Compounds > clonidine

clonidine and 1-methyl-4-phenylpyridinium

clonidine has been researched along with 1-methyl-4-phenylpyridinium in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dresser, MJ; Giacomini, KM; Gray, AT; Terashita, S; Yost, SC; Zhang, L1
Giacomini, KM; Schaner, ME; Zhang, L1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Conway, SJ; Ganapathy, ME; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wu, X1
Bednarczyk, D; Ekins, S; Wikel, JH; Wright, SH1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Alessandrì, MG; Corsini, GU; Fascetti, F; Fornai, F; Vaglini, F1
Cavalletti, M; Corsini, GU; Fascetti, F; Fornai, F; Tedeschi, D; Vaglini, F1
Gliese, M; Gründemann, D; Martel, F; Russ, H; Schömig, E; Staudt, K1
Calhau, C; Gründemann, D; Martel, F; Schömig, E1
Bridges, CC; Friedrich, A; Ganapathy, V; George, RL; Prasad, PD1

Other Studies

12 other study(ies) available for clonidine and 1-methyl-4-phenylpyridinium

ArticleYear
Cloning and functional expression of a human liver organic cation transporter.
    Molecular pharmacology, 1997, Volume: 51, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Tissue Distribution; Xenopus laevis

1997
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection

1998
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Binding, Competitive; Carbon Radioisotopes; Cations; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Dopamine Agents; Exons; Gene Expression Regulation; HeLa Cells; Herbicides; Humans; In Situ Hybridization; Introns; Kidney; Mice; Niacinamide; Octamer Transcription Factor-3; Oocytes; Pigment Epithelium of Eye; RNA, Messenger; Tetraethylammonium; Transcription Factors; Tritium; Xenopus laevis

2000
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.
    Molecular pharmacology, 2003, Volume: 63, Issue:3

    Topics: Computational Biology; HeLa Cells; Humans; Models, Molecular; Organic Cation Transporter 1; Pyridinium Compounds; Quinolinium Compounds; Structure-Activity Relationship; Transfection

2003
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Clonidine suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced reductions of striatal dopamine and tyrosine hydroxylase activity in mice.
    Journal of neurochemistry, 1995, Volume: 65, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenergic alpha-Agonists; Animals; Clonidine; Corpus Striatum; Dopamine Antagonists; Imidazoles; Male; Mice; Mice, Inbred C57BL; Tyrosine 3-Monooxygenase; Yohimbine

1995
Striatal MPP+ levels do not necessarily correlate with striatal dopamine levels after MPTP treatment in mice.
    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetaldehyde; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Ditiocarb; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nicotine; Piperazines; Selegiline; Serotonin

1996
The extraneuronal monoamine transporter exists in human central nervous system glia.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Glioma; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Neuroglia; Neuropeptides; Neurotransmitter Agents; Quinolinium Compounds; Rats; Tumor Cells, Cultured; Vesicular Biogenic Amine Transport Proteins

1998
Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Caco-2 Cells; Carrier Proteins; Cations; Cell Line; Clonidine; Corticosterone; DNA, Recombinant; Dose-Response Relationship, Drug; Gene Expression; Histamine; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Membrane Potentials; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Plasmids; Quinolines; Quinolinium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Time Factors; Transfection; Tritium

2001
Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).
    Biochimica et biophysica acta, 2001, Jun-06, Volume: 1512, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Brain; Brain Stem; Carrier Proteins; Cell Line; Cerebrovascular Circulation; Choline; Clonidine; Endothelium, Vascular; Hemicholinium 3; Kidney; Kinetics; Membrane Proteins; Microcirculation; Organic Cation Transporter 1; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Transcription, Genetic

2001