clomipramine and naloxone

clomipramine has been researched along with naloxone in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19909 (30.00)18.7374
1990's6 (20.00)18.2507
2000's7 (23.33)29.6817
2010's8 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Eto, Y; Kusano, K; Okazaki, M; Sugama, S1
Molina, VA; Murua, VS1
Ardid, D; Eschalier, A; Lavarenne, J1
Ansuategui, M; Feria, M; Naharro, L1
Garcia, MC; Kenney, RM; McDonnell, SM1
Bastide, P; Eschalier, A; Fialip, J; Makambila, MC; Marty, H; Varoquaux, O1
Goodlet, I; Sugrue, MF1
Hagan, RM; Hughes, IE1
Evans, G; Groom, GV1
Devoize, JL; Eschalier, A; Gaillard-Plaza, G; Montastruc, JL; Pechadre, JC; Rigal, F1
Devoize, JL; Eschalier, A; Rigal, F; Trolese, JF1
Groom, GV; Huws, D1
Bastide, P; Coudert, P; Rubat, C; Tronche, P1
Hagan, MM; Moss, DE1
Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F1
Alloui, A; Ardid, D; Chapuy, E; Eschalier, A; Jourdan, D; Marchand, F1
Chen, JY; Chen, YA; Tao, PL; Wu, CC; Yeh, GC1
Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS1
Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Yamada, T1

Reviews

2 review(s) available for clomipramine and naloxone

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for clomipramine and naloxone

ArticleYear
The effect of naloxone on psychotropic drug-induced prolactin, growth hormone and cortisol secretion--a preliminary report.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 1

    Topics: Adult; Clomipramine; Drug Interactions; Female; Growth Hormone; Humans; Hydrocortisone; Male; Naloxone; Prolactin; Psychotropic Drugs; Time Factors

1980

Other Studies

27 other study(ies) available for clomipramine and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[The neuroendocrinological examinations in mentally retarded boy with self-injurious behavior (SIB) and the effect of naloxone, clomipramine and sulpiride on SIB].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:8

    Topics: Child; Clomipramine; Humans; Intellectual Disability; Male; Naloxone; Pituitary Function Tests; Self-Injurious Behavior; Sulpiride

1992
Chronic antidepressant counteracts the conditioned analgesia induced by a context previously associated with inescapable shock.
    Psychopharmacology, 1991, Volume: 105, Issue:3

    Topics: Analgesia; Animals; Antidepressive Agents; Clomipramine; Conditioning, Classical; Desipramine; Electroshock; Male; Naloxone; Phenelzine; Rats; Rats, Inbred Strains; Reaction Time

1991
Evidence for a central but not a peripheral analgesic effect of clomipramine in rats.
    Pain, 1991, Volume: 45, Issue:1

    Topics: Analgesics; Animals; Central Nervous System; Clomipramine; Edema; Foot; Injections; Injections, Intravenous; Male; Naloxone; Pain; Peripheral Nerves; Rats; Rats, Inbred Strains; Sensory Thresholds

1991
Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats.
    Psychopharmacology, 1989, Volume: 98, Issue:1

    Topics: Analgesics; Animals; Clomipramine; Endorphins; Female; Formaldehyde; Morphine; Naloxone; Norepinephrine; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine

1989
Pharmacological manipulation of sexual behaviour in stallions.
    Journal of reproduction and fertility. Supplement, 1987, Volume: 35

    Topics: Animals; Clomipramine; Diazepam; Ejaculation; Fenclonine; Horses; Imipramine; Male; Naloxone; Penile Erection; Pituitary Hormone-Releasing Hormones; Sexual Behavior, Animal; Yohimbine

1987
Pharmacokinetic patterns of repeated administration of antidepressants in animals. I. Implications for antinociceptive action of clomipramine in mice.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Analgesics; Animals; Clomipramine; Male; Mice; Motor Activity; Naloxone; Species Specificity

1988
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan

1974
Opioid receptor sub-types involved in the control of transmitter release in cortex of the brain of the rat.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Animals; beta-Lipotropin; Cerebral Cortex; Clomipramine; Edetic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Estradiol; In Vitro Techniques; Male; Morphine; Morphine Derivatives; Naloxone; Narcotics; Neurotransmitter Agents; Norepinephrine; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin

1984
The interrelationship between hormones, psychotropic drugs and the opiate receptor--a pilot study.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 1

    Topics: Animals; Clomipramine; Corticosterone; Endorphins; Gonadotropins, Pituitary; Luteinizing Hormone; Male; Morphine; Naloxone; Organ Culture Techniques; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Opioid

1980
Influence of naloxone and methysergide on the analgesic effect of clomipramine in rats.
    European journal of pharmacology, 1981, Aug-27, Volume: 74, Issue:1

    Topics: Analgesics; Animals; Clomipramine; Male; Methysergide; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Serotonin

1981
Naloxone inhibits clomipramine in mouse forced swimming test.
    European journal of pharmacology, 1982, Feb-26, Volume: 78, Issue:2

    Topics: Animals; Clomipramine; Escape Reaction; Male; Mice; Naloxone; Physical Exertion; Swimming

1982
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine

1995
Effect of naloxone and antidepressants on hyperphagia produced by peptide YY.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Antidepressive Agents; Clomipramine; Dose-Response Relationship, Drug; Feeding Behavior; Female; Fluoxetine; Gastrointestinal Hormones; Injections, Intraperitoneal; Injections, Intraventricular; Naloxone; Peptide YY; Peptides; Rats; Rats, Sprague-Dawley

1993
Interaction of opioids with antidepressant-induced antinociception.
    Psychopharmacology, 1995, Volume: 122, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine

1995
Evidence for an involvement of supraspinal delta- and spinal mu-opioid receptors in the antihyperalgesic effect of chronically administered clomipramine in mononeuropathic rats.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Animals; Clomipramine; Dose-Response Relationship, Drug; Drug Interactions; Hyperalgesia; Male; Mononeuropathies; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Spinal Cord

2003
Serotonin reuptake inhibitors attenuate morphine withdrawal syndrome in neonatal rats passively exposed to morphine.
    European journal of pharmacology, 2005, Apr-04, Volume: 512, Issue:1

    Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Clomipramine; Female; Fluoxetine; Maternal-Fetal Exchange; Morphine Dependence; Naloxone; Narcotic Antagonists; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome

2005
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
    British journal of pharmacology, 2011, Volume: 163, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes

2011
Relationship between noradrenaline release in the locus coeruleus and antiallodynic efficacy of analgesics in rats with painful diabetic neuropathy.
    Life sciences, 2013, Jun-21, Volume: 92, Issue:23

    Topics: Adrenergic Neurons; Analgesics; Animals; Clomipramine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Female; Hyperalgesia; Locus Coeruleus; Morphine; Naloxone; Norepinephrine; Rats; Rats, Sprague-Dawley; Tramadol

2013