clofibrate and tryptophan

clofibrate has been researched along with tryptophan in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's4 (18.18)18.2507
2000's5 (22.73)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Coppen, A; Wood, K2
Collu, R; Letarte, J; Tache, Y1
Paoletti, R; Sirtori, C; Spano, PF1
Fumagalli, R; Sirtori, CR; Torreggiani, D1
Bittard, M1
Edwards, KD; Neale, FC; Schapel, GJ1
Galli, CL; Ricci, A; Spano, PF; Szyszka, K1
Edwards, KD1
Pozza, G; Sirtori, CR; Spano, PF; Szyszka, K1
Curzon, G1
Bloxam, DL; Curzon, G; Patel, AJ; Tricklebank, MD1
Fujita, Y; Kimura, A; Mori, Y; Sano, K; Shin, M; Umezawa, C; Yoshida, K1
Kondo, T; Marugami, M; Shibata, K; Umezawa, C1
Hashimoto, C; Nakakita, S; Sano, K; Shin, M; Umezawa, C1
Sano, K; Shin, M; Umezawa, C1
Ohnishi, M; Sano, K; Shin, M; Umezawa, C1
Egashira, Y; Sanada, H; Sato, M; Shin, M; Sugawara, R; Tanabe, A1

Reviews

5 review(s) available for clofibrate and tryptophan

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Clinical relevance of drugs affecting tryptophan transport.
    Annual review of pharmacology, 1975, Volume: 15

    Topics: Anti-Inflammatory Agents; Biological Transport; Clofibrate; Contraceptives, Oral; Female; Humans; Probenecid; Time Factors; Tryptophan

1975
Mechanism of action of hypolipidemic drugs.
    Advances in experimental medicine and biology, 1975, Volume: 63

    Topics: Acetoacetates; Animals; Brain; Cholesterol; Clofibrate; Colestipol; Ethanol; Humans; Hydroxybutyrates; Hydroxyindoleacetic Acid; Hyperlipidemias; Liver; Nerve Tissue Proteins; Polyamines; Rats; Triglycerides; Tryptophan

1975
[Prognosis of primary tumors of the bladder].
    Journal d'urologie, 1985, Volume: 91, Issue:6

    Topics: Aged; Alkylating Agents; Amines; Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Clofibrate; Epithelium; Female; France; Humans; Hyperplasia; Male; Middle Aged; Nitrosamines; Occupational Diseases; Occupational Medicine; Prognosis; Retinoids; Saccharin; Schistosomiasis haematobia; Tryptophan; Urinary Bladder Neoplasms; Workers' Compensation

1985
Antilipaemic drugs and nephrotic hyperlipidaemia.
    Progress in biochemical pharmacology, 1972, Volume: 7

    Topics: Alkenes; Animals; Blood Protein Disorders; Blood Proteins; Butyrates; Clofibrate; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipoproteins; Nephrotic Syndrome; Phospholipids; Thyroxine; Tryptophan

1972

Trials

2 trial(s) available for clofibrate and tryptophan

ArticleYear
Tryptophan and depressive illness.
    Psychological medicine, 1978, Volume: 8, Issue:1

    Topics: Blood Proteins; Clinical Trials as Topic; Clofibrate; Depression; Dietary Proteins; Double-Blind Method; Estrogens, Conjugated (USP); Fatty Acids, Nonesterified; Female; Humans; Menopause; Middle Aged; Protein Binding; Tryptophan

1978
Influence of clofibrate on serum tryptophan in man.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Jul-04, Volume: 163, Issue:3

    Topics: Brain; Circadian Rhythm; Clofibrate; Humans; Hydroxyindoleacetic Acid; Placebos; Protein Binding; Serotonin; Time Factors; Tryptophan

1974

Other Studies

15 other study(ies) available for clofibrate and tryptophan

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of clofibrate on plasma tryptophan, growth hormone, and prolactin and on brain tryptophan and serotonin in prepubertal rats.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:2

    Topics: Animals; Brain Chemistry; Clofibrate; Fatty Acids, Nonesterified; Growth; Growth Hormone; Male; Prolactin; Rats; Serotonin; Sexual Maturation; Time Factors; Triglycerides; Tryptophan

1978
The effect of clofibrate on total and free plasma tryptophan in depressed patients.
    Neuropharmacology, 1978, Volume: 17, Issue:6

    Topics: Blood Proteins; Clofibrate; Depression; Fatty Acids, Nonesterified; Female; Humans; Male; Protein Binding; Serum Albumin; Time Factors; Tryptophan

1978
Factorial study of the efficacy of cholestyramine, L-tryptophan and clofibrate in human nephrotic hyperlipidaemia.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Adolescent; Adult; Alkenes; Blood Pressure; Butyrates; Cholesterol; Cholestyramine Resin; Clofibrate; Creatine Kinase; Creatinine; Female; Fluorometry; Hemoglobins; Humans; Hyperlipidemias; L-Lactate Dehydrogenase; Male; Middle Aged; Nephrotic Syndrome; Serum Albumin; Triglycerides; Tryptophan; Urate Oxidase

1974
Effect of clofibrate on free and total tryptophan in serum and brain tryptophan metabolism.
    Pharmacological research communications, 1974, Volume: 6, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Clofibrate; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Rats; Serotonin; Time Factors; Tryptophan; Ultrafiltration

1974
Influence of plasma tryptophan on brain 5HT synthesis and serotonergic activity.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Amino Acids; Animals; Biological Transport; Blood-Brain Barrier; Brain; Cerebral Cortex; Clofibrate; Humans; Kinetics; Rats; Serotonin; Serum Albumin, Bovine; Stress, Physiological; Tryptophan

1981
Effects of albumin, amino acids, and clofibrate on the uptake of tryptophan by the rat brain.
    Journal of neurochemistry, 1980, Volume: 34, Issue:1

    Topics: Amino Acids; Animals; Biological Transport; Blood-Brain Barrier; Brain; Clofibrate; Kinetics; Male; Organ Specificity; Rats; Serum Albumin, Bovine; Tryptophan

1980
NAD+ biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Animals; Cells, Cultured; Clofibrate; Diet; Liver; Male; NAD; Niacin; Pentosyltransferases; Rats; Rats, Sprague-Dawley; Tryptophan

1996
Increased conversion ratio of tryptophan to niacin by the administration of clofibrate, a hypolipidemic drug, to rats.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:9

    Topics: Animals; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain

1996
NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes--effect of clofibrate-feeding.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1998, Volume: 68, Issue:2

    Topics: Animals; Biological Transport; Clofibrate; Glutarates; Hydrolases; Liver; Male; Microbodies; NAD; Niacin; Rats; Rats, Sprague-Dawley; Tryptophan

1998
Effects of peroxisome-proliferators on the TRP-NAD pathway.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Animals; Carboxy-Lyases; Cells, Cultured; Clofibrate; Female; Liver; Male; NAD; NADP; Niacin; Oxidation-Reduction; Pentosyltransferases; Peroxisome Proliferators; Peroxisomes; Phenothiazines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan

1999
NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Cells, Cultured; Clofibrate; Hepatocytes; NAD; Peroxisome Proliferators; Rats; Tryptophan

2003
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2006, Volume: 76, Issue:3

    Topics: Analysis of Variance; Animals; Antitubercular Agents; Carboxy-Lyases; Clofibrate; Diet, Fat-Restricted; Diet, Protein-Restricted; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Kidney; Liver; Male; Models, Animal; NAD; Peroxisome Proliferators; Pyrazinamide; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Tryptophan; Weight Gain

2006