clofibrate and propranolol

clofibrate has been researched along with propranolol in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's1 (3.45)18.2507
2000's4 (13.79)29.6817
2010's13 (44.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chung, EK; Deglin, JM; Deglin, SM1
Mustard, JF; Packham, MA1
Glick, G; Pick, R1
Short, D1
Mehta, J; Mehta, P1
Weiss, HJ1
Blaton, V; Ferenczi, M; Lambelin, G; Peeters, H; Roba, J; Roncucci, R; Vandamme, D1
Haller, H; Hanefeld, M; Julius, U; Leonhardt, W1
Matthews, MB; Turck, WP1
DeMets, DL; Friedman, LM; Furberg, C; May, GS; Passamani, E1
Horwitz, RI; Horwitz, SM1
Dokianakis, SN; Kornaros, ME; Lyberatos, G1

Reviews

7 review(s) available for clofibrate and propranolol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced cardiovascular diseases.
    Drugs, 1977, Volume: 14, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Antipsychotic Agents; Cardiovascular Diseases; Clofibrate; Contraceptives, Oral; Cyclophosphamide; Digitalis Glycosides; Doxorubicin; Estrogens; Humans; Hypoglycemic Agents; Lithium; Methysergide; Narcotic Antagonists; Narcotics; Phenothiazines; Phenytoin; Procainamide; Propranolol; Quinidine; Sympathomimetics

1977
Clinical pharmacology of platelets.
    Blood, 1977, Volume: 50, Issue:4

    Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation; Blood Platelets; Cell Membrane; Clofibrate; Cyproheptadine; Dipyridamole; Drug Therapy, Combination; Furosemide; Halofenate; Heparin; Humans; Hydrocortisone; Hydroxychloroquine; Methylprednisolone; Penicillin G; Platelet Aggregation; Propranolol; Prostaglandins; Sulfinpyrazone; Vitamin E

1977
Drugs in the management of angina pectoris.
    The Practitioner, 1969, Volume: 202, Issue:208

    Topics: Aerosols; Amyl Nitrite; Angina Pectoris; Clofibrate; Delayed-Action Preparations; Humans; Nitroglycerin; Propranolol; Verapamil

1969
The randomized clinical trial: bias in analysis.
    Circulation, 1981, Volume: 64, Issue:4

    Topics: Acute Disease; Alprenolol; Atenolol; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Humans; Myocardial Infarction; Patient Compliance; Placebos; Propranolol; Random Allocation; Sulfinpyrazone

1981
Adherence to treatment and health outcomes.
    Archives of internal medicine, 1993, Aug-23, Volume: 153, Issue:16

    Topics: Clofibrate; Double-Blind Method; Evaluation Studies as Topic; Humans; Hypercholesterolemia; Male; Myocardial Infarction; Patient Compliance; Propranolol; Randomized Controlled Trials as Topic; Treatment Outcome

1993

Trials

1 trial(s) available for clofibrate and propranolol

ArticleYear
The randomized clinical trial: bias in analysis.
    Circulation, 1981, Volume: 64, Issue:4

    Topics: Acute Disease; Alprenolol; Atenolol; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Humans; Myocardial Infarction; Patient Compliance; Placebos; Propranolol; Random Allocation; Sulfinpyrazone

1981

Other Studies

22 other study(ies) available for clofibrate and propranolol

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of propranolol, minoxidil, and clofibrate on cholesterol-induced atherosclerosis in stumptail macaques (Macaca arctoides).
    Atherosclerosis, 1977, Volume: 27, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Clofibrate; Coronary Disease; Coronary Vessels; Diet, Atherogenic; Disease Models, Animal; Haplorhini; Macaca; Male; Minoxidil; Propranolol; Pyrimidines

1977
The management of the patient with angina.
    American heart journal, 1977, Volume: 94, Issue:2

    Topics: Angina Pectoris; Anticoagulants; Clofibrate; Coronary Artery Bypass; Diazepam; Digoxin; Humans; Isosorbide Dinitrate; Nitroglycerin; Oxprenolol; Perhexiline; Prenylamine; Propranolol; Verapamil

1977
Status of antiplatelet drugs in coronary heart disease.
    JAMA, 1979, Jun-15, Volume: 241, Issue:24

    Topics: Aspirin; Blood Platelets; Clofibrate; Coronary Disease; Dipyridamole; Humans; Male; Models, Biological; Platelet Aggregation; Propranolol; Sulfinpyrazone

1979
Antiplatelet therapy (first of two parts).
    The New England journal of medicine, 1978, Jun-15, Volume: 298, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Blood Platelets; Cell Survival; Clofibrate; Dextrans; Dipyridamole; Heparin; Humans; Platelet Adhesiveness; Platelet Aggregation; Propranolol; Rabbits; Sulfinpyrazone; Thrombosis

1978
Potential antilipolytic activity of suloctidil.
    Die Naturwissenschaften, 1975, Volume: 62, Issue:3

    Topics: Adipose Tissue; Animals; Clofibrate; Epididymis; Fatty Acids, Nonesterified; In Vitro Techniques; Male; Nicotinic Acids; Norepinephrine; Propanolamines; Propranolol; Rats; Theophylline

1975
[Effect of propranolol and chlorophenoxybutyric acid (CPJB) on the dynamics of free fatty acids and blood sugar].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1972, Volume: 32, Issue:5

    Topics: Blood Glucose; Clofibrate; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Humans; Middle Aged; Propranolol

1972
Angina pectoris--II.
    British medical journal, 1971, Mar-06, Volume: 1, Issue:5748

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Cholesterol; Cholestyramine Resin; Clofibrate; Diet; Female; Heart Failure; Humans; Hyperlipidemias; Hyperthyroidism; Male; Middle Aged; Myocardium; Oxygen Consumption; Pacemaker, Artificial; Propranolol; Warfarin

1971
On the effect of pharmaceuticals on bacterial nitrite oxidation.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Bacteria, Anaerobic; Biodegradation, Environmental; Bioreactors; Carbamazepine; Cities; Clofibrate; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Kinetics; Nitrites; Nitrogen; Ofloxacin; Oxidation-Reduction; Pharmaceutical Preparations; Propranolol; Sewage; Sulfamethoxazole; Triclosan; Waste Disposal, Fluid; Water Purification

2004