clomipramine and clozapine

clomipramine has been researched along with clozapine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.63)	18.7374
1990's	6 (15.79)	18.2507
2000's	16 (42.11)	29.6817
2010's	15 (39.47)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chiang, GH; Unger, SH	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Hajjo, R; Roth, BL; Setola, V; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Greenblatt, DJ; Shader, RI	1
Goodman, WK; McDougle, CJ; Price, LH	1
Folstein, MF; Holzer, JC; Jacobson, SA	1
Hedenmalm, K; Spigset, O	1
Altamura, AC; Bignotti, S; Curreli, R; Pioli, R; Tura, G	1
Dewan, V; Zerjav-Lacombe, S	1
Biondi, L; Cassano, GB; Ciapparelli, A; Dell'Osso, L; Giannaccini, G; Giromella, A; Marazziti, D; Palego, L; Sarno, N	1
Cheung, EF	1
Dawson, A; Isbister, GK; Whtye, IM; Whyte, IM	1
Christodoulou, GN; Hatzimanolis, J; Lykouras, L; Markianos, M	1
Bernardi, S; Meco, G	1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J	1
Amato, D; Borsini, F; Nencini, P; Stasi, MA	1
Aukst-Margetić, B; Jakovljević, M; Margetić, B	1
Baeza, I; Castro-Fornieles, J; Horga, A; Horga, G; Lázaro, L; Pons, A	1
Barros, S; de Carvalho, J	1
Andrade, C	1

Reviews

3 review(s) available for clomipramine and clozapine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder. The Journal of clinical psychiatry, 1994, Volume: 55 Suppl Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists; Drug Therapy, Combination; Female; Fluvoxamine; Haloperidol; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Tic Disorders; Tourette Syndrome	1994
Pathological gambling and primary antiphospholipid (Hughes) syndrome: a unique neuropsychiatric association. Lupus, 2011, Volume: 20, Issue:10 Topics: Antidepressive Agents; Antiphospholipid Syndrome; Antipsychotic Agents; Clomipramine; Clozapine; Fluoxetine; Fructose; Gambling; Humans; Male; Middle Aged; Topiramate	2011

Trials

1 trial(s) available for clomipramine and clozapine

Article	Year
Motor cortex excitability after vagus nerve stimulation in major depression. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2 Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid	2007

Article

Year

Motor cortex excitability after vagus nerve stimulation in major depression.

Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007

Other Studies

34 other study(ies) available for clomipramine and clozapine

Article	Year
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship	1981
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers. Journal of medicinal chemistry, 2012, Jun-28, Volume: 55, Issue:12 Topics: Alzheimer Disease; Cell Line, Tumor; Cloning, Molecular; Cognition; Drug Discovery; Drug Evaluation, Preclinical; Genomics; Humans; Informatics; Ligands; Nootropic Agents; Quantitative Structure-Activity Relationship; Raloxifene Hydrochloride; Receptors, Serotonin; Reproducibility of Results; Selective Estrogen Receptor Modulators; Serotonin Antagonists; User-Computer Interface	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Newly marketed medications: ABCs and mind your Qs. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2 Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Bupropion; Clomipramine; Clozapine; Humans; Propiophenones	1990
Understanding and treating psychoses: advances in research and therapy. The Journal of clinical psychiatry, 1993, Volume: 54, Issue:11 Topics: Antipsychotic Agents; Clomipramine; Clozapine; Family; Humans; Receptors, Dopamine; Receptors, Serotonin; Risk Factors; Schizophrenia	1993
Treating compulsive self-mutilation in a mentally retarded patient. The American journal of psychiatry, 1996, Volume: 153, Issue:1 Topics: Clomipramine; Clozapine; Compulsive Behavior; Drug Administration Schedule; Drug Therapy, Combination; Humans; Intellectual Disability; Male; Middle Aged; Self Mutilation; Treatment Outcome	1996
Hyponatremia during treatment with clomipramine, perphenazine, or clozapine: study of therapeutic drug monitoring samples. Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:5 Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Drug Monitoring; Electrolytes; Female; Humans; Hyponatremia; Male; Perphenazine	1996
Depressive symptomatology during clozapine treatment: two case reports. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1998, Volume: 8, Issue:3 Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Depression; Female; Humans; Male; Middle Aged; Paroxetine; Schizophrenia	1998
Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:2 Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia; Serotonin Syndrome; Substance Withdrawal Syndrome	2001
Simultaneous analysis of clozapine, clomipramine and their metabolites by reversed-phase liquid chromatography. Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:3 Topics: Antidepressive Agents, Tricyclic; Chromatography, Liquid; Clomipramine; Clozapine; Female; Humans; Least-Squares Analysis; Linear Models; Male	2001
Obsessive-compulsive symptoms during treatment with clozapine in a patient with schizophrenia. The Australian and New Zealand journal of psychiatry, 2001, Volume: 35, Issue:5 Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Clozapine; Drug Therapy, Combination; Female; Humans; Obsessive-Compulsive Disorder; Schizophrenia, Disorganized; Treatment Outcome	2001
Comment: serotonin syndrome and 5-HT2A antagonism. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:9 Topics: Animals; Clomipramine; Clozapine; Humans; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome; Substance Withdrawal Syndrome	2001
Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapine. Schizophrenia research, 2002, Jul-01, Volume: 56, Issue:1-2 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clomipramine; Clozapine; Haloperidol; Humans; Hypothalamo-Hypophyseal System; Male; Middle Aged; Olanzapine; Pirenzepine; Prolactin; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Serotonin; Schizophrenia; Treatment Outcome	2002
Antidepressant use in treatment of psychosis with comorbid depression in Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1 Topics: Affect; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Antipsychotic Agents; Clomipramine; Clozapine; Delusions; Depressive Disorder; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pergolide; Psychiatric Status Rating Scales; Psychotic Disorders	2007
Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia. Psychopharmacology, 2008, Volume: 200, Issue:2 Topics: Administration, Oral; Animals; Antipsychotic Agents; Benzodiazepines; Clomipramine; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Haloperidol; Male; Olanzapine; Piperazines; Pyrroles; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Thiazepines	2008
Aggravation of schizophrenia by clomipramine in a patient with comorbid obsessive-compulsive disorder. Psychopharmacology bulletin, 2008, Volume: 41, Issue:2 Topics: Antidepressive Agents, Tricyclic; Clomipramine; Clozapine; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Schizophrenia	2008
Drug-induced speech dysfluency and myoclonus preceding generalized tonic-clonic seizures in an adolescent male with schizophrenia. Journal of child and adolescent psychopharmacology, 2010, Volume: 20, Issue:3 Topics: Adolescent; Antipsychotic Agents; Clomipramine; Clozapine; Epilepsy, Tonic-Clonic; Humans; Male; Myoclonus; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Stuttering	2010
Serotonin reuptake inhibitor treatment of obsessive-compulsive symptoms in clozapine-medicated schizophrenia. The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11 Topics: Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Clomipramine; Clozapine; Comorbidity; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia; Selective Serotonin Reuptake Inhibitors	2012