clofibrate and theophylline

clofibrate has been researched along with theophylline in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's1 (4.55)18.2507
2000's2 (9.09)29.6817
2010's9 (40.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Raheja, KL; Tepperman, HM; Tepperman, J1
Ditschuneit, H; Ditschuneit, HH; Fussgänger, R1
Carlson, LA1
Blaton, V; Ferenczi, M; Lambelin, G; Peeters, H; Roba, J; Roncucci, R; Vandamme, D1
Diamantini, G; Duranti, E; Pescador, R; Salvatori, A; Spadoni, G1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M1
Bachmann, KA; Jahn, D; Schwartz, J; Yang, C1
Mendoza, SA; Tarpey, GM1
Farkas, K; Kusztos, D; Németh-Csóka, M; Pados, G; Valyon, M1
Djaja, S; Machalke, K; Richter, E1
Da Re, P; Gaion, RM; Montanari, P; Valenti, P1

Reviews

2 review(s) available for clofibrate and theophylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The effect of drugs on bile flow and composition. An overview.
    Drugs, 1986, Volume: 31, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid

1986

Trials

1 trial(s) available for clofibrate and theophylline

ArticleYear
[Lipid-lowering effect of etofibrate, bezafibrate and xanthinol nicotinate in patients with hyperlipoproteinemias].
    Therapie der Gegenwart, 1982, Volume: 121, Issue:5

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Theophylline; Xanthinol Niacinate

1982

Other Studies

19 other study(ies) available for clofibrate and theophylline

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of oral clofibrate administration on intestinal 3-O-methyl glucose absorption in rat and chick.
    General pharmacology, 1978, Volume: 9, Issue:2

    Topics: Animals; Blood Glucose; Bucladesine; Chickens; Cholesterol; Clofibrate; In Vitro Techniques; Insulin; Intestinal Absorption; Male; Methylglucosides; Methylglycosides; Rats; Theophylline; Time Factors; Triglycerides

1978
[Comparative studies on the effect of commercial lipid-lowering substances on the lipolysis of isolated rat and human fat cells].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adipose Tissue; Animals; Clofibrate; Humans; Insulin; Isoproterenol; Nicotinic Acids; Rats; Theophylline

1978
Effect of gemfibrozil in vitro on fat-mobilizing lipolysis in human adipose tissue.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69 Suppl 2

    Topics: Adipose Tissue; Clofibrate; Depression, Chemical; Humans; Hypolipidemic Agents; In Vitro Techniques; Isoproterenol; Lipid Metabolism; Lipid Mobilization; Norepinephrine; Theophylline; Valerates; Xylenes

1976
Potential antilipolytic activity of suloctidil.
    Die Naturwissenschaften, 1975, Volume: 62, Issue:3

    Topics: Adipose Tissue; Animals; Clofibrate; Epididymis; Fatty Acids, Nonesterified; In Vitro Techniques; Male; Nicotinic Acids; Norepinephrine; Propanolamines; Propranolol; Rats; Theophylline

1975
7-Substituted theophyllines. Part VI--N-[2-(4-chlorophenoxy)-1-phenyl-alkyl]-alkylamido derivatives.
    Farmaco (Societa chimica italiana : 1989), 1990, Volume: 45, Issue:6

    Topics: Animals; Anticholesteremic Agents; Blood Coagulation; Chemical Phenomena; Chemistry; Clofibrate; Diuresis; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Theophylline; Triglycerides

1990
The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:2

    Topics: Animals; Antipyrine; Benzoflavones; beta-Naphthoflavone; Clofibrate; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Theophylline; Valproic Acid; Warfarin

1988
Effects of clofibrate on water permeability and short-cicuit current of toad urinary bladder.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Biological Transport; Bufo marinus; Carbamazepine; Clofibrate; Cyclic AMP; In Vitro Techniques; Osmosis; Permeability; Sodium; Theophylline; Time Factors; Urinary Bladder; Vasopressins; Water

1980
Favourable effect of combined Miscleron-Xavin treatment on HDL-cholesterol level.
    Therapia Hungarica (English edition), 1983, Volume: 31, Issue:2

    Topics: Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Drug Therapy, Combination; Humans; Hyperlipoproteinemias; Theophylline; Triglycerides; Xanthinol Niacinate

1983
Xanthone analogues of clofibrate / Synthesis and biological evaluation as antagonists of lipolysis in vitro.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:5

    Topics: Adipose Tissue; Animals; Cells, Cultured; Clofibrate; Epinephrine; Lipolysis; Male; Rats; Rats, Inbred Strains; Theophylline

1982