Compounds > clofibrate

clofibrate and propylthiouracil

clofibrate has been researched along with propylthiouracil in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (37.50)	18.7374
1990's	1 (6.25)	18.2507
2000's	2 (12.50)	29.6817
2010's	7 (43.75)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kobayakawa, T; Osuga, K; Yasuda, H	1
Chinn, LJ; Salamon, KW	1
Auwerx, J; Staels, B; van Tol, A; Verhoeven, G	1
Cho, C; Linscheer, WG; Raheja, KL	1
Muñoz-Rodríguez, M; Torrano-San Francisco, F	1
Nowak, H; Simane, Z	1
Linscheer, WG; Patel, DG; Raheja, KL	1

Reviews

1 review(s) available for clofibrate and propylthiouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

15 other study(ies) available for clofibrate and propylthiouracil

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Experimental hyper-beta-lipoproteinemia and its amelioration by a novel hypolipidemic agent. Atherosclerosis, 1978, Volume: 30, Issue:3 Topics: Animals; Cholesterol; Cholesterol, Dietary; Clofibrate; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, LDL; Male; Oxazoles; Propylthiouracil; Rats; Triglycerides	1978
Potential hypolipidemic agents derived from 3-hydroxy-17,17-dimethylgona-1,3,5(10),8,11,13-hexaene. Journal of medicinal chemistry, 1977, Volume: 20, Issue:2 Topics: Animals; Cholesterol; Clofibrate; Female; Gonanes; Hypercholesterolemia; Hypolipidemic Agents; Male; Organ Size; Propylthiouracil; Rats; Triglycerides; Uterus	1977
Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific manner. Endocrinology, 1990, Volume: 126, Issue:4 Topics: Animals; Apolipoproteins A; Clofibrate; Ethinyl Estradiol; Female; Glucocorticoids; Hydrocortisone; Intestinal Mucosa; Intestines; Liver; Male; Ovariectomy; Propylthiouracil; Rats; Rats, Inbred Strains; RNA, Messenger; Thyroxine	1990
Propylthiouracil-induced hypothyroid hyperlipidemic chick: a model for clofibrate-induced toxicity. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 85, Issue:2 Topics: Animals; Chickens; Clofibrate; Hyperlipidemias; Hypothyroidism; Male; Muscles; Propylthiouracil	1986
[Clofibrate effect on thyroid function (author's transl)]. Revista espanola de fisiologia, 1973, Volume: 29, Issue:1 Topics: Animals; Chromatography, Paper; Clofibrate; Iodine; Iodine Radioisotopes; Male; Organ Size; Propylthiouracil; Rats; Thyroid Function Tests; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins	1973
Proceedings: Potentiating of lipid lowering activity of clofibrate by combining with low doses of 3-pyridylcarbinol in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl Topics: Animals; Cholesterol; Clofibrate; Diet; Drug Synergism; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Methanol; Propylthiouracil; Pyridines; Rats; Triglycerides	1974
Hypolipidemic and glycogenolytic effect of clofibrate (CPIB) in hypothyroid mice: role of insulin and glucagon. General pharmacology, 1982, Volume: 13, Issue:1 Topics: Animals; Clofibrate; Glucagon; Glycogen; Hypolipidemic Agents; Hypothyroidism; Insulin; Lipid Metabolism; Liver Glycogen; Male; Mice; Organ Size; Propylthiouracil	1982