clofilium has been researched along with uk 68798 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G | 1 |
| Chi, L; Friedrichs, GS; Green, AL; Lucchesi, BR | 1 |
| Bursill, JA; Campbell, TJ; Wyse, KR | 1 |
| Brasington, CR; Case, CL; Hewett, KW; Le, FK; Martin, KL; Piecuch, S | 1 |
| Al-Khalidi, H; Brooks, RR; Drexler, AP; Kostreva, DR; Maynard, AE | 1 |
| Finlayson, K; Kelly, JS; Pennington, AJ | 1 |
| Finlayson, K; January, CT; Kelly, JS; Sharkey, J; Turnbull, L | 1 |
| de Groot, MJ; Helliwell, R; Leishman, D; Mitcheson, J; Perry, M; Sanguinetti, MC; Tristani-Firouzi, M | 1 |
| Beatch, GN; Ezrin, AM; Fedida, D; Hesketh, JC; Lin, S; Mak, CK; Orth, PM; Yang, Y | 1 |
| Hamlin, RL; Keene, BW; Kijtawornrat, A; Nishijima, Y; Roche, BM | 1 |
11 other study(ies) available for clofilium and uk 68798
| Article | Year |
|---|---|
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes | 1993 |
Antifibrillatory effects of clofilium in the rabbit isolated heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Decanoic Acids; Disease Models, Animal; Glyburide; Heart; Hydroxy Acids; In Vitro Techniques; Myocardium; Oxygen Consumption; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Quaternary Ammonium Compounds; Rabbits; Refractory Period, Electrophysiological; Sulfonamides; Ventricular Fibrillation; Ventricular Pressure | 1994 |
Differential effects of antiarrhythmic agents on post-pause repolarization in cardiac Purkinje fibres.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Phenethylamines; Potassium Channels; Purkinje Fibers; Quaternary Ammonium Compounds; Quinidine; Sodium Channels; Sotalol; Sulfonamides | 1996 |
Changes in atrioventricular conduction properties with refractory-period modulation.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bundle of His; Electrophysiology; Heart Conduction System; Phenethylamines; Purkinje Fibers; Quaternary Ammonium Compounds; Rabbits; Sulfanilamides; Sulfonamides | 1996 |
Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Male; Methoxamine; Phenethylamines; Piperazines; Procainamide; Quaternary Ammonium Compounds; Rabbits; Sotalol; Sulfonamides | 2000 |
[3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel?
Topics: Animals; Anti-Arrhythmia Agents; Benzimidazoles; Binding Sites; Cation Transport Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Quaternary Ammonium Compounds; Radioligand Assay; RNA; Sulfanilamides; Sulfonamides; Trans-Activators; Transcriptional Regulator ERG; Tumor Cells, Cultured | 2001 |
[3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen.
Topics: Anti-Arrhythmia Agents; Benzimidazoles; Binding, Competitive; Cation Transport Proteins; Cell Line; Cell Membrane; DNA-Binding Proteins; Drug Evaluation, Preclinical; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Haloperidol; Humans; Patch-Clamp Techniques; Phenethylamines; Pimozide; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Sulfanilamides; Sulfonamides; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Transfection; Tritium | 2001 |
Structural determinants of HERG channel block by clofilium and ibutilide.
Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Aspartic Acid; Benzopyrans; Binding Sites; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Phenethylamines; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Quaternary Ammonium Compounds; Serine; Sulfonamides; Tyrosine; Xenopus laevis | 2004 |
RSD1235 blocks late INa and suppresses early afterdepolarizations and torsades de pointes induced by class III agents.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Dose-Response Relationship, Drug; Female; Membrane Transport Modulators; Models, Animal; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Purkinje Fibers; Quaternary Ammonium Compounds; Rabbits; Sodium Channel Blockers; Sulfonamides; Torsades de Pointes | 2006 |
Use of a failing rabbit heart as a model to predict torsadogenicity.
Topics: Amiodarone; Animals; Cardiac Output, Low; Cisapride; Dose-Response Relationship, Drug; Electrocardiography; Models, Animal; Phenethylamines; Quaternary Ammonium Compounds; Quinidine; Rabbits; Sulfonamides; Torsades de Pointes; Verapamil | 2006 |