by clonidine of neuronal depressant responses to adenosine, adenosine-5'-monophosphate and adenosine triphosphate.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Clonidine; Male; Neurons; Rats; Time Factors | 1978 |
Effect of adenosine analogues on the expression of opiate withdrawal in rats.
Topics: Adenosine; Animals; Behavior, Animal; Clonidine; Diarrhea; Female; Male; Morphine Dependence; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Regional differences in triglyceride breakdown in human adipose tissue: effects of catecholamines, insulin, and prostaglandin E2.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Buttocks; Clonidine; Dinoprostone; Epinephrine; Female; Humans; Insulin; Lipolysis; Male; Sex Characteristics; Triglycerides; Yohimbine | 1991 |
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines | 1990 |
The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats.
Topics: Adenosine; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Captopril; Carrageenan; Clonidine; Leukocyte Count; Minoxidil; Neutrophils; Pleurisy; Rats; Receptors, Purinergic; Superoxides; Theophylline | 1990 |
Lipolytic effects on diacylglycerol accumulation in human adipose tissue in vitro.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adult; Clonidine; Diglycerides; Epinephrine; Female; Humans; Insulin; Lipolysis; Male; Middle Aged | 1990 |
Changes in plasma catecholamine levels after the intraperitoneal and intracerebroventricular administration of adenosine analogues and of clonidine in conscious rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Clonidine; Epinephrine; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Injections, Intraventricular; Male; Norepinephrine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1990 |
Antinociceptive interactions between intrathecally administered alpha noradrenergic agonists and 5'-N-ethylcarboxamide adenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Injections, Spinal; Male; Norepinephrine; Pain; Phenylephrine; Rats; Rats, Inbred Strains; Spinal Cord; Vasodilator Agents | 1990 |
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1986 |
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil; Motor Activity; Muscle Relaxants, Central; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, GABA-A; Receptors, Purinergic; Social Behavior | 1989 |
Alpha 2-adrenoceptor stimulation can augment coronary vasodilation maximally induced by adenosine in dogs.
Topics: Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Dogs; Oxygen Consumption; Propranolol; Receptors, Adrenergic, alpha; Receptors, Purinergic; Vasodilation | 1989 |
Beneficial effects of alpha 2-adrenoceptor activity on ischemic myocardium during coronary hypoperfusion in dogs.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Disease; Cyclic AMP; Dogs; Hemodynamics; Lactates; Myocardial Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Propranolol; Receptors, Adrenergic, alpha; Theophylline; Vasodilation; Yohimbine | 1989 |
Inositol phospholipid hydrolysis and potentiation of cyclic AMP formation by noradrenaline in rat cerebral cortex slices are not mediated by the same alpha-adrenoceptor subtypes.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Hydrolysis; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sugar Phosphates; Theophylline; Yohimbine | 1989 |
Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice.
Topics: Adenosine; Adrenergic alpha-Antagonists; Aminophylline; Animals; Anticonvulsants; Clonidine; Habituation, Psychophysiologic; Methysergide; Mice; Mice, Inbred DBA; Piperoxan; Yohimbine | 1989 |
Alpha 2-adrenergic, kappa-opiate, and P1-purinergic autoreceptors have mutually antagonistic effects: a new regulatory mechanism?
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Caffeine; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Fluorescent Dyes; Fura-2; Homeostasis; Idazoxan; Male; Naloxone; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Purinergic; Synaptosomes | 1989 |
Alinidine antagonizes the myocardial effects of adenosine.
Topics: Action Potentials; Adenosine; Animals; Atropine; Cardiovascular Agents; Clonidine; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Rats | 1989 |
Alpha 2-adrenoceptor activity exerts dual control of coronary blood flow in canine coronary artery.
Topics: Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Vessels; Dogs; Norepinephrine; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Vasodilation; Yohimbine | 1988 |
Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.
Topics: Adenosine; Aggression; Animals; Behavior, Animal; Caffeine; Carbamazepine; Clonidine; Haloperidol; Male; Mice; Prazosin; Receptors, Cell Surface; Yohimbine | 1988 |
Antagonism by clonidine of the adenosine-induced inhibition of the twitch contraction of the guinea-pig Oddi sphincter.
Topics: Adenosine; Alprostadil; Ampulla of Vater; Animals; Clonidine; Dipyridamole; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Prostaglandins E; Reserpine; Sphincter of Oddi; Theophylline; Yohimbine | 1985 |
Adrenergic regulation of lipolysis in abdominal adipocytes of obese subjects during caloric restriction: reversal of catecholamine action caused by relief of endogenous inhibition.
Topics: Adenosine; Adipose Tissue; Adolescent; Adrenergic Agonists; Adult; Aged; Catecholamines; Cells, Cultured; Clonidine; Energy Intake; Female; Glycerol; Humans; Isoproterenol; Lipolysis; Male; Middle Aged; Obesity; Starvation | 1985 |
The regulation of noradrenaline synthesis in central nerve terminals by autoreceptors and heteroreceptors in rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Synaptosomes; Tyrosine 3-Monooxygenase | 1985 |
Morphine tolerance and nonspecific subsensitivity of the longitudinal muscle myenteric plexus preparation of the guinea-pig to inhibitory agonists.
Topics: 2-Chloroadenosine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Guinea Pigs; Ileum; Male; Morphine; Muscle, Smooth; Myenteric Plexus; Xylazine | 1988 |
The effect of presynaptic receptor stimulation on adenosine 3',5'-cyclic monophosphate concentrations in rat cortical synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Baclofen; Cerebral Cortex; Clonidine; Cyclic AMP; gamma-Aminobutyric Acid; Male; Norepinephrine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synaptosomes | 1986 |
Alpha 2-adrenergic potentiation of adenosine-stimulating effect on glucagon secretion.
Topics: Adenosine; Animals; Clonidine; Drug Synergism; Epinephrine; Glucagon; Male; Pancreas; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Myenteric Plexus; Receptors, Cholinergic; Receptors, Neurotransmitter; Theophylline | 1987 |
Influences of variation in total energy intake and dietary composition on regulation of fat cell lipolysis in ideal-weight subjects.
Topics: Adenosine; Adipose Tissue; Body Weight; Catecholamines; Clonidine; Diet; Dinoprostone; Energy Metabolism; Fatty Acids, Nonesterified; Glycerol; Humans; Insulin; Lipid Mobilization; Lipids; Male; Prostaglandins E; Receptors, Purinergic | 1987 |
Interdependence of spinal adenosinergic, serotonergic and noradrenergic systems mediating antinociception.
Topics: Adenosine; Animals; Clonidine; Male; Methysergide; Mice; Nociceptors; Norepinephrine; Phentolamine; Reaction Time; Serotonin; Spinal Cord; Theophylline | 1987 |
Behavioral and cardiovascular effects of analogs of adenosine in cynomolgus monkeys.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Blood Pressure; Caffeine; Cardiovascular System; Clonidine; Cocaine; Dextroamphetamine; Heart Rate; Isomerism; Macaca fascicularis; Male; Phenylisopropyladenosine | 1987 |
Isolation of a factor that reverses presynaptic inhibition of acetylcholine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain; Brain Chemistry; Clonidine; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Morphine; Myenteric Plexus; Neuromuscular Junction; Oxotremorine; Phenylisopropyladenosine; Synapses; Synaptosomes | 1986 |
Blocking effects of alinidine on negative chronotropic and inotropic responses to vagal stimulation and injected acetylcholine and carbachol in dogs.
Topics: Acetylcholine; Adenosine; Animals; Atropine; Carbachol; Cardiovascular Agents; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Heart Rate; Myocardial Contraction; Vagus Nerve | 1987 |
Isolation of a factor (substance B) that antagonizes presynaptic modulation: pharmacological properties.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain Chemistry; Clonidine; Guinea Pigs; Hexamethonium Compounds; Ileum; Morphine; Muscle Contraction; Oxotremorine; Phencyclidine; Phenylisopropyladenosine; Synaptosomes | 1986 |
Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice.
Topics: Adenosine; Aggression; Animals; Apomorphine; Bicuculline; Clonidine; Diazepam; Dipyridamole; Humans; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Modulation of alpha 2-adrenergic receptors of rat vas deferens by adenosine receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding Sites; Clonidine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Purinergic; Vas Deferens; Yohimbine | 1984 |
Phosphatidic acid and phosphatidylinositol labelling in adipose tissue. The role of endogenously formed adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Clonidine; Cricetinae; In Vitro Techniques; Isoproterenol; Mesocricetus; Methoxamine; Phosphatidylinositols; Phospholipids | 1983 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Inhibition of lipolysis and cyclic AMP accumulation by adenosine analogues in hamster epididymal adipocytes exposed to cholera toxin.
Topics: Adenosine; Adipose Tissue; Animals; Cholera Toxin; Clonidine; Cricetinae; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epididymis; Lipolysis; Male; Phenylisopropyladenosine | 1980 |
Alpha 2 adrenergic amines, adenosine and prostaglandins inhibit lipolysis and cyclic AMP accumulation in hamster adipocytes in the absence of extracellular sodium.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Clonidine; Cricetinae; Cyclic AMP; Lipolysis; Mesocricetus; Phenylisopropyladenosine; Prostaglandins E; Sodium; Theophylline | 1981 |
Influence of development and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic responses.
Topics: Adenosine; Adipose Tissue; Animals; Clonidine; Cricetinae; Imidazoline Receptors; Isoproterenol; Kinetics; Lipolysis; Male; Mesocricetus; Phenylisopropyladenosine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Theophylline | 1983 |
Interaction between 2-chloroadenosine and alpha-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1984 |
The effects of phospholipase and 2-chloroadenosine treatments on alpha 2-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; In Vitro Techniques; Male; Phospholipases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1984 |
P-1 purinoceptor antagonism by clonidine in the rat caecum.
Topics: Adenosine; Animals; Cecum; Clonidine; Dose-Response Relationship, Drug; Female; Guanfacine; Guanidines; In Vitro Techniques; Male; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Development of clonidine-tolerance in the rat vas deferens: cross tolerance to other presynaptic inhibitory agents.
Topics: Adenosine; Animals; Azepines; Clonidine; Drug Tolerance; Endorphins; Evoked Potentials; Male; Methoxamine; Muscle Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Sympathomimetics; Vas Deferens | 1982 |
Facilitation by clonidine of purine release induced by high KCl from the rabbit pulmonary artery.
Topics: Adenosine; Animals; Clonidine; Denervation; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Potassium Chloride; Pulmonary Artery; Purines; Rabbits; Tritium | 1981 |
Histamine H3-receptor-induced inhibition of duodenal cholinergic transmission is independent of intracellular cyclic AMP and GMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Clonidine; Colforsin; Cyclic AMP; Cyclic GMP; Duodenum; Guinea Pigs; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine H3; Signal Transduction; Synaptic Transmission | 1993 |
The effects of adenosine A3 receptor stimulation on seizures in mice.
Topics: Adenosine; Animals; Clonidine; Drug Interactions; Electroshock; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; p-Methoxy-N-methylphenethylamine; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Seizures | 1995 |
In vitro studies of release of adenine nucleotides and adenosine from rat vascular endothelium in response to alpha 1-adrenoceptor stimulation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-1 Receptor Agonists; Animals; Aorta, Thoracic; Arteries; Cells, Cultured; Clonidine; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Wistar; Tail | 1994 |
Acute metabolic effects of clonidine and adenosine in man.
Topics: Adenosine; Adult; Aged; Blood Glucose; Blood Pressure; Clonidine; Fatty Acids, Nonesterified; Female; Heart Rate; Humans; Injections, Intravenous; Insulin; Male; Middle Aged; Respiration; Triglycerides | 1993 |
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine | 1997 |
Effects of drugs acting on adrenergic and adenosine receptors on the intraocular pressure and the activity of adenylyl cyclase in ciliary processes and their sensitivity to pertussis toxin.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Ciliary Body; Clonidine; Epinephrine; Fenoterol; Intraocular Pressure; Pertussis Toxin; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Adrenergic; Receptors, Purinergic P1; Virulence Factors, Bordetella; Yohimbine | 1997 |
Intrathecal adenosine: interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative hypersensitivity.
Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Male; Neostigmine; Pain, Postoperative; Rats; Rats, Sprague-Dawley | 1999 |
Modulation of norepinephrine release by ATP-dependent K(+)-channel activators and inhibitors in guinea-pig and human isolated right atrium.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Analysis of Variance; Animals; Clonidine; Cromakalim; Decanoic Acids; Diazoxide; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Heart Atria; Humans; Hydroxy Acids; In Vitro Techniques; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Pinacidil; Potassium Channel Blockers; Potassium Channels; Stimulation, Chemical; Sympathetic Nervous System | 1999 |
Systemic adenosine increase during cold pressor test is dependent on sympathetic activation.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clonidine; Cold Temperature; Female; Heart Rate; Humans; Male; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Sympathetic Nervous System; Theophylline; Vasoconstriction; Vasodilator Agents | 1999 |
Contemporary activation of different endothelial receptors accounts for a reserve mechanism of nitric oxide-mediated relaxation.
Topics: Acetylcholine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Endothelium, Vascular; Histamine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Histamine; Receptors, Muscarinic; Receptors, Purinergic; Vasodilator Agents | 2000 |
Characterization of prejunctional purinoceptors inhibiting noradrenaline release in rat mesenteric arteries.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Tetrodotoxin; Xanthines | 2001 |
Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.
Topics: Adenosine; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Clonidine; Female; GABA Agonists; Injections, Spinal; Ischemia; Morphine; Neuralgia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spinal Cord | 2001 |
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration | 2007 |
Unmasking the tonic-aversive state in neuropathic pain.
Topics: Adenosine; Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Clonidine; Conditioning, Classical; Conditioning, Psychological; Disease Models, Animal; Drug Administration Schedule; Hyperalgesia; Injections, Spinal; Male; Neuralgia; omega-Conotoxins; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Time Factors | 2009 |
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward | 2011 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine | 2013 |
The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anticonvulsants; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Pentylenetetrazole; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Seizures; Theophylline; Yohimbine | 2014 |