clonazepam and flunitrazepam

clonazepam has been researched along with flunitrazepam in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	46 (50.55)	18.7374
1990's	26 (28.57)	18.2507
2000's	8 (8.79)	29.6817
2010's	11 (12.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blair, T; Webb, GA	1
Aoyama, T; Ichikawa, H; Suzuki, Y	1
Anderson, PS; Bock, MG; Chang, RS; DiPardo, RM; Evans, BE; Freidinger, RM; Lundell, GF; Rittle, KE; Veber, DF; Whitter, WL	1
Bock, MG; DiPardo, RM; Evans, BE; Freidinger, RM; Gould, NP; Homnick, CF; Lundell, GF; Rittle, KE; Veber, DF; Whitter, WL	1
Johnston, GA; Maddalena, DJ	1
Karplus, M; So, SS	1
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Aubert, C; Cano, JP; Guintrand, J; Viala, A	1
Bird, ED; Reisine, TD; Speth, RC; Wastek, GJ; Yamamura, HI	1
Baraldi, M; Costa, E; Guidotti, A; Schwartz, JP	1
Bekersky, I; Brooks, MA; de Silva, JA; Puglisi, CV; Weinfeld, RE	1
Furuie, MA; Hibino, S; Maruyama, T; Otagiri, M	1
Fiszer de Plazas, S; Gravielle, MC	1
Constantidinis, J; Javoy-Agid, F; Lloyd, GK; Lowenthal, A	1
Barnes, EM; Tehrani, MH	2
Bondoux, D; Chapouthier, G; Desforges, C; Launay, JM; Martin, B	1
Scarth, BA; Shaw, C	1
Machen, VL; Swaiman, KF	2
Breimer, DD; de Boer, AG; van Hoogdalem, E	1
De Luca, C; De Medici, D; Massotti, M	1
Ge, LJ; Kastin, AJ; Zadina, JE	1
Wong, PT	1
Faull, RL; Villiger, JW	1
Kubo, H; Miura, H; Nishida, A; Nishikawa, T; Ohtani, H; Sudo, Y; Sunaoshi, W	1
Black, KL; Ikezaki, K; Toga, AW	1
Sieghart, W	2
Ciliax, BJ; Mancini, WR; Olson, JM; Young, AB	1
Clow, A; Glover, V; Sandler, M	1
Boespflug, O; Swaiman, KF	1
Massotti, M; Valerio, A	1
Concas, A; Morelli, M; Obata, T; Serra, M; Yamamura, HI	1
Haumont, J; Lenfant, M; Potier, P; Zavala, F	1
Goeders, NE; Kuhar, MJ	1
Bobillier, P; Kopp, N; Manchon, M; Miachon, S	1
Haefely, W; Möhler, H; Richards, JG; Schoch, P	1
Machen, VL; Neale, EA; Sher, PK	1
Ciliax, BJ; Penney, JB; Young, AB	1
Hrelia, S; Lucacchini, A; Martini, C; Rossi, CA	1
Cecchi, L; Filacchioni, G; Lucacchini, A; Martini, C; Melani, F; Palazzino, G; Pennacchi, E	1
Lafaille, F; Lal, S; Nair, NP; Quirion, R; Suranyi-Cadotte, B	1
Machen, VL; Sher, PK	1
Marano, F; Miernik, A; Santa-Maria, A	1
Dorie, LD; Haver, VM; Lea, JR; Porter, WH	1
Herblin, WF; Mechem, CC	1
Bender, AS; Hertz, L	1
Beaumont, K; Fanestil, DD; Healy, DP	1
Fioretti, P; Galbani, P; Gambacciani, M; Melis, G; Ronca-Testoni, S	1
Anderson, RA; Mitchell, R	1
Caputti, E; Cardinali, DP; Lowenstein, PR; Rosenstein, R	1
Janicki, P; Szreniawski, Z	1
Moehler, H; Sieghart, W	1
Georgiev, VP; Getova, D; Petkov, V; Petkov, VV	1
Bylund, DB; Feller, DJ; Schroeder, F	1
Kuhar, MJ; Palacios, JM	1
Fehske, KJ; Muller, WE	1
Sher, PK	1
DeLorenzo, RJ; Taft, WC	1
de Bruyne, MM; Sinnema, A; Verweij, AM	1
Rovei, V; Sanjuan, M	1
Niles, LP; Tenn, CC	1
Drummer, OH; Robertson, MD	2
Fuchs, K; Mossier, B; Sieghart, W; Tögel, M	1
Harris, RA; Klein, RL; Whiting, PJ	1
Edge, J; Mimaki, T; Suzuki, Y; Walson, PD; Wang, L	1
Barton, JM; Olson, MS; Svetlov, SI	1
Middleton, R; Sparks, C; Valentine, JL	1
Bessler, H; Caspi, B; Gavish, M; Rehavi, M; Weizman, A	1
Bechgaard, E; Gizurarson, S; Greenough, RJ; Hjortkjaer, RK; McDonald, P; Suzdak, C	1
Bono, F; Herbert, JM; Lamarche, I; Le Fur, G; Prabonnaud, V	1
El Mahjoub, A; Staub, C	1
Li, M; Rosenberg, HC; Szabo, A	1
Dowd, SM; Janicak, PG; Negrusz, A; Strong, MJ	1
Lopes, DV; Mendonça-Silva, DL; Noël, F; Thibaut, JP	1
Burin, E; Dally, S; Djezzar, S; Questel, F	1
Dervaux, A; Kanit, M; Laqueille, X; Launay, C	1
Gunn, J; Kriger, S; Terrell, AR	1
Chèze, M; Deveaux, M; Hoizey, G; Muckensturm, A; Pépin, G	1
Arditti, J; Frauger, E; Lapeyre Mestre, M; Micallef, J; Pauly, V; Pradel, V; Rouby, F; Thirion, X	1
Frauger, E; Lapeyre-Mestre, M; Micallef, J; Natali, F; Nordmann, S; Pauly, V; Pourcel, L; Pradel, V; Sciortino, V; Thirion, X	1
Haenisch, B; Huber, M; Molderings, GJ; Steffens, M; Wilhelm, T	1
Dulaurent, S; Gaulier, JM; Lachâtre, G; Maublanc, J; Morichon, J	1
Cui, YL; He, X; Liu, J; Shan, WC; Wang, JP; Zhang, L	1
Gjerde, H; Høiseth, G; Middelkoop, G; Mørland, J	1
Gjerde, H; Koksæter, P; Strand, DH; Vindenes, V	1
Holm, KM; Linnet, K; Skov, L	1

Reviews

4 review(s) available for clonazepam and flunitrazepam

Article	Year
Neural networks applied to quantitative structure-activity relationship analysis. Journal of medicinal chemistry, 1990, Volume: 33, Issue:9 Topics: Animals; Azirines; Benzodiazepines; Carbazilquinone; Nerve Net; Nervous System; Regression Analysis; Structure-Activity Relationship	1990
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid	1991
Benzodiazepine receptors resolved. Experientia, 1986, Feb-15, Volume: 42, Issue:2 Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution	1986
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature]. L'Encephale, 2009, Volume: 35, Issue:3 Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium; Comorbidity; Controlled Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; Euphoria; Flunitrazepam; Heroin Dependence; Humans; Metabolic Clearance Rate; Methadone; Narcotics; Substance-Related Disorders; Young Adult	2009

Other Studies

87 other study(ies) available for clonazepam and flunitrazepam

Article	Year
Electronic factors in the structure-activity relationship of some 1,4-benzodiazepin-2-ones. Journal of medicinal chemistry, 1977, Volume: 20, Issue:9 Topics: Benzodiazepinones; Electrochemistry; Structure-Activity Relationship	1977
Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:12 Topics: Administration, Oral; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Cholecystokinin; Drug Design; Mice; Receptors, Cholecystokinin; Receptors, GABA-A; Structure-Activity Relationship	1988
Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists. Journal of medicinal chemistry, 1987, Volume: 30, Issue:7 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cholecystokinin; Guinea Pigs; Ligands; Rats; Receptors, Cholecystokinin; Receptors, GABA-A; Structure-Activity Relationship	1987
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks. Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4 Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship	1995
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors. Journal of medicinal chemistry, 1996, Dec-20, Volume: 39, Issue:26 Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Determination of flunitrazepam, desmethylflunitrazepam and clonazepam in plasma by gas liquid chromatography with an internal standard. Arzneimittel-Forschung, 1977, Volume: 27, Issue:2 Topics: Administration, Oral; Anti-Anxiety Agents; Benzodiazepinones; Biotransformation; Child; Chromatography, Gas; Clonazepam; Dealkylation; Flunitrazepam; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Methods	1977
Alterations in the benzodiazepine receptor of Huntington's diseased human brain. Brain research, 1979, Apr-06, Volume: 165, Issue:1 Topics: Aged; Anti-Anxiety Agents; Brain; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Frontal Lobe; Humans; Huntington Disease; Middle Aged; Putamen; Receptors, Drug	1979
GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level. Science (New York, N.Y.), 1979, Aug-24, Volume: 205, Issue:4408 Topics: Animals; Benzodiazepines; Brain; Cell Line; Clonazepam; Clone Cells; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Mice; Nerve Tissue Proteins; Rats; Receptors, Drug	1979
Determination of 1,4-benzodiazepines and -diazepin-2-ones in blood by electron-capture gas-liquid chromatography. Analytical chemistry, 1976, Volume: 48, Issue:1 Topics: Benzodiazepines; Benzodiazepinones; Bromazepam; Chromatography, Gas; Clonazepam; Diazepam; Flunitrazepam; Humans	1976
Comparative study of interaction mode of diazepines with human serum albumin and alpha 1-acid glycoprotein. Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:1 Topics: Anti-Anxiety Agents; Bromazepam; Clonazepam; Diazepam; Flunitrazepam; Humans; Orosomucoid; Oxazepam; Protein Binding; Regression Analysis; Serum Albumin; Spectrometry, Fluorescence	1992
Benzodiazepine receptor sites in the chick optic lobe: development and pharmacological characterization. Neurochemical research, 1991, Volume: 16, Issue:1 Topics: Animals; Binding, Competitive; Chick Embryo; Chickens; Clonazepam; Flumazenil; Flunitrazepam; Kinetics; Receptors, GABA-A; Synaptic Membranes; Tectum Mesencephali; Time Factors	1991
GABAA receptor complex function in frontal cortex membranes from control and neurological patients. European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1 Topics: Adult; Aged; Alzheimer Disease; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonazepam; Female; Flunitrazepam; Humans; Huntington Disease; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Middle Aged; Nervous System Diseases; Parkinson Disease; Pyridines; Receptors, GABA-A	1991
Agonist-dependent internalization of gamma-aminobutyric acidA/benzodiazepine receptors in chick cortical neurons. Journal of neurochemistry, 1991, Volume: 57, Issue:4 Topics: Animals; Benzodiazepines; Cerebral Cortex; Chick Embryo; Clonazepam; Flunitrazepam; gamma-Aminobutyric Acid; Neurons; Osmolar Concentration; Receptors, GABA-A; Regression Analysis	1991
Genetic difference in sensitivity to beta-carboline: evidence for the involvement of brain benzodiazepine receptors. Brain research, 1991, Jul-12, Volume: 553, Issue:2 Topics: Animals; Brain; Carbolines; Clonazepam; Convulsants; Flunitrazepam; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, GABA-A; Seizures; Species Specificity; Strychnine	1991
Characterization and differential regulation of GABAA and benzodiazepine receptors in rat neocortex. Brain research. Molecular brain research, 1991, Volume: 11, Issue:3-4 Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Clonazepam; Down-Regulation; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium; Veratridine	1991
Effect of ferric nitrilotriacetate on rostral mesencephalic cells. Neurochemical research, 1991, Volume: 16, Issue:12 Topics: Animals; Cells, Cultured; Clonazepam; Dopamine; Ferric Compounds; Flunitrazepam; Glutamate-Ammonia Ligase; Haloperidol; Mesencephalon; Mice; Neuroglia; Neurons; Nitrilotriacetic Acid; Spiperone	1991
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem	1990
Tyr-MIF-1 binding in brain is not altered by ligands selective for the GABAA/benzodiazepine receptor. Neuroscience letters, 1990, Mar-02, Volume: 110, Issue:1-2 Topics: Animals; Brain; Clonazepam; Flunitrazepam; gamma-Aminobutyric Acid; Male; MSH Release-Inhibiting Hormone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter	1990
Characterization by saturation studies of the in vivo binding of [3H]flunitrazepam in mouse brain. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:2 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Flunitrazepam; Kinetics; Mice; Nordazepam; Oxazepam	1991
Benzodiazepine receptors in the human spinal cord: a detailed anatomical and pharmacological study. Neuroscience, 1986, Volume: 17, Issue:3 Topics: Adult; Autoradiography; Clonazepam; Female; Flunitrazepam; Humans; Male; Mathematics; Neurons; Receptors, GABA-A; Spinal Cord; Substance P	1986
Radioreceptor assay of clonazepam and diazepam in blood for therapeutic drug monitoring. Therapeutic drug monitoring, 1989, Volume: 11, Issue:4 Topics: Adolescent; Animals; Child; Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Flunitrazepam; Humans; Male; Nordazepam; Radioligand Assay; Rats	1989
Imaging of brain tumors using peripheral benzodiazepine receptor ligands. Journal of neurosurgery, 1989, Volume: 71, Issue:1 Topics: Animals; Autoradiography; Brain Neoplasms; Clonazepam; Female; Flunitrazepam; Glioma; Image Processing, Computer-Assisted; Isoquinolines; Ligands; Rats; Rats, Inbred Strains; Receptors, GABA-A	1989
Effect of ferric nitrilotriacetate on predominantly cortical neuronal cell cultures. Neurochemical research, 1989, Volume: 14, Issue:7 Topics: Acetates; Animals; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Choline O-Acetyltransferase; Clonazepam; Ferric Compounds; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Neurons; Nitrilotriacetic Acid; Proteins	1989
Comparison of two different benzodiazepine binding proteins by peptide mapping after limited proteolysis. Brain research, 1988, May-31, Volume: 450, Issue:1-2 Topics: Animals; Azides; Benzodiazepines; Binding Sites; Brain Chemistry; Cerebellum; Clonazepam; Flunitrazepam; Hippocampus; Molecular Weight; Peptide Mapping; Rats; Receptors, GABA-A	1988
Presence of peripheral-type benzodiazepine binding sites on human erythrocyte membranes. European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2 Topics: Benzodiazepinones; Clonazepam; Convulsants; Erythrocyte Membrane; Flunitrazepam; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Monoamine Oxidase; Receptors, GABA-A	1988
Triazolam, an anomalous benzodiazepine receptor ligand: in vitro characterization of alprazolam and triazolam binding. Journal of neurochemistry, 1985, Volume: 45, Issue:2 Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Clonazepam; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Triazolam	1985
Neurotransmitter changes during development of cortical neuronal cultures. Developmental neuroscience, 1986, Volume: 8, Issue:2 Topics: Animals; Benzodiazepinones; Cells, Cultured; Cerebral Cortex; Choline O-Acetyltransferase; Clonazepam; Diazepam; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Neurotransmitter Agents	1986
Electroencephalographic changes after short-term exposure to agonists of benzodiazepine receptors in the rat. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4 Topics: Animals; Anti-Anxiety Agents; Brain; Clonazepam; Electroencephalography; Flunitrazepam; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A	1988
Modulation of GABA-stimulated chloride influx into membrane vesicles from rat cerebral cortex by benzodiazepines and nonbenzodiazepines. Advances in biochemical psychopharmacology, 1988, Volume: 45 Topics: Animals; Anti-Anxiety Agents; Cell Membrane; Cerebral Cortex; Chlorides; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains	1988
[Presence of a peripheral type benzodiazepine binding site on the macrophage; its possible role in immunomodulation]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1985, Volume: 300, Issue:8 Topics: Animals; Antibody Formation; Benzodiazepines; Benzodiazepinones; Clonazepam; Erythrocytes; Ethanol; Female; Flunitrazepam; Macrophages; Mice; Receptors, GABA-A; Sheep	1985
Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788. Life sciences, 1985, Jul-29, Volume: 37, Issue:4 Topics: Animals; Autoradiography; Benzodiazepinones; Brain; Clonazepam; Flumazenil; Flunitrazepam; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Time Factors; Tritium	1985
Autoradiographic and quantitative study of benzodiazepine-binding sites in human hippocampus. Neuroscience letters, 1985, Nov-20, Volume: 62, Issue:1 Topics: Adolescent; Adult; Aged; Anxiety; Autoradiography; Benzodiazepines; Binding Sites; Binding, Competitive; Clonazepam; Female; Flunitrazepam; Hippocampus; Humans; Male; Middle Aged; Pyridazines; Receptors, GABA-A; Tritium	1985
Autoradiographic localization of benzodiazepine receptor binding in dissociated cultures of fetal mouse cerebral cortex. Journal of neurochemistry, 1986, Volume: 46, Issue:3 Topics: Affinity Labels; Animals; Autoradiography; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Clonazepam; Embryo, Mammalian; Flunitrazepam; Mice; Neurons; Photochemistry; Receptors, GABA-A	1986
Comparison of benzodiazepine receptors in cerebellum and inferior colliculus. Journal of neurochemistry, 1986, Volume: 47, Issue:3 Topics: Aging; Animals; Animals, Newborn; Carbolines; Cell Membrane; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Inferior Colliculi; Pyridazines; Rats; Receptors, GABA-A	1986
In vivo [3H]flunitrazepam binding: imaging of receptor regulation. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Animals; Autoradiography; Binding, Competitive; Brain; Clonazepam; Flunitrazepam; Kainic Acid; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors; Tritium	1986
Central- and peripheral-type benzodiazepine receptors. Advances in biochemical psychopharmacology, 1986, Volume: 41 Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Clonazepam; Convulsants; Flunitrazepam; Kidney; Kinetics; Membranes; Muscimol; Rats; Receptors, GABA-A; Subcellular Fractions; Tissue Distribution	1986
Pyrazolo[4,5-c]quinolines. 3. Synthesis, receptor binding, and 13C NMR study. Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:12 Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Cattle; Chemical Phenomena; Chemistry; Clonazepam; Flunitrazepam; In Vitro Techniques; Magnetic Resonance Spectroscopy; Pyrazoles; Quinolines; Receptors, GABA-A	1986
Coexistence of central and peripheral benzodiazepine binding sites in the human pineal gland. Life sciences, 1987, Apr-13, Volume: 40, Issue:15 Topics: Aged; Benzodiazepinones; Binding, Competitive; Cell Membrane; Clonazepam; Female; Flumazenil; Flunitrazepam; Humans; Isoquinolines; Male; Middle Aged; Pineal Gland; Receptors, GABA-A	1987
Benzodiazepine receptor affinity alterations at physiologic temperature after chronic clonazepam exposure. Brain & development, 1987, Volume: 9, Issue:1 Topics: Animals; Benzodiazepinones; Body Temperature; Cells, Cultured; Cerebral Cortex; Clonazepam; Convulsants; Flunitrazepam; Kinetics; Mice; Receptors, GABA-A; Time Factors	1987
The antimitotic activities of some benzodiazepines. Experientia, 1986, Aug-15, Volume: 42, Issue:8 Topics: Benzodiazepines; Chlorophyta; Chromosomes; Clonazepam; Diazepam; Flunitrazepam; Medazepam; Mitosis; Nitrazepam	1986
Simplified high performance liquid chromatographic method for the determination of clonazepam and other benzodiazepines in serum. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Benzodiazepines; Benzodiazepinones; Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; Humans	1986
Short-wave ultraviolet irradiation increases photo-affinity labeling of benzodiazepine sites. Life sciences, 1984, Jul-16, Volume: 35, Issue:3 Topics: Affinity Labels; Animals; Benzodiazepinones; Binding Sites; Cell Membrane; Cerebellum; Cerebral Cortex; Clonazepam; Flumazenil; Flunitrazepam; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Ultraviolet Rays	1984
Flunitrazepam binding to intact and homogenized astrocytes and neurons in primary cultures. Journal of neurochemistry, 1984, Volume: 43, Issue:5 Topics: Animals; Astrocytes; Benzodiazepinones; Cells, Cultured; Clonazepam; Diazepam; Flunitrazepam; Kinetics; Mice; Neurons; Receptors, GABA-A; Temperature	1984
Autoradiographic localization of benzodiazepine receptors in the rat kidney. The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 2 Topics: Animals; Autoradiography; Benzodiazepinones; Clonazepam; Diazepam; Flunitrazepam; Kidney; Kidney Tubules, Distal; Loop of Henle; Male; Mucoproteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium; Uromodulin	1984
Benzodiazepine binding sites in human myometrium. International journal of tissue reactions, 1984, Volume: 6, Issue:5 Topics: Adult; Benzodiazepinones; Binding Sites; Cell Membrane; Clonazepam; Diazepam; Female; Flunitrazepam; Humans; In Vitro Techniques; Lorazepam; Middle Aged; Myometrium; Receptors, GABA-A	1984
Analysis of benzodiazepine binding sites in rat pituitary gland. Brain research, 1984, Dec-10, Volume: 323, Issue:2 Topics: Animals; Benzodiazepinones; Binding, Competitive; Clonazepam; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, GABA-A	1984
Benzodiazepine binding sites in human pineal gland. European journal of pharmacology, 1984, Nov-13, Volume: 106, Issue:2 Topics: Adolescent; Adult; Aged; Animals; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Child; Child, Preschool; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Infant; Kinetics; Male; Middle Aged; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, GABA-A	1984
Effect of estazolam on the caudate spindle in the cat. Activitas nervosa superior, 1981, Volume: 23, Issue:2 Topics: Animals; Anti-Anxiety Agents; Cats; Caudate Nucleus; Clonazepam; Diazepam; Electroencephalography; Estazolam; Female; Flunitrazepam; Male	1981
[3H]clonazepam, like [3H]flunitrazepam, is a photoaffinity label for the central type of benzodiazepine receptors. European journal of pharmacology, 1982, Jun-16, Volume: 81, Issue:1 Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Clonazepam; Flunitrazepam; In Vitro Techniques; Rats; Receptors, Drug; Receptors, GABA-A; Ultraviolet Rays	1982
Effects of some benzodiazepines on the acetylcholine release in the anterior horn of the lateral cerebral ventricle of the cat. Acta physiologica et pharmacologica Bulgarica, 1982, Volume: 8, Issue:3 Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Benzodiazepinones; Cats; Cerebral Ventricles; Clonazepam; Diazepam; Flunitrazepam; Male	1982
Binding of [3H]flunitrazepam to the LM cell, a transformed murine fibroblast. Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding Sites; Cell Line; Cell Membrane; Choline; Clonazepam; Culture Media; Cyclic AMP; Flunitrazepam; Kinetics; Mice; Neoplasms, Experimental; Phospholipids	1983
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study. Brain research, 1981, Volume: 254, Issue:4 Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A	1981
beta-Carboline inhibition of benzodiazepine receptor binding in vivo. Brain research, 1982, Apr-22, Volume: 238, Issue:1 Topics: Animals; Binding, Competitive; Carbolines; Clonazepam; Diazepam; Flunitrazepam; Indoles; Male; Muridae; Receptors, Drug; Receptors, GABA-A	1982
Development and differentiation of the benzodiazepine receptor in cultures of fetal mouse spinal cord. Brain research, 1983, Volume: 283, Issue:2-3 Topics: Animals; Benzodiazepinones; Cell Differentiation; Clonazepam; Diazepam; Fetus; Flunitrazepam; Kinetics; Mice; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord	1983
Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive calcium channels in nerve terminal preparations. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:10 Topics: Animals; Benzodiazepines; Brain; Calcium; Cations, Divalent; Clonazepam; Diazepam; Female; Flunitrazepam; Ion Channels; Kinetics; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes	1984
Hydrolysis of clonazepam, flunitrazepam and nitrazepam by hydrochloric acid. Identification of some additional products. Forensic science international, 1984, Volume: 24, Issue:2 Topics: Benzodiazepines; Benzodiazepinones; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clonazepam; Flunitrazepam; Humans; Hydrolysis; Nitrazepam; Spectrum Analysis	1984
Simple and specific high performance liquid chromatographic method for the routine monitoring of clonazepam in plasma. Therapeutic drug monitoring, 1980, Volume: 2, Issue:3 Topics: Adult; Benzodiazepinones; Chromatography, High Pressure Liquid; Clonazepam; Epilepsy; Flunitrazepam; Humans; Infant, Newborn; Quality Control; Reference Standards	1980
Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1 Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Clonazepam; Corpus Striatum; Dopamine Agonists; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Isoquinolines; Male; Melatonin; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1995
High-performance liquid chromatographic procedure for the measurement of nitrobenzodiazepines and their 7-amino metabolites in blood. Journal of chromatography. B, Biomedical applications, 1995, May-05, Volume: 667, Issue:1 Topics: Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; Humans; Nitrazepam; Reproducibility of Results; Spectrophotometry, Ultraviolet	1995
Immunoaffinity purification of gamma-aminobutyric acidA (GABAA) receptors containing gamma 1-subunits. Evidence for the presence of a single type of gamma-subunit in GABAA receptors. The Journal of biological chemistry, 1994, Oct-14, Volume: 269, Issue:41 Topics: Animals; Antibody Specificity; Base Sequence; Blotting, Western; Brain Chemistry; Chromatography, Affinity; Clonazepam; Enzyme-Linked Immunosorbent Assay; Flumazenil; Flunitrazepam; Immunologic Techniques; Molecular Sequence Data; Molecular Weight; Muscimol; Peptide Fragments; Protein Conformation; Rats; Receptors, GABA-A; Recombinant Fusion Proteins	1994
Benzodiazepine treatment causes uncoupling of recombinant GABAA receptors expressed in stably transfected cells. Journal of neurochemistry, 1994, Volume: 63, Issue:6 Topics: Allosteric Site; Animals; Benzodiazepines; Cattle; Cell Line; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Receptors, GABA; Recombinant Proteins; Transfection	1994
Anticonvulsant tolerance to clonazepam in amygdala kindled rats: clonazepam concentrations and benzodiazepine receptor binding. Neuropharmacology, 1994, Volume: 33, Issue:7 Topics: Amygdala; Animals; Anticonvulsants; Clonazepam; Drug Tolerance; Electrophysiology; Flunitrazepam; Kindling, Neurologic; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1994
Identification of GABAA/benzodiazepine receptors on clathrin-coated vesicles from rat brain. Journal of neurochemistry, 1993, Volume: 60, Issue:5 Topics: Animals; Binding, Competitive; Brain; Clathrin; Clonazepam; Coated Pits, Cell-Membrane; Female; Flunitrazepam; Microscopy, Electron; Rats; Receptors, GABA-A; Subcellular Fractions	1993
The specific binding of the platelet-activating factor (PAF) receptor antagonist WEB 2086 and the benzodiazepine flunitrazepam to rat hepatocytes. Life sciences, 1996, Volume: 58, Issue:5 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Azepines; Benzodiazepinones; Bicuculline; Cells, Cultured; Clonazepam; Convulsants; Flunitrazepam; Kinetics; Liver; Male; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Tritium	1996
Identification of urinary benzodiazepines and their metabolites: comparison of automated HPLC and GC-MS after immunoassay screening of clinical specimens. Journal of analytical toxicology, 1996, Volume: 20, Issue:6 Topics: 1-Propanol; Acetamides; Anti-Anxiety Agents; Chloroform; Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrolysis; Inpatients; Reference Standards; Trimethylsilyl Compounds	1996
Significant inhibition of spontaneous IgA secretion by selective peripheral-type benzodiazepine receptor ligands. Clinical neuropharmacology, 1997, Volume: 20, Issue:3 Topics: Anti-Anxiety Agents; Antibody-Producing Cells; B-Lymphocytes; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Antagonists; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Isoquinolines; Lymphocyte Activation	1997
Postmortem distribution and redistribution of nitrobenzodiazepines in man. Journal of forensic sciences, 1998, Volume: 43, Issue:1 Topics: Autopsy; Bile; Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; GABA Modulators; Humans; Hypnotics and Sedatives; Liver; Nitrazepam; Postmortem Changes; Time Factors; Tissue Distribution; Vitreous Body	1998
Single- and repeated-dose local toxicity in the nasal cavity of rabbits after intranasal administration of different glycols for formulations containing benzodiazepines. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:4 Topics: Administration, Intranasal; Animals; Anti-Anxiety Agents; Benzodiazepines; Chemistry, Pharmaceutical; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Flunitrazepam; Lorazepam; Nasal Cavity; Pharmaceutic Aids; Polyethylene Glycols; Rabbits; Time Factors	1999
Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activities. Biochemical and biophysical research communications, 1999, Nov-19, Volume: 265, Issue:2 Topics: Apoptosis; Benzodiazepinones; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Isoquinolines; Jurkat Cells; Kinetics; Ligands; Receptors, GABA-A; Transfection; Tumor Necrosis Factor-alpha; U937 Cells	1999
Stability of benzodiazepines in whole blood samples stored at varying temperatures. Journal of pharmaceutical and biomedical analysis, 2000, Volume: 23, Issue:6 Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Clonazepam; Drug Stability; Flunitrazepam; Forensic Medicine; Humans; Midazolam; Oxazepam; Temperature; Time Factors	2000
Evaluation of native GABA(A) receptors containing an alpha 5 subunit. European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1 Topics: Alkynes; Animals; Anti-Anxiety Agents; Anticonvulsants; Autoradiography; Benzodiazepines; Cerebellum; Clobazam; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Imidazoles; Male; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	2001
The behavioral and cognitive effects of two benzodiazepines associated with drug-facilitated sexual assault. Journal of forensic sciences, 2002, Volume: 47, Issue:5 Topics: Adult; Anti-Anxiety Agents; Attention; Clonazepam; Female; Flunitrazepam; GABA Modulators; Humans; Male; Memory; Middle Aged; Rape; Substance Abuse Treatment Centers	2002
Characterization of two classes of benzodiazepine binding sites in Schistosoma mansoni. Parasitology, 2007, Volume: 134, Issue:Pt 7 Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Clonazepam; Diazepam; Flunitrazepam; GABA Agonists; GABA Modulators; Inhibitory Concentration 50; Isoquinolines; Ligands; Male; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Schistosoma mansoni; Synaptosomes; Temperature; Time Factors; Tritium; Zolpidem	2007
Chemical submission: results of 4-year French inquiry. International journal of legal medicine, 2009, Volume: 123, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzodiazepines; Bromazepam; Child; Child Abuse; Child, Preschool; Clonazepam; Crime; Data Collection; Female; Flunitrazepam; Homicide; Humans; Male; Middle Aged; Psychotropic Drugs; Pyridines; Rape; Sodium Oxybate; Theft; Young Adult; Zolpidem	2009
Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603 Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Chromatography, Liquid; Clonazepam; Flunitrazepam; Humans; Lorazepam; Midazolam; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry	2010
A tendency for re-offending in drug-facilitated crime. Forensic science international, 2010, Mar-20, Volume: 196, Issue:1-3 Topics: Adult; Anti-Anxiety Agents; Chromatography, Liquid; Clonazepam; Crime Victims; Doxylamine; Drug Combinations; Female; Flunitrazepam; Forensic Toxicology; Hair; Humans; Hypnotics and Sedatives; Limit of Detection; Lorazepam; Male; Mass Spectrometry; Middle Aged; Phenothiazines; Pyridines; Rape; Recurrence; Zolpidem	2010
Evidence of clonazepam abuse liability: results of the tools developed by the French Centers for Evaluation and Information on Pharmacodependence (CEIP) network. Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5 Topics: Behavior, Addictive; Benzodiazepines; Clonazepam; Data Collection; Databases, Factual; Drug Prescriptions; Epidemiologic Methods; Flunitrazepam; France; Fraud; Humans; Practice Patterns, Physicians'; Psychotropic Drugs; Substance Abuse Treatment Centers; Substance-Related Disorders	2011
Monitoring of benzodiazepine diversion using a multi-indicator approach. International clinical psychopharmacology, 2011, Volume: 26, Issue:5 Topics: Benzodiazepines; Clonazepam; Cross-Sectional Studies; Data Collection; Databases, Factual; Diazepam; Flunitrazepam; Humans; Prescription Drugs; Principal Component Analysis; Substance-Related Disorders	2011
Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling. Life sciences, 2013, Mar-14, Volume: 92, Issue:6-7 Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Female; Flunitrazepam; Gene Expression; Gene Expression Profiling; HL-60 Cells; Humans; Male; Mast Cells; Mastocytosis; Microarray Analysis; Middle Aged; Polymerase Chain Reaction	2013
Identification and quantification of 35 psychotropic drugs and metabolites in hair by LC-MS/MS: application in forensic toxicology. International journal of legal medicine, 2015, Volume: 129, Issue:2 Topics: Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; Forensic Toxicology; Hair; Humans; Limit of Detection; Psychotropic Drugs; Tandem Mass Spectrometry	2015
Production of monoclonal antibody against clonazepam for immunoassay of benzodiazepine drugs in swine tissues. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2015, Volume: 50, Issue:1 Topics: Animals; Antibodies, Monoclonal; Benzodiazepines; Clonazepam; Diazepam; Drug Residues; Flunitrazepam; Food Contamination; Haptens; Immunoassay; Kidney; Limit of Detection; Liver; Meat; Mice; Mice, Inbred BALB C; Muscles; Oxazepam; Serum Albumin; Swine; Tissue Distribution	2015
Has Previous Abuse of Flunitrazepam Been Replaced by Clonazepam? European addiction research, 2015, Volume: 21, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Automobile Driving; Clonazepam; Female; Flunitrazepam; Humans; Male; Middle Aged; Norway; Prescription Drug Diversion; Prescription Drug Misuse; Psychotropic Drugs; Young Adult	2015
Detection of Nitrobenzodiazepines and Their 7-Amino Metabolites in Oral Fluid. Journal of analytical toxicology, 2016, Volume: 40, Issue:4 Topics: Benzodiazepines; Clonazepam; Flunitrazepam; Humans; Nitrazepam; Opiate Substitution Treatment; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry	2016
Nitrobenzodiazepines: Postmortem brain and blood reference concentrations. Forensic science international, 2016, Volume: 268 Topics: Adolescent; Adult; Aged; Brain Chemistry; Chromatography, Liquid; Clonazepam; Female; Flunitrazepam; Forensic Toxicology; Humans; Male; Middle Aged; Nitrazepam; Postmortem Changes; Reference Values; Tandem Mass Spectrometry; Young Adult	2016