clofibric acid and simvastatin

clofibric acid has been researched along with simvastatin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (45.45)18.2507
2000's11 (50.00)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Infante, J; Infante, R; Qin, W; Wang, SR1
Charmoillaux, M; Goudonnet, H; Mercenne, F; Mounié, J; Truchot, RC1
Devuyst, O; Goffin, E; Pirson, Y; van Ypersele de Strihou, C1
Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W1
Athyros, VG; Boudoulas, H; Hatzikonstandinou, HA; Kontopoulos, AG; Mayroudi, MC; Papageorgiou, AA1
Autier, P; Muls, E; Van Gaal, L; Vansant, G1
Athyros, VG; Carina, MV; Didangelos, TP; Hatzikonstandinou, HA; Kontopoulos, AG; Kranitsas, DF; Papageorgiou, AA1
Bruckert, E1
Kvetnoi, IM; Martinsen, TC; Sandvik, AK; Schulze, B; Sylte, R; Waldum, HL1
Sinzinger, H1
Athyros, VG; Kontopoulos, AG; Papageorgiou, AA1
Athyros, VG; Athyrou, VV; Demitriadis, DS; Kontopoulos, AG; Papageorgiou, AA; Pehlivanidis, AN1
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D1
Romaniv, S; Vecka, M; Zák, A; Zeman, M1
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A1
Balcerak, M; Broncel, M; Chojnowska-Jezierska, J1
DeLorenzo, ME; Fleming, J1
Doggrell, SA1
Kaye, T1
Chan, SY; Frohlich, J; Ignaszewski, A; Mancini, GB1
Hausenloy, DJ; Yellon, DM1
Briel, M; Ferreira-González, I; Jakob, T; Nordmann, AJ; Schandelmaier, S1

Reviews

6 review(s) available for clofibric acid and simvastatin

ArticleYear
[Treatment of familial combined hyperlipidemia].
    Annales d'endocrinologie, 1997, Volume: 58, Issue:4

    Topics: Clinical Protocols; Clofibric Acid; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Nicotinic Acids; Simvastatin

1997
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38

    Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis

1998
[Influence of combined, hypolipemic therapy on lipids and non-lipid atherosclerosis risk factors].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 22, Issue:127

    Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Drug Therapy, Combination; Ezetimibe; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Niacin; Risk Factors; Simvastatin

2007
Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:2

    Topics: Amlodipine; Anticholesteremic Agents; Atorvastatin; Azetidines; Cardiovascular Diseases; Clinical Trials as Topic; Clofibric Acid; Ezetimibe; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Indoles; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2006
Enhancing cardiovascular disease risk reduction: raising high-density lipoprotein levels.
    Current opinion in cardiology, 2009, Volume: 24, Issue:5

    Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Disease Progression; Drug Therapy, Combination; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Risk Factors; Risk Reduction Behavior; Simvastatin; United Kingdom

2009
Fibrates for primary prevention of cardiovascular disease events.
    The Cochrane database of systematic reviews, 2016, 11-16, Volume: 11

    Topics: Atorvastatin; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Middle Aged; Myocardial Infarction; Primary Prevention; Simvastatin; Stroke

2016

Trials

7 trial(s) available for clofibric acid and simvastatin

ArticleYear
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1995
Effects of simvastatin and ciprofibrate alone and in combination on lipid profile, plasma fibrinogen and low density lipoprotein particle structure and distribution in patients with familial combined hyperlipidaemia and coronary artery disease.
    Coronary artery disease, 1996, Volume: 7, Issue:11

    Topics: Adult; Analysis of Variance; Clofibric Acid; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Fibric Acids; Fibrinogen; Follow-Up Studies; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Morbidity; Prospective Studies; Safety; Simvastatin; Survival Rate; Treatment Outcome; Ultracentrifugation

1996
Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia.
    The American journal of cardiology, 1997, Sep-01, Volume: 80, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol, LDL; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome

1997
Statin-fibrate combinations in patients with combined hyperlipedemia.
    Atherosclerosis, 2001, Volume: 155, Issue:1

    Topics: Clofibric Acid; Coronary Disease; Drug Therapy, Combination; Fibric Acids; Follow-Up Studies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Myocardial Infarction; Pravastatin; Simvastatin; Stroke

2001
Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia.
    Journal of cardiovascular risk, 2002, Volume: 9, Issue:1

    Topics: Adult; Aged; Atorvastatin; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Time Factors

2002
[Long-term hypolipidemic treatment of mixed hyperlipidemia with a combination of statins and fibrates].
    Casopis lekaru ceskych, 2003, Volume: 142, Issue:8

    Topics: Adult; Aged; Anticholesteremic Agents; Clofibric Acid; Drug Therapy, Combination; Female; Fenofibrate; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Simvastatin

2003
Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study.
    BMC clinical pharmacology, 2008, Oct-28, Volume: 8

    Topics: Aged; Clofibric Acid; Cross-Over Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Male; Middle Aged; Nuclear Magnetic Resonance, Biomolecular; Particle Size; Placebos; Prospective Studies; Simvastatin

2008

Other Studies

9 other study(ies) available for clofibric acid and simvastatin

ArticleYear
Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
    Biochimica et biophysica acta, 1992, Jul-09, Volume: 1127, Issue:1

    Topics: Acetates; Animals; Anticholesteremic Agents; Apolipoproteins B; Cell Line; Cholesterol; Clofibric Acid; Dose-Response Relationship, Drug; Fibric Acids; Gene Expression Regulation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Liver; Lovastatin; Mevalonic Acid; Rats; Receptors, LDL; RNA, Messenger; Simvastatin

1992
Comparative and simultaneous effects of simvastatin and ciprofibrate on plasma lipid parameters and upon hepatic drug metabolizing and peroxisome proliferation marker enzymes in the male Wistar rat.
    Cellular and molecular biology, 1991, Volume: 37, Issue:8

    Topics: Animals; Anticholesteremic Agents; Clofibric Acid; Fibric Acids; Hypolipidemic Agents; Lipids; Liver; Lovastatin; Male; Microbodies; Mixed Function Oxygenases; Rats; Simvastatin

1991
Hypercholesterolemia treatment in a renal transplant patient.
    Clinical nephrology, 1994, Volume: 41, Issue:5

    Topics: Anticholesteremic Agents; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Postoperative Complications; Simvastatin

1994
Effects of initial BMI and on-treatment weight change on the lipid-lowering efficacy of fibrates.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21, Issue:2

    Topics: Body Mass Index; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Prospective Studies; Sex Factors; Simvastatin; Weight Loss

1997
The effect of the peroxisome proliferator ciprofibrate on the gastric mucosa and particularly the gastrin cell.
    Journal of molecular endocrinology, 1998, Volume: 20, Issue:1

    Topics: Animals; Anticholesteremic Agents; Clofibric Acid; Female; Fibric Acids; Gastric Mucosa; Gastrins; Gene Expression; Histidine Decarboxylase; Hypolipidemic Agents; Lovastatin; Male; Microbodies; Rats; Rats, Inbred F344; Rats, Wistar; Simvastatin; Somatostatin; Species Specificity

1998
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured

2003
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
    American journal of hypertension, 2005, Volume: 18, Issue:11

    Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2005
Individual and mixture effects of selected pharmaceuticals and personal care products on the marine phytoplankton species Dunaliella tertiolecta.
    Archives of environmental contamination and toxicology, 2008, Volume: 54, Issue:2

    Topics: Carbamazepine; Chlorophyta; Clofibric Acid; Diclofenac; Drug Interactions; Fluoxetine; Household Products; Phytoplankton; Simvastatin; Triclosan; Water Pollutants, Chemical

2008
Simvastatin with or without ezetimibe in familial hypercholesterolemia.
    The New England journal of medicine, 2008, Jul-31, Volume: 359, Issue:5

    Topics: Anticholesteremic Agents; Azetidines; Clofibric Acid; Drug Therapy, Combination; Ezetimibe; Humans; Hyperlipoproteinemia Type II; Niacin; Simvastatin

2008