clonazepam and cgp 37157

clonazepam has been researched along with cgp 37157 in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (13.40)	18.2507
2000's	50 (51.55)	29.6817
2010's	33 (34.02)	24.3611
2020's	1 (1.03)	2.80

Authors

Authors	Studies
Conforti, L; Cox, DA; Matlib, MA; Sperelakis, N	1
Cox, DA; Matlib, MA	1
Reynolds, IJ; White, RJ	1
Griffiths, EJ; Haigney, MC; Ocampo, CJ; Silverman, HS; Stern, MD; Wei, SK	1
Hoyt, KR; Reynolds, IJ; Sharma, TA	1
Baron, KT; Thayer, SA	1
Cardman, JM; Hoyt, KR; Reynolds, IJ; Stout, AK	1
Hoyt, KR; Reynolds, IJ	1
Jornot, L; Junod, AF; Maechler, P; Wollheim, CB	1
Nishimura, S; Sorimachi, M; Yamagami, K	1
Brini, M; Davidson, M; King, MP; Pinton, P; Rizzuto, R; Schon, EA	1
David, G	1
Albillos, A; Alonso, MT; Alvarez, J; Carnicero, E; Cuchillo-Ibáñez, I; García, AG; García-Sancho, J; Montero, M	1
Ban, K; Chapman, RA; Handa, S	1
Albrecht, MA; Colegrove, SL; Friel, DD	2
Csordás, G; Hajnóczky, G; Hantash, BM; Szalai, G; Thomas, AP	1
Abercrombie, RF; Hille, B; Kaftan, EJ; Xu, T	1
Berman, SB; Hastings, TG; Watkins, SC	1
Albillos, A; Alonso, MT; Alvarez, J; García-Sancho, J; Montero, M	1
Arnaudeau, S; Demaurex, N; Kelley, WL; Walsh, JV	1
Adam-Vizi, V; Gerencsér AA, AA	1
Beaumont, V; Zhong, N; Zucker, RS	1
Thayer, SA; Wang, GJ	1
Bonanno, G; Raiteri, L; Raiteri, M; Stigliani, S; Zedda, L	1
Diaz, FG; O'Regan, MH; Phillis, JW; Pilitsis, JG	1
Grimaldi, M; Haak, LL; Russell, JT; Smaili, SS	1
Kito, Y; Suzuki, H	1
Ho, HC; Suarez, SS	1
Anderson, CM; Glasco, S; Grako, KA; Kornbrust, ES; Kushnareva, Y; Lee, B; Luan, P; Maechler, P; Miles, PD; Olefsky, JM; Vargas, L; Wollheim, CB	1
Benfenati, F; Bonanno, G; Giovedì, S; Raiteri, L; Raiteri, M	1
Bouchard, R; Choptiany, P; Hnatowich, M; Hryshko, LV; Le, HD; Omelchenko, A; Visen, N	1
Aydin, J; Bruton, J; Lännergren, J; Tavi, P; Westerblad, H	1
Demaurex, N; Frieden, M; Graier, WF; Malli, R; Mayer, M; Osibow, K; Zoratti, C	1
Czyz, A; Kiedrowski, L	1
Cheranov, SY; Jaggar, JH	1
Bruton, JD; Lännergren, J	1
de Groot, T; Koenderink, JB; Koopman, WJ; Mitchell, KJ; Rutter, GA; Smeitink, JA; van den Heuvel, LP; Varadi, A; Verkaart, S; Visch, HJ; Willems, PH	1
Joubert, F; Kaasik, A; Veksler, V; Ventura-Clapier, R	1
Feltmann, AJ; Froman, DP	1
Kahlert, S; Martínez-Sánchez, M; Reiser, G; Reymann, KG; Schröder, UH; Striggow, F	1
Duszyński, J; Szczepanowska, J; Zabłocki, K	1
Frieden, M; Graier, WF; Malli, R; Trenker, M	1
Heinemann, U; Kann, O; Kardos, J; Kovács, R	1
Adachi, S; Akiba, S; Hamahata, K; Imai, T; Katanosaka, Y; Kubota, M; Matsubara, H; Nakahata, T; Okada, M; Toyokuni, SY; Ueno, M; Wakabayashi, S; Watanabe, K	1
Allana, T; Fu, Q; Lin, JW	1
Boriboun, C; Marks, JD; Wang, J	1
Pasantes-Morales, H; Tuz, K	1
Borroni, P; Canciani, L; Frigo, G; Giaroni, C; Giuliani, D; Lecchini, S; Zanetti, E	1
Frank, S; Graier, WF; Malli, R; Osibow, K; Zechner, R	1
Jun, JY; Kim, BJ; Kim, KW; So, I	1
Kaddour-Djebbar, I; Kumar, MV; Lakshmikanthan, V; Lewis, RW; Ma, Y; Shirley, RB	1
Ahn, JR; Thu, le T; Woo, SH	1
Alvarez, J; Hernández-Sanmiguel, E; Lobatón, CD; Montero, M; Moreno, A; Santo-Domingo, J; Vay, L	1
Caplanusi, A; Fuller, AJ; Gonzalez-Villalobos, RA; Hammond, TG; Navar, LG	1
Ao, P; Hu, X; Johnson, JD; Luciani, DS; Warnock, GL	1
Blanck, TJ; Corrales, A; Montoya G, JV; Recio-Pinto, E; Sutachan, JJ; Xu, F	1
Parpura, V; Reyes, RC	1
Ardón, F; Beltrán, C; Darszon, A; Hernández-Cruz, A; Rodríguez-Miranda, E	1
Demaurex, N; Liao, CH; Poburko, D; van Breemen, C	1
Cortés, L; de Diego, AM; Egea, J; García, AG; González, JC; Hernández-Guijo, JM; López, MG; Mosquera, M; Nicolau, SM	1
Chalmers, S; McCarron, JG	1
Fekete, A; Franklin, L; Ikemoto, T; Lendvai, B; Rózsa, B; Sylvester Vizi, E; Zelles, T	1
Da Cruz, S; De Marchi, U; Demaurex, N; Frieden, M; Martinou, JC; Parone, PA	1
Caporale, T; Fishman, D; Herrmann, S; Hershfinkel, M; Khananshvili, D; Nolte, C; Palty, R; Parnis, J; Sekler, I; Sensi, SL; Shoshan-Barmatz, V; Silverman, WF	1
Brooks, C; Choudhary, V; Dong, Z; Ghazaly, T; Kaddour-Djebbar, I; Kumar, MV; Lakshmikanthan, V	1
Fedida-Metula, S; Feldman, B; Fishman, D; Nita, J; Sekler, I	1
Brown, DA; Liu, T; O'Rourke, B	1
Egea, J; García, AG; López, MG; Nicolau, SM	1
Hashiatni, H; Hashitani, H; Lang, RJ; Suzuki, H	1
Copello, JA; Diaz-Sylvester, PL; Fleischer, S; Neumann, JT	1
Bondarenko, OI; Sahach, VF	1
Chang, Y; Lin, YW; Wang, SJ	1
Chou, SH; Chou, SS; Huang, RF; Huang, SK; Kuo, YC; Leu, CY; Liew, YF; Lin, TY; Lu, CW; Tzeng, WF; Wang, SJ	1
Beswick, W; Cramb, G; Guild, SB; Millar, RP; Morgan, K; Popovics, P; Stewart, AJ	1
Case, S; Grald, A; Johnson, DI; Shea, K; Yargosz, P	1
Chen, X; Cui, S; Ding, R; Feng, Z; Fu, B; Hong, Q; Huang, Z; Qi, K; Wang, L; Wu, D; Yang, J	1
Beconi, MT; Rodriguez, PC; Satorre, MM	1
Choi, KS; Kim, EH; Kwon, TK; Park, SA; Yoon, MJ	1
Lakatta, EG; Lyashkov, AE; Maltsev, VA; Spurgeon, HA; Yang, D; Yaniv, Y; Ziman, BD	1
Delmotte, P; Pabelick, CM; Prakash, YS; Sieck, GC; Thompson, MA; Yang, B	1
de Los Ríos, C; Egea, J; García, AG; García-De Diego, AM; González-Lafuente, L; León, R; López, MG; Martínez-Sanz, FJ; Merino, C; Monjas, L; Perez, C; Rodríguez-Franco, MI; Villarroya, M	1
Chang, Y; Huang, SK; Wang, SJ	1
Grosskreutz, J; Lautenschläger, J; Prell, T; Ruhmer, J; Weidemann, L; Witte, OW	1
Clapham, D; Jiang, D; Miller, C; Tsai, MF; Zhao, L	1
Alaisami, R; Bollag, WB; Choudhary, V; Kaddour-Djebbar, I; Kumar, MV	1
Alberdi, E; Matute, C; Ruiz, A	1
Abraham, TP; DeMazumder, D; Dimaano, VL; Kettlewell, S; Liu, T; O'Rourke, B; Sidor, A; Smith, G; Takimoto, E	1
Castelbou, C; De Marchi, U; Demaurex, N; Santo-Domingo, J; Sekler, I; Wiederkehr, A	1
Bas, E; Gupta, C; Lumbreras, V; Rajguru, SM	1
Hamaguchi, S; Namekata, I; Tanaka, H	1
Cano-Abad, MF; de Los Rios, C; Lajarín-Cuesta, R; Martínez-Sanz, FJ; Moreno-Ortega, AJ	1
Froelich, K; Ginzkey, C; Hackenberg, S; Hagen, R; Kleinsasser, N; Rak, K; Schendzielorz, P; Scherzed, A	1
Hikida, M; Kim, B; Matsuoka, S; Takeuchi, A	1
Dietl, A; Maack, C	1
Ohshima, Y; Suzuki-Karasaki, M; Suzuki-Karasaki, Y; Takata, N; Tokuhashi, Y; Yoshida, Y	1
Hamaguchi, S; Namekata, I; Odaka, R; Tanaka, H	1

Reviews

1 review(s) available for clonazepam and cgp 37157

Article	Year
Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure. Current heart failure reports, 2017, Volume: 14, Issue:4 Topics: Antioxidants; Benzhydryl Compounds; Calcium; Clonazepam; Glucosides; Heart Failure; Humans; Mitochondria, Heart; Oxidation-Reduction; Oxidative Stress; Ranolazine; Reactive Oxygen Species; Risk Factors; Thiazepines	2017

Other Studies

96 other study(ies) available for clonazepam and cgp 37157

Article	Year
Selectivity of inhibition of Na(+)-Ca2+ exchange of heart mitochondria by benzothiazepine CGP-37157. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:4 Topics: Animals; Calcium; Clonazepam; Diltiazem; Male; Mitochondria, Heart; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Thiazepines	1993
A role for the mitochondrial Na(+)-Ca2+ exchanger in the regulation of oxidative phosphorylation in isolated heart mitochondria. The Journal of biological chemistry, 1993, Jan-15, Volume: 268, Issue:2 Topics: Animals; Calcium; Carrier Proteins; Cell Fractionation; Clonazepam; Diltiazem; Fura-2; Homeostasis; Male; Malonates; Mitochondria, Heart; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Sodium; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Thiazepines	1993
Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Sep-15, Volume: 16, Issue:18 Topics: Animals; Benzimidazoles; Calcium; Carbocyanines; Carrier Proteins; Cells, Cultured; Clonazepam; Electrophysiology; Fluorescent Dyes; Fluorometry; Glutamic Acid; Indoles; Membrane Potentials; Mitochondria; Neurons; Neurotoxins; Prosencephalon; Rats; Receptors, Glutamate; Sodium-Calcium Exchanger; Thiazepines	1996
Inhibition of mitochondrial calcium efflux by clonazepam in intact single rat cardiomyocytes and effects on NADH production. Cell calcium, 1997, Volume: 21, Issue:4 Topics: Animals; Anticonvulsants; Calcium; Carrier Proteins; Clonazepam; Cytosol; Mitochondria, Heart; Myocardial Contraction; NAD; Norepinephrine; Rats; Sodium-Calcium Exchanger; Thiazepines; Vasoconstrictor Agents	1997
Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones. British journal of pharmacology, 1997, Volume: 122, Issue:5 Topics: Animals; Benzimidazoles; Calcium; Carbocyanines; Cells, Cultured; Clonazepam; Dibucaine; Dizocilpine Maleate; Fluorescent Dyes; Fluorometry; Glutamic Acid; Membrane Potentials; Mitochondria; Neurons; Prosencephalon; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines; Trifluoperazine	1997
CGP37157 modulates mitochondrial Ca2+ homeostasis in cultured rat dorsal root ganglion neurons. European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3 Topics: Animals; Calcium; Cells, Cultured; Clonazepam; Enzyme Inhibitors; Fluorescent Dyes; Ganglia, Spinal; Homeostasis; Indoles; Mitochondria; Neurons; Rats; Sodium-Calcium Exchanger; Thiazepines	1997
The role of intracellular Na+ and mitochondria in buffering of kainate-induced intracellular free Ca2+ changes in rat forebrain neurones. The Journal of physiology, 1998, May-15, Volume: 509 ( Pt 1) Topics: Animals; Calcium; Cells, Cultured; Clonazepam; Excitatory Amino Acid Agonists; Fluorescent Dyes; Kainic Acid; Membrane Potentials; Mitochondria; Neurons; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Calcium Exchanger; Stimulation, Chemical; Thiazepines	1998
Alkalinization prolongs recovery from glutamate-induced increases in intracellular Ca2+ concentration by enhancing Ca2+ efflux through the mitochondrial Na+/Ca2+ exchanger in cultured rat forebrain neurons. Journal of neurochemistry, 1998, Volume: 71, Issue:3 Topics: Alkalies; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Glutamic Acid; Hydrogen-Ion Concentration; Intracellular Membranes; Mitochondria; Neurons; Osmolar Concentration; Prosencephalon; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines; Uncoupling Agents	1998
Reactive oxygen metabolites increase mitochondrial calcium in endothelial cells: implication of the Ca2+/Na+ exchanger. Journal of cell science, 1999, Volume: 112 ( Pt 7) Topics: Adenosine Triphosphate; Aequorin; Benzimidazoles; Calcium; Carbocyanines; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Clonazepam; Cytosol; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Flow Cytometry; Histamine; Humans; Hydrogen Peroxide; Indoles; Mitochondria; Reactive Oxygen Species; Sodium-Calcium Exchanger; Thiazepines; Time Factors; Transfection; Umbilical Veins; Xanthine Oxidase	1999
Sequestration of depolarization-induced Ca2+ loads by mitochondria and Ca2+ efflux via mitochondrial Na+/Ca2+ exchanger in bovine adrenal chromaffin cells. The Japanese journal of physiology, 1999, Volume: 49, Issue:1 Topics: Adrenal Glands; Animals; Calcium; Cattle; Chromaffin Cells; Clonazepam; GABA Modulators; Membrane Potentials; Mitochondria; Sodium-Calcium Exchanger; Thiazepines	1999
A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. Nature medicine, 1999, Volume: 5, Issue:8 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Calcium; Calcium Signaling; Cell Line; Clonazepam; DNA, Mitochondrial; Histamine; Humans; MERRF Syndrome; Mitochondria; Mitochondrial Encephalomyopathies; Oligomycins; Oxidative Phosphorylation; RNA, Transfer, Lys; Thiazepines; Transfection	1999
Mitochondrial clearance of cytosolic Ca(2+) in stimulated lizard motor nerve terminals proceeds without progressive elevation of mitochondrial matrix [Ca(2+)]. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Sep-01, Volume: 19, Issue:17 Topics: Action Potentials; Animals; Antimycin A; Axons; Caffeine; Calcium; Carbachol; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Clonazepam; Cytosol; Electric Stimulation; In Vitro Techniques; Indoles; Intracellular Membranes; Lizards; Membrane Potentials; Mitochondria, Muscle; Models, Biological; Motor Endplate; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Nerve Endings; Neuromuscular Junction; Oligomycins; Thiazepines; Tubocurarine	1999
Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion. Nature cell biology, 2000, Volume: 2, Issue:2 Topics: Acetylcholine; Adrenal Medulla; Animals; Biological Transport; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Catecholamines; Cattle; Cell Membrane; Chromaffin Cells; Clonazepam; Endoplasmic Reticulum; Mitochondria; Potassium; Ryanodine Receptor Calcium Release Channel; Sodium-Calcium Exchanger; Thiazepines	2000
On the mechanism of the failure of mitochondrial function in isolated guinea-pig myocytes subjected to a Ca2+ overload. Cardiovascular research, 1999, Volume: 44, Issue:3 Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Clonazepam; Cyclosporine; Depression, Chemical; Enzyme Inhibitors; Guinea Pigs; Intracellular Membranes; Magnesium; Male; Microscopy, Fluorescence; Mitochondria, Heart; NADH, NADPH Oxidoreductases; Ruthenium Red; Sodium; Sodium-Hydrogen Exchangers; Thiazepines	1999
Dissection of mitochondrial Ca2+ uptake and release fluxes in situ after depolarization-evoked [Ca2+](i) elevations in sympathetic neurons. The Journal of general physiology, 2000, Volume: 115, Issue:3 Topics: Animals; Biological Transport; Calcium; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Male; Mitochondria; Neurons; Patch-Clamp Techniques; Potassium; Rana catesbeiana; Sodium; Sympathetic Nervous System; Thiazepines; Uncoupling Agents	2000
Quantitative analysis of mitochondrial Ca2+ uptake and release pathways in sympathetic neurons. Reconstruction of the recovery after depolarization-evoked [Ca2+]i elevations. The Journal of general physiology, 2000, Volume: 115, Issue:3 Topics: Action Potentials; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Clonazepam; Electrophysiology; Male; Membrane Potentials; Mitochondria; Neurons; Potassium; Rana catesbeiana; Sodium-Calcium Exchanger; Stimulation, Chemical; Sympathetic Nervous System; Thiazepines; Uncoupling Agents	2000
Calcium signal transmission between ryanodine receptors and mitochondria. The Journal of biological chemistry, 2000, May-19, Volume: 275, Issue:20 Topics: Animals; Caffeine; Calcium; Calcium Channels, L-Type; Cell Line; Cell Membrane Permeability; Clonazepam; Egtazic Acid; Kinetics; Mitochondria, Heart; Muscle, Skeletal; Myocardium; NAD; NADP; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Thiazepines; Transfection	2000
Mitochondria shape hormonally induced cytoplasmic calcium oscillations and modulate exocytosis. The Journal of biological chemistry, 2000, Aug-18, Volume: 275, Issue:33 Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Castration; Cell Membrane; Cells, Cultured; Clonazepam; Cytoplasm; Electrophysiology; Exocytosis; Fluorescent Dyes; Gonadotropin-Releasing Hormone; Heterocyclic Compounds, 3-Ring; Ionophores; Male; Microscopy, Confocal; Mitochondria; Organic Chemicals; Pituitary Gland; Rats; Sodium-Calcium Exchanger; Thiazepines; Time Factors	2000
Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria. Experimental neurology, 2000, Volume: 164, Issue:2 Topics: Animals; Arsenicals; Brain; Calcium; Clonazepam; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Intercellular Signaling Peptides and Proteins; Ion Channels; Liver; Male; Membrane Proteins; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Peptides; Phosphates; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Thiazepines; Wasp Venoms	2000
Mitochondrial Ca(2+)-induced Ca(2+) release mediated by the Ca(2+) uniporter. Molecular biology of the cell, 2001, Volume: 12, Issue:1 Topics: Aequorin; Animals; Calcium; Calcium Channels; Calcium-Binding Proteins; Cattle; Chromaffin Cells; Clonazepam; Cyclosporine; Luminescent Proteins; Mitochondria; Potassium; Ruthenium Red; Thiazepines	2001
Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions. The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31 Topics: Calcium; Calcium-Transporting ATPases; Cell Line; Clonazepam; Cytosol; Endoplasmic Reticulum; Fluorescent Dyes; HeLa Cells; Histamine; Humans; Hydrogen-Ion Concentration; Kinetics; Mitochondria; Oligomycins; Rotenone; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thiazepines	2001
Selective, high-resolution fluorescence imaging of mitochondrial Ca2+ concentration. Cell calcium, 2001, Volume: 30, Issue:5 Topics: Adenosine Triphosphate; Animals; Brain; Calcium; Cells, Cultured; Clonazepam; Endothelium, Vascular; Fluorescent Dyes; Image Processing, Computer-Assisted; Ion Transport; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Rats; Rats, Inbred Lew; Ruthenium Compounds; Thiazepines	2001
Roles for mitochondrial and reverse mode Na+/Ca2+ exchange and the plasmalemma Ca2+ ATPase in post-tetanic potentiation at crayfish neuromuscular junctions. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Dec-15, Volume: 21, Issue:24 Topics: Action Potentials; Animals; Astacoidea; Calcium; Calcium-Transporting ATPases; Clonazepam; Electric Stimulation; Enzyme Inhibitors; Fluorescent Dyes; In Vitro Techniques; Ion Transport; Microinjections; Mitochondria; Neuromuscular Junction; Ouabain; Sodium; Sodium-Calcium Exchanger; Thiazepines; Thiourea	2001
NMDA-induced calcium loads recycle across the mitochondrial inner membrane of hippocampal neurons in culture. Journal of neurophysiology, 2002, Volume: 87, Issue:2 Topics: Animals; Calcium; Calcium Channels; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Coloring Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Hippocampus; Mitochondria; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sodium; Sodium-Calcium Exchanger; Thiazepines; Uncoupling Agents	2002
Multiple mechanisms of transmitter release evoked by "pathologically" elevated extracellular [K+]: involvement of transporter reversal and mitochondrial calcium. Journal of neurochemistry, 2002, Volume: 80, Issue:4 Topics: Animals; Anticonvulsants; Brain Chemistry; Calcium; Carrier Proteins; Cerebral Cortex; Chelating Agents; Clonazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exocytosis; Extracellular Space; Fluorescent Dyes; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Male; Membrane Proteins; Membrane Transport Proteins; Nicotinic Acids; Organic Anion Transporters; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Synaptosomes; Thiazepines; Tritium	2002
Inhibition of mitochondrial Na(+)/Ca(2+) exchange by 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2 Topics: Animals; Calcium; Cell Death; Cerebral Cortex; Clonazepam; Fatty Acids, Nonesterified; Hypoxia-Ischemia, Brain; Intracellular Fluid; Male; Mitochondria; Neurons; Neuroprotective Agents; Phospholipases A; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Calcium Exchanger; Thiazepines	2002
Mitochondria regulate Ca2+ wave initiation and inositol trisphosphate signal transduction in oligodendrocyte progenitors. Journal of neurochemistry, 2002, Volume: 80, Issue:3 Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Antimycin A; Calcium; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Gelsolin; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Methacholine Chloride; Mitochondria; Muscarinic Antagonists; Oligodendroglia; Phosphatidylinositol 4,5-Diphosphate; Rats; Stem Cells; Thiazepines; Uncoupling Agents	2002
Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. The Journal of physiology, 2003, Jan-01, Volume: 546, Issue:Pt 1 Topics: Aminoglycosides; Animals; Calcium; Clonazepam; Cobalt; Electrophysiology; Female; Genistein; Guinea Pigs; In Vitro Techniques; Intracellular Membranes; Male; Mitochondria, Muscle; Nickel; Nitric Oxide Donors; Nitroprusside; Periodicity; Pyloric Antrum; Sodium-Calcium Exchanger; Thiazepines; Time Factors	2003
Characterization of the intracellular calcium store at the base of the sperm flagellum that regulates hyperactivated motility. Biology of reproduction, 2003, Volume: 68, Issue:5 Topics: Adenosine Triphosphate; Animals; Calcium; Calreticulin; Cattle; Clonazepam; Fluorescent Antibody Technique, Indirect; In Vitro Techniques; Male; Microscopy, Electron; Microscopy, Immunoelectron; Mitochondria; NAD; Nuclear Envelope; Sperm Motility; Sperm Tail; Spermatozoa; Thiazepines	2003
Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets. Diabetes, 2003, Volume: 52, Issue:4 Topics: Adenosine Triphosphate; Aequorin; Animals; Calcium; Cell Line; Cell Membrane; Clonazepam; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mitochondria; NAD; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Calcium Exchanger; Thiazepines; Transfection	2003
Cellular mechanisms of the acute increase of glutamate release induced by nerve growth factor in rat cerebral cortex. Neuropharmacology, 2003, Volume: 44, Issue:3 Topics: Animals; Animals, Newborn; Anticoagulants; Benzylamines; Blotting, Western; Caffeine; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Central Nervous System Stimulants; Cerebral Cortex; Clonazepam; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Fura-2; Glutamic Acid; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinase Kinases; Muscle Relaxants, Central; Nerve Growth Factor; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Proto-Oncogenes; Rats; Rats, Sprague-Dawley; Receptor, trkA; Sulfonamides; Synapsins; Synaptosomes; Thiazepines	2003
Inhibition of canine (NCX1.1) and Drosophila (CALX1.1) Na(+)-Ca(2+) exchangers by 7-chloro-3,5-dihydro-5-phenyl-1H-4,1-benzothiazepine-2-one (CGP-37157). The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:3 Topics: Animals; Calcium; Clonazepam; Dogs; Drosophila melanogaster; Electrophysiology; Sodium; Sodium-Calcium Exchanger; Species Specificity; Thiazepines	2003
Mitochondrial and myoplasmic [Ca2+] in single fibres from mouse limb muscles during repeated tetanic contractions. The Journal of physiology, 2003, Aug-15, Volume: 551, Issue:Pt 1 Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Electric Stimulation; Extremities; Fluorescent Dyes; Heterocyclic Compounds, 3-Ring; Intracellular Membranes; Ionophores; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Mitochondria, Muscle; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Osmolar Concentration; Thiazepines	2003
Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling. The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45 Topics: Biological Transport; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Clonazepam; Electric Capacitance; Endoplasmic Reticulum; Endothelium, Vascular; Histamine; Humans; Membrane Potentials; Mitochondria; Patch-Clamp Techniques; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sodium; Sodium-Calcium Exchanger; Thiazepines; Umbilical Veins	2003
Inhibition of plasmalemmal Na(+)/Ca(2+) exchange by mitochondrial Na(+)/Ca(2+) exchange inhibitor 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one (CGP-37157) in cerebellar granule cells. Biochemical pharmacology, 2003, Dec-15, Volume: 66, Issue:12 Topics: Animals; Cerebellum; Clonazepam; Mitochondria; Neurons; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines	2003
Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries. The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3 Topics: Animals; Bongkrekic Acid; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cerebral Arteries; Clonazepam; Cyclosporine; Diltiazem; Female; Hydrogen Peroxide; Indazoles; Ion Channels; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Oligomycins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Ruthenium Compounds; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Thapsigargin; Thiazepines	2004
Mitochondrial Ca2+ in mouse soleus single muscle fibres in response to repeated tetanic contractions. Advances in experimental medicine and biology, 2003, Volume: 538 Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Ionophores; Isometric Contraction; Male; Mice; Mitochondria; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Sodium-Calcium Exchanger; Thiazepines; Uncoupling Agents	2003
Inhibition of mitochondrial Na+-Ca2+ exchange restores agonist-induced ATP production and Ca2+ handling in human complex I deficiency. The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39 Topics: Adenosine Triphosphate; Bradykinin; Calcium; Cell Nucleus; Clonazepam; Cytosol; Electron Transport Complex I; Fibroblasts; Fluorescent Dyes; Humans; Ionomycin; Leigh Disease; Luciferases; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Mitochondrial Encephalomyopathies; Oxygen; Parkinson Disease; Skin; Sodium-Calcium Exchanger; Thiazepines; Time Factors	2004
A novel mechanism of regulation of cardiac contractility by mitochondrial functional state. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:11 Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Bongkrekic Acid; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Compartmentation; Clonazepam; Creatine Kinase; Creatine Kinase, Mitochondrial Form; Creatine Kinase, MM Form; Electron Transport; Energy Metabolism; Ion Transport; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocardial Contraction; Myofibrils; Nigericin; Oligomycins; Pinacidil; Potassium; Potassium-Hydrogen Antiporters; Quinine; Rats; Ruthenium Red; Sarcomeres; Sarcoplasmic Reticulum; Sodium Azide; Sodium-Calcium Exchanger; Stress, Mechanical; Tetraethylammonium; Thapsigargin; Thiazepines; Valinomycin	2004
Fowl (Gallus domesticus) sperm motility depends upon mitochondrial calcium cycling driven by extracellular sodium. Biology of reproduction, 2005, Volume: 72, Issue:1 Topics: Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Chickens; Clonazepam; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix; Lithium Chloride; Male; Mitochondria; Ouabain; Sodium; Sodium-Calcium Exchanger; Sperm Motility; Thiazepines; Thiourea	2005
Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures. Neuroscience, 2004, Volume: 128, Issue:4 Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blockers; Cell Death; Clonazepam; Dantrolene; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; Glucose; Hippocampus; Hypoxia; In Situ Nick-End Labeling; Indoles; Intracellular Space; Ion Exchange; Lidocaine; Mibefradil; Nimodipine; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Thiazepines; Thiourea; Time Factors	2004
Extracellular pH modifies mitochondrial control of capacitative calcium entry in Jurkat cells. The Journal of biological chemistry, 2005, Feb-04, Volume: 280, Issue:5 Topics: Anti-Bacterial Agents; Antimycin A; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Clonazepam; Extracellular Space; Humans; Hydrogen-Ion Concentration; Jurkat Cells; Mitochondria; Oligomycins; Osteosarcoma; Thiazepines; Uncoupling Agents	2005
The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum. The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13 Topics: Calcium; Calcium-Transporting ATPases; Cells, Cultured; Clonazepam; Cytoplasm; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Endothelium, Vascular; Histamine; Humans; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Mitochondria; Models, Biological; Plasmids; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thiazepines; Time Factors; Transfection; Umbilical Veins	2005
Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-27, Volume: 25, Issue:17 Topics: Animals; Animals, Newborn; Calcium; Calcium Signaling; Clonazepam; Dose-Response Relationship, Radiation; Electric Stimulation; Epilepsy; Fluorescent Dyes; Hippocampus; Imaging, Three-Dimensional; In Vitro Techniques; Ion Exchange; Membrane Potentials; Microscopy, Confocal; Mitochondria; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazepines	2005
Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells. European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3 Topics: Apoptosis; Calcimycin; Calcium; Caspase 3; Caspases; Cell Line, Tumor; Cell Shape; Clonazepam; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; HL-60 Cells; Humans; Intracellular Membranes; Ionophores; Membrane Potentials; Mitochondria; Necrosis; Phospholipases; Proto-Oncogene Proteins c-bcl-2; Thiazepines; Time Factors	2005
Probing the endogenous Ca2+ buffers at the presynaptic terminals of the crayfish neuromuscular junction. Journal of neurophysiology, 2005, Volume: 94, Issue:1 Topics: Action Potentials; Animals; Astacoidea; Buffers; Calcium; Clonazepam; Computer Simulation; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Fluorescent Dyes; In Vitro Techniques; Lithium; Neural Inhibition; Neuromuscular Junction; Presynaptic Terminals; Sodium; Sodium-Calcium Exchanger; Thapsigargin; Thiazepines; Thiourea; Time Factors	2005
Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-13, Volume: 25, Issue:28 Topics: Animals; Animals, Newborn; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Hippocampus; Indazoles; Ion Transport; Mitochondria; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Oxygen; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Compounds; Thiazepines	2005
Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization- and Ca2+ -dependent exocytotic mechanism. The European journal of neuroscience, 2005, Volume: 22, Issue:7 Topics: Animals; Barium; Cadmium; Calcium; Calcium Channel Blockers; Carbazoles; Cerebral Cortex; Clonazepam; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Indoles; Lanthanum; Norepinephrine; omega-Conotoxins; Osmolar Concentration; Phorbol Esters; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Ruthenium Red; Sodium; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Synaptosomes; Tetanus Toxin; Thiazepines; Time Factors; Tritium	2005
Involvement of glutamate receptors of the NMDA type in the modulation of acetylcholine and glutamate overflow from the guinea pig ileum during in vitro hypoxia and hypoglycaemia. Neurochemistry international, 2006, Volume: 48, Issue:3 Topics: Acetylcholine; Animals; Clonazepam; Endoplasmic Reticulum; Glucose; Glutamic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mitochondria; Oxygen; Receptors, N-Methyl-D-Aspartate; Thapsigargin; Thiazepines	2006
Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum. The Biochemical journal, 2006, May-15, Volume: 396, Issue:1 Topics: Adenoviridae; Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; CHO Cells; Clonazepam; Cricetinae; Cricetulus; Endoplasmic Reticulum; Endothelial Cells; Genetic Vectors; Histamine; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Mitochondria; Protein Folding; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Thiazepines	2006
Involvement of mitochondrial Na+-Ca2+ exchange in intestinal pacemaking activity. World journal of gastroenterology, 2006, Feb-07, Volume: 12, Issue:5 Topics: Animals; Biological Clocks; Clonazepam; Female; In Vitro Techniques; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Mitochondria; Nickel; Patch-Clamp Techniques; Sodium-Calcium Exchanger; Thiazepines	2006
Therapeutic advantage of combining calcium channel blockers and TRAIL in prostate cancer. Molecular cancer therapeutics, 2006, Volume: 5, Issue:8 Topics: Androgens; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Calcium Channel Blockers; Clonazepam; Drug Synergism; Humans; Male; Mitochondria; Prostatic Neoplasms; Sodium-Calcium Exchanger; Thiazepines; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured	2006
Inhibition of L-type Ca2+ channel by mitochondrial Na+-Ca2+ exchange inhibitor CGP-37157 in rat atrial myocytes. European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3 Topics: Animals; Barium; Calcium Channel Blockers; Calcium Channels, L-Type; Chelating Agents; Clonazepam; Diltiazem; Dose-Response Relationship, Drug; Egtazic Acid; Heart Atria; Ion Channels; Male; Membrane Potentials; Mitochondrial Proteins; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines	2006
Modulation of Ca(2+) release and Ca(2+) oscillations in HeLa cells and fibroblasts by mitochondrial Ca(2+) uniporter stimulation. The Journal of physiology, 2007, Apr-01, Volume: 580, Issue:Pt 1 Topics: Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Clonazepam; Cytosol; Endoplasmic Reticulum; Estrogen Antagonists; Fibroblasts; HeLa Cells; Histamine; Humans; Inositol 1,4,5-Trisphosphate Receptors; Kaempferols; Mitochondria; Stimulation, Chemical; Thiazepines	2007
Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line. American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:2 Topics: Adenosine Triphosphate; Antimetabolites; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Clonazepam; Humans; Kidney Tubules, Proximal; Membrane Potentials; Mitochondria; Sodium; Sodium-Calcium Exchanger; Thiazepines; Uncoupling Agents	2007
Voltage-gated Ca(2+) influx and insulin secretion in human and mouse beta-cells are impaired by the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP-37157. European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3 Topics: Animals; Calcium; Cells, Cultured; Clonazepam; Glucose; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mitochondria; Potassium Chloride; Sodium-Calcium Exchanger; Thiazepines	2007
Pulses of extracellular K+ produce two cytosolic Ca2+ transients that display different temperature dependence and carbonyl cyanide m-chlorophenyl sensitivity in SH-SY5Y cells. Brain research, 2008, Jun-05, Volume: 1213 Topics: Anticonvulsants; Caffeine; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Clonazepam; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Humans; Ionophores; Neuroblastoma; Nitriles; Phosphodiesterase Inhibitors; Potassium Chloride; Temperature; Thiazepines; Time Factors	2008
Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-24, Volume: 28, Issue:39 Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Survival; Cells, Cultured; Clonazepam; Cyclosporine; Cytosol; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Mitochondria; Oligomycins; Physical Stimulation; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Ruthenium Compounds; Secretory Vesicles; Sugar Alcohol Dehydrogenases; Thiazepines; Visual Cortex	2008
Mitochondrial inhibitors activate influx of external Ca(2+) in sea urchin sperm. Biochimica et biophysica acta, 2009, Volume: 1787, Issue:1 Topics: Animals; Antimycin A; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations; Clonazepam; Electron Transport; Gadolinium; Imidazoles; Male; Mitochondria; Nickel; Oligomycins; Proton-Translocating ATPases; Sea Urchins; Sodium-Calcium Exchanger; Spermatozoa; Thiazepines; Uncoupling Agents	2009
Mitochondrial regulation of sarcoplasmic reticulum Ca2+ content in vascular smooth muscle cells. Circulation research, 2009, Jan-02, Volume: 104, Issue:1 Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Calcium Signaling; Cell Compartmentation; Cell Membrane; Clonazepam; Hypertension; Membrane Proteins; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Recombinant Fusion Proteins; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger; Thiazepines; Thiourea	2009
Mitochondrial Na+/Ca2+-exchanger blocker CGP37157 protects against chromaffin cell death elicited by veratridine. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:3 Topics: Animals; Calcium Channels; Calcium Signaling; Cattle; Cell Death; Cells, Cultured; Chromaffin Cells; Clonazepam; Coloring Agents; Cytochromes c; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Patch-Clamp Techniques; Reactive Oxygen Species; Sodium Channels; Sodium-Calcium Exchanger; Tetrazolium Salts; Thiazepines; Thiazoles; Veratridine	2009
Inhibition of mitochondrial calcium uptake rather than efflux impedes calcium release by inositol-1,4,5-trisphosphate-sensitive receptors. Cell calcium, 2009, Volume: 46, Issue:2 Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Clonazepam; Cytosol; Feedback, Physiological; Guinea Pigs; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Male; Microscopy, Fluorescence; Mitochondria, Muscle; Myocytes, Smooth Muscle; Sarcoplasmic Reticulum; Thiazepines	2009
Mechanism of the persistent sodium current activator veratridine-evoked Ca elevation: implication for epilepsy. Journal of neurochemistry, 2009, Volume: 111, Issue:3 Topics: Animals; Animals, Newborn; Anticonvulsants; Biophysics; Cadmium Chloride; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Clonazepam; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Ionophores; Male; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Thapsigargin; Thiazepines; Veratridine	2009
SLP-2 negatively modulates mitochondrial sodium-calcium exchange. Cell calcium, 2010, Volume: 47, Issue:1 Topics: Blood Proteins; Calcium; Calcium Signaling; Clonazepam; Cytosol; HeLa Cells; Humans; Membrane Proteins; Mitochondria; Mitochondrial Membranes; RNA, Small Interfering; Sodium; Sodium-Calcium Exchanger; Thiazepines	2010
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-05, Volume: 107, Issue:1 Topics: Animals; Brain; Calcium; Clonazepam; Homeostasis; Humans; Mice; Mitochondria; Mitochondrial Membranes; Myocardium; Rats; Sodium; Sodium-Calcium Exchanger; Thiazepines	2010
Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells. International journal of oncology, 2010, Volume: 36, Issue:6 Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting, Western; Calcium; Cell Line, Tumor; Clonazepam; Dynamins; GTP Phosphohydrolases; Humans; Immunohistochemistry; Immunoprecipitation; Male; Membrane Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Prostatic Neoplasms; Sodium-Calcium Exchanger; Thiazepines; TNF-Related Apoptosis-Inducing Ligand; Transfection	2010
Coupling of mitochondria to store-operated Ca(2+)-signaling sustains constitutive activation of protein kinase B/Akt and augments survival of malignant melanoma cells. Cell calcium, 2010, Volume: 47, Issue:6 Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Survival; Clonazepam; Flow Cytometry; Melanoma; Mice; Mitochondria; Proto-Oncogene Proteins c-akt; Sodium-Calcium Exchanger; Thiazepines	2010
Role of mitochondrial dysfunction in cardiac glycoside toxicity. Journal of molecular and cellular cardiology, 2010, Volume: 49, Issue:5 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Glycosides; Clonazepam; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Mitochondria; NAD; Ouabain; Oxygen Consumption; Perfusion; Sodium; Sodium-Calcium Exchanger; Thiazepines	2010
Mitochondrial Na+/Ca2+ exchanger, a new target for neuroprotection in rat hippocampal slices. Biochemical and biophysical research communications, 2010, Sep-10, Volume: 400, Issue:1 Topics: Animals; Clonazepam; Cytoprotection; Hippocampus; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines; Veratridine	2010
Role of perinuclear mitochondria in the spatiotemporal dynamics of spontaneous Ca2+ waves in interstitial cells of Cajal-like cells of the rabbit urethra. British journal of pharmacology, 2010, Volume: 161, Issue:3 Topics: Animals; Caffeine; Calcium; Calcium Signaling; Clonazepam; Deoxyglucose; Endoplasmic Reticulum; Glycolysis; Hydrazones; Indoles; Interstitial Cells of Cajal; Male; Mitochondria; Rabbits; Ruthenium Compounds; Ryanodine; Thiazepines; Urethra	2010
CGP-37157 inhibits the sarcoplasmic reticulum Ca²+ ATPase and activates ryanodine receptor channels in striated muscle. Molecular pharmacology, 2011, Volume: 79, Issue:1 Topics: Animals; Calcium; Calcium-Transporting ATPases; Clonazepam; Muscle, Striated; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Thiazepines	2011
[Mitochondrial Na+-Ca2+-exchanger inhibitor CGP37157 produces endothelial cell depolarization with membrane potential oscillations]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:1 Topics: Animals; Aorta, Thoracic; Cell Culture Techniques; Cell Polarity; Cells, Cultured; Clonazepam; Endothelial Cells; Endothelium, Vascular; Histamine; Membrane Potentials; Mitochondria; Patch-Clamp Techniques; Rats; Sodium-Calcium Exchanger; Thiazepines	2011
Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A. Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1 Topics: 4-Aminopyridine; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbazoles; Cerebral Cortex; Clonazepam; Cyclic AMP-Dependent Protein Kinases; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Indoles; Isoquinolines; Macrolides; Male; Maleimides; Membrane Potentials; Nerve Endings; omega-Conotoxins; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sulfonamides; Synaptosomes; Thiazepines; Ubiquinone	2011
HTDP-2, a new synthetic compound, inhibits glutamate release through reduction of voltage-dependent Ca²⁺ influx in rat cerebral cortex nerve terminals. Pharmacology, 2011, Volume: 88, Issue:1-2 Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Clonazepam; Cytosol; Dantrolene; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Glutamic Acid; Male; Membrane Potentials; Nerve Endings; Neuroprotective Agents; Potassium Channel Blockers; Pyridones; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Synaptosomes; Thiazepines; Tosyl Compounds	2011
Phospholipase C-η2 is activated by elevated intracellular Ca(2+) levels. Cellular signalling, 2011, Volume: 23, Issue:11 Topics: Animals; Binding Sites; Blotting, Western; Calcium; Chlorocebus aethiops; Clonazepam; COS Cells; Enzyme Activation; Inositol Phosphates; Microscopy, Confocal; Mitochondria; Monensin; Mutagenesis, Site-Directed; Mutation; Phosphoinositide Phospholipase C; Plasmids; Protein Structure, Tertiary; Signal Transduction; Sodium Ionophores; Sodium-Calcium Exchanger; Thiazepines; Transfection	2011
Small-molecule inhibitors of biofilm formation in laboratory and clinical isolates of Candida albicans. Journal of medical microbiology, 2012, Volume: 61, Issue:Pt 1 Topics: 5,8,11,14-Eicosatetraynoic Acid; Antifungal Agents; Biofilms; Candida albicans; Candidiasis; Clonazepam; Culture Media; Humans; Hyphae; Microbial Sensitivity Tests; Signal Transduction; Thiazepines	2012
Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload. Cell calcium, 2012, Volume: 51, Issue:5 Topics: Calcium; Clonazepam; Cytoplasm; Endothelium; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hyperuricemia; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Oxygen; Reactive Oxygen Species; Sodium-Calcium Exchanger; Thiazepines; Uric Acid	2012
Effect of two intracellular calcium modulators on sperm motility and heparin-induced capacitation in cryopreserved bovine spermatozoa. Animal reproduction science, 2012, Volume: 131, Issue:3-4 Topics: Animals; Calcium; Cattle; Clonazepam; Cryopreservation; Heparin; Male; Ruthenium Compounds; Semen Preservation; Sperm Capacitation; Sperm Motility; Spermatozoa; Thiazepines	2012
Simultaneous mitochondrial Ca(2+) overload and proteasomal inhibition are responsible for the induction of paraptosis in malignant breast cancer cells. Cancer letters, 2012, Nov-28, Volume: 324, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Breast Neoplasms; Calcium; Cell Death; Cell Line, Tumor; Clonazepam; Curcumin; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Humans; Mitochondria; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Sodium-Calcium Exchanger; Thiazepines; Time Factors	2012
Crosstalk between mitochondrial and sarcoplasmic reticulum Ca2+ cycling modulates cardiac pacemaker cell automaticity. PloS one, 2012, Volume: 7, Issue:5 Topics: Action Potentials; Animals; Calcium; Clonazepam; Cytosol; Electric Conductivity; Heart Rate; Heart Ventricles; Indoles; Magnesium; Mitochondria; Models, Biological; Myocytes, Cardiac; Periodicity; Rabbits; Ruthenium Compounds; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sinoatrial Node; Thiazepines	2012
Inflammation alters regional mitochondrial Ca²+ in human airway smooth muscle cells. American journal of physiology. Cell physiology, 2012, Aug-01, Volume: 303, Issue:3 Topics: Aniline Compounds; Bronchi; Calcium; Calcium Signaling; Cells, Cultured; Clonazepam; Heterocyclic Compounds, 3-Ring; Histamine; Humans; Inflammation; Interleukin-13; Microscopy, Fluorescence; Mitochondria; Myocytes, Smooth Muscle; Ruthenium Compounds; Sodium-Calcium Exchanger; Thiazepines; Tumor Necrosis Factor-alpha; Xanthenes	2012
Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry. ACS chemical neuroscience, 2012, Jul-18, Volume: 3, Issue:7 Topics: Animals; Calcium; Calcium Channel Blockers; Cattle; Cell Line, Tumor; Cell Survival; Clonazepam; Hippocampus; Humans; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazepines	2012
Coenzyme Q10 inhibits the release of glutamate in rat cerebrocortical nerve terminals by suppression of voltage-dependent calcium influx and mitogen-activated protein kinase signaling pathway. Journal of agricultural and food chemistry, 2012, Dec-05, Volume: 60, Issue:48 Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cerebral Cortex; Clonazepam; Dantrolene; Glutamic Acid; Macrolides; Male; MAP Kinase Signaling System; Membrane Potentials; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Nerve Endings; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Synapsins; Synaptosomes; Thiazepines; Ubiquinone	2012
Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons. Experimental neurology, 2013, Volume: 247 Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Clonazepam; Embryo, Mammalian; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Motor Neurons; Ruthenium Compounds; Sodium Channel Blockers; Spinal Cord; Superoxide Dismutase; Tetrodotoxin; Thiazepines; Unfolded Protein Response; Verapamil	2013
Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1. The Journal of general physiology, 2014, Volume: 143, Issue:1 Topics: Antiporters; Calcium; Calcium-Binding Proteins; Cation Transport Proteins; Cations, Divalent; Clonazepam; Humans; Ion Transport; Liposomes; Membrane Proteins; Mitochondrial Proteins; Potassium; Ruthenium Red; Sodium; Thiazepines	2014
Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells. International journal of oncology, 2014, Volume: 44, Issue:5 Topics: Apoptosis; Calcium; Cell Line, Tumor; Clonazepam; Cycloheximide; GTP Phosphohydrolases; Humans; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Signal Transduction; Thiazepines; Ubiquitination	2014
CGP37157, an inhibitor of the mitochondrial Na+/Ca2+ exchanger, protects neurons from excitotoxicity by blocking voltage-gated Ca2+ channels. Cell death & disease, 2014, Apr-10, Volume: 5 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calpain; Cells, Cultured; Clonazepam; Cytoprotection; Cytosol; Endoplasmic Reticulum; Intracellular Space; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines	2014
Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure. Circulation research, 2014, Jun-20, Volume: 115, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Calcium; Cardiomegaly; Clonazepam; Death, Sudden, Cardiac; Disease Models, Animal; Electrocardiography; Guinea Pigs; Heart Failure; Heart Rate; Male; Oxidative Stress; Receptors, Adrenergic, beta; Sodium-Calcium Exchanger; Thiazepines	2014
NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state. The Journal of biological chemistry, 2014, Jul-18, Volume: 289, Issue:29 Topics: Calcium Signaling; Calcium-Binding Proteins; Clonazepam; HeLa Cells; Humans; Kinetics; Membrane Proteins; Mitochondria; Mitochondrial Proteins; NAD; NADP; Oxidation-Reduction; Recombinant Proteins; Sodium-Calcium Exchanger; Thiazepines	2014
Pulsed infrared radiation excites cultured neonatal spiral and vestibular ganglion neurons by modulating mitochondrial calcium cycling. Journal of neurophysiology, 2014, Sep-15, Volume: 112, Issue:6 Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Clonazepam; Indoles; Infrared Rays; Mitochondria; Neurons, Afferent; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Sodium Channel Blockers; Spiral Ganglion; Temperature; Thiazepines; Vestibular Nerve	2014
Pharmacological discrimination of plasmalemmal and mitochondrial sodium-calcium exchanger in cardiomyocyte-derived H9c2 cells. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:1 Topics: Aniline Compounds; Animals; Calcium; Cell Line; Clonazepam; Cytoplasm; Mitochondria, Heart; Myocytes, Cardiac; Phenyl Ethers; Rats; Sodium-Calcium Exchanger; Thiazepines	2015
Benzothiazepine CGP37157 and its 2'-isopropyl analogue modulate Ca²⁺ entry through CALHM1. Neuropharmacology, 2015, Volume: 95 Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cations; Clonazepam; Cobalt; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indoles; Membrane Glycoproteins; Mitochondria; Polymorphism, Genetic; Proton Ionophores; Thiazepines; Transfection	2015
Effects of salinomycin and CGP37157 on head and neck squamous cell carcinoma cell lines in vitro. Molecular medicine reports, 2015, Volume: 12, Issue:3 Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Shape; Clonazepam; Drug Screening Assays, Antitumor; Gene Expression; Head and Neck Neoplasms; Humans; Pyrans; Thiazepines	2015
Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis. Scientific reports, 2016, 06-22, Volume: 6 Topics: Actins; Animals; B-Lymphocytes; Calcium; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis; Clonazepam; Cytosol; Endoplasmic Reticulum; Mice; Mitochondria; Neuropeptides; rac1 GTP-Binding Protein; Sodium-Calcium Exchanger; Spleen; T-Lymphocytes; Thiazepines	2016
Disrupting mitochondrial Ca2+ homeostasis causes tumor-selective TRAIL sensitization through mitochondrial network abnormalities. International journal of oncology, 2017, Volume: 51, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Calcium; Cell Line, Tumor; Clonazepam; Drug Synergism; Homeostasis; Humans; Melanoma; Mitochondria; Neoplasms; Osteosarcoma; Oxidative Phosphorylation; Thiazepines; TNF-Related Apoptosis-Inducing Ligand	2017
KB-R7943 Inhibits the Mitochondrial Ca Biological & pharmaceutical bulletin, 2020, Dec-01, Volume: 43, Issue:12 Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Clonazepam; Mitochondria; Myocytes, Cardiac; Rats; Sodium; Sodium-Calcium Exchanger; Thiazepines; Thiourea	2020