clomipramine and valproic acid

clomipramine has been researched along with valproic acid in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's3 (11.54)18.2507
2000's11 (42.31)29.6817
2010's10 (38.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hwang, EC; Van Woert, MH1
Deltito, JA1
DeToledo, JC; Haddad, H; Ramsay, RE1
Fisman, S; Steele, M1
Dahmen, N; Fehr, C; Gründer, G; Hiemke, C1
Biondi, M; Garavini, A; Pasquini, M1
Aydin, H; Gulcat, Z; Gulsun, M1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S1
Amerio, A; Ghaemi, SN; Marchesi, C; Odone, A1
Nurchi, AM; Pinna, AP; Podda, F; Ripoli, C; Tronci, MG; Zanni, R1

Reviews

2 review(s) available for clomipramine and valproic acid

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for clomipramine and valproic acid

ArticleYear
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007

Other Studies

23 other study(ies) available for clomipramine and valproic acid

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effect of valproic and acid on serotonin metabolism.
    Neuropharmacology, 1979, Volume: 18, Issue:4

    Topics: Animals; Brain; Clomipramine; DDT; History, 18th Century; Hydroxyindoleacetic Acid; Male; Mice; Rats; Serotonin; Tryptophan; Valproic Acid

1979
Valproate pretreatment for the difficult-to-treat patient with OCD.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:11

    Topics: 1-Naphthylamine; Antidepressive Agents; Clomipramine; Drug Therapy, Combination; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Paroxetine; Sertraline; Treatment Outcome; Valproic Acid

1994
Status epilepticus associated with the combination of valproic acid and clomipramine.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:1

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Seizures; Status Epilepticus; Valproic Acid

1997
Bipolar disorder in children and adolescents: current challenges.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1997, Volume: 42, Issue:6

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Clomipramine; Diagnosis, Differential; Female; Humans; Lithium Carbonate; Male; Patient Care Team; Risperidone; Valproic Acid

1997
Increase in serum clomipramine concentrations caused by valproate.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:4

    Topics: Borderline Personality Disorder; Clomipramine; Drug Interactions; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Valproic Acid

2000
Nicotine augmentation for refractory obsessive-compulsive disorder. A case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:1

    Topics: Acetylcholine; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Drug Resistance; GABA Agents; Humans; Male; Nicotine; Nicotinic Agonists; Obsessive-Compulsive Disorder; Valproic Acid

2005
Treatment of compulsive sexual behaviour with clomipramine and valproic acid.
    Clinical drug investigation, 2007, Volume: 27, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Antimanic Agents; Clomipramine; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Female; Follow-Up Studies; Humans; Obsessive-Compulsive Disorder; Sexual Behavior; Treatment Outcome; Turkey; Valproic Acid

2007
Interaction of injectable neurotropic drugs with the red cell membrane.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7

    Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid

2014
Long-term treatment of bipolar disorder: the controversial role of antidepressants.
    The Australian and New Zealand journal of psychiatry, 2014, Volume: 48, Issue:11

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Clomipramine; Humans; Lithium Compounds; Male; Recurrence; Sertraline; Valproic Acid

2014
Second-generation antipsychotic and diabetes mellitus in children and adolescents.
    La Pediatria medica e chirurgica : Medical and surgical pediatrics, 2017, Dec-13, Volume: 39, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Blood Glucose; Clomipramine; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Lithium; Male; Metformin; Olanzapine; Valproic Acid

2017