clofibrate has been researched along with tretinoin in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aldridge, TC; Green, S; Issemann, I; Prince, RA; Tugwood, JD | 1 |
| Chawla, A; Lazar, MA | 1 |
| Barlow, JW; Crowe, TC; Loidl, NM; Payne, KL; Stockigt, JR; Topliss, DJ | 1 |
| Byers, DM; Cook, HW; Mandla, SG; Ridgway, ND | 1 |
| Authier, F; Cameron, PH; Taupin, V | 1 |
| Crabb, D; Dorris, R; Galli, A; Stewart, M | 1 |
| Higa, M; Lee, Y; Milburn, JL; Newgard, CB; Shimabukuro, M; Unger, RH; Wang, MY; Zhou, YT | 1 |
| Kockx, M; Kooistra, T; Princen, HM | 1 |
| Grott, S; Kutz, S; Radtke, C; Seitz, HJ; Weitzel, JM | 1 |
| Hannaert, JC; Hellemans, K; Kerckhofs, K; Martens, G; Pipeleers, D; Van Veldhoven, P | 1 |
3 review(s) available for clofibrate and tretinoin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Delineating peroxisome proliferator action to improve human risk assessment.
Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Clofibrate; Cloning, Molecular; Diethylhexyl Phthalate; DNA; Fatty Acids; Humans; Liver; Liver Neoplasms, Experimental; Mice; Microbodies; Molecular Sequence Data; Oxidoreductases; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Assessment; Transcription Factors; Tretinoin | 1994 |
16 other study(ies) available for clofibrate and tretinoin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival.
Topics: 3T3 Cells; 5,8,11,14-Eicosatetraynoic Acid; Adipose Tissue; Animals; Apoptosis; Cell Survival; Clofibrate; Culture Media; Mice; Microbodies; Phenotype; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Stem Cells; Transcription Factors; Tretinoin | 1994 |
Differential modulation of thyroid hormone responsiveness by retinoids in a human cell line.
Topics: Carcinoma, Hepatocellular; Clofibrate; Dose-Response Relationship, Drug; Humans; Sex Hormone-Binding Globulin; Stereoisomerism; Thyroxine-Binding Proteins; Tretinoin; Triiodothyronine; Tumor Cells, Cultured; Vitamin D | 1996 |
Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Clofibrate; Enzyme Inhibitors; Ethanolamine; Ethanolamines; Fibroblasts; Humans; Hypolipidemic Agents; Isoquinolines; Phosphatidylcholines; Phospholipids; Protein Kinase C; Skin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1996 |
Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells.
Topics: Animals; Blotting, Northern; Carcinoma, Hepatocellular; Cells, Cultured; CHO Cells; Clofibrate; Cricetinae; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Insulysin; Microbodies; Molecular Weight; Neoplasm Proteins; RNA, Messenger; Subcellular Fractions; Transfection; Tretinoin | 1996 |
High-level expression of RXRalpha and the presence of endogenous ligands contribute to expression of a peroxisome proliferator-activated receptor-responsive gene in hepatoma cells.
Topics: Carcinoma, Hepatocellular; Clofibrate; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Liver; Luciferases; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1998 |
Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.
Topics: Animals; Base Sequence; Clofibrate; DNA Primers; Gene Expression Regulation; Islets of Langerhans; Leptin; Male; Pancreatic Diseases; Proteins; Rats; Rats, Mutant Strains; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tretinoin | 1998 |
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin | 1998 |
Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene: identification of a complex hormone-response element in the ubiquitous promoter B.
Topics: Animals; Base Sequence; Clofibrate; Gene Expression Regulation, Enzymologic; Glycerolphosphate Dehydrogenase; Hormones; Humans; Mitochondria; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Receptors, Thyroid Hormone; Response Elements; Steroids; Tretinoin; Triiodothyronine | 2001 |
Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.
Topics: Alitretinoin; Animals; Carbon Radioisotopes; Carnitine; Cell Death; Cell Survival; Cells, Cultured; Clofibrate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoxy Compounds; Gene Expression; Glucose; Insulin-Secreting Cells; Kinetics; Male; Mitochondria; Oxidation-Reduction; Palmitates; PPAR alpha; Protective Agents; Rats; Rats, Wistar; Retinoid X Receptors; RNA, Messenger; Tretinoin | 2007 |